Authors:
Salmon-Chemin, L
Buisine, E
Yardley, V
Kohler, S
Debreu, MA
Landry, V
Sergheraert, C
Croft, SL
Krauth-Siegel, RL
Davioud-Charvet, E
Citation: L. Salmon-chemin et al., 2-and 3-substituted 1,4-naphthoquinone derivatives as subversive substrates of trypanothione reductase and lipoamide dehydrogenase from Trypanosoma cruzi: Synthesis and correlation between redox cycling activities and in vitro cytotoxicity, J MED CHEM, 44(4), 2001, pp. 548-565
Authors:
Dormeyer, M
Reckenfelderbaumer, N
Ludemann, H
Krauth-Siegel, RL
Citation: M. Dormeyer et al., Trypanothione-dependent synthesis of deoxyribonucleotides by Trypanosoma brucei ribonucleotide reductase, J BIOL CHEM, 276(14), 2001, pp. 10602-10606
Citation: J. Gutierrez-correa et al., Trypanosoma cruzi dihydrolipoamide dehydrogenase is inactivated by myeloperoxidase-generated "reactive species", FREE RAD RE, 33(1), 2000, pp. 13-22
Authors:
Krieger, S
Schwarz, W
Ariyanayagam, MR
Fairlamb, AH
Krauth-Siegel, RL
Clayton, C
Citation: S. Krieger et al., Trypanosomes lacking trypanothione reductase are avirulent and show increased sensitivity to oxidative stress, MOL MICROB, 35(3), 2000, pp. 542-552
Authors:
Bonse, S
Richards, JM
Ross, SA
Lowe, G
Krauth-Siegel, RL
Citation: S. Bonse et al., (2,2 ': 6 ',2 ''-terpyridine)platinum(II) complexes are irreversible inhibitors of Trypanosoma cruzi trypanothione reductase but not of human glutathione reductase, J MED CHEM, 43(25), 2000, pp. 4812-4821
Authors:
Reckenfelderbaumer, N
Ludemann, H
Schmidt, H
Steverding, D
Krauth-Siegel, RL
Citation: N. Reckenfelderbaumer et al., Identification and functional characterization of thioredoxin from Trypanosoma brucei brucei, J BIOL CHEM, 275(11), 2000, pp. 7547-7552
Authors:
Breidbach, T
Krauth-Siegel, RL
Steverding, D
Citation: T. Breidbach et al., Ribonucleotide reductase is regulated via the R2 subunit during the life cycle of Trypanosoma brucei, FEBS LETTER, 473(2), 2000, pp. 212-216
Authors:
Gallwitz, H
Bonse, S
Martinez-Cruz, A
Schlichting, I
Schumacher, K
Krauth-Siegel, RL
Citation: H. Gallwitz et al., Ajoene is an inhibitor and subversive substrate of human glutathione reductase and Trypanosoma cruzi trypanothione reductase: Crystallographic, kinetic, and spectroscopic studies, J MED CHEM, 42(3), 1999, pp. 364-372
Authors:
Bonse, S
Santelli-Rouvier, C
Barbe, J
Krauth-Siegel, RL
Citation: S. Bonse et al., Inhibition of Trypanosoma cruzi trypanothione reductase by acridines: Kinetic studies and structure-activity relationships, J MED CHEM, 42(26), 1999, pp. 5448-5454
Authors:
Blumenstiel, K
Schoneck, R
Yardley, V
Croft, SL
Krauth-Siegel, RL
Citation: K. Blumenstiel et al., Nitrofuran drugs as common subversive substrates of Trypanosoma cruzi lipoamide dehydrogenase and trypanothione reductase, BIOCH PHARM, 58(11), 1999, pp. 1791-1799
Authors:
Wagner, JT
Ludemann, H
Farber, PM
Lottspeich, F
Krauth-Siegel, RL
Citation: Jt. Wagner et al., Glutamate dehydrogenase, the marker protein of Plasmodium falciparum - Cloning, expression and characterization of the malarial enzyme, EUR J BIOCH, 258(2), 1998, pp. 813-819