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Results: 1-8 |
Results: 8
Synthesis and SAR of benzamidine factor Xa inhibitors containing a vicinally-substituted heterocyclic core
Authors: Fevig, JM Pinto, DJ Han, Q Quan, ML Pruitt, JR Jacobson, IC Galemmo, RA Wang, SA Orwat, MJ Bostrom, LL Knabb, RM Wong, PC Lam, PYS Wexler, RR
Citation: Jm. Fevig et al., Synthesis and SAR of benzamidine factor Xa inhibitors containing a vicinally-substituted heterocyclic core, BIOORG MED, 11(5), 2001, pp. 641-645
Copper-catalyzed general C-N and C-O bond cross-coupling with arylboronic acid
Authors: Lam, PYS Vincent, G Clark, CG Deudon, S Jadhav, PK
Citation: Pys. Lam et al., Copper-catalyzed general C-N and C-O bond cross-coupling with arylboronic acid, TETRAHEDR L, 42(20), 2001, pp. 3415-3418
alpha-nitrogen activating effect in the room temperature copper-promoted N-arylation of heteroarylcarboxamides with phenyl siloxane or p-toluylboronic acid
Authors: Lam, PYS Deudon, S Hauptman, E Clark, CG
Citation: Pys. Lam et al., alpha-nitrogen activating effect in the room temperature copper-promoted N-arylation of heteroarylcarboxamides with phenyl siloxane or p-toluylboronic acid, TETRAHEDR L, 42(13), 2001, pp. 2427-2429
Discovery of 1-[3-(aminomethyl)phenyl]-N-[3-fluoro-2 '- (methylsulfonyl)-[1,1 '-biphenyl]-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide (DPC423), a highly potent, selective, and orally bioavailable inhibitor of blood coagulation factor Xa
Authors: Pinto, DJP Orwat, MJ Wang, SG Fevig, JM Quan, ML Amparo, E Cacciola, J Rossi, KA Alexander, RS Smallwood, AM Luettgen, JM Liang, L Aungst, BJ Wright, MR Knabb, RM Wong, PC Wexler, RR Lam, PYS
Citation: Djp. Pinto et al., Discovery of 1-[3-(aminomethyl)phenyl]-N-[3-fluoro-2 '- (methylsulfonyl)-[1,1 '-biphenyl]-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide (DPC423), a highly potent, selective, and orally bioavailable inhibitor of blood coagulation factor Xa, J MED CHEM, 44(4), 2001, pp. 566-578
Copper promoted aryl/saturated heterocyclic C-N bond cross-coupling with arylboronic acid and arylstannane
Authors: Lam, PYS Clark, CG Saubern, S Adams, J Averill, KM Chan, DMT Combs, A
Citation: Pys. Lam et al., Copper promoted aryl/saturated heterocyclic C-N bond cross-coupling with arylboronic acid and arylstannane, SYNLETT, (5), 2000, pp. 674-676
Copper-promoted C-N bond cross-coupling with hypervalent aryl siloxanes and room-temperature N-arylation with aryl iodide
Authors: Lam, PYS Deudon, S Averill, KM Li, RH He, MY DeShong, P Clark, CG
Citation: Pys. Lam et al., Copper-promoted C-N bond cross-coupling with hypervalent aryl siloxanes and room-temperature N-arylation with aryl iodide, J AM CHEM S, 122(31), 2000, pp. 7600-7601
Solid supported aryl/heteroaryl C-N cross-coupling reactions.
Authors: Combs, AP Saubern, S Rafalski, M Lam, PYS
Citation: Ap. Combs et al., Solid supported aryl/heteroaryl C-N cross-coupling reactions., TETRAHEDR L, 40(9), 1999, pp. 1623-1626
Stereoisomers of cyclic urea HIV-1 protease inhibitors: Synthesis and binding affinities
Authors: Kaltenbach, RF Nugiel, DA Lam, PYS Klabe, RM Seitz, SP
Citation: Rf. Kaltenbach et al., Stereoisomers of cyclic urea HIV-1 protease inhibitors: Synthesis and binding affinities, J MED CHEM, 41(25), 1998, pp. 5113-5117
Risultati: 1-8 |