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Results: 1-10 |
Results: 10
PROTEIN STRUCTURE-BASED DESIGN, SYNTHESIS, AND BIOLOGICAL EVALUATION OF 5-THIA-2,6-DIAMINO-4(3H)-OXOPYRIMIDINES - POTENT INHIBITORS OF GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE WITH POTENT CELL-GROWTH INHIBITION
Authors: VARNEY MD PALMER CL ROMINES WH BORITZKI T MARGOSIAK SA ALMASSY R JANSON CA BARTLETT C HOWLAND EJ FERRE R
Citation: Md. Varney et al., PROTEIN STRUCTURE-BASED DESIGN, SYNTHESIS, AND BIOLOGICAL EVALUATION OF 5-THIA-2,6-DIAMINO-4(3H)-OXOPYRIMIDINES - POTENT INHIBITORS OF GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE WITH POTENT CELL-GROWTH INHIBITION, Journal of medicinal chemistry, 40(16), 1997, pp. 2502-2524
MMP INHIBITION-KINETICS AND PROTEIN-STRUCTURE - IMPLICATION FOR THE SLOW-BINDING OF INHIBITORS TO MATRILYSIN AND STROMELYSIN
Authors: HOWLAND EF APPELT K BROWNER M MARGOSIAK SA
Citation: Ef. Howland et al., MMP INHIBITION-KINETICS AND PROTEIN-STRUCTURE - IMPLICATION FOR THE SLOW-BINDING OF INHIBITORS TO MATRILYSIN AND STROMELYSIN, The FASEB journal, 10(6), 1996, pp. 756-756
AG337, A NOVEL LIPOPHILIC THYMIDYLATE SYNTHASE INHIBITOR - IN-VITRO AND IN-VIVO PRECLINICAL STUDIES
Authors: WEBBER S BARTLETT CA BORITZKI TJ HILLIARD JA HOWLAND EF JOHNSTON AL KOSA M MARGOSIAK SA MORSE CA SHETTY BV
Citation: S. Webber et al., AG337, A NOVEL LIPOPHILIC THYMIDYLATE SYNTHASE INHIBITOR - IN-VITRO AND IN-VIVO PRECLINICAL STUDIES, Cancer chemotherapy and pharmacology, 37(6), 1996, pp. 509-517
AG2034 - A NOVEL INHIBITOR OF GLYCINAMIDE RIBONUCLEOTIDE FORMYLTRANSFERASE
Authors: BORITZKI TJ BARLETT CA ZHANG C HOWLAND EE MARGOSIAK SA PALMER CL ROMINES WH JACKSON RC
Citation: Tj. Boritzki et al., AG2034 - A NOVEL INHIBITOR OF GLYCINAMIDE RIBONUCLEOTIDE FORMYLTRANSFERASE, Investigational new drugs, 14(3), 1996, pp. 295-303
STRUCTURE OF THE HUMAN CYTOMEGALOVIRUS PROTEASE CATALYTIC DOMAIN REVEALS A NOVEL SERINE-PROTEASE FOLD AND CATALYTIC TRIAD
Authors: CHEN P TSUGE H ALMASSY RJ GRIBSKOV CL KATOH S VANDERPOOL DL MARGOSIAK SA PINKO C MATTHEWS DA KAN CC
Citation: P. Chen et al., STRUCTURE OF THE HUMAN CYTOMEGALOVIRUS PROTEASE CATALYTIC DOMAIN REVEALS A NOVEL SERINE-PROTEASE FOLD AND CATALYTIC TRIAD, Cell, 86(5), 1996, pp. 835-843
DIMERIZATION OF THE HUMAN CYTOMEGALOVIRUS PROTEASE - KINETIC AND BIOCHEMICAL-CHARACTERIZATION OF THE CATALYTIC HOMODIMER
Authors: MARGOSIAK SA VANDERPOOL DL SISSON W PINKO C KAN CC
Citation: Sa. Margosiak et al., DIMERIZATION OF THE HUMAN CYTOMEGALOVIRUS PROTEASE - KINETIC AND BIOCHEMICAL-CHARACTERIZATION OF THE CATALYTIC HOMODIMER, Biochemistry, 35(16), 1996, pp. 5300-5307
SYNTHESIS AND BIOLOGICAL EVALUATION OF IN-5-YL]METHYL)THIO]CYCLOBUTYL)BENZOYL]-L-GLUTAMIC ACID A NOVEL 5-THIAPYRIMIDINONE INHIBITOR OF DIHYDROFOLATE-REDUCTASE
Authors: VARNEY MD ROMINES WH BORITZKI T MARGOSIAK SA BARTLETT C HOWLAND EJ
Citation: Md. Varney et al., SYNTHESIS AND BIOLOGICAL EVALUATION OF IN-5-YL]METHYL)THIO]CYCLOBUTYL)BENZOYL]-L-GLUTAMIC ACID A NOVEL 5-THIAPYRIMIDINONE INHIBITOR OF DIHYDROFOLATE-REDUCTASE, Journal of heterocyclic chemistry, 32(5), 1995, pp. 1493-1498
SINGLE-CHAIN RECOMBINANT HUMAN CYTOMEGALOVIRUS PROTEASE - ACTIVITY AGAINST ITS NATURAL PROTEIN SUBSTRATE AND FLUOROGENIC PEPTIDE SUBSTRATES
Authors: PINKO C MARGOSIAK SA VANDERPOOL D GUTOWSKI JC CONDON B KAN CC
Citation: C. Pinko et al., SINGLE-CHAIN RECOMBINANT HUMAN CYTOMEGALOVIRUS PROTEASE - ACTIVITY AGAINST ITS NATURAL PROTEIN SUBSTRATE AND FLUOROGENIC PEPTIDE SUBSTRATES, The Journal of biological chemistry, 270(40), 1995, pp. 23634-23640
CHARACTERIZATION OF THE PHE-81 AND VAL-82 HUMAN FIBROBLAST COLLAGENASE CATALYTIC DOMAIN PURIFIED FROM ESCHERICHIA-COLI
Authors: GEHRING MR CONDON B MARGOSIAK SA KAN CC
Citation: Mr. Gehring et al., CHARACTERIZATION OF THE PHE-81 AND VAL-82 HUMAN FIBROBLAST COLLAGENASE CATALYTIC DOMAIN PURIFIED FROM ESCHERICHIA-COLI, The Journal of biological chemistry, 270(38), 1995, pp. 22507-22513
DIHYDROFOLATE-REDUCTASE FROM THE PATHOGENIC FUNGUS PNEUMOCYSTIS-CARINII - CATALYTIC PROPERTIES AND INTERACTION WITH ANTIFOLATES
Authors: MARGOSIAK SA APPLEMAN JR SANTI DV BLAKLEY RL
Citation: Sa. Margosiak et al., DIHYDROFOLATE-REDUCTASE FROM THE PATHOGENIC FUNGUS PNEUMOCYSTIS-CARINII - CATALYTIC PROPERTIES AND INTERACTION WITH ANTIFOLATES, Archives of biochemistry and biophysics, 305(2), 1993, pp. 499-508
Risultati: 1-10 |