Authors:
Weggen, S
Eriksen, JL
Das, P
Sagi, SA
Wang, R
Pietrzik, CU
Findlay, KA
Smith, TW
Murphy, MP
Butler, T
Kang, DE
Marquez-Sterling, N
Golde, TE
Koo, EH
Citation: S. Weggen et al., A subset of NSAIDs lower amyloidogenic A beta 42 independently of cyclooxygenase activity, NATURE, 414(6860), 2001, pp. 212-216
Authors:
Xia, XF
Qian, S
Soriano, S
Wu, Y
Fletcher, AM
Wang, XJ
Koo, EH
Wu, XW
Zheng, H
Citation: Xf. Xia et al., Loss of presenilin 1 is associated with enhanced beta-catenin signaling and skin tumorigenesis, P NAS US, 98(19), 2001, pp. 10863-10868
Authors:
Soriano, S
Lu, DC
Chandra, S
Pietrzik, CU
Koo, EH
Citation: S. Soriano et al., The amyloidogenic pathway of amyloid precursor protein (APP) is independent of its cleavage by caspases, J BIOL CHEM, 276(31), 2001, pp. 29045-29050
Authors:
Zhu, GF
Wang, D
Lin, YH
McMahon, T
Koo, EH
Messing, RO
Citation: Gf. Zhu et al., Protein kinase C epsilon suppresses A beta production and promotes activation of alpha-secretase, BIOC BIOP R, 285(4), 2001, pp. 997-1006
Authors:
Kang, DE
Pietrzik, CU
Baum, L
Chevallier, N
Merriam, DE
Kounnas, MZ
Wagner, SL
Troncoso, JC
Kawas, CH
Katzman, R
Koo, EH
Citation: De. Kang et al., Modulation of amyloid beta-protein clearance and Alzheimer's disease susceptibility by the LDL receptor-related protein pathway, J CLIN INV, 106(9), 2000, pp. 1159-1166
Authors:
Saura, CA
Tomita, T
Soriano, S
Takahashi, M
Leem, JY
Honda, T
Koo, EH
Iwatsubo, T
Thinakaran, G
Citation: Ca. Saura et al., The nonconserved hydrophilic loop domain of presenilin (PS) is not required for PS endoproteolysis or enhanced A beta 42 production mediated by familial early onset Alzheimer's disease-linked PS variants, J BIOL CHEM, 275(22), 2000, pp. 17136-17142
Authors:
Kuo, YM
Kokjohn, TA
Kalback, W
Luehrs, D
Galasko, DR
Chevallier, N
Koo, EH
Emmerling, MR
Roher, AE
Citation: Ym. Kuo et al., Amyloid-beta peptides interact with plasma proteins and erythrocytes: Implications for their quantitation in plasma, BIOC BIOP R, 268(3), 2000, pp. 750-756
Authors:
Kang, DE
Soriano, S
Frosch, MP
Collins, T
Naruse, S
Sisodia, SS
Leibowitz, G
Levine, F
Koo, EH
Citation: De. Kang et al., Presenilin 1 facilitates the constitutive turnover of beta-catenin: Differential activity of Alzheimer's disease-linked PS1 mutants in the beta-catenin-signaling pathway, J NEUROSC, 19(11), 1999, pp. 4229-4237
Authors:
Yuan, H
Zhai, P
Anderson, LM
Pan, J
Thimmapaya, B
Koo, EH
Marquez-Sterling, NR
Citation: H. Yuan et al., Recombinant adenovirus is an appropriate vector for endocytotic protein trafficking studies in cultured neurons, J NEUROSC M, 88(1), 1999, pp. 45-54
Citation: S. Soriano et al., Expression of beta-amyloid precursor protein-CD3 gamma chimeras to demonstrate the selective generation of amyloid beta(1-40) and amyloid beta(1-42) peptides within secretory and endocytic compartments, J BIOL CHEM, 274(45), 1999, pp. 32295-32300
Authors:
Perez, RG
Soriano, S
Hayes, JD
Ostaszewski, B
Xia, WM
Selkoe, DJ
Chen, XH
Stokin, GB
Koo, EH
Citation: Rg. Perez et al., Mutagenesis identifies new signals for beta-amyloid precursor protein endocytosis, turnover, and the generation of secreted fragments, including A beta 42, J BIOL CHEM, 274(27), 1999, pp. 18851-18856
Authors:
Xia, WM
Zhang, JM
Ostaszewski, BL
Kimberly, WT
Seubert, P
Koo, EH
Shen, J
Selkoe, DJ
Citation: Wm. Xia et al., Presenilin 1 regulates the processing of beta-amyloid precursor protein C-terminal fragments and the generation of amyloid beta-protein in endoplasmic reticulum and Golgi, BIOCHEM, 37(47), 1998, pp. 16465-16471