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Results: 1-25 |
Results: 25
Activation of pro-(matrix metalloproteinase-2) (pro-MMP-2) by thrombin is membrane-type-MMP-dependent in human umbilical vein endothelial cells and generates a distinct 63 kDa active species
Authors: Lafleur, MA Hollenberg, MD Atkinson, SJ Knauper, V Murphy, G Edwards, DR
Citation: Ma. Lafleur et al., Activation of pro-(matrix metalloproteinase-2) (pro-MMP-2) by thrombin is membrane-type-MMP-dependent in human umbilical vein endothelial cells and generates a distinct 63 kDa active species, BIOCHEM J, 357, 2001, pp. 107-115
Characterization of the role of the "MT-loop" - An eight-amino acid insertion specific to progelatinase A (MMP2) activating membrane-type matrix metalloproteinases
Authors: English, WR Holtz, B Vogt, G Knauper, V Murphy, G
Citation: Wr. English et al., Characterization of the role of the "MT-loop" - An eight-amino acid insertion specific to progelatinase A (MMP2) activating membrane-type matrix metalloproteinases, J BIOL CHEM, 276(45), 2001, pp. 42018-42026
Tyrosine 36 plays a critical role in the interaction of the AB loop of tissue inhibitor of metalloproteinases-2 with matrix metalloproteinase-14
Authors: Williamson, RA Hutton, M Vogt, G Rapti, M Knauper, V Carr, MD Murphy, G
Citation: Ra. Williamson et al., Tyrosine 36 plays a critical role in the interaction of the AB loop of tissue inhibitor of metalloproteinases-2 with matrix metalloproteinase-14, J BIOL CHEM, 276(35), 2001, pp. 32966-32970
Identification and enzymatic characterization of two diverging murine counterparts of human interstitial collagenase (MMP-1) expressed at sites of embryo implantation
Authors: Balbin, M Fueyo, A Knauper, V Lopez, JM Alvarez, J Sanchez, LM Quesada, V Bordallo, J Murphy, G Lopez-Otin, C
Citation: M. Balbin et al., Identification and enzymatic characterization of two diverging murine counterparts of human interstitial collagenase (MMP-1) expressed at sites of embryo implantation, J BIOL CHEM, 276(13), 2001, pp. 10253-10262
Specific collagenolysis by gelatinase A, MMP-2, is determined by the hemopexin domain and not the fibronectin-like domain
Authors: Patterson, ML Atkinson, SJ Knauper, V Murphy, G
Citation: Ml. Patterson et al., Specific collagenolysis by gelatinase A, MMP-2, is determined by the hemopexin domain and not the fibronectin-like domain, FEBS LETTER, 503(2-3), 2001, pp. 158-162
Catalytic activities of membrane-type 6 matrix metalloproteinase (MMP25)
Authors: English, WR Velasco, G Stracke, JO Knauper, V Murphy, G
Citation: Wr. English et al., Catalytic activities of membrane-type 6 matrix metalloproteinase (MMP25), FEBS LETTER, 491(1-2), 2001, pp. 137-142
The role of exon 5 in fibroblast collagenase (MMP-1) substrate specificityand inhibitor selectivity
Authors: Knauper, V Patterson, ML Gomis-Ruth, FX Smith, B Lyons, A Docherty, AJP Murphy, G
Citation: V. Knauper et al., The role of exon 5 in fibroblast collagenase (MMP-1) substrate specificityand inhibitor selectivity, EUR J BIOCH, 268(6), 2001, pp. 1888-1896
Differential expression and localization of TIMP-1 and TIMP-4 in human gliomas
Authors: Groft, LL Muzik, H Rewcastle, NB Johnston, RN Knauper, V Lafleur, MA Forsyth, PA Edwards, DR
Citation: Ll. Groft et al., Differential expression and localization of TIMP-1 and TIMP-4 in human gliomas, BR J CANC, 85(1), 2001, pp. 55-63
Full-length and N-TIMP-3 display equal inhibitory activities toward TNF-alpha convertase
Authors: Lee, MH Knauper, V Becherer, JD Murphy, G
Citation: Mh. Lee et al., Full-length and N-TIMP-3 display equal inhibitory activities toward TNF-alpha convertase, BIOC BIOP R, 280(3), 2001, pp. 945-950
Cellular mechanisms for focal proteolysis and the regulation of the microenvironment
Authors: Murphy, G Knauper, V Atkinson, S Gavrilovic, J Edwards, D
Citation: G. Murphy et al., Cellular mechanisms for focal proteolysis and the regulation of the microenvironment, FIBRINOL PR, 14(2-3), 2000, pp. 165-174
Recognition and catabolism of synthetic heterotrimeric collagen peptides by matrix metalloproteinases
Authors: Ottl, J Gabriel, D Murphy, G Knauper, V Tominaga, Y Nagase, H Kroger, M Tschesche, H Bode, W Moroder, L
Citation: J. Ottl et al., Recognition and catabolism of synthetic heterotrimeric collagen peptides by matrix metalloproteinases, CHEM BIOL, 7(2), 2000, pp. 119-132
An analysis of two refolding routes for a C-terminally truncated human collagenase-3 expressed in Escherichia coli
Authors: Hardern, IM Knauper, V Ernill, RJ Taylor, IWF Cooper, KL Abbott, WM
Citation: Im. Hardern et al., An analysis of two refolding routes for a C-terminally truncated human collagenase-3 expressed in Escherichia coli, PROT EX PUR, 19(2), 2000, pp. 246-252
One-step sandwich enzyme immunoassay using monoclonal antibodies for detection of human enamelysin (MMP-20)
Authors: Wang, T Aoki, T Iwata, K Takata, T Uchida, T Knauper, V Llano, E Okada, Y Bartlett, JD
Citation: T. Wang et al., One-step sandwich enzyme immunoassay using monoclonal antibodies for detection of human enamelysin (MMP-20), EUR J OR SC, 108(6), 2000, pp. 530-537
Collagen degradation and platelet-derived growth factor stimulate the migration of vascular smooth muscle cells
Authors: Stringa, E Knauper, V Murphy, G Gavrilovic, J
Citation: E. Stringa et al., Collagen degradation and platelet-derived growth factor stimulate the migration of vascular smooth muscle cells, J CELL SCI, 113(11), 2000, pp. 2055-2064
Locatization of the death domain of tissue inhibitor of metalloproteinase-3 to the N terminus - Metalloproteinase inhibition is associated with proapoptotic activity
Authors: Bond, P Murphy, G Bennett, MR Amour, A Knauper, V Newby, AC Baker, AH
Citation: P. Bond et al., Locatization of the death domain of tissue inhibitor of metalloproteinase-3 to the N terminus - Metalloproteinase inhibition is associated with proapoptotic activity, J BIOL CHEM, 275(52), 2000, pp. 41358-41363
Biochemical characterization of the catalytic domain of human matrix metalloproteinase 19 - Evidence for a role as a potent basement membrane degrading enzyme
Authors: Stracke, JO Hutton, M Stewart, M Pendas, AM Smith, B Lopez-Otin, C Murphy, G Knauper, V
Citation: Jo. Stracke et al., Biochemical characterization of the catalytic domain of human matrix metalloproteinase 19 - Evidence for a role as a potent basement membrane degrading enzyme, J BIOL CHEM, 275(20), 2000, pp. 14809-14816
Membrane type 4 matrix metalloproteinase (MMP17) has tumor necrosis factor-alpha convertase activity but does not activate pro-MMP2
Authors: English, WR Puente, XS Freije, JMP Knauper, V Amour, A Merryweather, A Lopez-Otin, C Murphy, G
Citation: Wr. English et al., Membrane type 4 matrix metalloproteinase (MMP17) has tumor necrosis factor-alpha convertase activity but does not activate pro-MMP2, J BIOL CHEM, 275(19), 2000, pp. 14046-14055
Matrix metalloproteinases 19 and 20 cleave aggrecan and cartilage oligomeric matrix protein (COMP)
Authors: Stracke, JO Fosang, AJ Last, K Mercuri, FA Pendas, AM Llano, E Perris, R Di Cesare, PE Murphy, G Knauper, V
Citation: Jo. Stracke et al., Matrix metalloproteinases 19 and 20 cleave aggrecan and cartilage oligomeric matrix protein (COMP), FEBS LETTER, 478(1-2), 2000, pp. 52-56
The in vitro activity of ADAM-10 is inhibited by TIMP-1 and TIMP-3
Authors: Amour, A Knight, CG Webster, A Slocombe, PM Stephens, PE Knauper, V Docherty, AJP Murphy, G
Citation: A. Amour et al., The in vitro activity of ADAM-10 is inhibited by TIMP-1 and TIMP-3, FEBS LETTER, 473(3), 2000, pp. 275-279
Methods for studying activation of matrix metalloproteinases
Authors: Knauper, V Murphy, G
Citation: V. Knauper et G. Murphy, Methods for studying activation of matrix metalloproteinases, METH MOL B, 151, 2000, pp. 377-387
Mechanisms for pro matrix metalloproteinase activation
Authors: Murphy, G Stanton, H Cowell, S Butler, G Knauper, V Atkinson, S Gavrilovic, J
Citation: G. Murphy et al., Mechanisms for pro matrix metalloproteinase activation, APMIS, 107(1), 1999, pp. 38-44
Phosphinic pseudo-tripeptides as potent inhibitors of matrix metalloproteinases: A structure-activity study
Authors: Vassiliou, S Mucha, A Cuniasse, P Georgiadis, D Lucet-Levannier, K Beau, F Kannan, R Murphy, G Knauper, V Rio, MC Basset, P Yiotakis, A Dive, V
Citation: S. Vassiliou et al., Phosphinic pseudo-tripeptides as potent inhibitors of matrix metalloproteinases: A structure-activity study, J MED CHEM, 42(14), 1999, pp. 2610-2620
Cloning and characterization of human MMP-23, a new matrix metalloproteinase predominantly expressed in reproductive tissues and lacking conserved domains in other family members
Authors: Velasco, G Pendas, AM Fueyo, A Knauper, V Murphy, G Lopez-Otin, C
Citation: G. Velasco et al., Cloning and characterization of human MMP-23, a new matrix metalloproteinase predominantly expressed in reproductive tissues and lacking conserved domains in other family members, J BIOL CHEM, 274(8), 1999, pp. 4570-4576
The specificity of TIMP-2 for matrix metalloproteinases can be modified bysingle amino acid mutations
Authors: Butler, GS Hutton, M Wattam, BA Williamson, RA Knauper, V Willenbrock, F Murphy, G
Citation: Gs. Butler et al., The specificity of TIMP-2 for matrix metalloproteinases can be modified bysingle amino acid mutations, J BIOL CHEM, 274(29), 1999, pp. 20391-20396
Identification and characterization of human MT5-MMP, a new membrane-boundactivator of progelatinase A overexpressed in brain tumors
Authors: Llano, P Pendas, AM Freije, JP Nakano, A Knauper, V Murphy, G Lopez-Otin, C
Citation: P. Llano et al., Identification and characterization of human MT5-MMP, a new membrane-boundactivator of progelatinase A overexpressed in brain tumors, CANCER RES, 59(11), 1999, pp. 2570-2576
Risultati: 1-25 |