Authors:
Engelholm, LH
Nielsen, BS
Netzel-Arnett, S
Solberg, H
Chen, XD
Garcia, JML
Lopez-Otin, C
Young, MF
Birkedal-Hansen, H
Dano, K
Lund, LR
Behrendt, N
Bugge, TH
Citation: Lh. Engelholm et al., The urokinase plasminogen activator receptor-associated Protein/Endo180 iscoexpressed with its interaction partners urokinase plasminogen activator receptor and matrix metalloprotease-13 during osteogenesis, LAB INV, 81(10), 2001, pp. 1403-1414
Authors:
Cal, S
Arguelles, JM
Fernandez, PL
Lopez-Otin, C
Citation: S. Cal et al., Identification, characterization, and intracellular processing of ADAM-TS12, a novel human disintegrin with a complex structural organization involving multiple thrombospondin-1 repeats, J BIOL CHEM, 276(21), 2001, pp. 17932-17940
Authors:
Balbin, M
Fueyo, A
Knauper, V
Lopez, JM
Alvarez, J
Sanchez, LM
Quesada, V
Bordallo, J
Murphy, G
Lopez-Otin, C
Citation: M. Balbin et al., Identification and enzymatic characterization of two diverging murine counterparts of human interstitial collagenase (MMP-1) expressed at sites of embryo implantation, J BIOL CHEM, 276(13), 2001, pp. 10253-10262
Authors:
Nielsen, BS
Rank, F
Lopez, JM
Balbin, M
Vizoso, F
Lund, LR
Dano, K
Lopez-Otin, C
Citation: Bs. Nielsen et al., Collagenase-3 expression in breast myofibroblasts as a molecular marker oftransition of ductal carcinoma in situ lesions to invasive ductal carcinomas, CANCER RES, 61(19), 2001, pp. 7091-7100
Authors:
Cal, S
Freije, JMP
Lopez, JM
Takada, Y
Lopez-Otin, C
Citation: S. Cal et al., ADAM 23/MDC3, a human disintegrin that promotes cell adhesion via interaction with the alpha v beta 3 integrin through an RGD-independent mechanism, MOL BIOL CE, 11(4), 2000, pp. 1457-1469
Authors:
Ala-aho, R
Johansson, N
Grenman, R
Fusenig, NE
Lopez-Otin, C
Kahari, VM
Citation: R. Ala-aho et al., Inhibition of collagenase-3 (MMP-13) expression in transformed human keratinocytes by interferon-gamma is associated with activation of extracellularsignal-regulated kinase-1,2 and STAT1, ONCOGENE, 19(2), 2000, pp. 248-257
Authors:
Johansson, N
Ala-Aho, R
Uitto, VJ
Grenman, R
Fusenig, NE
Lopez-Otin, C
Kahari, VM
Citation: N. Johansson et al., Expression of collagenase-3 (MMP-13) and collagenase-1 (MMP-1) by transformed keratinocytes is dependent on the activity of p38 mitogen-activated protein kinase, J CELL SCI, 113(2), 2000, pp. 227-235
Authors:
Llano, E
Pendas, AM
Aza-Blanc, P
Kornberg, TB
Lopez-Otin, C
Citation: E. Llano et al., Dm1-MMP, a matrix metalloproteinase from Drosophila with a potential role in extracellular matrix remodeling during neural development, J BIOL CHEM, 275(46), 2000, pp. 35978-35985
Authors:
Stracke, JO
Hutton, M
Stewart, M
Pendas, AM
Smith, B
Lopez-Otin, C
Murphy, G
Knauper, V
Citation: Jo. Stracke et al., Biochemical characterization of the catalytic domain of human matrix metalloproteinase 19 - Evidence for a role as a potent basement membrane degrading enzyme, J BIOL CHEM, 275(20), 2000, pp. 14809-14816
Authors:
English, WR
Puente, XS
Freije, JMP
Knauper, V
Amour, A
Merryweather, A
Lopez-Otin, C
Murphy, G
Citation: Wr. English et al., Membrane type 4 matrix metalloproteinase (MMP17) has tumor necrosis factor-alpha convertase activity but does not activate pro-MMP2, J BIOL CHEM, 275(19), 2000, pp. 14046-14055
Authors:
Pendas, AM
Uria, JA
Jimenez, MG
Balbin, M
Freije, JP
Lopez-Otin, C
Citation: Am. Pendas et al., An overview of collagenase-3 expression in malignant tumors and analysis of its potential value as a target in antitumor therapies, CLIN CHIM A, 291(2), 2000, pp. 137-155
Authors:
Velasco, G
Cal, S
Merlos-Suarez, A
Ferrando, AA
Alvarez, S
Nakano, A
Arribas, J
Lopez-Otin, C
Citation: G. Velasco et al., Human MT6-matrix metalloproteinase: Identification, progelatinase A activation, and expression in brain tumors, CANCER RES, 60(4), 2000, pp. 877-882
Citation: Ja. Uria et C. Lopez-otin, Matrilysin-2, a new matrix metalloproteinase expressed in human tumors andshowing the minimal domain organization required for secretion, latency, and activity, CANCER RES, 60(17), 2000, pp. 4745-4751
Authors:
Scorilas, A
Diamandis, EP
Levesque, MA
Papanastasiou-Diamandi, A
Khosravi, MJ
Giai, M
Ponzone, R
Roagna, R
Sismondi, P
Lopez-Otin, C
Citation: A. Scorilas et al., Immunoenzymatically determined pepsinogen C concentration in breast tumor cytosols: An independent favorable prognostic factor in node-positive patients, CLIN CANC R, 5(7), 1999, pp. 1778-1785
Authors:
Konttinen, YT
Salo, T
Hanemaaijer, R
Valleala, H
Sorsa, T
Sutinen, M
Ceponis, A
Xu, JW
Santavirta, S
Teronen, O
Lopez-Otin, C
Citation: Yt. Konttinen et al., Collagenase-3 (MMP-13) and its activators in rheumatoid arthritis: localization in the pannus-hard tissue junction and inhibition by alendronate, MATRIX BIOL, 18(4), 1999, pp. 401-412
Authors:
Freije, JMP
Blay, P
Pendas, AM
Cadinanos, J
Crespo, P
Lopez-Otin, C
Citation: Jmp. Freije et al., Identification and chromosomal location of two human genes encoding enzymes potentially involved in proteolytic maturation of farnesylated proteins, GENOMICS, 58(3), 1999, pp. 270-280
Authors:
Jimenez, MJG
Balbin, M
Lopez, JM
Alvarez, J
Komori, T
Lopez-Otin, C
Citation: Mjg. Jimenez et al., Collagenase 3 is a target of Cbfa1, a transcription factor of the runt gene family involved in bone formation, MOL CELL B, 19(6), 1999, pp. 4431-4442
Authors:
Velasco, G
Pendas, AM
Fueyo, A
Knauper, V
Murphy, G
Lopez-Otin, C
Citation: G. Velasco et al., Cloning and characterization of human MMP-23, a new matrix metalloproteinase predominantly expressed in reproductive tissues and lacking conserved domains in other family members, J BIOL CHEM, 274(8), 1999, pp. 4570-4576
Authors:
Barmina, OY
Walling, HW
Fiacco, GJ
Freije, JMP
Lopez-Otin, C
Jeffrey, JJ
Partridge, NC
Citation: Oy. Barmina et al., Collagenase-3 binds to a specific receptor and requires the low density lipoprotein receptor-related protein for internalization, J BIOL CHEM, 274(42), 1999, pp. 30087-30093
Authors:
Ravanti, L
Heino, J
Lopez-Otin, C
Kahari, VM
Citation: L. Ravanti et al., Induction of collagenase-3 (MMP-13) expression in human skin fibroblasts by three-dimensional collagen is mediated by p38 mitogen-activated protein kinase, J BIOL CHEM, 274(4), 1999, pp. 2446-2455
Authors:
Santamaria, I
Velasco, G
Pendas, AM
Paz, A
Lopez-Otin, C
Citation: I. Santamaria et al., Molecular cloning and structural and functional characterization of human cathepsin F, a new cysteine proteinase of the papain family with a long propeptide domain, J BIOL CHEM, 274(20), 1999, pp. 13800-13809