Authors:
THOMAS PB
LIU ECK
WEBB ML
MUKHERJEE R
HEBBAR L
SPINALE FG
Citation: Pb. Thomas et al., EXOGENOUS EFFECTS AND ENDOGENOUS PRODUCTION OF ENDOTHELIN IN CARDIAC MYOCYTES - POTENTIAL SIGNIFICANCE IN HEART-FAILURE, American journal of physiology. Heart and circulatory physiology, 40(6), 1996, pp. 2629-2637
Authors:
WEBB ML
PATEL PS
ROSE PM
LIU ECK
STEIN PD
BARRISH J
LACH DA
STOUCH T
FISHER SM
HADJILAMBRIS O
LEE H
SKWISH S
DICKINSON EKJ
KRYSTEK SR
Citation: Ml. Webb et al., MUTATIONAL ANALYSIS OF THE ENDOTHELIN TYPE-A RECEPTOR (ET(A)) - INTERACTIONS AND MODEL OF THE SELECTIVE ET(A) ANTAGONIST EMS-182874 WITH THE PUTATIVE ET(A) RECEPTOR-BINDING CAVITY, Biochemistry, 35(8), 1996, pp. 2548-2556
Authors:
MURUGESAN N
GU ZX
LEE V
WEBB ML
LIU ECK
HERMSMEIER M
HUNT JT
Citation: N. Murugesan et al., DESIGN AND SYNTHESIS OF NONPEPTIDAL ENDOTHELIN RECEPTOR ANTAGONISTS BASED ON THE STRUCTURE OF A CYCLIC PENTAPEPTIDE, Bioorganic & medicinal chemistry letters, 5(3), 1995, pp. 253-258
Authors:
LIU ECK
PATEL PS
ROSE PM
LACH DA
FISHER SM
HADJILAMBRIS O
STEIN PD
BARRISH J
STOUCH T
NOVOTNY J
KRYSTEK SR
WEBB ML
Citation: Eck. Liu et al., INTERACTIONS AND MODAL OF THE SELECTIVE ET-A ANTAGONIST BMS-182874 WITH THE PUTATIVE ET-A RECEPTOR-BINDING CAVITY, The FASEB journal, 9(4), 1995, pp. 669-669
Authors:
WEBB ML
CHAO CC
RIZZO M
SHAPIRO RA
NEUBAUER M
LIU ECK
AVERSA CR
BRITTAIN RJ
TREIGER B
Citation: Ml. Webb et al., CLONING AND EXPRESSION OF AN ENDOTHELIN RECEPTOR SUBTYPE-B FROM HUMANPROSTATE THAT MEDIATES CONTRACTION, Molecular pharmacology, 47(4), 1995, pp. 730-737
Authors:
WEBB ML
BIRD JE
LIU ECK
ROSE PM
SERAFINO R
STEIN PD
MORELAND S
Citation: Ml. Webb et al., EMS-182874 IS A SELECTIVE, NONPEPTIDE ENDOTHELIN ET(A) RECEPTOR ANTAGONIST, The Journal of pharmacology and experimental therapeutics, 272(3), 1995, pp. 1124-1134
Authors:
STEIN PD
FLOYD DM
BISAHA S
DICKEY J
GIROTRA RN
GOUGOUTAS JZ
KOZLOWSKI M
LEE VG
LIU ECK
MALLEY MF
MCMULLEN D
MITCHELL C
MORELAND S
MURUGESAN N
SERAFINO R
WEBB ML
ZHANG R
HUNT JT
Citation: Pd. Stein et al., DISCOVERY AND STRUCTURE-ACTIVITY-RELATIONSHIPS OF SULFONAMIDE ETA-SELECTIVE ANTAGONISTS, Journal of medicinal chemistry, 38(8), 1995, pp. 1344-1354
Authors:
ROSE PM
KRYSTEK SR
PATEL PS
LIU ECK
LYNCH JS
LACH DA
FISHER SM
WEBB ML
Citation: Pm. Rose et al., ASPARTATE MUTATION DISTINGUISHES ET(A) BUT NOT ET(B) RECEPTOR SUBTYPE-SELECTIVE LIGAND-BINDING WHILE ABOLISHING PHOSPHOLIPASE-C ACTIVATION IN BOTH RECEPTORS, FEBS letters, 361(2-3), 1995, pp. 243-249
Authors:
LIU ECK
MONSHIZADEGAN H
BRITTAIN RJ
ROSE PM
WEBB ML
Citation: Eck. Liu et al., EFFECTS OF BMS-182874 ON BINDING AND SIGNAL-TRANSDUCTION AT HUMAN ANDRAT ENDOTHELIN (ET) RECEPTORS - CHARACTERIZATION OF A SELECTIVE, NONPEPTIDIC ET(A) RECEPTOR ANTAGONIST, The FASEB journal, 8(4), 1994, pp. 10000102-10000102
Authors:
SARGENT CA
LIU ECK
CHAO CC
MONSHIZADEGAN H
WEBB ML
GROVER GJ
Citation: Ca. Sargent et al., ROLE OF ENDOTHELIN RECEPTOR SUBTYPE-B (ET-B) IN MYOCARDIAL-ISCHEMIA (VOL 55, PG 1833, 1994), Life sciences, 56(5), 1994, pp. 361-361
Authors:
STEIN PD
HUNT JT
FLOYD DM
MORELAND S
DICKINSON KEJ
MITCHELL C
LIU ECK
WEBB ML
MURUGESAN N
DICKEY J
MCMULLEN D
ZHANG RG
LEE VG
SERAFINO R
DELANEY C
SCHAEFFER TR
KOZLOWSKI M
Citation: Pd. Stein et al., THE DISCOVERY OF SULFONAMIDE ENDOTHELIN ANTAGONISTS AND THE DEVELOPMENT OF THE ORALLY-ACTIVE ET(A)ANTAGONIST ,4-DIMETHYL-5-ISOXAZOLYL)-1-NAPHTHALENESULFONAMIDE, Journal of medicinal chemistry, 37(3), 1994, pp. 329-331
Authors:
KRYSTEK SR
PATEL PS
ROSE PM
FISHER SM
KIENZLE BK
LACH DA
LIU ECK
LYNCH JS
NOVOTNY J
WEBB ML
Citation: Sr. Krystek et al., MUTATION OF PEPTIDE BINDING-SITE IN TRANSMEMBRANE REGION OF A G-PROTEIN-COUPLED RECEPTOR ACCOUNTS FOR ENDOTHELIN RECEPTOR SUBTYPE SELECTIVITY, The Journal of biological chemistry, 269(17), 1994, pp. 12383-12386
Authors:
HUNT JT
LEE VG
LIU ECK
MORELAND S
MCMULLEN D
WEBB ML
BOLGAR M
Citation: Jt. Hunt et al., CONTROL OF PEPTIDE DISULFIDE REGIOISOMER FORMATION BY MIXED CYSTEINE PENICILLAMINE BRIDGES - APPLICATION TO ENDOTHELIN-1, International journal of peptide & protein research, 42(3), 1993, pp. 249-258
Authors:
LIU ECK
MONSHIZADEGAN H
CHAO CC
LYNCH J
FISHER SM
ROSE PM
WEBB ML
Citation: Eck. Liu et al., BINDING OF I-125 ENDOTHELIN-1 AND I-125 ENDOTHELIN-3 IN RABBIT SAPHENOUS-VEIN - EVIDENCE FOR AN ATYPICAL ET BINDING-COMPONENT, Journal of cardiovascular pharmacology, 22, 1993, pp. 190000132-190000135