AAAAAA

   
Results: 1-12 |
Results: 12
L-374,087, AN EFFICACIOUS, ORALLY BIOAVAILABLE, PYRIDINONE ACETAMIDE THROMBIN INHIBITOR
Authors: SANDERSON PEJ CUTRONA KJ DORSEY BD DYER DL MCDONOUGH CM NAYLOROLSEN AM CHEN IW CHEN ZG COOK JJ GARDELL SJ KRUEGER JA LEWIS SD LIN JH LUCAS BJ LYLE EA LYNCH JJ STRANIERI MT VASTAG K SHAFER JA VACCA JP
Citation: Pej. Sanderson et al., L-374,087, AN EFFICACIOUS, ORALLY BIOAVAILABLE, PYRIDINONE ACETAMIDE THROMBIN INHIBITOR, Bioorganic & medicinal chemistry letters, 8(7), 1998, pp. 817-822
DESIGN OF NOVEL, POTENT, NONCOVALENT INHIBITORS OF THROMBIN WITH NONBASIC P-1 SUBSTRUCTURES - RAPID STRUCTURE-ACTIVITY STUDIES BY SOLID-PHASE SYNTHESIS
Authors: LUMMA WC WITHERUP KM TUCKER TJ BRADY SF SISKO JT NAYLOROLSEN AM LEWIS SD LUCAS BJ VACCA JP
Citation: Wc. Lumma et al., DESIGN OF NOVEL, POTENT, NONCOVALENT INHIBITORS OF THROMBIN WITH NONBASIC P-1 SUBSTRUCTURES - RAPID STRUCTURE-ACTIVITY STUDIES BY SOLID-PHASE SYNTHESIS, Journal of medicinal chemistry, 41(7), 1998, pp. 1011-1013
DISCOVERY AND DEVELOPMENT OF THE NOVEL POTENT ORALLY-ACTIVE THROMBIN INHIBITOR N-(9-HYDROXY-9-FLUORENECARBOXY)PROLYL TRANS-4-AMINOCYCLOHEXYLMETHYL AMIDE (L-372,460) - COAPPLICATION OF STRUCTURE-BASED DESIGN AND RAPID MULTIPLE ANALOG SYNTHESIS ON SOLID SUPPORT
Authors: BRADY SF STAUFFER KJ LUMMA WC SMITH GM RAMJIT HG LEWIS SD LUCAS BJ GARDELL SJ LYLE EA APPLEBY SD COOK JJ HOLAHAN MA STRANIERI MT LYNCH JJ LIN JH CHEN IW VASTAG K NAYLOROLSEN AM VACCA JP
Citation: Sf. Brady et al., DISCOVERY AND DEVELOPMENT OF THE NOVEL POTENT ORALLY-ACTIVE THROMBIN INHIBITOR N-(9-HYDROXY-9-FLUORENECARBOXY)PROLYL TRANS-4-AMINOCYCLOHEXYLMETHYL AMIDE (L-372,460) - COAPPLICATION OF STRUCTURE-BASED DESIGN AND RAPID MULTIPLE ANALOG SYNTHESIS ON SOLID SUPPORT, Journal of medicinal chemistry, 41(3), 1998, pp. 401-406
EFFICACIOUS, ORALLY BIOAVAILABLE THROMBIN INHIBITORS BASED ON 3-AMINOPYRIDINONE OR 3-AMINOPYRAZINONE ACETAMIDE PEPTIDOMIMETIC TEMPLATES
Authors: SANDERSON PEJ LYLE TA CUTRONA KJ DYER DL DORSEY BD MCDONOUGH CM NAYLOROLSEN AM CHEN IW CHEN ZG COOK JJ COOPER CM GARDELL SJ HARE TR KRUEGER JA LEWIS SD LIN JH LUCAS BJ LYLE EA LYNCH JJ STRANIERI MT VASTAG K YAN YW SHAFER JA VACCA JP
Citation: Pej. Sanderson et al., EFFICACIOUS, ORALLY BIOAVAILABLE THROMBIN INHIBITORS BASED ON 3-AMINOPYRIDINONE OR 3-AMINOPYRAZINONE ACETAMIDE PEPTIDOMIMETIC TEMPLATES, Journal of medicinal chemistry, 41(23), 1998, pp. 4466-4474
DESIGN AND SYNTHESIS OF A SERIES OF POTENT AND ORALLY BIOAVAILABLE NONCOVALENT THROMBIN INHIBITORS THAT UTILIZE NONBASIC GROUPS IN THE P1 POSITION
Authors: TUCKER TJ BRADY SF LUMMA WC LEWIS SD GARDELL SJ NAYLOROLSEN AM YAN YW SISKO JT STAUFFER KJ LUCAS BJ LYNCH JJ COOK JJ STRANIERI MT HOLAHAN MA LYLE EA BASKIN EP CHEN IW DANCHECK KB KRUEGER JA COOPER CM VACCA JP
Citation: Tj. Tucker et al., DESIGN AND SYNTHESIS OF A SERIES OF POTENT AND ORALLY BIOAVAILABLE NONCOVALENT THROMBIN INHIBITORS THAT UTILIZE NONBASIC GROUPS IN THE P1 POSITION, Journal of medicinal chemistry, 41(17), 1998, pp. 3210-3219
CHARACTERIZATION OF THE 2-STEP PATHWAY FOR INHIBITION OF THROMBIN BY ALPHA-KETOAMIDE TRANSITION-STATE ANALOGS
Authors: LEWIS SD LUCAS BJ BRADY SF SISKO JT CUTRONA KJ SANDERSON PEJ FREIDINGER RM MAO SS GARDELL SJ SHAFER JA
Citation: Sd. Lewis et al., CHARACTERIZATION OF THE 2-STEP PATHWAY FOR INHIBITION OF THROMBIN BY ALPHA-KETOAMIDE TRANSITION-STATE ANALOGS, The Journal of biological chemistry, 273(9), 1998, pp. 4843-4854
L-373,890, AN ACHIRAL, NONCOVALENT, SUBNANOMOLAR THROMBIN INHIBITOR
Authors: SANDERSON PEJ DYER DL NAYLOROLSEN AM VACCA JP GARDELL SJ LEWIS SD LUCAS BJ LYLE EA LYNCH JJ MULICHAK AM
Citation: Pej. Sanderson et al., L-373,890, AN ACHIRAL, NONCOVALENT, SUBNANOMOLAR THROMBIN INHIBITOR, Bioorganic & medicinal chemistry letters, 7(12), 1997, pp. 1497-1500
SYNTHESIS OF A SERIES OF POTENT AND ORALLY BIOAVAILABLE THROMBIN INHIBITORS THAT UTILIZE 3,3-DISUBSTITUTED PROPIONIC-ACID DERIVATIVES IN THE P-3 POSITION
Authors: TUCKER TJ LUMMA WC LEWIS SD GARDELL SJ LUCAS BJ SISKO JT LYNCH JJ LYLE EA BASKIN EP WOLTMANN RF APPLEBY SD
Citation: Tj. Tucker et al., SYNTHESIS OF A SERIES OF POTENT AND ORALLY BIOAVAILABLE THROMBIN INHIBITORS THAT UTILIZE 3,3-DISUBSTITUTED PROPIONIC-ACID DERIVATIVES IN THE P-3 POSITION, Journal of medicinal chemistry, 40(22), 1997, pp. 3687-3693
POTENT NONCOVALENT THROMBIN INHIBITORS THAT UTILIZE THE UNIQUE AMINO-ACID D-DICYCLOHEXYLALANINE IN THE P3 POSITION - IMPLICATIONS ON ORAL BIOAVAILABILITY AND ANTITHROMBOTIC EFFICACY
Authors: TUCKER TJ LUMMA WC LEWIS SD GARDELL SJ LUCAS BJ BASKIN EP WOLTMANN R LYNCH JJ LYLE EA APPLEBY SD CHEN IW DANCHECK KB VACCA JP
Citation: Tj. Tucker et al., POTENT NONCOVALENT THROMBIN INHIBITORS THAT UTILIZE THE UNIQUE AMINO-ACID D-DICYCLOHEXYLALANINE IN THE P3 POSITION - IMPLICATIONS ON ORAL BIOAVAILABILITY AND ANTITHROMBOTIC EFFICACY, Journal of medicinal chemistry, 40(11), 1997, pp. 1565-1569
THE 2ND EPISTEMIC WAY REVISITED - REPLY TO PROFESSOR BEARD 'PROFESSORLUCAS ON OMNISCIENCE'
Authors: LUCAS BJ
Citation: Bj. Lucas, THE 2ND EPISTEMIC WAY REVISITED - REPLY TO PROFESSOR BEARD 'PROFESSORLUCAS ON OMNISCIENCE', International journal for philosophy of religion, 42(3), 1997, pp. 143-162
ONTOLOGICAL ARGUMENTS AND BELIEF IN GOD - OPPY,G
Authors: LUCAS BJ
Citation: Bj. Lucas, ONTOLOGICAL ARGUMENTS AND BELIEF IN GOD - OPPY,G, International journal for philosophy of religion, 41(3), 1997, pp. 181-183
GOD, SUFFERING AND SOLIPSISM - DORE,C
Authors: LUCAS BJ
Citation: Bj. Lucas, GOD, SUFFERING AND SOLIPSISM - DORE,C, International journal for philosophy of religion, 34(1), 1993, pp. 60-61
Risultati: 1-12 |