AAAAAA

   
Results: 1-25 | 26-31
Results: 1-25/31
O-6-ALKYLGUANINE-DNA ALKYLTRANSFERASE INACTIVATION BY ESTER PRODRUGS OF O-6-BENZYLGUANINE DERIVATIVES AND THEIR RATE OF HYDROLYSIS BY CELLULAR ESTERASES
Authors: DOLAN ME ROY SK GARBIRAS BJ HELFT P PARAS P CHAE MY MOSCHEL RC PEGG AE
Citation: Me. Dolan et al., O-6-ALKYLGUANINE-DNA ALKYLTRANSFERASE INACTIVATION BY ESTER PRODRUGS OF O-6-BENZYLGUANINE DERIVATIVES AND THEIR RATE OF HYDROLYSIS BY CELLULAR ESTERASES, Biochemical pharmacology, 55(10), 1998, pp. 1701-1709
EFFECT OF IONIC STATE OF 2'-DEOXYGUANOSINE AND SOLVENT ON ITS ARALKYLATION BY BENZYL BROMIDE
Authors: MOON KY MOSCHEL RC
Citation: Ky. Moon et Rc. Moschel, EFFECT OF IONIC STATE OF 2'-DEOXYGUANOSINE AND SOLVENT ON ITS ARALKYLATION BY BENZYL BROMIDE, Chemical research in toxicology, 11(6), 1998, pp. 696-702
PHASE-I TRIAL OF O-6-BENZYLGUANINE FOR PATIENTS UNDERGOING SURGERY FOR MALIGNANT GLIOMA
Authors: FRIEDMAN HS KOKKINAKIS DM PLUDA J FRIEDMAN AH COKGOR I HAGLUND MM ASHLEY DM RICH J DOLAN ME PEGG AE MOSCHEL RC MCLENDON RE KERBY T HERNDON JE BIGNER DD SCHOLD SC
Citation: Hs. Friedman et al., PHASE-I TRIAL OF O-6-BENZYLGUANINE FOR PATIENTS UNDERGOING SURGERY FOR MALIGNANT GLIOMA, Journal of clinical oncology, 16(11), 1998, pp. 3570-3575
COMPARISON OF MUTAGENESIS BY O-6-METHYLGUANINE AND O-6-ETHYLGUANINE AND O-4-METHYLTHYMINE IN ESCHERICHIA-COLI USING DOUBLE-STRANDED AND GAPPED PLASMIDS
Authors: PAULY GT HUGHES SH MOSCHEL RC
Citation: Gt. Pauly et al., COMPARISON OF MUTAGENESIS BY O-6-METHYLGUANINE AND O-6-ETHYLGUANINE AND O-4-METHYLTHYMINE IN ESCHERICHIA-COLI USING DOUBLE-STRANDED AND GAPPED PLASMIDS, Carcinogenesis, 19(3), 1998, pp. 457-461
REACTION OF O-6-BENZYLGUANINE-RESISTANT MUTANTS OF HUMAN O-6-ALKYLGUANINE-DNA ALKYLTRANSFERASE WITH O-6-BENZYLGUANINE IN OLIGODEOXYRIBONUCLEOTIDES
Authors: PEGG AE KANUGULA S EDARA S PAULY GT MOSCHEL RC GOODTZOVA K
Citation: Ae. Pegg et al., REACTION OF O-6-BENZYLGUANINE-RESISTANT MUTANTS OF HUMAN O-6-ALKYLGUANINE-DNA ALKYLTRANSFERASE WITH O-6-BENZYLGUANINE IN OLIGODEOXYRIBONUCLEOTIDES, The Journal of biological chemistry, 273(18), 1998, pp. 10863-10867
INTRAARTERIAL O-6-BENZYLGUANINE ENABLES THE SPECIFIC THERAPY OF NITROSOUREA-RESISTANT INTRACRANIAL HUMAN GLIOMA XENOGRAFTS IN ATHYMIC RATS WITH 1,3-BIS(2-CHLOROETHYL)-1-NITROSOUREA
Authors: KURPAD SN DOLAN ME MCLENDON RE ARCHER GE MOSCHEL RC PEGG AE BIGNER DD FRIEDMAN HS
Citation: Sn. Kurpad et al., INTRAARTERIAL O-6-BENZYLGUANINE ENABLES THE SPECIFIC THERAPY OF NITROSOUREA-RESISTANT INTRACRANIAL HUMAN GLIOMA XENOGRAFTS IN ATHYMIC RATS WITH 1,3-BIS(2-CHLOROETHYL)-1-NITROSOUREA, Cancer chemotherapy and pharmacology, 39(4), 1997, pp. 307-316
REPAIR OF O-6-BENZYLGUANINE BY THE ESCHERICHIA-COLI ADA AND OGT AND THE HUMAN O6-ALKYLGUANINE-DNA ALKYLTRANSFERASES
Authors: GOODTZOVA K KANUGULA S EDARA S PAULY GT MOSCHEL RC PEGG AE
Citation: K. Goodtzova et al., REPAIR OF O-6-BENZYLGUANINE BY THE ESCHERICHIA-COLI ADA AND OGT AND THE HUMAN O6-ALKYLGUANINE-DNA ALKYLTRANSFERASES, The Journal of biological chemistry, 272(13), 1997, pp. 8332-8339
EFFECT OF DNA ON THE INACTIVATION OF O-6-ALKYLGUANINE-DNA ALKYLTRANSFERASE BY 9-SUBSTITUTED O-6-BENZYLGUANINE DERIVATIVES
Authors: PEGG AE CHUNG L MOSCHEL RC
Citation: Ae. Pegg et al., EFFECT OF DNA ON THE INACTIVATION OF O-6-ALKYLGUANINE-DNA ALKYLTRANSFERASE BY 9-SUBSTITUTED O-6-BENZYLGUANINE DERIVATIVES, Biochemical pharmacology, 53(10), 1997, pp. 1559-1564
O-6-ETHYLGUANINE AND O-6-BENZYLGUANINE INCORPORATED SITE-SPECIFICALLYIN CODON-12 OF THE RAT H-RAS GENE INDUCE SEMI-TARGETED AS WELL AS TARGETED MUTATIONS IN RAT4 CELLS
Authors: BISHOP RE PAULY GT MOSCHEL RC
Citation: Re. Bishop et al., O-6-ETHYLGUANINE AND O-6-BENZYLGUANINE INCORPORATED SITE-SPECIFICALLYIN CODON-12 OF THE RAT H-RAS GENE INDUCE SEMI-TARGETED AS WELL AS TARGETED MUTATIONS IN RAT4 CELLS, Carcinogenesis, 17(4), 1996, pp. 849-856
PHARMACOKINETICS AND METABOLISM IN RATS OF 2,4-DIAMINO-6-BENZYLOXY-5-NITROSOPYRIMIDINE, AN INACTIVATOR OF O-6-ALKYLGUANINE-DNA ALKYLTRANSFERASE
Authors: ROY SK MOSCHEL RC DOLAN ME
Citation: Sk. Roy et al., PHARMACOKINETICS AND METABOLISM IN RATS OF 2,4-DIAMINO-6-BENZYLOXY-5-NITROSOPYRIMIDINE, AN INACTIVATOR OF O-6-ALKYLGUANINE-DNA ALKYLTRANSFERASE, Drug metabolism and disposition, 24(11), 1996, pp. 1205-1211
TREATMENT OF HUMAN BRAIN-TUMOR XENOGRAFTS WITH O-6-BENZYL-2'-DEOXYGUANOSINE AND BCNU
Authors: SCHOLD SC KOKKINAKIS DM RUDY JL MOSCHEL RC PEGG AE
Citation: Sc. Schold et al., TREATMENT OF HUMAN BRAIN-TUMOR XENOGRAFTS WITH O-6-BENZYL-2'-DEOXYGUANOSINE AND BCNU, Cancer research, 56(9), 1996, pp. 2076-2081
8-SUBSTITUTED O-6-BENZYLGUANINE, SUBSTITUTED 6(4)-(BENZYLOXY)PYRIMIDINE, AND RELATED DERIVATIVES AS INACTIVATORS OF HUMAN O-6-ALKYLGUANINE-DNA ALKYLTRANSFERASE
Authors: CHAE MY SWENN K KANUGULA S DOLAN ME PEGG AE MOSCHEL RC
Citation: My. Chae et al., 8-SUBSTITUTED O-6-BENZYLGUANINE, SUBSTITUTED 6(4)-(BENZYLOXY)PYRIMIDINE, AND RELATED DERIVATIVES AS INACTIVATORS OF HUMAN O-6-ALKYLGUANINE-DNA ALKYLTRANSFERASE, Journal of medicinal chemistry, 38(2), 1995, pp. 359-365
SPECIFIC LABELING OF O-6-ALKYLGUANINE-DNA ALKYLTRANSFERASE BY REACTION WITH O-6-(P-HYDROXY[H-3]METHYLBENZYL)GUANINE
Authors: CIOCCO GM MOSCHEL RC CHAE MY MCLAUGHLIN PJ ZAGON IS PEGG AE
Citation: Gm. Ciocco et al., SPECIFIC LABELING OF O-6-ALKYLGUANINE-DNA ALKYLTRANSFERASE BY REACTION WITH O-6-(P-HYDROXY[H-3]METHYLBENZYL)GUANINE, Cancer research, 55(18), 1995, pp. 4085-4091
MUTAGENESIS IN ESCHERICHIA-COLI BY 3 O-6-SUBSTITUTED GUANINES IN DOUBLE-STRANDED OR GAPPED PLASMIDS
Authors: PAULY GT HUGHES SH MOSCHEL RC
Citation: Gt. Pauly et al., MUTAGENESIS IN ESCHERICHIA-COLI BY 3 O-6-SUBSTITUTED GUANINES IN DOUBLE-STRANDED OR GAPPED PLASMIDS, Biochemistry, 34(27), 1995, pp. 8924-8930
HUMAN LIVER OXIDATIVE-METABOLISM OF O-6-BENZYLGUANINE
Authors: ROY SK KORZEKWA KR GONZALEZ FJ MOSCHEL RC DOLAN ME
Citation: Sk. Roy et al., HUMAN LIVER OXIDATIVE-METABOLISM OF O-6-BENZYLGUANINE, Biochemical pharmacology, 50(9), 1995, pp. 1385-1389
INCREASED KILLING OF PROSTATE, BREAST, COLON, AND LUNG-TUMOR CELLS BYTHE COMBINATION OF INACTIVATORS OF O-6-ALKYLGUANINE-DNA ALKYLTRANSFERASE AND N,N'-BIS(2-CHLOROETHYL)-N-NITROSOUREA
Authors: PEGG AE SWENN K CHAE MY DOLAN ME MOSCHEL RC
Citation: Ae. Pegg et al., INCREASED KILLING OF PROSTATE, BREAST, COLON, AND LUNG-TUMOR CELLS BYTHE COMBINATION OF INACTIVATORS OF O-6-ALKYLGUANINE-DNA ALKYLTRANSFERASE AND N,N'-BIS(2-CHLOROETHYL)-N-NITROSOUREA, Biochemical pharmacology, 50(8), 1995, pp. 1141-1148
ENHANCEMENT OF NITROSOUREA ACTIVITY IN MEDULLOBLASTOMA-MULTIFORME ANDGLIOBLASTOMA-MULTIFORME (VOL 84, PG 1926, 1992)
Authors: FRIEDMAN HS DOLAN ME MOSCHEL RC
Citation: Hs. Friedman et al., ENHANCEMENT OF NITROSOUREA ACTIVITY IN MEDULLOBLASTOMA-MULTIFORME ANDGLIOBLASTOMA-MULTIFORME (VOL 84, PG 1926, 1992), Journal of the National Cancer Institute, 86(13), 1994, pp. 1027-1027
EFFECTS OF INHIBITION OF O-6-ALKYLGUANINE-DNA ALKYLTRANSFERASE IN RATS ON CARCINOGENESIS BY METHYLNITROSOUREA AND ETHYLNITROSOUREA
Authors: LIJINSKY W PEGG AE ANVER MR MOSCHEL RC
Citation: W. Lijinsky et al., EFFECTS OF INHIBITION OF O-6-ALKYLGUANINE-DNA ALKYLTRANSFERASE IN RATS ON CARCINOGENESIS BY METHYLNITROSOUREA AND ETHYLNITROSOUREA, Japanese journal of cancer research, 85(3), 1994, pp. 226-230
METABOLISM AND DISPOSITION OF O-6-BENZYL-2'-DEOXYGUANOSINE IN SPRAGUE-DAWLEY RATS
Authors: KOKKINAKIS DM MOSCHEL RC PEGG AE DOLAN ME SCHOLD SC
Citation: Dm. Kokkinakis et al., METABOLISM AND DISPOSITION OF O-6-BENZYL-2'-DEOXYGUANOSINE IN SPRAGUE-DAWLEY RATS, Chemical research in toxicology, 7(6), 1994, pp. 762-769
BIODISTRIBUTION OF O-6-BENZYLGUANINE AND ITS EFFECTIVENESS AGAINST HUMAN BRAIN-TUMOR XENOGRAFTS WHEN GIVEN IN POLYETHYLENE-GLYCOL OR CREMOPHOR-EL
Authors: DOLAN ME PEGG AE MOSCHEL RC VISHNUVAJJALA BR FLORA KP GREVER MR FRIEDMAN HS
Citation: Me. Dolan et al., BIODISTRIBUTION OF O-6-BENZYLGUANINE AND ITS EFFECTIVENESS AGAINST HUMAN BRAIN-TUMOR XENOGRAFTS WHEN GIVEN IN POLYETHYLENE-GLYCOL OR CREMOPHOR-EL, Cancer chemotherapy and pharmacology, 35(2), 1994, pp. 121-126
SUBSTITUTED O-6-BENZYLGUANINE DERIVATIVES AND THEIR INACTIVATION OF HUMAN O-6-ALKYLGUANINE-DNA ALKYLTRANSFERASE
Authors: CHAE MY MCDOUGALL MG DOLAN ME SWENN K PEGG AE MOSCHEL RC
Citation: My. Chae et al., SUBSTITUTED O-6-BENZYLGUANINE DERIVATIVES AND THEIR INACTIVATION OF HUMAN O-6-ALKYLGUANINE-DNA ALKYLTRANSFERASE, Journal of medicinal chemistry, 37(3), 1994, pp. 342-347
METABOLISM OF O-6-BENZYLGUANINE, AN INACTIVATOR OF O-6-ALKYLGUANINE-DNA ALKYLTRANSFERASE
Authors: DOLAN ME CHAE MY PEGG AE MULLEN JH FRIEDMAN HS MOSCHEL RC
Citation: Me. Dolan et al., METABOLISM OF O-6-BENZYLGUANINE, AN INACTIVATOR OF O-6-ALKYLGUANINE-DNA ALKYLTRANSFERASE, Cancer research, 54(19), 1994, pp. 5123-5130
ELEVATED DNA-POLYMERASE-ALPHA, DNA-POLYMERASE-BETA, AND DNA TOPOISOMERASE-II IN A MELPHALAN-RESISTANT RHABDOMYOSARCOMA XENOGRAFT THAT IS CROSS-RESISTANT TO NITROSOUREAS AND TOPOTECAN
Authors: FRIEDMAN HS DOLAN ME KAUFMANN SH COLVIN OM GRIFFITH OW MOSCHEL RC SCHOLD SC BIGNER DD ALIOSMAN F
Citation: Hs. Friedman et al., ELEVATED DNA-POLYMERASE-ALPHA, DNA-POLYMERASE-BETA, AND DNA TOPOISOMERASE-II IN A MELPHALAN-RESISTANT RHABDOMYOSARCOMA XENOGRAFT THAT IS CROSS-RESISTANT TO NITROSOUREAS AND TOPOTECAN, Cancer research, 54(13), 1994, pp. 3487-3493
RESPONSE OF REPAIR-COMPETENT AND REPAIR-DEFICIENT ESCHERICHIA-COLI TO3 O-6-SUBSTITUTED GUANINES AND INVOLVEMENT OF METHYL-DIRECTED MISMATCH REPAIR IN THE PROCESSING OF O-6-METHYLGUANINE RESIDUES
Authors: PAULY GT HUGHES SH MOSCHEL RC
Citation: Gt. Pauly et al., RESPONSE OF REPAIR-COMPETENT AND REPAIR-DEFICIENT ESCHERICHIA-COLI TO3 O-6-SUBSTITUTED GUANINES AND INVOLVEMENT OF METHYL-DIRECTED MISMATCH REPAIR IN THE PROCESSING OF O-6-METHYLGUANINE RESIDUES, Biochemistry, 33(31), 1994, pp. 9169-9177
KINETICS AND MECHANISM OF THE ACID-CATALYZED HYDROLYSIS OF O6-BENZYLGUANINE
Authors: SAFADI M BINDRA DS WILLIAMS T MOSCHEL RC STELLA VJ
Citation: M. Safadi et al., KINETICS AND MECHANISM OF THE ACID-CATALYZED HYDROLYSIS OF O6-BENZYLGUANINE, International journal of pharmaceutics, 90(3), 1993, pp. 239-246
Risultati: 1-25 | 26-31