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Results: 1-25 | 26-32
Results: 1-25/32
INFLUENCE OF GENDER AND ACETONE PRETREATMENT ON BENZENE METABOLISM INMICE EXPOSED BY NOSE-ONLY INHALATION
Authors: KENYON EM SEATON MJ HIMMELSTEIN MW ASGHARIAN B MEDINSKY MA
Citation: Em. Kenyon et al., INFLUENCE OF GENDER AND ACETONE PRETREATMENT ON BENZENE METABOLISM INMICE EXPOSED BY NOSE-ONLY INHALATION, Journal of toxicology and environmental health. Part A, 55(6), 1998, pp. 421-443
PREDICTING THE TOXICITY OF CHEMICAL-MIXTURES
Authors: BOND JA LEAVENS TL SEATON MJ MEDINSKY MA
Citation: Ja. Bond et al., PREDICTING THE TOXICITY OF CHEMICAL-MIXTURES, Chemtech, 28(7), 1998, pp. 16-23
TOXICOLOGY AND EPIDEMIOLOGY OF 1,3-BUTADIENE
Authors: HIMMELSTEIN MW ACQUAVELLA JF RECIO L MEDINSKY MA BOND JA
Citation: Mw. Himmelstein et al., TOXICOLOGY AND EPIDEMIOLOGY OF 1,3-BUTADIENE, Critical reviews in toxicology, 27(1), 1997, pp. 1-107
PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODELING OF 1,3-BUTADIENE, 1,2-EPOXY-3-BUTENE, AND 1,2-3,4-DIEPOXYBUTANE TOXICOKINETICS IN MICE AND RATS
Authors: SWEENEY LM SCHLOSSER PM MEDINSKY MA BOND JA
Citation: Lm. Sweeney et al., PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODELING OF 1,3-BUTADIENE, 1,2-EPOXY-3-BUTENE, AND 1,2-3,4-DIEPOXYBUTANE TOXICOKINETICS IN MICE AND RATS, Carcinogenesis, 18(4), 1997, pp. 611-625
A COMPARISON OF PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODEL PREDICTIONS AND EXPERIMENTAL-DATA FOR INHALED ETHANOL IN MALE AND FEMALE B6C3F(1) MICE, F344 RATS, AND HUMANS
Authors: PASTINO GM ASGHARIAN B ROBERTS K MEDINSKY MA BOND JA
Citation: Gm. Pastino et al., A COMPARISON OF PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODEL PREDICTIONS AND EXPERIMENTAL-DATA FOR INHALED ETHANOL IN MALE AND FEMALE B6C3F(1) MICE, F344 RATS, AND HUMANS, Toxicology and applied pharmacology, 145(1), 1997, pp. 147-157
DISPOSITION OF BUTADIENE EPOXIDES IN SPRAGUE-DAWLEY RATS
Authors: VALENTINE JL BOOGAARD PJ SWEENEY LM TURNER MJ BOND JA MEDINSKY MA
Citation: Jl. Valentine et al., DISPOSITION OF BUTADIENE EPOXIDES IN SPRAGUE-DAWLEY RATS, Chemico-biological interactions, 104(2-3), 1997, pp. 103-115
THE USE OF TOXICOLOGIC DATA IN MECHANISTIC RISK ASSESSMENT - 1,3-BUTADIENE AS A CASE-STUDY
Authors: BOND JA HIMMELSTEIN MW MEDINSKY MA
Citation: Ja. Bond et al., THE USE OF TOXICOLOGIC DATA IN MECHANISTIC RISK ASSESSMENT - 1,3-BUTADIENE AS A CASE-STUDY, International archives of occupational and environmental health, 68(6), 1996, pp. 415-420
METABOLISM OF BUTADIENE BY MICE, RATS, AND HUMANS - A COMPARISON OF PHYSIOLOGICALLY-BASED TOXICOKINETIC MODEL PREDICTIONS AND EXPERIMENTAL-DATA
Authors: BOND JA HIMMELSTEIN MW SEATON M BOOGAARD P MEDINSKY MA
Citation: Ja. Bond et al., METABOLISM OF BUTADIENE BY MICE, RATS, AND HUMANS - A COMPARISON OF PHYSIOLOGICALLY-BASED TOXICOKINETIC MODEL PREDICTIONS AND EXPERIMENTAL-DATA, Toxicology, 113(1-3), 1996, pp. 48-54
PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODELING OF BLOOD AND TISSUE EPOXIDE MEASUREMENTS FOR BUTADIENE
Authors: SWEENEY LM HIMMELSTEIN MW SCHLOSSER PM MEDINSKY MA
Citation: Lm. Sweeney et al., PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODELING OF BLOOD AND TISSUE EPOXIDE MEASUREMENTS FOR BUTADIENE, Toxicology, 113(1-3), 1996, pp. 318-321
DEVELOPMENT OF A PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODEL FOR METHYL TERTIARY-BUTYL ETHER AND TERTIARY-BUTANOL IN MALE FISCHER-344 RATS
Authors: BORGHOFF SJ MURPHY JE MEDINSKY MA
Citation: Sj. Borghoff et al., DEVELOPMENT OF A PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODEL FOR METHYL TERTIARY-BUTYL ETHER AND TERTIARY-BUTANOL IN MALE FISCHER-344 RATS, Fundamental and applied toxicology, 30(2), 1996, pp. 264-275
MECHANISTIC CONSIDERATIONS IN BENZENE PHYSIOLOGICAL MODEL DEVELOPMENT
Authors: MEDINSKY MA KENYON EM SEATON MJ SCHLOSSER PM
Citation: Ma. Medinsky et al., MECHANISTIC CONSIDERATIONS IN BENZENE PHYSIOLOGICAL MODEL DEVELOPMENT, Environmental health perspectives, 104, 1996, pp. 1399-1404
REDUCTION OF BENZENE METABOLISM AND TOXICITY IN MICE THAT LACK CYP2E1EXPRESSION
Authors: VALENTINE JL LEE SST SEATON MJ ASGHARIAN B FARRIS G CORTON JC GONZALEZ FJ MEDINSKY MA
Citation: Jl. Valentine et al., REDUCTION OF BENZENE METABOLISM AND TOXICITY IN MICE THAT LACK CYP2E1EXPRESSION, Toxicology and applied pharmacology, 141(1), 1996, pp. 205-213
DIFFERENCES IN RATES OF BENZENE METABOLISM CORRELATE WITH OBSERVED GENOTOXICITY
Authors: KENYON EM KRAICHELY RE HUDSON KT MEDINSKY MA
Citation: Em. Kenyon et al., DIFFERENCES IN RATES OF BENZENE METABOLISM CORRELATE WITH OBSERVED GENOTOXICITY, Toxicology and applied pharmacology, 136(1), 1996, pp. 49-56
PHARMACOKINETIC MODELING APPROACHES FOR DESCRIBING THE UPTAKE, SYSTEMIC DISTRIBUTION, AND DISPOSITION OF INHALED CHEMICALS
Authors: GARGAS ML MEDINSKY MA ANDERSEN ME
Citation: Ml. Gargas et al., PHARMACOKINETIC MODELING APPROACHES FOR DESCRIBING THE UPTAKE, SYSTEMIC DISTRIBUTION, AND DISPOSITION OF INHALED CHEMICALS, Critical reviews in toxicology, 25(3), 1995, pp. 237-254
HEALTH RISK ASSESSMENT OF CHEMICAL-MIXTURES FROM A RESEARCH PERSPECTIVE
Authors: BOND JA MEDINSKY MA
Citation: Ja. Bond et Ma. Medinsky, HEALTH RISK ASSESSMENT OF CHEMICAL-MIXTURES FROM A RESEARCH PERSPECTIVE, Toxicology letters, 82-3, 1995, pp. 521-525
RECENT DEVELOPMENTS IN METHANOL TOXICITY
Authors: MEDINSKY MA DORMAN DC
Citation: Ma. Medinsky et Dc. Dorman, RECENT DEVELOPMENTS IN METHANOL TOXICITY, Toxicology letters, 82-3, 1995, pp. 707-711
THE APPLICATION OF PHYSIOLOGICALLY-BASED PHARMACOKINETIC PHARMACODYNAMIC (PBPK/PD) MODELING TO UNDERSTANDING THE MECHANISM OF ACTION OF HAZARDOUS SUBSTANCES/
Authors: MEDINSKY MA
Citation: Ma. Medinsky, THE APPLICATION OF PHYSIOLOGICALLY-BASED PHARMACOKINETIC PHARMACODYNAMIC (PBPK/PD) MODELING TO UNDERSTANDING THE MECHANISM OF ACTION OF HAZARDOUS SUBSTANCES/, Toxicology letters, 79(1-3), 1995, pp. 185-191
BENZENE - A CASE-STUDY IN PARENT CHEMICAL AND METABOLITE INTERACTIONS
Authors: MEDINSKY MA KENYON EM SCHLOSSER PM
Citation: Ma. Medinsky et al., BENZENE - A CASE-STUDY IN PARENT CHEMICAL AND METABOLITE INTERACTIONS, Toxicology, 105(2-3), 1995, pp. 225-233
IN-VITRO CONJUGATION OF BENZENE METABOLITES BY HUMAN LIVER - POTENTIAL INFLUENCE OF INTERINDIVIDUAL VARIABILITY ON BENZENE TOXICITY
Authors: SEATON MJ SCHLOSSER PM MEDINSKY MA
Citation: Mj. Seaton et al., IN-VITRO CONJUGATION OF BENZENE METABOLITES BY HUMAN LIVER - POTENTIAL INFLUENCE OF INTERINDIVIDUAL VARIABILITY ON BENZENE TOXICITY, Carcinogenesis, 16(7), 1995, pp. 1519-1527
DOSE-DEPENDENT, ROUTE-DEPENDENT, AND SEX-DEPENDENT URINARY-EXCRETION OF PHENOL METABOLITES IN B6C3F(1) MICE
Authors: KENYON EM SEELEY ME JANSZEN D MEDINSKY MA
Citation: Em. Kenyon et al., DOSE-DEPENDENT, ROUTE-DEPENDENT, AND SEX-DEPENDENT URINARY-EXCRETION OF PHENOL METABOLITES IN B6C3F(1) MICE, Journal of toxicology and environmental health, 44(2), 1995, pp. 219-233
AGE-RELATED-CHANGES IN BENZENE DISPOSITION IN MALE C57BL 6N MICE DESCRIBED BY A PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODEL/
Authors: MCMAHON TF MEDINSKY MA BIRNBAUM LS
Citation: Tf. Mcmahon et al., AGE-RELATED-CHANGES IN BENZENE DISPOSITION IN MALE C57BL 6N MICE DESCRIBED BY A PHYSIOLOGICALLY-BASED PHARMACOKINETIC MODEL/, Toxicology letters, 74(3), 1994, pp. 241-253
BENZENE METABOLISM BY HUMAN LIVER-MICROSOMES IN RELATION TO CYTOCHROME-P450 2E1 ACTIVITY
Authors: SEATON MJ SCHLOSSER PM BOND JA MEDINSKY MA
Citation: Mj. Seaton et al., BENZENE METABOLISM BY HUMAN LIVER-MICROSOMES IN RELATION TO CYTOCHROME-P450 2E1 ACTIVITY, Carcinogenesis, 15(9), 1994, pp. 1799-1806
IN-VIVO METABOLISM OF BUTADIENE BY MICE AND RATS - A COMPARISON OF PHYSIOLOGICAL MODEL PREDICTIONS AND EXPERIMENTAL-DATA
Authors: MEDINSKY MA LEAVENS TL CSANADY GA GARGAS ML BOND JA
Citation: Ma. Medinsky et al., IN-VIVO METABOLISM OF BUTADIENE BY MICE AND RATS - A COMPARISON OF PHYSIOLOGICAL MODEL PREDICTIONS AND EXPERIMENTAL-DATA, Carcinogenesis, 15(7), 1994, pp. 1329-1340
1,3-BUTADIENE - LINKING METABOLISM, DOSIMETRY, AND MUTATION-INDUCTION
Authors: BOND JA CSANADY GA GARGAS ML GUENGERICH FP LEAVENS T MEDINSKY MA RECIO L
Citation: Ja. Bond et al., 1,3-BUTADIENE - LINKING METABOLISM, DOSIMETRY, AND MUTATION-INDUCTION, Environmental health perspectives, 102, 1994, pp. 87-94
CRITICAL ISSUES IN BENZENE TOXICITY AND METABOLISM - THE EFFECT OF INTERACTIONS WITH OTHER ORGANIC-CHEMICALS ON RISK ASSESSMENT
Authors: MEDINSKY MA SCHLOSSER PM BOND JA
Citation: Ma. Medinsky et al., CRITICAL ISSUES IN BENZENE TOXICITY AND METABOLISM - THE EFFECT OF INTERACTIONS WITH OTHER ORGANIC-CHEMICALS ON RISK ASSESSMENT, Environmental health perspectives, 102, 1994, pp. 119-124
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