AAAAAA

   
Results: 1-19 |
Results: 19
NOVEL BIOLOGICALLY-ACTIVE NONPEPTIDIC INHIBITORS OF MYRISTOYLCOA-PROTEIN N-MYRISTOYLTRANSFERASE
Authors: DEVADAS B FREEMAN SK MCWHERTER CA KISHORE NS LODGE JK JACKSONMACHELSKI E GORDON JI SIKORSKI JA
Citation: B. Devadas et al., NOVEL BIOLOGICALLY-ACTIVE NONPEPTIDIC INHIBITORS OF MYRISTOYLCOA-PROTEIN N-MYRISTOYLTRANSFERASE, Journal of medicinal chemistry, 41(6), 1998, pp. 996-1000
GENETIC AND BIOCHEMICAL-STUDIES ESTABLISH THAT THE FUNGICIDAL EFFECT OF A FULLY DEPEPTIDIZED INHIBITOR OF CRYPTOCOCCUS-NEOFORMANS MYRISTOYL-COA-PROTEIN N-MYRISTOYLTRANSFERASE (NMT) IS NMT-DEPENDENT
Authors: LODGE JK JACKSONMACHELSKI E HIGGINS M MCWHERTER CA SIKORSKI JA DEVADAS B GORDON JI
Citation: Jk. Lodge et al., GENETIC AND BIOCHEMICAL-STUDIES ESTABLISH THAT THE FUNGICIDAL EFFECT OF A FULLY DEPEPTIDIZED INHIBITOR OF CRYPTOCOCCUS-NEOFORMANS MYRISTOYL-COA-PROTEIN N-MYRISTOYLTRANSFERASE (NMT) IS NMT-DEPENDENT, The Journal of biological chemistry, 273(20), 1998, pp. 12482-12491
N-MYRISTOYLATION OF ARF PROTEINS IN CANDIDA-ALBICANS - AN IN-VIVO ASSAY FOR EVALUATING ANTIFUNGAL INHIBITORS OF MYRISTOYL-COA - PROTEIN N-MYRISTOYLTRANSFERASE
Authors: LODGE JK JACKSONMACHELSKI E DEVADAS B ZUPEC ME GETMAN DP KISHORE N FREEMAN SK MCWHERTER CA SIKORSKI JA GORDON JI
Citation: Jk. Lodge et al., N-MYRISTOYLATION OF ARF PROTEINS IN CANDIDA-ALBICANS - AN IN-VIVO ASSAY FOR EVALUATING ANTIFUNGAL INHIBITORS OF MYRISTOYL-COA - PROTEIN N-MYRISTOYLTRANSFERASE, Microbiology, 143, 1997, pp. 357-366
MULTIPLE CONFORMATIONS OF A HUMAN INTERLEUKIN-3 VARIANT
Authors: FENG YQ HOOD WF FORGEY RW ABEGG AL CAPARON MH THIELE BR LEIMGRUBER RM MCWHERTER CA
Citation: Yq. Feng et al., MULTIPLE CONFORMATIONS OF A HUMAN INTERLEUKIN-3 VARIANT, Protein science, 6(8), 1997, pp. 1777-1782
REPLACEMENTS FOR LYSINE IN L-SERYL-L-LYSYL DIPEPTIDE AMIDE INHIBITORSOF CANDIDA-ALBICANS MYRISTOYL-COA - PROTEIN N-MYRISTOYLTRANSFERASE
Authors: BROWN DL DEVADAS B LU HF NAGARAJAN S ZUPEC ME FREEMAN SK MCWHERTER CA GETMAN DP SIKORSKI JA
Citation: Dl. Brown et al., REPLACEMENTS FOR LYSINE IN L-SERYL-L-LYSYL DIPEPTIDE AMIDE INHIBITORSOF CANDIDA-ALBICANS MYRISTOYL-COA - PROTEIN N-MYRISTOYLTRANSFERASE, Bioorganic & medicinal chemistry letters, 7(3), 1997, pp. 379-382
DESIGN AND SYNTHESIS OF NOVEL IMIDAZOLE-SUBSTITUTED DIPEPTIDE AMIDES AS POTENT AND SELECTIVE INHIBITORS OF CANDIDA-ALBICANS MYRISTOYLCOA-PROTEIN N-MYRISTOYLTRANSFERASE AND IDENTIFICATION OF RELATED TRIPEPTIDE INHIBITORS WITH MECHANISM-BASED ANTIFUNGAL ACTIVITY
Authors: DEVADAS B FREEMAN SK ZUPEC ME LU HF NAGARAJAN SR KISHORE NS LODGE JK KUNEMAN DW MCWHERTER CA VINJAMOORI DV GETMAN DP GORDON JI SIKORSKI JA
Citation: B. Devadas et al., DESIGN AND SYNTHESIS OF NOVEL IMIDAZOLE-SUBSTITUTED DIPEPTIDE AMIDES AS POTENT AND SELECTIVE INHIBITORS OF CANDIDA-ALBICANS MYRISTOYLCOA-PROTEIN N-MYRISTOYLTRANSFERASE AND IDENTIFICATION OF RELATED TRIPEPTIDE INHIBITORS WITH MECHANISM-BASED ANTIFUNGAL ACTIVITY, Journal of medicinal chemistry, 40(16), 1997, pp. 2609-2625
CONFORMATIONALLY CONSTRAINED [P-(OMEGA-AMINOALKYL)PHENACETYL]-L-SERYL-L-LYSYL DIPEPTIDE AMIDES AS POTENT PEPTIDOMIMETIC INHIBITORS OF CANDIDA-ALBICANS AND HUMAN MYRISTOYL-COA-PROTEIN N-MYRISTOYL TRANSFERASE
Authors: NAGARAJAN SR DEVADAS B ZUPEC ME FREEMAN SK BROWN DL LU HF MEHTA PP KISHORE NS MCWHERTER CA GETMAN DP GORDON JI SIKORSKI JA
Citation: Sr. Nagarajan et al., CONFORMATIONALLY CONSTRAINED [P-(OMEGA-AMINOALKYL)PHENACETYL]-L-SERYL-L-LYSYL DIPEPTIDE AMIDES AS POTENT PEPTIDOMIMETIC INHIBITORS OF CANDIDA-ALBICANS AND HUMAN MYRISTOYL-COA-PROTEIN N-MYRISTOYL TRANSFERASE, Journal of medicinal chemistry, 40(10), 1997, pp. 1422-1438
THE RECEPTOR-BINDING SITE OF HUMAN INTERLEUKIN-3 DEFINED BY MUTAGENESIS AND MOLECULAR MODELING
Authors: KLEIN BK FENG YQ MCWHERTER CA HOOD WF PAIK K MCKEARN JP
Citation: Bk. Klein et al., THE RECEPTOR-BINDING SITE OF HUMAN INTERLEUKIN-3 DEFINED BY MUTAGENESIS AND MOLECULAR MODELING, The Journal of biological chemistry, 272(36), 1997, pp. 22630-22641
SCANNING ALANINE MUTAGENESIS AND DE-PEPTIDIZATION OF A CANDIDA-ALBICANS MYRISTOYL-COA-PROTEIN N-MYRISTOLYTRANSFERASE OCTAPEPTIDE SUBSTRATE REVEALS 3 ELEMENTS CRITICAL FOR MOLECULAR RECOGNITION
Authors: MCWHERTER CA ROCQUE WJ ZUPEC ME FREEMAN SK BROWN DL DEVADAS B GETMAN DP SIKORSKI JA GORDON JI
Citation: Ca. Mcwherter et al., SCANNING ALANINE MUTAGENESIS AND DE-PEPTIDIZATION OF A CANDIDA-ALBICANS MYRISTOYL-COA-PROTEIN N-MYRISTOLYTRANSFERASE OCTAPEPTIDE SUBSTRATE REVEALS 3 ELEMENTS CRITICAL FOR MOLECULAR RECOGNITION, The Journal of biological chemistry, 272(18), 1997, pp. 11874-11880
SELECTIVE PEPTIDIC AND PEPTIDOMIMETIC INHIBITORS OF CANDIDA-ALBICANS MYRISTOYLCOA-PROTEIN N-MYRISTOYLTRANSFERASE - A NEW APPROACH TO ANTIFUNGAL THERAPY
Authors: SIKORSKI JA DEVADAS B ZUPEC ME FREEMAN SK BROWN DL LU HF NAGARAJAN S MEHTA PP WADE AC KISHORE NS BRYANT ML GETMAN DP MCWHERTER CA GORDON JI
Citation: Ja. Sikorski et al., SELECTIVE PEPTIDIC AND PEPTIDOMIMETIC INHIBITORS OF CANDIDA-ALBICANS MYRISTOYLCOA-PROTEIN N-MYRISTOYLTRANSFERASE - A NEW APPROACH TO ANTIFUNGAL THERAPY, Biopolymers, 43(1), 1997, pp. 43-71
A CHIRAL RECOGNITION ELEMENT WITH AN UNUSUAL SIZE CONSTRAINT AFFECTS THE POTENCY AND SELECTIVITY FOR PEPTIDOMIMETIC INHIBITORS OF CANDIDA-ALBICANS MYRISTOYL-COA-PROTEIN N-MYRISTOYLTRANSFERASE
Authors: DEVADAS B FREEMAN SK MCWHERTER CA KUNEMAN DW VINJAMOORI DV SIKORSKI JA
Citation: B. Devadas et al., A CHIRAL RECOGNITION ELEMENT WITH AN UNUSUAL SIZE CONSTRAINT AFFECTS THE POTENCY AND SELECTIVITY FOR PEPTIDOMIMETIC INHIBITORS OF CANDIDA-ALBICANS MYRISTOYL-COA-PROTEIN N-MYRISTOYLTRANSFERASE, Bioorganic & medicinal chemistry letters, 6(16), 1996, pp. 1977-1982
3-DIMENSIONAL SOLUTION STRUCTURE AND BACKBONE DYNAMICS OF A VARIANT OF HUMAN INTERLEUKIN-3
Authors: FENG YP KLEIN BK MCWHERTER CA
Citation: Yp. Feng et al., 3-DIMENSIONAL SOLUTION STRUCTURE AND BACKBONE DYNAMICS OF A VARIANT OF HUMAN INTERLEUKIN-3, Journal of Molecular Biology, 259(3), 1996, pp. 524-541
LIGAND-RECEPTOR INTERACTIONS OF HIL-3 AND RELATED PROTEIN VARIANTS
Authors: KLEIN B FENG Y GRABBE E KUBICEK R HOOD WF SHIEH JJ ABEGG AL MCWHERTER CA MCKEARN JP
Citation: B. Klein et al., LIGAND-RECEPTOR INTERACTIONS OF HIL-3 AND RELATED PROTEIN VARIANTS, Blood, 88(10), 1996, pp. 2171-2171
GENETIC-STUDIES REVEAL THAT MYRISTOYLCOA-PROTEIN N-MYRISTOYLTRANSFERASE IS AN ESSENTIAL ENZYME IN CANDIDA-ALBICANS
Authors: WEINBURG RA MCWHERTER CA FREEMAN KS WOOD DC GORDON JI LEE SC
Citation: Ra. Weinburg et al., GENETIC-STUDIES REVEAL THAT MYRISTOYLCOA-PROTEIN N-MYRISTOYLTRANSFERASE IS AN ESSENTIAL ENZYME IN CANDIDA-ALBICANS, Molecular microbiology, 16(2), 1995, pp. 241-250
MODELS FOR IL-3 RECEPTOR-BINDING SITES BASED ON THE SOLUTION STRUCTURE OF AN IL-3 SYNTHOKINE
Authors: KLEIN BK FENG Y OLINS PO BAUER SC PAIK K THOMAS JW EASTON AM BRAFORDGOLDBERG S CAPARON MH MCWHERTER CA MCKEARN JP
Citation: Bk. Klein et al., MODELS FOR IL-3 RECEPTOR-BINDING SITES BASED ON THE SOLUTION STRUCTURE OF AN IL-3 SYNTHOKINE, Experimental hematology, 23(8), 1995, pp. 880-880
DESIGN AND SYNTHESES OF POTENT AND SELECTIVE DIPEPTIDE INHIBITORS OF CANDIDA-ALBICANS MYRISTOYL-COA-PROTEIN N-MYRISTOYLTRANSFERASE
Authors: DEVADAS B ZUPEC ME FREEMAN SK BROWN DL NAGARAJAN S SIKORSKI JA MCWHERTER CA GETMAN DP GORDON JI
Citation: B. Devadas et al., DESIGN AND SYNTHESES OF POTENT AND SELECTIVE DIPEPTIDE INHIBITORS OF CANDIDA-ALBICANS MYRISTOYL-COA-PROTEIN N-MYRISTOYLTRANSFERASE, Journal of medicinal chemistry, 38(11), 1995, pp. 1837-1840
H-1, C-13, AND N-15 NMR RESONANCE ASSIGNMENTS, SECONDARY STRUCTURE, AND BACKBONE TOPOLOGY OF A VARIANT OF HUMAN INTERLEUKIN-3
Authors: FENG YQ KLEIN BK VU L AYKENT S MCWHERTER CA
Citation: Yq. Feng et al., H-1, C-13, AND N-15 NMR RESONANCE ASSIGNMENTS, SECONDARY STRUCTURE, AND BACKBONE TOPOLOGY OF A VARIANT OF HUMAN INTERLEUKIN-3, Biochemistry, 34(19), 1995, pp. 6540-6551
ISOTHERMAL TITRATION CALORIMETRIC STUDIES OF SACCHAROMYCES-CEREVISIAEMYRISTOYL-COA-PROTEIN N-MYRISTOYLTRANSFERASE - DETERMINANTS OF BINDING-ENERGY AND CATALYTIC DISCRIMINATION AMONG ACYL-COA AND PEPTIDE LIGANDS
Authors: BHATNAGAR RS JACKSONMACHELSKI E MCWHERTER CA GORDON JI
Citation: Rs. Bhatnagar et al., ISOTHERMAL TITRATION CALORIMETRIC STUDIES OF SACCHAROMYCES-CEREVISIAEMYRISTOYL-COA-PROTEIN N-MYRISTOYLTRANSFERASE - DETERMINANTS OF BINDING-ENERGY AND CATALYTIC DISCRIMINATION AMONG ACYL-COA AND PEPTIDE LIGANDS, The Journal of biological chemistry, 269(15), 1994, pp. 11045-11053
A COMPARATIVE-ANALYSIS OF THE KINETIC MECHANISM AND PEPTIDE SUBSTRATE-SPECIFICITY OF HUMAN AND SACCHAROMYCES-CEREVISIAE MYRISTOYL-COA - PROTEIN N-MYRISTOYLTRANSFERASE
Authors: ROCQUE WJ MCWHERTER CA WOOD DC GORDON JI
Citation: Wj. Rocque et al., A COMPARATIVE-ANALYSIS OF THE KINETIC MECHANISM AND PEPTIDE SUBSTRATE-SPECIFICITY OF HUMAN AND SACCHAROMYCES-CEREVISIAE MYRISTOYL-COA - PROTEIN N-MYRISTOYLTRANSFERASE, The Journal of biological chemistry, 268(14), 1993, pp. 9964-9971
Risultati: 1-19 |