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Results: 1-7 |
Results: 7
Bone-targeted Src SH2 inhibitors block Src cellular activity and osteoclast-mediated resorption
Authors: Violette, SM Guan, W Bartlett, C Smith, JA Bardelay, C Antoine, E Rickles, RJ Mandine, E Van Schravendijk, MR Adams, SE Lynch, BA Shakespeare, WC Yang, M Jacobsen, VA Takeuchi, CS Macek, KJ Bohacek, RS Dalgarno, DC Weigele, M Lesuisse, D Sawyer, TK Baron, R
Citation: Sm. Violette et al., Bone-targeted Src SH2 inhibitors block Src cellular activity and osteoclast-mediated resorption, BONE, 28(1), 2001, pp. 54-64
X-ray structure of citrate bound to Src SH2 leads to a high-affinity, bone-targeted Src SH2 inhibitor
Authors: Bohacek, RS Dalgarno, DC Hatada, M Jacobsen, VA Lynch, BA Macek, KJ Merry, T Metcalf, CA Narula, SS Sawyer, TK Shakespeare, WC Violette, SM Weigele, M
Citation: Rs. Bohacek et al., X-ray structure of citrate bound to Src SH2 leads to a high-affinity, bone-targeted Src SH2 inhibitor, J MED CHEM, 44(5), 2001, pp. 660-663
Structure-based design and solid-phase parallel synthesis of phosphorylated nonpeptides to explore hydrophobic binding at the Src SH2 domain
Authors: Metcalf, CA Eyermann, CJ Bohacek, RS Haraldson, CA Varkhedkar, VM Lynch, BA Bartlett, C Violette, SM Sawyer, TK
Citation: Ca. Metcalf et al., Structure-based design and solid-phase parallel synthesis of phosphorylated nonpeptides to explore hydrophobic binding at the Src SH2 domain, J COMB CHEM, 2(4), 2000, pp. 305-313
Cloning the soil metagenome: a strategy for accessing the genetic and functional diversity of uncultured microorganisms
Authors: Rondon, MR August, PR Bettermann, AD Brady, SF Grossman, TH Liles, MR Loiacono, KA Lynch, BA MacNeil, IA Minor, C Tiong, CL Gilman, M Osburne, MS Clardy, J Handelsman, J Goodman, RM
Citation: Mr. Rondon et al., Cloning the soil metagenome: a strategy for accessing the genetic and functional diversity of uncultured microorganisms, APPL ENVIR, 66(6), 2000, pp. 2541-2547
Structure-activity relationships of a novel class of Src SH2 inhibitors
Authors: Buchanan, JL Vu, CB Merry, TJ Corpuz, EG Pradeepan, SG Mani, UN Yang, M Plake, HR Varkhedkar, VM Lynch, BA MacNeil, IA Loiacono, KA Tiong, CL Holt, DA
Citation: Jl. Buchanan et al., Structure-activity relationships of a novel class of Src SH2 inhibitors, BIOORG MED, 9(16), 1999, pp. 2359-2364
Discovery of potent and selective SH2 inhibitors of the tyrosine kinase ZAP-70
Authors: Vu, CB Corpuz, EG Merry, TJ Pradeepan, SG Bartlett, C Bohacek, RS Botfield, MC Eyermann, CJ Lynch, BA MacNeil, IA Ram, MK van Schravendijk, MR Violette, S Sawyer, TK
Citation: Cb. Vu et al., Discovery of potent and selective SH2 inhibitors of the tyrosine kinase ZAP-70, J MED CHEM, 42(20), 1999, pp. 4088-4098
Simultaneous assay of Src SH3 and SH2 domain binding using different wavelength fluorescence polarization probes
Authors: Lynch, BA Minor, C Loiacono, KA van Schravendijk, MR Ram, MK Sundaramoorthi, R Adams, SE Phillips, T Holt, D Rickles, RJ MacNeil, IA
Citation: Ba. Lynch et al., Simultaneous assay of Src SH3 and SH2 domain binding using different wavelength fluorescence polarization probes, ANALYT BIOC, 275(1), 1999, pp. 62-73
Risultati: 1-7 |