Authors:
Wiley, MR
Weir, LC
Briggs, S
Bryan, NA
Buben, J
Campbell, C
Chirgadze, NY
Conrad, RC
Craft, TJ
Ficorilli, JV
Franciskovich, JB
Froelich, LL
Gifford-Moore, DS
Goodson, T
Herron, DK
Klimkowski, VJ
Kurz, KD
Kyle, JA
Masters, JJ
Ratz, AM
Milot, G
Shuman, RT
Smith, T
Smith, GF
Tebbe, AL
Tinsley, JM
Towner, RD
Wilson, A
Yee, YK
Citation: Mr. Wiley et al., Structure-based design of potent, amidine-derived inhibitors of factor Xa:Evaluation of selectivity, anticoagulant activity, and antithrombotic activity, J MED CHEM, 43(5), 2000, pp. 883-899
Authors:
Sall, DJ
Bailey, DL
Bastian, JA
Buben, JA
Chirgadze, NY
Clemens-Smith, AC
Denney, ML
Fisher, MJ
Giera, DD
Gifford-Moore, DS
Harper, RW
Johnson, LM
Klimkowski, VJ
Kohn, TJ
Lin, HS
McCowan, JR
Palkowitz, AD
Richett, ME
Smith, GF
Snyder, DW
Takeuchi, K
Toth, JE
Zhang, MS
Citation: Dj. Sall et al., Diamino benzo[b]thiophene derivatives as a novel class of active site directed thrombin inhibitors. 5. Potency, efficacy, and pharmacokinetic properties of modified C-3 side chain derivatives, J MED CHEM, 43(4), 2000, pp. 649-663
Authors:
Masters, JJ
Franciskovich, JB
Tinsley, JM
Campbell, C
Campbell, JB
Craft, TJ
Froelich, LL
Gifford-Moore, DS
Hay, LA
Herron, DK
Klimkowski, VJ
Kurz, KD
Metz, JT
Ratz, AM
Shuman, RT
Smith, GF
Smith, T
Towner, RD
Wiley, MR
Wilson, A
Yee, YK
Citation: Jj. Masters et al., Non-amidine-containing 1,2-dibenzamidobenzene inhibitors of human factor Xa with potent anticoagulant and antithrombotic activity, J MED CHEM, 43(11), 2000, pp. 2087-2092
Authors:
Zhang, MS
Bailey, DL
Bastian, JA
Briggs, SL
Chirgadze, NY
Clawson, DK
Denney, ML
Gifford-Moore, DS
Harper, RW
Johnson, LM
Klimkowski, VJ
Kohn, TJ
Lin, HS
McCowan, JR
Richett, ME
Sall, DJ
Smith, AJ
Smith, GF
Snyder, DW
Takeuchi, K
Utterback, BG
Yan, SCB
Citation: Ms. Zhang et al., Dibasic benzo[b]thiophene derivatives as a novel class of active site directed thrombin inhibitors: 2. Sidechain optimization and demonstration of invivo efficacy, BIOORG MED, 9(5), 1999, pp. 775-780
Authors:
Wiley, MR
Weir, LC
Briggs, SI
Chirgadze, NY
Clawson, D
Gifford-Moore, DS
Schacht, AL
Smith, GF
Vasudevan, V
Zornes, LL
Klimkowski, VJ
Citation: Mr. Wiley et al., The design of potent, selective, non-covalent, peptide thrombin inhibitorsutilizing imidazole as a S1 binding element, BIOORG MED, 9(18), 1999, pp. 2767-2772