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Results: 1-25 | 26-33
Results: 1-25/33
DIFFERENTIAL ACTIVITIES OF SECRETED LYMPHOTOXIN-ALPHA(3) AND MEMBRANELYMPHOTOXIN-ALPHA(1)BETA(2) IN LYMPHOTOXIN-INDUCED INFLAMMATION - CRITICAL ROLE OF TNF RECEPTOR-1 SIGNALING
Authors: SACCA R CUFF CA LESSLAUER W RUDDLE NH
Citation: R. Sacca et al., DIFFERENTIAL ACTIVITIES OF SECRETED LYMPHOTOXIN-ALPHA(3) AND MEMBRANELYMPHOTOXIN-ALPHA(1)BETA(2) IN LYMPHOTOXIN-INDUCED INFLAMMATION - CRITICAL ROLE OF TNF RECEPTOR-1 SIGNALING, The Journal of immunology, 160(1), 1998, pp. 485-491
RSK-B, A NOVEL RIBOSOMAL S6 KINASE FAMILY MEMBER, IS A CREB KINASE UNDER DOMINANT CONTROL OF P38-ALPHA MITOGEN-ACTIVATED PROTEIN-KINASE (P38-ALPHA(MAPK))
Authors: PIERRAT B CORREIA JD MARY JL TOMASZUBER M LESSLAUER W
Citation: B. Pierrat et al., RSK-B, A NOVEL RIBOSOMAL S6 KINASE FAMILY MEMBER, IS A CREB KINASE UNDER DOMINANT CONTROL OF P38-ALPHA MITOGEN-ACTIVATED PROTEIN-KINASE (P38-ALPHA(MAPK)), The Journal of biological chemistry, 273(45), 1998, pp. 29661-29671
ANASSESSMENT OF THE EFFECT OF ANTI-DRUG ANTIBODY-FORMATION ON THE PHARMACOKINETICS AND PHARMACODYNAMICS OF STNFR55-IGG (RO 45-2081-LENERCEPT [LEN]) (S.C.) IN PATIENTS WITH RHEUMATOID-ARTHRITIS (RA)
Authors: KNEER J LEUDIN E LESSLAUER W BIRNBOECK H STEVENS RM
Citation: J. Kneer et al., ANASSESSMENT OF THE EFFECT OF ANTI-DRUG ANTIBODY-FORMATION ON THE PHARMACOKINETICS AND PHARMACODYNAMICS OF STNFR55-IGG (RO 45-2081-LENERCEPT [LEN]) (S.C.) IN PATIENTS WITH RHEUMATOID-ARTHRITIS (RA), Arthritis and rheumatism, 41(9), 1998, pp. 155-155
IMMUNOGENICITY OF A HUMAN TNFR55-IGG1 FUSION PROTEIN (LENERCEPT) IN RHEUMATOID-ARTHRITIS (RA) AND MULTIPLE-SCLEROSIS (MS) PATIENTS
Authors: CHRISTEN U THUERKAUF R STEVENS R LESSLAUER W
Citation: U. Christen et al., IMMUNOGENICITY OF A HUMAN TNFR55-IGG1 FUSION PROTEIN (LENERCEPT) IN RHEUMATOID-ARTHRITIS (RA) AND MULTIPLE-SCLEROSIS (MS) PATIENTS, Arthritis and rheumatism, 41(9), 1998, pp. 156-156
TNF-ALPHA RECEPTOR FUSION PROTEIN PREVENTS EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS AND DEMYELINATION IN LEWIS RATS - AN OVERVIEW
Authors: KLINKERT WEF KOJIMA K LESSLAUER W RINNER W LASSMANN H WEKERLE H
Citation: Wef. Klinkert et al., TNF-ALPHA RECEPTOR FUSION PROTEIN PREVENTS EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS AND DEMYELINATION IN LEWIS RATS - AN OVERVIEW, Journal of neuroimmunology, 72(2), 1997, pp. 163-168
P55 TUMOR-NECROSIS-FACTOR RECEPTOR FUSION PROTEIN IN THE TREATMENT OFPATIENTS WITH SEVERE SEPSIS AND SEPTIC SHOCK - A RANDOMIZED CONTROLLED MULTICENTER TRIAL
Authors: ABRAHAM E GLAUSER MP BUTLER T GARBINO J GELMONT D LATERRE PF KUDSK K BRUINING HA OTTO C TOBIN E ZWINGELSTEIN C LESSLAUER W LEIGHTON A
Citation: E. Abraham et al., P55 TUMOR-NECROSIS-FACTOR RECEPTOR FUSION PROTEIN IN THE TREATMENT OFPATIENTS WITH SEVERE SEPSIS AND SEPTIC SHOCK - A RANDOMIZED CONTROLLED MULTICENTER TRIAL, JAMA, the journal of the American Medical Association, 277(19), 1997, pp. 1531-1538
PRETREATMENT WITH A 55-KDA TUMOR-NECROSIS-FACTOR RECEPTOR IMMUNOGLOBULIN FUSION PROTEIN ATTENUATES ACTIVATION OF COAGULATION, BUT NOT OF FIBRINOLYSIS, DURING LETHAL BACTEREMIA IN BABOONS
Authors: VANDERPOLL T JANSEN PM VANZEE KJ HACK CE OLDENBURG HA LOETSCHER H LESSLAUER W LOWRY SF MOLDAWER LL
Citation: T. Vanderpoll et al., PRETREATMENT WITH A 55-KDA TUMOR-NECROSIS-FACTOR RECEPTOR IMMUNOGLOBULIN FUSION PROTEIN ATTENUATES ACTIVATION OF COAGULATION, BUT NOT OF FIBRINOLYSIS, DURING LETHAL BACTEREMIA IN BABOONS, The Journal of infectious diseases, 176(1), 1997, pp. 296-299
BLOCKADE OF P38 MITOGEN-ACTIVATED PROTEIN-KINASE PATHWAY INHIBITS INDUCIBLE NITRIC-OXIDE SYNTHASE EXPRESSION IN MOUSE ASTROCYTES
Authors: DASILVA J PIERRAT B MARY JL LESSLAUER W
Citation: J. Dasilva et al., BLOCKADE OF P38 MITOGEN-ACTIVATED PROTEIN-KINASE PATHWAY INHIBITS INDUCIBLE NITRIC-OXIDE SYNTHASE EXPRESSION IN MOUSE ASTROCYTES, The Journal of biological chemistry, 272(45), 1997, pp. 28373-28380
HIGH-SENSITIVITY OF TRANSGENIC MICE EXPRESSING SOLUBLE TNFR1 FUSION PROTEIN TO MYCOBACTERIAL INFECTIONS - SYNERGISTIC ACTION OF TNF AND IFN-GAMMA IN THE DIFFERENTIATION OF PROTECTIVE GRANULOMAS
Authors: GARCIA I MIYAZAKI Y MARCHAL G LESSLAUER W VASSALLI P
Citation: I. Garcia et al., HIGH-SENSITIVITY OF TRANSGENIC MICE EXPRESSING SOLUBLE TNFR1 FUSION PROTEIN TO MYCOBACTERIAL INFECTIONS - SYNERGISTIC ACTION OF TNF AND IFN-GAMMA IN THE DIFFERENTIATION OF PROTECTIVE GRANULOMAS, European Journal of Immunology, 27(12), 1997, pp. 3182-3190
TUMOR NECROSIS FACTOR-ALPHA-INDUCED EXPRESSION OF HEAT-SHOCK-PROTEIN-72 IN ADULT FELINE CARDIAC MYOCYTES
Authors: NAKANO M KNOWLTON AA YOKOYAMA T LESSLAUER W MANN DL
Citation: M. Nakano et al., TUMOR NECROSIS FACTOR-ALPHA-INDUCED EXPRESSION OF HEAT-SHOCK-PROTEIN-72 IN ADULT FELINE CARDIAC MYOCYTES, American journal of physiology. Heart and circulatory physiology, 39(4), 1996, pp. 1231-1239
ATTENUATION OF COLLAGEN-INDUCED ARTHRITIS IN 55-KDA TNF RECEPTOR-TYPE-1 (TNFR1)-IGG1-TREATED AND TNFR1-DEFICIENT MICE
Authors: MORI L ISELIN S DELIBERO G LESSLAUER W
Citation: L. Mori et al., ATTENUATION OF COLLAGEN-INDUCED ARTHRITIS IN 55-KDA TNF RECEPTOR-TYPE-1 (TNFR1)-IGG1-TREATED AND TNFR1-DEFICIENT MICE, The Journal of immunology, 157(7), 1996, pp. 3178-3182
PROTECTION AGAINST LETHAL ESCHERICHIA-COLI BACTEREMIA IN BABOONS (PAPIO-ANUBIS) BY PRETREATMENT WITH A 55-KDA TNF RECEPTOR (CD120A)-IG FUSION PROTEIN, RO-45-2081
Authors: VANZEE KJ MOLDAWER LL OLDENBURG HSA THOMPSON WA STACKPOLE SA MONTEGUT WJ ROGY MA MESCHTER C GALLATI H SCHILLER CD RICHTER WF LOETSCHER H ASHKENAZI A CHAMOW SM WURM F CALVANO SE LOWRY SF LESSLAUER W
Citation: Kj. Vanzee et al., PROTECTION AGAINST LETHAL ESCHERICHIA-COLI BACTEREMIA IN BABOONS (PAPIO-ANUBIS) BY PRETREATMENT WITH A 55-KDA TNF RECEPTOR (CD120A)-IG FUSION PROTEIN, RO-45-2081, The Journal of immunology, 156(6), 1996, pp. 2221-2230
A HUMAN TUMOR-NECROSIS-FACTOR P75 RECEPTOR AGONIST STIMULATES IN-VITRO T-CELL PROLIFERATION BUT DOES NOT PRODUCE INFLAMMATION OR SHOCK IN THE BABOON
Authors: WELBORN MB VANZEE K EDWARDS PD PRUITT JH KAIBARA A VAUTHEY JN ROGY M CASTLEMAN WL LOWRY SF KENNEY JS STUBER D ETTLIN U WIPF B LOETSCHER H COPELAND EM LESSLAUER W MOLDAWER LL
Citation: Mb. Welborn et al., A HUMAN TUMOR-NECROSIS-FACTOR P75 RECEPTOR AGONIST STIMULATES IN-VITRO T-CELL PROLIFERATION BUT DOES NOT PRODUCE INFLAMMATION OR SHOCK IN THE BABOON, The Journal of experimental medicine, 184(1), 1996, pp. 165-171
TUMOR-NECROSIS-FACTOR RECEPTORS (TNFR) IN MOUSE FIBROBLASTS DEFICIENTIN TNFR1 OR TNFR2 ARE SIGNALING COMPETENT AND ACTIVATE THE MITOGEN-ACTIVATED PROTEIN-KINASE PATHWAY WITH DIFFERENTIAL KINETICS
Authors: KALB A BLUETHMANN H MOORE MW LESSLAUER W
Citation: A. Kalb et al., TUMOR-NECROSIS-FACTOR RECEPTORS (TNFR) IN MOUSE FIBROBLASTS DEFICIENTIN TNFR1 OR TNFR2 ARE SIGNALING COMPETENT AND ACTIVATE THE MITOGEN-ACTIVATED PROTEIN-KINASE PATHWAY WITH DIFFERENTIAL KINETICS, The Journal of biological chemistry, 271(45), 1996, pp. 28097-28104
TUMOR-NECROSIS-FACTOR-ALPHA INDUCES ACTIVATION OF COAGULATION AND FIBRINOLYSIS IN BABOONS THROUGH AN EXCLUSIVE EFFECT ON THE P55 RECEPTOR
Authors: VANDERPOLL T JANSEN PM VANZEE KJ WELBORN MB DEJONG I HACK CE LOETSCHER H LESSLAUER W LOWRY SF MOLDAWER LL
Citation: T. Vanderpoll et al., TUMOR-NECROSIS-FACTOR-ALPHA INDUCES ACTIVATION OF COAGULATION AND FIBRINOLYSIS IN BABOONS THROUGH AN EXCLUSIVE EFFECT ON THE P55 RECEPTOR, Blood, 88(3), 1996, pp. 922-927
NEUTRALIZATION OF TNF BY LENERCEPT (TNFR55-IGG1,RO-45-2081) IN PATIENTS WITH RHEUMATOID-ARTHRITIS TREATED FOR 3 MONTHS - RESULTS OF A EUROPEAN PHASE-II TRIAL
Authors: SANDER O RAU R VANRIEL P VANDEPUTTE L HASLER F BAUDIN M LUDIN E MCAULIFFE T DICKINSON S KAHNY MR LESSLAUER W VANDERAUWERA P
Citation: O. Sander et al., NEUTRALIZATION OF TNF BY LENERCEPT (TNFR55-IGG1,RO-45-2081) IN PATIENTS WITH RHEUMATOID-ARTHRITIS TREATED FOR 3 MONTHS - RESULTS OF A EUROPEAN PHASE-II TRIAL, Arthritis and rheumatism, 39(9), 1996, pp. 1288-1288
SAFETY AND EFFICACY OF TNF NEUTRALIZATION BY LENERCEPT (TNFR55-IGG1, RO-45-2081) IN PATIENTS WITH RHEUMATOID-ARTHRITIS EXPOSED TO A SINGLE-DOSE
Authors: HASLER F VANDEPUTTE L DUMONT E KNEER J BOCK J DICKINSON S LESSLAUER W VANDERAUWERA P
Citation: F. Hasler et al., SAFETY AND EFFICACY OF TNF NEUTRALIZATION BY LENERCEPT (TNFR55-IGG1, RO-45-2081) IN PATIENTS WITH RHEUMATOID-ARTHRITIS EXPOSED TO A SINGLE-DOSE, Arthritis and rheumatism, 39(9), 1996, pp. 1291-1291
NEUTRALIZATION OF TNF BY LENERCEPT (TNFR55-IGG1 RO-45-2081) IN PATIENTS WITH RHEUMATOID-ARTHRITIS TREATED FOR 3 MONTHS - RESULTS OF AN US PHASE-II TRIAL
Authors: FURST D WEISMAN M PAULUS H BULPITT K WEINBLATT M POLISSON R CLAIR PS MILNARIK P BAUDIN M LUDIN E MCAULIFFE T KAHNY MR LESSLAUER W VANDERAUWERA P
Citation: D. Furst et al., NEUTRALIZATION OF TNF BY LENERCEPT (TNFR55-IGG1 RO-45-2081) IN PATIENTS WITH RHEUMATOID-ARTHRITIS TREATED FOR 3 MONTHS - RESULTS OF AN US PHASE-II TRIAL, Arthritis and rheumatism, 39(9), 1996, pp. 1295-1295
THE TRANSMEMBRANE FORM OF TUMOR-NECROSIS-FACTOR IS THE PRIME ACTIVATING LIGAND OF THE 80 KDA TUMOR-NECROSIS-FACTOR RECEPTOR
Authors: GRELL M DOUNI E WAJANT H LOHDEN M CLAUSS M MAXEINER B GEORGOPOULOS S LESSLAUER W KOLLIAS G PFIZENMAIER K SCHEURICH P
Citation: M. Grell et al., THE TRANSMEMBRANE FORM OF TUMOR-NECROSIS-FACTOR IS THE PRIME ACTIVATING LIGAND OF THE 80 KDA TUMOR-NECROSIS-FACTOR RECEPTOR, Cell, 83(5), 1995, pp. 793-802
TRANSGENIC MICE EXPRESSING HIGH-LEVELS OF SOLUBLE TNF-R1 FUSION PROTEIN ARE PROTECTED FROM LETHAL SEPTIC SHOCK AND CEREBRAL MALARIA, AND ARE HIGHLY SENSITIVE TO LISTERIA-MONOCYTOGENES AND LEISHMANIA-MAJOR INFECTIONS
Authors: GARCIA I MIYAZAKI Y ARAKI K ARAKI M LUCAS R GRAU GE MILON G BELKAID Y MONTIXI C LESSLAUER W VASSALLI P
Citation: I. Garcia et al., TRANSGENIC MICE EXPRESSING HIGH-LEVELS OF SOLUBLE TNF-R1 FUSION PROTEIN ARE PROTECTED FROM LETHAL SEPTIC SHOCK AND CEREBRAL MALARIA, AND ARE HIGHLY SENSITIVE TO LISTERIA-MONOCYTOGENES AND LEISHMANIA-MAJOR INFECTIONS, European Journal of Immunology, 25(8), 1995, pp. 2401-2407
TUMOR-NECROSIS-FACTOR-ALPHA INDUCES ENDOTHELIAL GALACTOSYL TRANSFERASE-ACTIVITY AND VEROCYTOTOXIN RECEPTORS - ROLE OF SPECIFIC TUMOR-NECROSIS-FACTOR RECEPTORS AND PROTEIN-KINASE-C
Authors: VANDEKAR NCAJ KOOISTRA T VERMEER M LESSLAUER W MONNENS LAH VANHINSBERGH VWM
Citation: Ncaj. Vandekar et al., TUMOR-NECROSIS-FACTOR-ALPHA INDUCES ENDOTHELIAL GALACTOSYL TRANSFERASE-ACTIVITY AND VEROCYTOTOXIN RECEPTORS - ROLE OF SPECIFIC TUMOR-NECROSIS-FACTOR RECEPTORS AND PROTEIN-KINASE-C, Blood, 85(3), 1995, pp. 734-743
TNF-ALPHA POTENTLY INHIBITS PRIMITIVE HUMAN HEMATOPOIETIC PROGENITOR CELLS - INVOLVEMENT OF P55 AND P75 TNF RECEPTORS
Authors: RUSTEN LS JACOBSEN FW LESSLAUER W LOETSCHER H SMELAND EB JACOBSEN SEW
Citation: Ls. Rusten et al., TNF-ALPHA POTENTLY INHIBITS PRIMITIVE HUMAN HEMATOPOIETIC PROGENITOR CELLS - INVOLVEMENT OF P55 AND P75 TNF RECEPTORS, Journal of cellular biochemistry, 1994, pp. 21-21
PHENOTYPIC ANALYSIS OF TNFR1-DEFICIENT MICE AND CHARACTERIZATION OF TNFR1-DEFICIENT FIBROBLASTS IN-VITRO
Authors: ROTHE J MACKAY F BLUETHMANN H ZINKERNAGEL R LESSLAUER W
Citation: J. Rothe et al., PHENOTYPIC ANALYSIS OF TNFR1-DEFICIENT MICE AND CHARACTERIZATION OF TNFR1-DEFICIENT FIBROBLASTS IN-VITRO, Circulatory shock, 44(2), 1994, pp. 51-56
DIFFERENTIAL RESPONSES OF FIBROBLASTS FROM WILD-TYPE AND TNF-R55-DEFICIENT MICE TO MOUSE AND HUMAN TNF-ALPHA ACTIVATION
Authors: MACKAY F ROTHE J BLUETHMANN H LOETSCHER H LESSLAUER W
Citation: F. Mackay et al., DIFFERENTIAL RESPONSES OF FIBROBLASTS FROM WILD-TYPE AND TNF-R55-DEFICIENT MICE TO MOUSE AND HUMAN TNF-ALPHA ACTIVATION, The Journal of immunology, 153(11), 1994, pp. 5274-5284
PROTECTIVE EFFECT OF 55-KD BUT NOT 75-KD SOLUBLE TUMOR-NECROSIS-FACTOR RECEPTOR IMMUNOGLOBULIN-G FUSION PROTEINS IN AN ANIMAL-MODEL OF GRAM-NEGATIVE SEPSIS
Authors: EVANS TJ MOYES D CARPENTER A MARTIN R LOETSCHER H LESSLAUER W COHEN J
Citation: Tj. Evans et al., PROTECTIVE EFFECT OF 55-KD BUT NOT 75-KD SOLUBLE TUMOR-NECROSIS-FACTOR RECEPTOR IMMUNOGLOBULIN-G FUSION PROTEINS IN AN ANIMAL-MODEL OF GRAM-NEGATIVE SEPSIS, The Journal of experimental medicine, 180(6), 1994, pp. 2173-2179
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