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Results: 1-20 |
Results: 20
INHIBITORS OF GLUTATHIONE-REDUCTASE AS POTENTIAL ANTIMALARIAL-DRUGS -KINETIC COOPERATIVITY AND EFFECT OF DIMETHYL-SULFOXIDE ON INHIBITION-KINETICS
Authors: LUOND RM MCKIE JH DOUGLAS KT DASCOMBE MJ VALE J
Citation: Rm. Luond et al., INHIBITORS OF GLUTATHIONE-REDUCTASE AS POTENTIAL ANTIMALARIAL-DRUGS -KINETIC COOPERATIVITY AND EFFECT OF DIMETHYL-SULFOXIDE ON INHIBITION-KINETICS, Journal of enzyme inhibition, 13(5), 1998, pp. 327-345
RATIONAL DRUG DESIGN APPROACH FOR OVERCOMING DRUG-RESISTANCE - APPLICATION TO PYRIMETHAMINE RESISTANCE IN MALARIA
Authors: MCKIE JH DOUGLAS KT CHAN C ROSER SA YATES R READ M HYDE JE DASCOMBE MJ YUTHAVONG Y SIRAWARAPORN W
Citation: Jh. Mckie et al., RATIONAL DRUG DESIGN APPROACH FOR OVERCOMING DRUG-RESISTANCE - APPLICATION TO PYRIMETHAMINE RESISTANCE IN MALARIA, Journal of medicinal chemistry, 41(9), 1998, pp. 1367-1370
PHENOTHIAZINE INHIBITORS OF TRYPANOTHIONE REDUCTASE AS POTENTIAL ANTITRYPANOSOMAL AND ANTILEISHMANIAL DRUGS (VOL 41, PG 150, 1998)
Authors: CHAN C YIN H GARFORTH J MCKIE JH JAOUHARI R SPEERS P DOUGLAS KT ROCK PJ YARDLEY V CROFT SL FAIRLAMB AH
Citation: C. Chan et al., PHENOTHIAZINE INHIBITORS OF TRYPANOTHIONE REDUCTASE AS POTENTIAL ANTITRYPANOSOMAL AND ANTILEISHMANIAL DRUGS (VOL 41, PG 150, 1998), Journal of medicinal chemistry, 41(24), 1998, pp. 4910-4910
PHENOTHIAZINE INHIBITORS OF TRYPANOTHIONE REDUCTASE AS POTENTIAL ANTITRYPANOSOMAL AND ANTILEISHMANIAL DRUGS
Authors: CHAN C YIN H GARFORTH J MCKIE JH JAOUHARI R SPEERS P DOUGLAS KT ROCK PJ YARDLEY V CROFT SL FAIRLAMB AH
Citation: C. Chan et al., PHENOTHIAZINE INHIBITORS OF TRYPANOTHIONE REDUCTASE AS POTENTIAL ANTITRYPANOSOMAL AND ANTILEISHMANIAL DRUGS, Journal of medicinal chemistry, 41(2), 1998, pp. 148-156
RATIONAL DESIGN OF SELECTIVE LIGANDS FOR TRYPANOTHIONE REDUCTASE FROMTRYPANOSOMA-CRUZI - STRUCTURAL EFFECTS ON THE INHIBITION BY DIBENZAZEPINES BASED ON IMIPRAMINE
Authors: GARFORTH J YIN H MCKIE JH DOUGLAS KT FAIRLAMB AH
Citation: J. Garforth et al., RATIONAL DESIGN OF SELECTIVE LIGANDS FOR TRYPANOTHIONE REDUCTASE FROMTRYPANOSOMA-CRUZI - STRUCTURAL EFFECTS ON THE INHIBITION BY DIBENZAZEPINES BASED ON IMIPRAMINE, Journal of enzyme inhibition, 12(3), 1997, pp. 161-173
SYNTHESIS OF SYMMETRICAL DISULFIDES AS POTENTIAL ALTERNATIVE SUBSTRATES FOR TRYPANOTHIONE REDUCTASE AND GLUTATHIONE-REDUCTASE .1.
Authors: JAOUHARI R BESHEYA T MCKIE JH DOUGLAS KT
Citation: R. Jaouhari et al., SYNTHESIS OF SYMMETRICAL DISULFIDES AS POTENTIAL ALTERNATIVE SUBSTRATES FOR TRYPANOTHIONE REDUCTASE AND GLUTATHIONE-REDUCTASE .1., Amino acids, 9(4), 1995, pp. 327-342
SYNTHESIS OF ASYMMETRIC DISULFIDES AS POTENTIAL ALTERNATIVE SUBSTRATES FOR TRYPANOTHIONE REDUCTASE AND GLUTATHIONE-REDUCTASE .2.
Authors: JAOUHARI R BESHEYA T MCKIE JH DOUGLAS KT
Citation: R. Jaouhari et al., SYNTHESIS OF ASYMMETRIC DISULFIDES AS POTENTIAL ALTERNATIVE SUBSTRATES FOR TRYPANOTHIONE REDUCTASE AND GLUTATHIONE-REDUCTASE .2., Amino acids, 9(4), 1995, pp. 343-351
INHIBITORS OF TRYPANOTHIONE REDUCTASE AS POTENTIAL ANTITRYPANOSOMAL DRUGS
Authors: CHAN C YIN H GARFORTH J MCKIE JH JAOUHARI RA DOUGLAS KT FAIRLAMB AH CROFT SL
Citation: C. Chan et al., INHIBITORS OF TRYPANOTHIONE REDUCTASE AS POTENTIAL ANTITRYPANOSOMAL DRUGS, Biochemical Society transactions, 23(4), 1995, pp. 511-511
A HOMOLOGY MODEL OF THE 3-DIMENSIONAL STRUCTURE OF HUMAN O-6-ALKYLGUANINE-DNA ALKYLTRANSFERASE BASED ON THE CRYSTAL-STRUCTURE OF THE C-TERMINAL DOMAIN OF THE ADA PROTEIN FROM ESCHERICHIA-COLI (VOL 10, PG 75, 1995)
Authors: WIBLEY JEA MCKIE JH EMBREY K MARKS DS DOUGLAS KT MOORE MH MOODY PCE
Citation: Jea. Wibley et al., A HOMOLOGY MODEL OF THE 3-DIMENSIONAL STRUCTURE OF HUMAN O-6-ALKYLGUANINE-DNA ALKYLTRANSFERASE BASED ON THE CRYSTAL-STRUCTURE OF THE C-TERMINAL DOMAIN OF THE ADA PROTEIN FROM ESCHERICHIA-COLI (VOL 10, PG 75, 1995), Anti-cancer drug design, 10(5), 1995, pp. 439-439
A HOMOLOGY MODEL OF THE 3-DIMENSIONAL STRUCTURE OF HUMAN O-6-ALKYLGUANINE-DNA ALKYLTRANSFERASE BASED ON THE CRYSTAL-STRUCTURE OF THE C-TERMINAL DOMAIN OF THE ADA PROTEIN FROM ESCHERICHIA-COLI
Authors: WIBLEY JEA MCKIE JH EMBREY K MARKS DS DOUGLAS KT MOORE MH MOODY PCE
Citation: Jea. Wibley et al., A HOMOLOGY MODEL OF THE 3-DIMENSIONAL STRUCTURE OF HUMAN O-6-ALKYLGUANINE-DNA ALKYLTRANSFERASE BASED ON THE CRYSTAL-STRUCTURE OF THE C-TERMINAL DOMAIN OF THE ADA PROTEIN FROM ESCHERICHIA-COLI, Anti-cancer drug design, 10(1), 1995, pp. 75-95
PREDICTABILITY OF DESIGNING SPECIFIC BINDING INTERACTIONS FOR DNA MINOR-GROOVE LIGANDS FROM NMR-SPECTROSCOPY AND MOLECULAR MODELING - A COPPER(II)-ACTIVATED DNA CLEAVER BASED ON HOECHST-33258
Authors: PARKINSON J SADATEBRAHIMI S WILTON A MCKIE JH ANDREWS J DOUGLAS KT
Citation: J. Parkinson et al., PREDICTABILITY OF DESIGNING SPECIFIC BINDING INTERACTIONS FOR DNA MINOR-GROOVE LIGANDS FROM NMR-SPECTROSCOPY AND MOLECULAR MODELING - A COPPER(II)-ACTIVATED DNA CLEAVER BASED ON HOECHST-33258, Biochemistry, 34(50), 1995, pp. 16240-16244
SITE-DIRECTED MUTAGENESIS OF A SERINE RESIDUE IN CINNAMYL ALCOHOL-DEHYDROGENASE, A PLANT NADPH-DEPENDENT DEHYDROGENASE, AFFECTS THE SPECIFICITY FOR THE COENZYME
Authors: LAUVERGEAT V KENNEDY K FEUILLET C MCKIE JH GORRICHON L BALTAS M BOUDET AM GRIMAPETTENATI J DOUGLAS KT
Citation: V. Lauvergeat et al., SITE-DIRECTED MUTAGENESIS OF A SERINE RESIDUE IN CINNAMYL ALCOHOL-DEHYDROGENASE, A PLANT NADPH-DEPENDENT DEHYDROGENASE, AFFECTS THE SPECIFICITY FOR THE COENZYME, Biochemistry, 34(38), 1995, pp. 12426-12434
RATIONAL DESIGN OF PEPTIDE-BASED INHIBITORS OF TRYPANOTHIONE REDUCTASE AS POTENTIAL ANTITRYPANOSOMAL DRUGS
Authors: GARFORTH J MCKIE JH JAOUHARI R BENSON TJ FAIRLAMB AH DOUGLAS KT
Citation: J. Garforth et al., RATIONAL DESIGN OF PEPTIDE-BASED INHIBITORS OF TRYPANOTHIONE REDUCTASE AS POTENTIAL ANTITRYPANOSOMAL DRUGS, Amino acids, 6(3), 1994, pp. 295-299
PHOTOAFFINITY-LABELING OF THE ACTIVE-SITE OF THE RAT GLUTATHIONE TRANSFERASE-3-3 AND TRANSFERASE-1-1 AND HUMAN GLUTATHIONE TRANSFERASE A1-1
Authors: COOKE RJ BJORNESTEDT R DOUGLAS KT MCKIE JH KING MD COLES B KETTERER B MANNERVIK B
Citation: Rj. Cooke et al., PHOTOAFFINITY-LABELING OF THE ACTIVE-SITE OF THE RAT GLUTATHIONE TRANSFERASE-3-3 AND TRANSFERASE-1-1 AND HUMAN GLUTATHIONE TRANSFERASE A1-1, Biochemical journal, 302, 1994, pp. 383-390
USE OF TRANSFERRED NUCLEAR-OVERHAUSER-EFFECT SPECTROSCOPY TO MEASURE THE BOUND CONFORMATION OF A DISULFIDE-REPLACED ANALOG OF GLUTATHIONE DISULFIDE AS AN INHIBITOR OF YEAST GLUTATHIONE-REDUCTASE
Authors: EMBREY KJ MEHTA A CARRINGTON SJ JAOUHARI R MCKIE JH DOUGLAS KT
Citation: Kj. Embrey et al., USE OF TRANSFERRED NUCLEAR-OVERHAUSER-EFFECT SPECTROSCOPY TO MEASURE THE BOUND CONFORMATION OF A DISULFIDE-REPLACED ANALOG OF GLUTATHIONE DISULFIDE AS AN INHIBITOR OF YEAST GLUTATHIONE-REDUCTASE, European journal of biochemistry, 221(2), 1994, pp. 793-799
MOLECULAR DESIGN OF DNA-DIRECTED LIGANDS WITH SPECIFIC INTERACTIONS -SOLUTION NMR-STUDIES OF THE INTERACTION OF A M-HYDROXY ANALOG OF HOECHST-33258 WITH D(CGCGAATTCGCG)(2)
Authors: PARKINSON JA EBRAHIMI SE MCKIE JH DOUGLAS KT
Citation: Ja. Parkinson et al., MOLECULAR DESIGN OF DNA-DIRECTED LIGANDS WITH SPECIFIC INTERACTIONS -SOLUTION NMR-STUDIES OF THE INTERACTION OF A M-HYDROXY ANALOG OF HOECHST-33258 WITH D(CGCGAATTCGCG)(2), Biochemistry, 33(28), 1994, pp. 8442-8452
STRUCTURAL RELATIONSHIPS BETWEEN GLYOXALASE-I AND MEMBRANE-TRANSPORT PROTEINS
Authors: MCKIE JH DOUGLAS KT
Citation: Jh. Mckie et Kt. Douglas, STRUCTURAL RELATIONSHIPS BETWEEN GLYOXALASE-I AND MEMBRANE-TRANSPORT PROTEINS, Biochemical Society transactions, 21(2), 1993, pp. 540-544
THE GLUTAMYL BINDING-SITE OF TRYPANOTHIONE REDUCTASE FROM CRITHIDIA-FASCICULATA - ENZYME-KINETIC PROPERTIES OF GAMMA-GLUTAMYL-MODIFIED SUBSTRATE-ANALOGS
Authors: ELWAER AF SMITH K MCKIE JH BENSON T FAIRLAMB AH DOUGLAS KT
Citation: Af. Elwaer et al., THE GLUTAMYL BINDING-SITE OF TRYPANOTHIONE REDUCTASE FROM CRITHIDIA-FASCICULATA - ENZYME-KINETIC PROPERTIES OF GAMMA-GLUTAMYL-MODIFIED SUBSTRATE-ANALOGS, Biochimica et biophysica acta, 1203(1), 1993, pp. 93-98
A MOLECULAR-MODEL FOR CINNAMYL ALCOHOL-DEHYDROGENASE, A PLANT AROMATIC ALCOHOL-DEHYDROGENASE INVOLVED IN LIGNIFICATION
Authors: MCKIE JH JAOUHARI R DOUGLAS KT GOFFNER D FEUILLET C GRIMAPETTENATI J BOUDET AM BALTAS M GORRICHON L
Citation: Jh. Mckie et al., A MOLECULAR-MODEL FOR CINNAMYL ALCOHOL-DEHYDROGENASE, A PLANT AROMATIC ALCOHOL-DEHYDROGENASE INVOLVED IN LIGNIFICATION, Biochimica et biophysica acta, 1202(1), 1993, pp. 61-69
A DIRECT LINK BETWEEN LY83583, A SELECTIVE REPRESSOR OF CYCLIC-GMP FORMATION, AND GLUTATHIONE METABOLISM
Authors: LUOND RM MCKIE JH DOUGLAS KT
Citation: Rm. Luond et al., A DIRECT LINK BETWEEN LY83583, A SELECTIVE REPRESSOR OF CYCLIC-GMP FORMATION, AND GLUTATHIONE METABOLISM, Biochemical pharmacology, 45(12), 1993, pp. 2547-2549
Risultati: 1-20 |