Authors:
Doucet-Personeni, C
Bentley, PD
Fletcher, RJ
Kinkaid, A
Kryger, G
Pirard, B
Taylor, A
Taylor, R
Taylor, J
Viner, R
Silman, I
Sussman, JL
Greenblatt, HM
Lewis, T
Citation: C. Doucet-personeni et al., A structure-based design approach to the development of novel, reversible AChE inhibitors, J MED CHEM, 44(20), 2001, pp. 3203-3215
Authors:
Hadfield, A
Shammas, C
Kryger, G
Ringe, D
Petsko, GA
Ouyang, J
Viola, RE
Citation: A. Hadfield et al., Active site analysis of the potential antimicrobial target aspartate semialdehyde dehydrogenase, BIOCHEM, 40(48), 2001, pp. 14475-14483
Authors:
Harel, M
Kryger, G
Rosenberry, TL
Mallender, WD
Lewis, T
Fletcher, RJ
Guss, JM
Silman, I
Sussman, JL
Citation: M. Harel et al., Three-dimensional structures of Drosophila melanogaster acetylcholinesterase and of its complexes with two potent inhibitors, PROTEIN SCI, 9(6), 2000, pp. 1063-1072
Authors:
Kryger, G
Harel, M
Giles, K
Toker, L
Velan, B
Lazar, A
Kronman, C
Barak, D
Ariel, N
Shafferman, A
Silman, I
Sussman, JL
Citation: G. Kryger et al., Structures of recombinant native and E202Q mutant human acetylcholinesterase complexed with the snake-venom toxin fasciculin-II, ACT CRYST D, 56, 2000, pp. 1385-1394
Authors:
Koellner, G
Kryger, G
Millard, CB
Silman, I
Sussman, JL
Steiner, T
Citation: G. Koellner et al., Active-site gorge and buried water molecules in crystal structures of acetylcholinesterase from Torpedo californica, J MOL BIOL, 296(2), 2000, pp. 713-735
Citation: G. Kryger et al., Structure of acetylcholinesterase complexed with E2020 (Aricept (R)): implications for the design of new anti-Alzheimer drugs, STRUCT F D, 7(3), 1999, pp. 297-307
Authors:
Hadfield, A
Kryger, G
Ouyang, J
Petsko, GA
Ringe, D
Viola, R
Citation: A. Hadfield et al., Structure of aspartate-beta-semialdehyde dehydrogenase from Escherichia coli, a key enzyme in the aspartate family of amino acid biosynthesis, J MOL BIOL, 289(4), 1999, pp. 991-1002
Authors:
Greenblatt, HM
Kryger, G
Lewis, T
Silman, I
Sussman, JL
Citation: Hm. Greenblatt et al., Structure of acetylcholinesterase complexed with (-)-galanthamine at 2.3 angstrom resolution, FEBS LETTER, 463(3), 1999, pp. 321-326
Authors:
Millard, CB
Kryger, G
Ordentlich, A
Greenblatt, HM
Harel, M
Raves, ML
Segall, Y
Barak, D
Shafferman, A
Silman, I
Sussman, JL
Citation: Cb. Millard et al., Crystal structures of aged phosphonylated acetylcholinesterase: Nerve agent reaction products at the atomic level, BIOCHEM, 38(22), 1999, pp. 7032-7039