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Results: 1-25 | 26-41
Results: 1-25/41
Regulated, adenovirus-mediated delivery of tyrosine hydroxylase suppressesgrowth of estrogen-induced pituitary prolactinomas
Authors: Williams, JC Stone, D Smith-Arica, JR Morris, ID Lowenstein, PR Castro, MG
Citation: Jc. Williams et al., Regulated, adenovirus-mediated delivery of tyrosine hydroxylase suppressesgrowth of estrogen-induced pituitary prolactinomas, MOL THER, 4(6), 2001, pp. 593-602
Towards global and long-term neurological gene therapy: Unexpected transgene dependent, high-level, and widespread distribution of HSV-1 thymidine kinase throughout the CNS
Authors: Zermansky, AJ Bolognani, F Stone, D Cowsill, CM Morrissey, G Castro, MG Lowenstein, PR
Citation: Aj. Zermansky et al., Towards global and long-term neurological gene therapy: Unexpected transgene dependent, high-level, and widespread distribution of HSV-1 thymidine kinase throughout the CNS, MOL THER, 4(5), 2001, pp. 490-498
Acute direct adenoviral vector cytotoxicity and chronic, but not acute, inflammatory responses correlate with decreased vector-mediated transgene expression in the brain
Authors: Thomas, CE Birkett, D Anozie, I Castro, MG Lowenstein, PR
Citation: Ce. Thomas et al., Acute direct adenoviral vector cytotoxicity and chronic, but not acute, inflammatory responses correlate with decreased vector-mediated transgene expression in the brain, MOL THER, 3(1), 2001, pp. 36-46
Efficient FLPe recombinase enables scalable production of helper-dependentadenoviral vectors with negligible helper-virus contamination
Authors: Umana, P Gerdes, CA Stone, D Davis, JRE Ward, D Castro, MG Lowenstein, PR
Citation: P. Umana et al., Efficient FLPe recombinase enables scalable production of helper-dependentadenoviral vectors with negligible helper-virus contamination, NAT BIOTECH, 19(6), 2001, pp. 582-585
Molecular therapy in a model neuroendocrine disease: developing clinical gene therapy for pituitary tumours
Authors: Castro, MG Southgate, T Lowenstein, PR
Citation: Mg. Castro et al., Molecular therapy in a model neuroendocrine disease: developing clinical gene therapy for pituitary tumours, TRENDS ENDO, 12(2), 2001, pp. 58-64
Preexisting antiadenoviral immunity is not a barrier to efficient and stable transduction of the brain, mediated by novel high-capacity adenovirus vectors
Authors: Thomas, CE Schiedner, G Kochanek, S Castro, MG Lowenstein, PR
Citation: Ce. Thomas et al., Preexisting antiadenoviral immunity is not a barrier to efficient and stable transduction of the brain, mediated by novel high-capacity adenovirus vectors, HUM GENE TH, 12(7), 2001, pp. 839-846
Death receptor-independent cytochrome c release and caspase activation mediate thymidine kinase plus ganciclovir-mediated cytotoxicity in LN-18 and LN-229 human malignant glioma cells
Authors: Glaser, T Castro, MG Lowenstein, PR Weller, M
Citation: T. Glaser et al., Death receptor-independent cytochrome c release and caspase activation mediate thymidine kinase plus ganciclovir-mediated cytotoxicity in LN-18 and LN-229 human malignant glioma cells, GENE THER, 8(6), 2001, pp. 469-476
Adenovirus-mediated expression of HSV1-TK or Fas ligand induces cell deathin primary human glioma-derived cell cultures that are resistant to the chemotherapeutic agent CCNU
Authors: Maleniak, TC Darling, JL Lowenstein, PR Castro, MG
Citation: Tc. Maleniak et al., Adenovirus-mediated expression of HSV1-TK or Fas ligand induces cell deathin primary human glioma-derived cell cultures that are resistant to the chemotherapeutic agent CCNU, CANC GENE T, 8(8), 2001, pp. 589-598
Gene therapy for Parkinson's disease: Recent achievements and remaining challenges
Authors: Castro, MG David, A Hurtado-Lorenzo, A Suwelack, D Millan, E Verakis, T Xiong, WD Yuan, XP Lowenstein, PR
Citation: Mg. Castro et al., Gene therapy for Parkinson's disease: Recent achievements and remaining challenges, HIST HISTOP, 16(4), 2001, pp. 1225-1238
Genetic engineering within the adult brain: Implications for molecular approaches to behavioral neuroscience
Authors: Lowenstein, PR Castro, MG
Citation: Pr. Lowenstein et Mg. Castro, Genetic engineering within the adult brain: Implications for molecular approaches to behavioral neuroscience, PHYSL BEHAV, 73(5), 2001, pp. 833-839
Efficient virus extinction by combinations of a mutagen and antiviral inhibitors
Authors: Pariente, N Sierra, S Lowenstein, PR Domingo, E
Citation: N. Pariente et al., Efficient virus extinction by combinations of a mutagen and antiviral inhibitors, J VIROLOGY, 75(20), 2001, pp. 9723-9730
Switching on and off transgene expression within lactotrophic cells in theanterior pituitary gland in vivo
Authors: Smith-Arica, JR Williams, JC Stone, D Smith, J Lowenstein, PR Castro, MG
Citation: Jr. Smith-arica et al., Switching on and off transgene expression within lactotrophic cells in theanterior pituitary gland in vivo, ENDOCRINOL, 142(6), 2001, pp. 2521-2532
Cell type-specific adenoviral transgene expression in the intact ovine pituitary gland after stereotaxic delivery: An in vivo system for long-term multiple parameter evaluation of human pituitary gene therapy
Authors: Davis, JRE McVerry, J Lincoln, GA Windeatt, S Lowenstein, PR Castro, MG McNeilly, AS
Citation: Jre. Davis et al., Cell type-specific adenoviral transgene expression in the intact ovine pituitary gland after stereotaxic delivery: An in vivo system for long-term multiple parameter evaluation of human pituitary gene therapy, ENDOCRINOL, 142(2), 2001, pp. 795-801
Long-term transgene expression within the anterior pituitary gland in situ: Impact on circulating hormone levels, cellular and antibody-mediated immune responses
Authors: Southgate, TD Stone, D Williams, JC Lowenstein, PR Castro, MG
Citation: Td. Southgate et al., Long-term transgene expression within the anterior pituitary gland in situ: Impact on circulating hormone levels, cellular and antibody-mediated immune responses, ENDOCRINOL, 142(1), 2001, pp. 464-476
Adenovirus-mediated gene transfer of a secreted transforming growth factor-beta type II receptor inhibits luminal loss and constrictive remodeling after coronary angioplasty and enhances adventitial collagen deposition
Authors: Kingston, PA Sinha, S David, A Castro, MG Lowenstein, PR Heagerty, AM
Citation: Pa. Kingston et al., Adenovirus-mediated gene transfer of a secreted transforming growth factor-beta type II receptor inhibits luminal loss and constrictive remodeling after coronary angioplasty and enhances adventitial collagen deposition, CIRCULATION, 104(21), 2001, pp. 2595-2601
Transient transgenesis in the endocrine system: Viral vectors for gene delivery
Authors: David, A Stone, D Cowen, RL Castro, MG Lowenstein, PR
Citation: A. David et al., Transient transgenesis in the endocrine system: Viral vectors for gene delivery, ENDOC UPD S, 13, 2001, pp. 195-232
Cell-type-specific and regulatable transgenesis in the adult brain: Adenovirus-encoded combined transcriptional targeting and inducible transgene expression
Authors: Smith-Arica, JR Morelli, AE Larregina, AT Smith, J Lowenstein, PR Castro, MG
Citation: Jr. Smith-arica et al., Cell-type-specific and regulatable transgenesis in the adult brain: Adenovirus-encoded combined transcriptional targeting and inducible transgene expression, MOL THER, 2(6), 2000, pp. 579-587
Strong promoters are the key to highly efficient, noninflammatory and noncytotoxic adenoviral-mediated transgene delivery into the brain in vivo (vol2, pg 330, 2000)
Authors: Gerdes, CA Castro, MG Lowenstein, PR
Citation: Ca. Gerdes et al., Strong promoters are the key to highly efficient, noninflammatory and noncytotoxic adenoviral-mediated transgene delivery into the brain in vivo (vol2, pg 330, 2000), MOL THER, 2(6), 2000, pp. 660-660
Strong promoters are the key to highly efficient, noninflammatory and noncytotoxic adenoviral-mediated transgene delivery into the brain in vivo
Authors: Gerdes, CA Castro, MG Lowenstein, PR
Citation: Ca. Gerdes et al., Strong promoters are the key to highly efficient, noninflammatory and noncytotoxic adenoviral-mediated transgene delivery into the brain in vivo, MOL THER, 2(4), 2000, pp. 330-338
Central nervous system toxicity of two adenoviral vectors encoding variants of the herpes simplex virus type 1 thymidine kinase: reduced cytotoxicityof a truncated HSV1-TK
Authors: Cowsill, C Southgate, TD Morrissey, G Dewey, RA Morelli, AE Maleniak, TC Forrest, Z Klatzmann, D Wilkinson, GWG Lowenstein, PR Castro, MG
Citation: C. Cowsill et al., Central nervous system toxicity of two adenoviral vectors encoding variants of the herpes simplex virus type 1 thymidine kinase: reduced cytotoxicityof a truncated HSV1-TK, GENE THER, 7(8), 2000, pp. 679-685
Subcellular post-transcriptional targeting: delivery of an intracellular protein to the extracellular leaflet of the plasma membrane using a glycosyl-phosphatidyl inositol (GPI) membrane anchor in neurons and polarised epithelial cells
Authors: Brown, O Cowen, RL Preston, CM Castro, MG Lowenstein, PR
Citation: O. Brown et al., Subcellular post-transcriptional targeting: delivery of an intracellular protein to the extracellular leaflet of the plasma membrane using a glycosyl-phosphatidyl inositol (GPI) membrane anchor in neurons and polarised epithelial cells, GENE THER, 7(22), 2000, pp. 1947-1953
Gene therapy strategies for intracranial tumours: glioma and pituitary adenomas
Authors: Castro, MG Cowen, R Smith-Arica, J Williams, J Ali, S Windeatt, S Gonzalez-Nicolini, V Maleniak, T Lowenstein, PR
Citation: Mg. Castro et al., Gene therapy strategies for intracranial tumours: glioma and pituitary adenomas, HIST HISTOP, 15(4), 2000, pp. 1233-1252
Un pour tous, tous pour un
Authors: Lowenstein, PR
Citation: Pr. Lowenstein, Un pour tous, tous pour un, TRENDS NEUR, 23(10), 2000, pp. 467-468
Fas ligand-transfected myoblasts and islet cell transplantation
Authors: Turvey, SE Gonzalez-Nicolini, V Kingsley, CI Larregina, AT Morris, PJ Castro, MG Lowenstein, PR Wood, KJ
Citation: Se. Turvey et al., Fas ligand-transfected myoblasts and islet cell transplantation, TRANSPLANT, 69(9), 2000, pp. 1972-1976
Peripheral infection with adenovirus causes unexpected long-term brain inflammation in animals injected intracranially with first-generation, but notwith high-capacity, adenovirus vectors: Toward realistic long-term neurological gene therapy for chronic diseases
Authors: Thomas, CE Schiedner, G Kochanek, S Castro, MG Lowenstein, PR
Citation: Ce. Thomas et al., Peripheral infection with adenovirus causes unexpected long-term brain inflammation in animals injected intracranially with first-generation, but notwith high-capacity, adenovirus vectors: Toward realistic long-term neurological gene therapy for chronic diseases, P NAS US, 97(13), 2000, pp. 7482-7487
Risultati: 1-25 | 26-41