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Results: 1-19 |
Results: 19
CELLULAR FOLATES PREVENT POLYGLUTAMATION OF 5,10-DIDEAZATETRAHYDROFOLATE - A NOVEL MECHANISM OF RESISTANCE TO FOLATE ANTIMETABOLITES
Authors: TSE A MORAN RG
Citation: A. Tse et Rg. Moran, CELLULAR FOLATES PREVENT POLYGLUTAMATION OF 5,10-DIDEAZATETRAHYDROFOLATE - A NOVEL MECHANISM OF RESISTANCE TO FOLATE ANTIMETABOLITES, The Journal of biological chemistry, 273(40), 1998, pp. 25944-25952
MUTATIONS IN THE REDUCED FOLATE CARRIER GENE WHICH CONFER DOMINANT RESISTANCE TO 5,10-DIDEAZATETRAHYDROFOLATE
Authors: TSE A BRIGLE K TAYLOR SM MORAN RG
Citation: A. Tse et al., MUTATIONS IN THE REDUCED FOLATE CARRIER GENE WHICH CONFER DOMINANT RESISTANCE TO 5,10-DIDEAZATETRAHYDROFOLATE, The Journal of biological chemistry, 273(40), 1998, pp. 25953-25960
LOCALIZATION OF THE ACTIVE-SITE OF RECOMBINANT HUMAN FOLYLPOLY-GAMMA-GLUTAMATE SYNTHETASE USING ACTIVE-SITE LABELING AND SITE-DIRECTED MUTAGENESIS
Authors: SANGHANI PC SANGHANI SP MORAN RG
Citation: Pc. Sanghani et al., LOCALIZATION OF THE ACTIVE-SITE OF RECOMBINANT HUMAN FOLYLPOLY-GAMMA-GLUTAMATE SYNTHETASE USING ACTIVE-SITE LABELING AND SITE-DIRECTED MUTAGENESIS, The FASEB journal, 11(9), 1997, pp. 1642-1642
INTRONIC POLYADENYLATION IN THE HUMAN GLYCINAMIDE RIBONUCLEOTIDE FORMYLTRANSFERASE GENE
Authors: KAN JLC MORAN RG
Citation: Jlc. Kan et Rg. Moran, INTRONIC POLYADENYLATION IN THE HUMAN GLYCINAMIDE RIBONUCLEOTIDE FORMYLTRANSFERASE GENE, Nucleic acids research, 25(15), 1997, pp. 3118-3123
TRANSCRIPTION OF THE HUMAN FOLYLPOLY-GAMMA-GLUTAMATE SYNTHETASE GENE
Authors: FREEMANTLE SJ MORAN RG
Citation: Sj. Freemantle et Rg. Moran, TRANSCRIPTION OF THE HUMAN FOLYLPOLY-GAMMA-GLUTAMATE SYNTHETASE GENE, The Journal of biological chemistry, 272(40), 1997, pp. 25373-25379
TIGHT-BINDING OF FOLATE SUBSTRATES AND INHIBITORS TO RECOMBINANT MOUSE GLYCINAMIDE RIBONUCLEOTIDE FORMYLTRANSFERASE
Authors: SANGHANI SP MORAN RG
Citation: Sp. Sanghani et Rg. Moran, TIGHT-BINDING OF FOLATE SUBSTRATES AND INHIBITORS TO RECOMBINANT MOUSE GLYCINAMIDE RIBONUCLEOTIDE FORMYLTRANSFERASE, Biochemistry, 36(34), 1997, pp. 10506-10516
A TRIBUTE TO DR GRINDEY,GERALD,BURR, 1940-1993
Authors: MIHICH E MORAN RG NICHOL CA
Citation: E. Mihich et al., A TRIBUTE TO DR GRINDEY,GERALD,BURR, 1940-1993, Investigational new drugs, 14(3), 1996, pp. 241-242
INHIBITION OF FOLYLPOLYGLUTAMATE SYNTHETASE BY SUBSTRATE-ANALOGS WITHAN ORNITHINE SIDE-CHAIN
Authors: ROSOWSKY A FORSCH RA MORAN RG
Citation: A. Rosowsky et al., INHIBITION OF FOLYLPOLYGLUTAMATE SYNTHETASE BY SUBSTRATE-ANALOGS WITHAN ORNITHINE SIDE-CHAIN, Journal of heterocyclic chemistry, 33(4), 1996, pp. 1355-1361
AUGMENTATION OF THE THERAPEUTIC ACTIVITY OF LOMETREXOL [(6-R)5,10-DIDEAZATETRAHYDROFOLATE] BY ORAL FOLIC-ACID
Authors: ALATI T WORZALLA JF SHIH C BEWLEY JR LEWIS S MORAN RG GRINDEY GB
Citation: T. Alati et al., AUGMENTATION OF THE THERAPEUTIC ACTIVITY OF LOMETREXOL [(6-R)5,10-DIDEAZATETRAHYDROFOLATE] BY ORAL FOLIC-ACID, Cancer research, 56(10), 1996, pp. 2331-2335
RESISTANCE TO TOMUDEX (ZD1694) - MULTIFACTORIAL IN HUMAN BREAST AND COLON-CARCINOMA CELL-LINES
Authors: DRAKE JC ALLEGRA CJ MORAN RG JOHNSTON PG
Citation: Jc. Drake et al., RESISTANCE TO TOMUDEX (ZD1694) - MULTIFACTORIAL IN HUMAN BREAST AND COLON-CARCINOMA CELL-LINES, Biochemical pharmacology, 51(10), 1996, pp. 1349-1355
SUBSTRATE-SPECIFICITY OF MAMMALIAN FOLYLPOLYGLUTAMATE SYNTHETASE FOR 5,10-DIDEAZATETRAHYDROFOLATE ANALOGS
Authors: HABECK LL MENDELSOHN LG SHIH C TAYLOR EC COLMAN PD GOSSETT LS LEITNER TA SCHULTZ RM ANDIS SL MORAN RG
Citation: Ll. Habeck et al., SUBSTRATE-SPECIFICITY OF MAMMALIAN FOLYLPOLYGLUTAMATE SYNTHETASE FOR 5,10-DIDEAZATETRAHYDROFOLATE ANALOGS, Molecular pharmacology, 48(2), 1995, pp. 326-333
ANALYSIS OF A MOUSE GENE ENCODING 3 STEPS OF PURINE SYNTHESIS REVEALSUSE OF AN INTRONIC POLYADENYLATION SIGNAL WITHOUT ALTERNATIVE EXON USAGE
Authors: KAN JLC MORAN RG
Citation: Jlc. Kan et Rg. Moran, ANALYSIS OF A MOUSE GENE ENCODING 3 STEPS OF PURINE SYNTHESIS REVEALSUSE OF AN INTRONIC POLYADENYLATION SIGNAL WITHOUT ALTERNATIVE EXON USAGE, The Journal of biological chemistry, 270(4), 1995, pp. 1823-1832
UPSTREAM ORGANIZATION OF AND MULTIPLE TRANSCRIPTS FROM THE HUMAN FOLYLPOLY-GAMMA-GLUTAMATE SYNTHETASE GENE
Authors: FREEMANTLE SJ TAYLOR SM KRYSTAL G MORAN RG
Citation: Sj. Freemantle et al., UPSTREAM ORGANIZATION OF AND MULTIPLE TRANSCRIPTS FROM THE HUMAN FOLYLPOLY-GAMMA-GLUTAMATE SYNTHETASE GENE, The Journal of biological chemistry, 270(16), 1995, pp. 9579-9584
STRUCTURAL ORGANIZATION OF THE HUMAN FOLYLPOLY-GAMMA-GLUTAMATE SYNTHETASE GENE - EVIDENCE FOR A SINGLE GENOMIC LOCUS
Authors: TAYLOR SM FREEMANTLE SJ MORAN RG
Citation: Sm. Taylor et al., STRUCTURAL ORGANIZATION OF THE HUMAN FOLYLPOLY-GAMMA-GLUTAMATE SYNTHETASE GENE - EVIDENCE FOR A SINGLE GENOMIC LOCUS, Cancer research, 55(24), 1995, pp. 6030-6034
A STRATEGY FOR THE DESIGN OF MEMBRANE-PERMEABLE FOLYLPOLY-GAMMA-GLUTAMATE SYNTHETASE INHIBITORS - BAY-REGION-SUBSTITUTED 2-DESAMINO-2-METHYL-5,8-DIDEAZAFOLATE ANALOGS
Authors: SANGHANI PC JACKMAN A EVANS VR THORNTON T HUGHES L CALVERT AH MORAN RG
Citation: Pc. Sanghani et al., A STRATEGY FOR THE DESIGN OF MEMBRANE-PERMEABLE FOLYLPOLY-GAMMA-GLUTAMATE SYNTHETASE INHIBITORS - BAY-REGION-SUBSTITUTED 2-DESAMINO-2-METHYL-5,8-DIDEAZAFOLATE ANALOGS, Molecular pharmacology, 45(2), 1994, pp. 341-351
5-DEAZA-7-DESMETHYLENE ANALOGS OF 5,10-METHYLENE-5,6,7,8-TETRAHYDROFOLIC ACID AND RELATED-COMPOUNDS - SYNTHESIS AND IN-VITRO BIOLOGICAL-ACTIVITY .49.
Authors: ROSOWSKY A BADER H WRIGHT JE MORAN RG
Citation: A. Rosowsky et al., 5-DEAZA-7-DESMETHYLENE ANALOGS OF 5,10-METHYLENE-5,6,7,8-TETRAHYDROFOLIC ACID AND RELATED-COMPOUNDS - SYNTHESIS AND IN-VITRO BIOLOGICAL-ACTIVITY .49., Journal of heterocyclic chemistry, 31(5), 1994, pp. 1241-1250
PHASE-I STUDY OF (6R)-5,10-DIDEAZATETRAHYDROFOLATE - A FOLATE ANTIMETABOLITE INHIBITORY TO DE-NOVO PURINE SYNTHESIS
Authors: RAY MS MUGGIA FM LEICHMAN CG GRUNBERG SM NELSON RL DYKE RW MORAN RG
Citation: Ms. Ray et al., PHASE-I STUDY OF (6R)-5,10-DIDEAZATETRAHYDROFOLATE - A FOLATE ANTIMETABOLITE INHIBITORY TO DE-NOVO PURINE SYNTHESIS, Journal of the National Cancer Institute, 85(14), 1993, pp. 1154-1159
MOUSE CDNAS ENCODING A TRIFUNCTIONAL PROTEIN OF DE-NOVO PURINE SYNTHESIS AND A RELATED SINGLE-DOMAIN GLYCINAMIDE RIBONUCLEOTIDE SYNTHETASE
Authors: KAN JLC JANNATIPOUR M TAYLOR SM MORAN RG
Citation: Jlc. Kan et al., MOUSE CDNAS ENCODING A TRIFUNCTIONAL PROTEIN OF DE-NOVO PURINE SYNTHESIS AND A RELATED SINGLE-DOMAIN GLYCINAMIDE RIBONUCLEOTIDE SYNTHETASE, Gene, 137(2), 1993, pp. 195-202
CYTOTOXICITY OF ANTIFOLATE INHIBITORS OF THYMIDYLATE AND PURINE SYNTHESIS TO WIDR COLONIC-CARCINOMA CELLS
Authors: SMITH SG LEHMAN NL MORAN RG
Citation: Sg. Smith et al., CYTOTOXICITY OF ANTIFOLATE INHIBITORS OF THYMIDYLATE AND PURINE SYNTHESIS TO WIDR COLONIC-CARCINOMA CELLS, Cancer research, 53(23), 1993, pp. 5697-5706
Risultati: 1-19 |