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Results: 1-11 |
Results: 11
DISTINCT MECHANISM FOR ANTIDEPRESSANT ACTIVITY BY BLOCKADE OF CENTRALSUBSTANCE-P RECEPTORS
Authors: KRAMER MS CUTLER N FEIGHNER J SHRIVASTAVA R CARMAN J SRAMEK JJ REINES SA LIU GH SNAVELY D WYATTKNOWLES E HALE JJ MILLS SG MACCOSS M SWAIN CJ HARRISON T HILL RG HEFTI F SCOLNICK EM CASCIERI MA CHICCHI GG SADOWSKI S WILLIAMS AR HEWSON L SMITH D CARLSON EJ HARGREAVES RJ RUPNIAK NMJ
Citation: Ms. Kramer et al., DISTINCT MECHANISM FOR ANTIDEPRESSANT ACTIVITY BY BLOCKADE OF CENTRALSUBSTANCE-P RECEPTORS, Science, 281(5383), 1998, pp. 1640-1645
STRUCTURAL OPTIMIZATION AFFORDING ENYL-4-(3-OXO-1,2,4-TRIAZOL-5-YL)METHYLMORPHOLINE, A POTENT, ORALLY-ACTIVE, LONG-ACTING MORPHOLINE ACETALHUMAN NK-1 RECEPTOR ANTAGONIST
Authors: HALE JJ MILLS SG MACCOSS M FINKE PE CASCIERI MA SADOWSKI S BER E CHICCHI GG KURTZ M METZGER J EIERMANN G TSOU NN TATTERSALL FD RUPNIAK NMJ WILLIAMS AR RYCROFT W HARGREAVES R MACINTYRE DE
Citation: Jj. Hale et al., STRUCTURAL OPTIMIZATION AFFORDING ENYL-4-(3-OXO-1,2,4-TRIAZOL-5-YL)METHYLMORPHOLINE, A POTENT, ORALLY-ACTIVE, LONG-ACTING MORPHOLINE ACETALHUMAN NK-1 RECEPTOR ANTAGONIST, Journal of medicinal chemistry, 41(23), 1998, pp. 4607-4614
IN-VITRO AND IN-VIVO PREDICTORS OF THE ANTIEMETIC ACTIVITY OF TACHYKININ NK1 RECEPTOR ANTAGONISTS
Authors: RUPNIAK NMJ TATTERSALL FD WILLIAMS AR RYCROFT W CARLSON EJ CASCIERI MA SADOWSKI S BER E HALE JJ MILLS SG MACCOSS M SEWARD E HUSCROFT I OWEN S SWAIN CJ HILL RG HARGREAVES RJ
Citation: Nmj. Rupniak et al., IN-VITRO AND IN-VIVO PREDICTORS OF THE ANTIEMETIC ACTIVITY OF TACHYKININ NK1 RECEPTOR ANTAGONISTS, European journal of pharmacology, 326(2-3), 1997, pp. 201-209
CHARACTERIZATION OF THE BINDING AND ACTIVITY OF A HIGH-AFFINITY, PSEUDOIRREVERSIBLE MORPHOLINO TACHYKININ NK1 RECEPTOR ANTAGONIST
Authors: CASCIERI MA BER E FONG TM HALE JJ TANG F SHIAO LL MILLS SG MACCOSS M SADOWSKI S TOTA MR STRADER CD
Citation: Ma. Cascieri et al., CHARACTERIZATION OF THE BINDING AND ACTIVITY OF A HIGH-AFFINITY, PSEUDOIRREVERSIBLE MORPHOLINO TACHYKININ NK1 RECEPTOR ANTAGONIST, European journal of pharmacology, 325(2-3), 1997, pp. 253-261
PREDICTION OF THE ANTIEMETIC ACTIVITY OF NK1 RECEPTOR ANTAGONISTS IN FERRETS BY THEIR ABILITY TO INHIBIT GR73632-INDUCED FOOT TAPPING IN GERBILS
Authors: RUPNIAK NMJ TATTERSALL FD WILLIAMS AR RYCROFT W CARLSON EJ CASCIERI MA HALE JJ MILLS SG MACCOSS M SEWARD E HUSCROFT I SWAIN CJ HILL RG HARGREAVES RJ
Citation: Nmj. Rupniak et al., PREDICTION OF THE ANTIEMETIC ACTIVITY OF NK1 RECEPTOR ANTAGONISTS IN FERRETS BY THEIR ABILITY TO INHIBIT GR73632-INDUCED FOOT TAPPING IN GERBILS, British Journal of Pharmacology, 120, 1997, pp. 363-363
PHOSPHINIC ACID INHIBITORS OF MATRIX METALLOPROTEINASES
Authors: CALDWELL CG SAHOO SP POLO SA EVERSOLE RR LANZA TJ MILLS SG NIEDZWIECKI LM IZQUIERDOMARTIN M CHANG BC HARRISON RK KUO DW LIN TY STEIN RL DURETTE PL HAGMANN WK
Citation: Cg. Caldwell et al., PHOSPHINIC ACID INHIBITORS OF MATRIX METALLOPROTEINASES, Bioorganic & medicinal chemistry letters, 6(3), 1996, pp. 323-328
NYL-4-((3-OXO-1,2,4-TRIAZOL-5-YL)METHYL)MORPHOLINE .1. A POTENT, ORALLY-ACTIVE, MORPHOLINE-BASED HUMAN NEUROKININ-1 RECEPTOR ANTAGONIST
Authors: HALE JJ MILLS SG MACCOSS M SHAH SK QI HB MATHRE DJ CASCIERI MA SADOWSKI S STRADER CD MACINTYRE DE METZGER JM
Citation: Jj. Hale et al., NYL-4-((3-OXO-1,2,4-TRIAZOL-5-YL)METHYL)MORPHOLINE .1. A POTENT, ORALLY-ACTIVE, MORPHOLINE-BASED HUMAN NEUROKININ-1 RECEPTOR ANTAGONIST, Journal of medicinal chemistry, 39(9), 1996, pp. 1760-1762
1,2,4-TRIACYLPIPERIDINE SUBSTANCE-P ANTAGONISTS - SEPARATION OF AFFINITIES FOR THE NK-1 RECEPTOR AND THE L-TYPE CALCIUM-CHANNEL
Authors: MILLS SG MACCOSS M CASCIERI MA SADOWSKI S PATEL S CHAPMAN KL HUTSON PH
Citation: Sg. Mills et al., 1,2,4-TRIACYLPIPERIDINE SUBSTANCE-P ANTAGONISTS - SEPARATION OF AFFINITIES FOR THE NK-1 RECEPTOR AND THE L-TYPE CALCIUM-CHANNEL, Bioorganic & medicinal chemistry letters, 5(6), 1995, pp. 599-604
1,2,3-TRISUBSTITUTED CYCLOHEXYL SUBSTANCE-P ANTAGONISTS - SIGNIFICANCE OF THE RING NITROGEN IN PIPERIDINE-BASED NK-1 RECEPTOR ANTAGONISTS
Authors: MILLS SG MACCOSS M UNDERWOOD D SHAH SK FINKE PE MILLER DJ BUDHU RJ CASCIERI MA SADOWSKI S STRADER CD
Citation: Sg. Mills et al., 1,2,3-TRISUBSTITUTED CYCLOHEXYL SUBSTANCE-P ANTAGONISTS - SIGNIFICANCE OF THE RING NITROGEN IN PIPERIDINE-BASED NK-1 RECEPTOR ANTAGONISTS, Bioorganic & medicinal chemistry letters, 5(13), 1995, pp. 1345-1350
CHARACTERIZATION OF THE INTERACTION OF DIACYLPIPERAZINE ANTAGONISTS WITH THE HUMAN NEUROKININ-1 RECEPTOR - IDENTIFICATION OF A COMMON BINDING-SITE FOR STRUCTURALLY DISSIMILAR ANTAGONISTS
Authors: CASCIERI MA SHIAO LL MILLS SG MACCOSS M SWAIN CJ YU H BER E SADOWSKI S WU MT STRADER CD FONG TM
Citation: Ma. Cascieri et al., CHARACTERIZATION OF THE INTERACTION OF DIACYLPIPERAZINE ANTAGONISTS WITH THE HUMAN NEUROKININ-1 RECEPTOR - IDENTIFICATION OF A COMMON BINDING-SITE FOR STRUCTURALLY DISSIMILAR ANTAGONISTS, Molecular pharmacology, 47(4), 1995, pp. 660-665
IACYLPIPERAZINE-2-(S)-[(N-AMINOALKYL)CARBOXAMIDES] AS NOVEL, POTENT SUBSTANCE-P RECEPTOR ANTAGONISTS
Authors: MILLS SG WU MT MACCOSS M BUDHU RJ DORN CP CASCIERI MA SADOWSKI S STRADER CD GREENLEE WJ
Citation: Sg. Mills et al., IACYLPIPERAZINE-2-(S)-[(N-AMINOALKYL)CARBOXAMIDES] AS NOVEL, POTENT SUBSTANCE-P RECEPTOR ANTAGONISTS, Bioorganic & medicinal chemistry letters, 3(12), 1993, pp. 2707-2712
Risultati: 1-11 |