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Results: 1-25/37
Authors:
Small, KM
Rathz, DA
Liggett, SB
Citation: Km. Small et al., Identification of adrenergic receptor polymorphisms, METH ENZYM, 343, 2002, pp. 459-475
Authors:
Small, KM
Liggett, SB
Citation: Km. Small et Sb. Liggett, Identification and functional characterization of alpha(2)-adrenoceptor polymorphisms, TRENDS PHAR, 22(9), 2001, pp. 471-477
Authors:
Liggett, SB
Citation: Sb. Liggett, Pharmacogenetic applications of the Human Genome Project, NAT MED, 7(3), 2001, pp. 281-283
Authors:
McGraw, DW
Fukuda, N
James, PF
Forbes, SL
Woo, AL
Lingrel, JB
Witte, DP
Matthay, MA
Liggett, SB
Citation: Dw. Mcgraw et al., Targeted transgenic expression of beta(2)-adrenergic receptors to type II cells increases alveolar fluid clearance, AM J P-LUNG, 281(4), 2001, pp. L895-L903
Authors:
Israel, E
Drazen, JM
Liggett, SB
Boushey, HA
Cherniack, RM
Chinchilli, VM
Cooper, DM
Fahy, JV
Fish, JE
Ford, JG
Kraft, M
Kunselman, S
Lazarus, SC
Lemanske, RF
Martin, RJ
McLean, DE
Peters, SP
Silverman, EK
Sorkness, CA
Szefler, SJ
Weiss, ST
Yandava, CN
Citation: E. Israel et al., Effect of polymorphism of the beta(2)-adrenergic receptor on response to regular use of albuterol in asthma, INT A AL IM, 124(1-3), 2001, pp. 183-186
Authors:
Liggett, SB
Citation: Sb. Liggett, beta-adrenergic receptors in the failing heart: the good, the bad, and theunknown, J CLIN INV, 107(8), 2001, pp. 947-948
Authors:
Small, KM
Brown, KM
Forbes, SL
Liggett, SB
Citation: Km. Small et al., Polymorphic deletion of three intracellular acidic residues of the alpha(2B)-adrenergic receptor decreases G protein-coupled receptor kinase-mediatedphosphorylation and desensitization, J BIOL CHEM, 276(7), 2001, pp. 4917-4922
Authors:
Small, KM
Brown, KM
Forbes, SL
Liggett, SB
Citation: Km. Small et al., Modification of the beta(2)-adrenergic receptor to engineer a receptor-effector complex for gene therapy, J BIOL CHEM, 276(34), 2001, pp. 31596-31601
Authors:
Green, SA
Rathz, DA
Schuster, AJ
Liggett, SB
Citation: Sa. Green et al., The Ile164 beta(2)-adrenoceptor polymorphism alters salmeterol exosite binding and conventional agonist coupling to G(s), EUR J PHARM, 421(3), 2001, pp. 141-147
Authors:
Dash, R
Kadambi, VJ
Schmidt, AG
Tepe, NM
Biniakiewicz, D
Gerst, MJ
Canning, AM
Abraham, WT
Hoit, BD
Liggett, SB
Lorenz, JN
Dorn, GW
Kranias, EG
Citation: R. Dash et al., Interactions between phospholamban and beta-adrenergic drive may lead to cardiomyopathy and early mortality, CIRCULATION, 103(6), 2001, pp. 889-896
Authors:
Liang, M
Freedman, NJ
Theiss, CT
Liggett, SB
Citation: M. Liang et al., Serine 232 of the alpha(2A)-adrenergic receptor is a protein kinase C-sensitive effector coupling switch, BIOCHEM, 40(49), 2001, pp. 15031-15037
Authors:
Tepe, NM
Liggett, SB
Citation: Nm. Tepe et Sb. Liggett, Functional receptor coupling to G(i) is mechanism of agonist-promoted desensitization of the beta(2)-adrenergic receptor, J RECEPT SI, 20(1), 2000, pp. 75-85
Authors:
Israel, E
Drazen, JM
Liggett, SB
Boushey, HA
Cherniack, RM
Chinchilli, VM
Cooper, DM
Fahy, JV
Fish, JE
Ford, JG
Kraft, M
Kunselman, S
Lazarus, SC
Lemanske, RF
Martin, RJ
McLean, DE
Peters, SP
Silverman, EK
Sorkness, CA
Szefler, SJ
Weiss, ST
Yandava, CN
Citation: E. Israel et al., The effect of polymorphisms of the beta(2)-adrenergic receptor on the response to regular use of albuterol in asthma, AM J R CRIT, 162(1), 2000, pp. 75-80
Authors:
Liggett, SB
Citation: Sb. Liggett, beta(2)-Adrenergic receptor pharmacogenetics, AM J R CRIT, 161(3), 2000, pp. S197-S201
Authors:
McGraw, DW
Forbes, SL
Mak, JCW
Witte, DP
Carrigan, PE
Leikauf, GD
Liggett, SB
Citation: Dw. Mcgraw et al., Transgenic overexpression of beta(2)-adrenergic receptors in airway epithelial cells decreases bronchoconstriction, AM J P-LUNG, 279(2), 2000, pp. L379-L389
Authors:
Yan, L
Galinsky, RE
Bernstein, JA
Liggett, SB
Weinshilboum, RM
Citation: L. Yan et al., Histamine N-methyltransferase pharmacogenetics: association of a common functional polymorphism with asthma, PHARMACOGEN, 10(3), 2000, pp. 261-266
Authors:
Liggett, SB
Citation: Sb. Liggett, The pharmacogenetics of beta(2)-adrenergic receptors: Relevance to asthma, J ALLERG CL, 105(2), 2000, pp. S487-S492
Authors:
Liggett, SB
Citation: Sb. Liggett, Pharmacogenetics of beta-1-beta- and 2-adrenergic receptors, PHARMACOL, 61(3), 2000, pp. 167-173
Authors:
Drysdale, CM
McGraw, DW
Stack, CB
Stephens, JC
Judson, RS
Nandabalan, K
Arnold, K
Ruano, G
Liggett, SB
Citation: Cm. Drysdale et al., Complex promoter and coding region beta(2)-adrenergic receptor haplotypes alter receptor expression and predict in vivo responsiveness, P NAS US, 97(19), 2000, pp. 10483-10488
Authors:
Dorn, GW
Tepe, NM
Wu, GY
Yatani, A
Liggett, SB
Citation: Gw. Dorn et al., Mechanisms of impaired beta-adrenergic receptor signaling in G(alpha q)-mediated cardiac hypertrophy and ventricular dysfunction, MOLEC PHARM, 57(2), 2000, pp. 278-287
Authors:
Small, KM
Forbes, SL
Brown, KM
Liggett, SB
Citation: Km. Small et al., An Asn to Lys polymorphism in the third intracellular loop of the human alpha(2A)-adrenergic receptor imparts enhanced agonist-promoted G(i) coupling, J BIOL CHEM, 275(49), 2000, pp. 38518-38523
Authors:
Jewell-Motz, EA
Small, KM
Theiss, CT
Liggett, SB
Citation: Ea. Jewell-motz et al., alpha(2A)/alpha(2C)-adrenergic receptor third loop chimera show that agonist interaction with receptor subtype backbone establishes G protein-coupledreceptor kinase phosphorylation, J BIOL CHEM, 275(37), 2000, pp. 28989-28993
Authors:
Small, KM
Forbes, SL
Rahman, FF
Bridges, KM
Liggett, SB
Citation: Km. Small et al., A four amino acid deletion polymorphism in the third intracellular loop ofthe human alpha(2C)-adrenergic receptor confers impaired coupling to multiple effectors, J BIOL CHEM, 275(30), 2000, pp. 23059-23064
Authors:
Wagoner, LE
Craft, LL
Singh, B
Suresh, DP
Zengel, PW
McGuire, N
Abraham, WT
Chenier, TC
Dorn, GW
Liggett, SB
Citation: Le. Wagoner et al., Polymorphisms of the beta(2)-adrenergic receptor determine exercise capacity in patients with heart failure, CIRCUL RES, 86(8), 2000, pp. 834-840
Authors:
Liggett, SB
Tepe, NM
Lorenz, JN
Canning, AM
Jantz, TD
Mitarai, S
Yatani, A
Dorn, GW
Citation: Sb. Liggett et al., Early and delayed consequences of beta(2)-adrenergic receptor overexpression in mouse hearts - Critical role for expression level, CIRCULATION, 101(14), 2000, pp. 1707-1714