Authors:
TURNER SR
STROHBACH JW
TOMMASI RA
ARISTOFF PA
JOHNSON PD
SKULNICK HI
DOLAK LA
SEEST EP
TOMICH PK
BOHANAN MJ
HORNG MM
LYNN JC
CHONG KT
HINSHAW RR
WATENPAUGH KD
JANAKIRAMAN MN
THAISRIVONGS S
Citation: Sr. Turner et al., TIPRANAVIR (PNU-140690) - A POTENT, ORALLY BIOAVAILABLE NONPEPTIDIC HIV PROTEASE INHIBITOR OF THE 5,6-DIHYDRO-4-HYDROXY-2-PYRONE SULFONAMIDE CLASS, Journal of medicinal chemistry, 41(18), 1998, pp. 3467-3476
Authors:
SCHWARTZ TM
BUNDY GL
STROHBACH JW
THAISRIVONGS S
JOHNSON PD
SKULNICK HI
TOMICH PK
LYNN JC
CHONG KT
HINSHAW RR
RAUB TJ
PADBURY GE
TOTH LN
Citation: Tm. Schwartz et al., SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF SULFONE SUBSTITUTED HIV PROTEASE INHIBITORS, Bioorganic & medicinal chemistry letters, 7(4), 1997, pp. 399-402
Citation: De. Schmidt et al., ATTENUATION OF 1-METHYL-4-PHENYLPYRIDINIUM (MPP-NIGRA CULTURES() NEUROTOXICITY BY DEPRENYL IN ORGANOTYPIC CANINE SUBSTANTIA), Journal of neural transmission, 104(8-9), 1997, pp. 875-885
Authors:
SKULNICK HI
JOHNSON PD
ARISTOFF PA
MORRIS JK
LOVASZ KD
HOWE WJ
WATENPAUGH KD
JANAKIRAMAN MN
ANDERSON DJ
REISCHER RJ
SCHWARTZ TM
BANITT LS
TOMICH PK
LYNN JC
HORNG MM
CHONG KT
HINSHAW RR
DOLAK LA
SEEST EP
SCHWENDE FJ
RUSH BD
HOWARD GM
TOTH LN
WILKINSON KR
KAKUK TJ
JOHNSON CW
COLE SL
ZAYA RM
ZIPP GL
POSSERT PL
DALGA RJ
ZHONG WZ
WILLIAMS MG
ROMINES KR
Citation: Hi. Skulnick et al., STRUCTURE-BASED DESIGN OF NONPEPTIDIC HIV PROTEASE INHIBITORS - THE SULFONAMIDE-SUBSTITUTED CYCLOOCTYLPYRANONES, Journal of medicinal chemistry, 40(7), 1997, pp. 1149-1164
Authors:
THAISRIVONGS S
ROMERO DL
TOMMASI RA
JANAKIRAMAN MN
STROHBACH JW
TURNER SR
BILES C
MORGE RR
JOHNSON PD
ARISTOFF PA
TOMICH PK
LYNN JC
HORNG MM
CHONG KT
HINSHAW RR
HOWE WJ
FINZEL BC
WATENPAUGH KD
Citation: S. Thaisrivongs et al., STRUCTURE-BASED DESIGN OF HIV PROTEASE INHIBITORS - 5,6-DIHYDRO-4-HYDROXY-2-PYRONES AS EFFECTIVE, NONPEPTIDIC INHIBITORS, Journal of medicinal chemistry, 39(23), 1996, pp. 4630-4642
Authors:
THAISRIVONGS S
SKULNICK HI
TURNER SR
STROHBACH JW
TOMMASI RA
JOHNSON PD
ARISTOFF PA
JUDGE TM
GAMMILL RB
MORRIS JK
ROMINES KR
CHRUSCIEL RA
HINSHAW RR
CHONG KT
TARPLEY WG
POPPE SM
SLADE DE
LYNN JC
HORNG MM
TOMICH PK
SEEST EP
DOLAK LA
HOWE WJ
HOWARD GM
SCHWENDE FJ
TOTH LN
PADBURY GE
WILSON GJ
SHIOU LH
ZIPP GL
WILKINSON KF
RUSH BD
RUWART MJ
KOEPLINGER KA
ZHAO ZY
COLE S
ZAYA RM
KAKUK TJ
JANAKIRAMAN MN
WATENPAUGH KD
Citation: S. Thaisrivongs et al., STRUCTURE-BASED DESIGN OF HIV PROTEASE INHIBITORS - SULFONAMIDE-CONTAINING 5,6-DIHYDRO-4-HYDROXY-2-PYRONES AS NONPEPTIDIC INHIBITORS, Journal of medicinal chemistry, 39(22), 1996, pp. 4349-4353
Authors:
SKULNICK HI
JOHNSON PD
HOWE WJ
TOMICH PK
CHONG KT
WATENPAUGH KD
JANAKIRAMAN MN
DOLAK LA
MCGRATH JP
LYNN JC
HORNG MM
HINSHAW RR
ZIPP GL
RUWART MJ
SCHWENDE FJ
ZHONG WZ
PADBURY GE
DALGA RJ
SHIOU LH
POSSERT PL
RUSH BD
WILKINSON KF
HOWARD GM
TOTH LN
WILLIAMS MG
KAKUK TJ
COLE SL
ZAYA RM
LOVASZ KD
MORRIS JK
ROMINES KR
THAISRIVONGS S
ARISTOFF PA
Citation: Hi. Skulnick et al., STRUCTURE-BASED DESIGN OF SULFONAMIDE-SUBSTITUTED NONPEPTIDIC HIV PROTEASE INHIBITORS, Journal of medicinal chemistry, 38(26), 1995, pp. 4968-4971
Authors:
ROMINES KR
WATENPAUGH KD
HOWE WJ
TOMICH PK
LOVASZ KD
MORRIS JK
JANAKIRAMAN MN
LYNN JC
HORNG MM
CHONG KT
HINSHAW RR
DOLAK LA
Citation: Kr. Romines et al., STRUCTURE-BASED DESIGN OF NONPEPTIDIC HIV PROTEASE INHIBITORS FROM A CYCLOOCTYLPYRANONE LEAD STRUCTURE, Journal of medicinal chemistry, 38(22), 1995, pp. 4463-4473
Authors:
THAISRIVONGS S
WATENPAUGH KD
HOWE WJ
TOMICH PK
DOLAK LA
CHONG KT
TOMICH CSC
TOMASSELLI AG
TURNER SR
STROHBACH JW
MULICHAK AM
JANAKIRAMAN MN
MOON JB
LYNN JC
HORNG MM
HINSHAW RR
CURRY KA
ROTHROCK DJ
Citation: S. Thaisrivongs et al., STRUCTURE-BASED DESIGN OF NOVEL HIV PROTEASE INHIBITORS - CARBOXAMIDE-CONTAINING 4-HYDROXYCOUMARINS AND 4-HYDROXY-2-PYRONES AS POTENT NONPEPTIDIC INHIBITORS, Journal of medicinal chemistry, 38(18), 1995, pp. 3624-3637
Authors:
ROMINES KR
WATENPAUGH KD
TOMICH PK
HOWE WJ
MORRIS JK
LOVASZ KD
MULICHAK AM
FINZEL BC
LYNN JC
HORNG MM
SCHWENDE FJ
RUWART MJ
ZIPP GL
CHONG KT
DOLAK LA
TOTH LN
HOWARD GM
RUSH BD
WILKINSON KF
POSSERT PL
DALGA RJ
HINSHAW RR
Citation: Kr. Romines et al., USE OF MEDIUM-SIZED CYCLOALKYL RINGS TO ENHANCE SECONDARY BINDING - DISCOVERY OF A NEW CLASS OF HUMAN-IMMUNODEFICIENCY-VIRUS (HIV) PROTEASEINHIBITORS, Journal of medicinal chemistry, 38(11), 1995, pp. 1884-1891
Authors:
THAISRIVONGS S
TOMICH PK
WATENPAUGH KD
CHONG KT
HOWE WJ
YANG CP
STROHBACH JW
TURNER SR
MCGRATH JP
BOHANON MJ
LYNN JC
MULICHAK AM
SPINELLI PA
HINSHAW RR
PAGANO PJ
MOON JB
RUWART MJ
WILKINSON KF
RUSH BD
ZIPP GL
DALGA RJ
SCHWENDE FJ
HOWARD GM
PADBURY GE
TOTH LN
ZHAO ZY
KOEPLINGER KA
KAKUK TJ
COLE SL
ZAYA RM
PIPER RC
JEFFREY P
Citation: S. Thaisrivongs et al., STRUCTURE-BASED DESIGN OF HIV PROTEASE INHIBITORS - 4-HYDROXYCOUMARINS AND 4-HYDROXY-2-PYRONES AS NONPEPTIDIC INHIBITORS, Journal of medicinal chemistry, 37(20), 1994, pp. 3200-3204
Authors:
LYNN JC
TOMICH PK
BOHANON MJ
HORNG MM
SEEST EP
DOLAK LA
LI GP
CIALDELLA JI
Citation: Jc. Lynn et al., DISCOVERY OF INHIBITORS OF HIV PROTEASE IN NATURAL PRODUCT FERMENTATION EXTRACTS USING A HIGH-VOLUME FLUORESCENTLY BASED ASSAY, Journal of cellular biochemistry, 1993, pp. 17-17