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Results: 1-10 |
Results: 10
Vinflunine, the latest Vinca alkaloid in clinical development - A review of its preclinical anticancer properties
Authors: Kruczynski, A Hill, BT
Citation: A. Kruczynski et Bt. Hill, Vinflunine, the latest Vinca alkaloid in clinical development - A review of its preclinical anticancer properties, CR R ONC H, 40(2), 2001, pp. 159-173
Markedly diminished drug resistance-inducing properties of vinflunine (20 ',20 '-difluoro-3 ',4 '-dihydrovinorelbine) relative to vinorelbine, identified in murine and human tumour cells in vivo and in vitro
Authors: Etievant, C Kruczynski, A Barret, JM Tait, AS Kavallaris, M Hill, BT
Citation: C. Etievant et al., Markedly diminished drug resistance-inducing properties of vinflunine (20 ',20 '-difluoro-3 ',4 '-dihydrovinorelbine) relative to vinorelbine, identified in murine and human tumour cells in vivo and in vitro, CANC CHEMOT, 48(1), 2001, pp. 62-70
Inhibition of RAS-targeted prenylation: protein farnesyl transferase inhibitors revisited
Authors: Hill, BT Perrin, D Kruczynski, A
Citation: Bt. Hill et al., Inhibition of RAS-targeted prenylation: protein farnesyl transferase inhibitors revisited, CR R ONC H, 33(1), 2000, pp. 7-23
Characterization of the biological and biochemical activities of F 11782 and the bisdioxopiperazines, ICRF-187 and ICRF-193, two types of topoisomerase II catalytic inhibitors with distinctive mechanisms of action
Authors: van Hille, B Etievant, C Barret, JM Kruczynski, A Hill, BT
Citation: B. Van Hille et al., Characterization of the biological and biochemical activities of F 11782 and the bisdioxopiperazines, ICRF-187 and ICRF-193, two types of topoisomerase II catalytic inhibitors with distinctive mechanisms of action, ANTI-CANC D, 11(10), 2000, pp. 829-841
F 11782, a dual inhibitor of topoisomerases I and II with an original mechanism of action in vitro, and markedly superior in vivo antitumour activity, relative to three other dual topoisomerase inhibitors, intoplicin, aclarubicin and TAS-103
Authors: Etievant, C Kruczynski, A Barret, JM Perrin, D van Hille, B Guminski, Y Hill, BT
Citation: C. Etievant et al., F 11782, a dual inhibitor of topoisomerases I and II with an original mechanism of action in vitro, and markedly superior in vivo antitumour activity, relative to three other dual topoisomerase inhibitors, intoplicin, aclarubicin and TAS-103, CANC CHEMOT, 46(2), 2000, pp. 101-113
Detection of DNA-strand breaks in cells treated with F 11782, a catalytic inhibitor of topoisomerases I and II
Authors: Barret, JM Montaudon, D Etievant, C Perrin, D Kruczynski, A Robert, J Hill, BT
Citation: Jm. Barret et al., Detection of DNA-strand breaks in cells treated with F 11782, a catalytic inhibitor of topoisomerases I and II, ANTICANC R, 20(6B), 2000, pp. 4557-4562
Preclinical antitumour activity of F 11782, a novel dual catalytic inhibitor of topoisomerases
Authors: Kruczynski, A Etievant, C Perrin, D Imbert, T Colpaert, F Hill, BT
Citation: A. Kruczynski et al., Preclinical antitumour activity of F 11782, a novel dual catalytic inhibitor of topoisomerases, BR J CANC, 83(11), 2000, pp. 1516-1524
F 11782, a novel epipodophylloid non-intercalating dual catalytic inhibitor of topoisomerases I and II with an original mechanism of action
Authors: Perrin, D van Hille, B Barret, JM Kruczynski, A Etievant, C Imbert, T Hill, BT
Citation: D. Perrin et al., F 11782, a novel epipodophylloid non-intercalating dual catalytic inhibitor of topoisomerases I and II with an original mechanism of action, BIOCH PHARM, 59(7), 2000, pp. 807-819
Superior in vivo experimental antitumour activity of vinflunine, relative to vinorelbine, in a panel of human tumour xenografts
Authors: Hill, BT Fiebig, HH Waud, WR Poupon, MF Colpaert, F Kruczynski, A
Citation: Bt. Hill et al., Superior in vivo experimental antitumour activity of vinflunine, relative to vinorelbine, in a panel of human tumour xenografts, EUR J CANC, 35(3), 1999, pp. 512-520
Vinflunine, a new vinca alkaloid: cytotoxicity, cellular accumulation and action on the interphasic and mitotic microtubule cytoskeleton of PtK2 cells
Authors: Jean-Decoster, C Brichese, L Barret, JM Tollon, Y Kruczynski, A Hill, BT Wright, M
Citation: C. Jean-decoster et al., Vinflunine, a new vinca alkaloid: cytotoxicity, cellular accumulation and action on the interphasic and mitotic microtubule cytoskeleton of PtK2 cells, ANTI-CANC D, 10(6), 1999, pp. 537-543
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