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Results: 1-22 |
Results: 22
Enzyme-induction dependent bioactivation of troglitazone and troglitazone quinone in vivo
Authors: Tettey, JN Maggs, JL Rapeport, WG Pirmohamed, M Park, BK
Citation: Jn. Tettey et al., Enzyme-induction dependent bioactivation of troglitazone and troglitazone quinone in vivo, CHEM RES T, 14(8), 2001, pp. 965-974
The problem of college drinking: Insights from a developmental perspective
Authors: Schulenberg, J Maggs, JL Long, SW Sher, KJ Gotham, HJ Baer, JS Kivlahan, DR Marlatt, GA Zucker, RA
Citation: J. Schulenberg et al., The problem of college drinking: Insights from a developmental perspective, ALC CLIN EX, 25(3), 2001, pp. 473-477
Comparison of the modulatory effects of human and rat liver microsomal metabolism on the estrogenicity of bisphenol A: Implications for extrapolationto humans
Authors: Elsby, R Maggs, JL Ashby, J Park, BK
Citation: R. Elsby et al., Comparison of the modulatory effects of human and rat liver microsomal metabolism on the estrogenicity of bisphenol A: Implications for extrapolationto humans, J PHARM EXP, 297(1), 2001, pp. 103-113
Assessment of the effects of metabolism on the estrogenic activity of xenoestrogens: A two-stage approach coupling human liver microsomes and a yeastestrogenicity assay
Authors: Elsby, R Maggs, JL Ashby, J Paton, D Sumpter, JP Park, BK
Citation: R. Elsby et al., Assessment of the effects of metabolism on the estrogenic activity of xenoestrogens: A two-stage approach coupling human liver microsomes and a yeastestrogenicity assay, J PHARM EXP, 296(2), 2001, pp. 329-337
Efficient preparations of the beta-glucuronides of dihydroartemisinin and structural confirmation of the human glucuronide metabolite
Authors: O'Neill, PM Scheinmann, F Stachulski, AV Maggs, JL Park, BK
Citation: Pm. O'Neill et al., Efficient preparations of the beta-glucuronides of dihydroartemisinin and structural confirmation of the human glucuronide metabolite, J MED CHEM, 44(9), 2001, pp. 1467-1470
Synthesis, antimalarial activity, biomimetic iron(II) chemistry, and in vivo metabolism of novel, potent C-10-phenoxy derivatives of dihydroartemisinin
Authors: O'Neill, PM Miller, A Bishop, LPD Hindley, S Maggs, JL Ward, SA Roberts, SM Scheinmann, F Stachulski, AV Posner, GH Park, BK
Citation: Pm. O'Neill et al., Synthesis, antimalarial activity, biomimetic iron(II) chemistry, and in vivo metabolism of novel, potent C-10-phenoxy derivatives of dihydroartemisinin, J MED CHEM, 44(1), 2001, pp. 58-68
Metabolism of lamotrigine to a reactive arene oxide intermediate
Authors: Maggs, JL Naisbitt, DJ Tettey, JNA Pirmohamed, M Park, BK
Citation: Jl. Maggs et al., Metabolism of lamotrigine to a reactive arene oxide intermediate, CHEM RES T, 13(11), 2000, pp. 1075-1081
Preventing alcohol misuse: The impact of refusal skills and norms
Authors: Wynn, SR Schulenberg, J Maggs, JL Zucker, RA
Citation: Sr. Wynn et al., Preventing alcohol misuse: The impact of refusal skills and norms, PSYCH ADDIC, 14(1), 2000, pp. 36-47
Major inter-species differences in the rates of O-sulphonation and O-glucuronylation of alpha-hydroxytamoxifen in vitro: a metabolic disparity protecting human liver from the formation of tamoxifen-DNA adducts
Authors: Boocock, DJ Maggs, JL Brown, K White, INH Park, BK
Citation: Dj. Boocock et al., Major inter-species differences in the rates of O-sulphonation and O-glucuronylation of alpha-hydroxytamoxifen in vitro: a metabolic disparity protecting human liver from the formation of tamoxifen-DNA adducts, CARCINOGENE, 21(10), 2000, pp. 1851-1858
Biliary metabolites of beta-artemether in rats: Biotransformations of an antimalarial endoperoxide
Authors: Maggs, JL Bishop, LPD Edwards, G O'Neill, PM Ward, SA Winstanley, PA Park, BK
Citation: Jl. Maggs et al., Biliary metabolites of beta-artemether in rats: Biotransformations of an antimalarial endoperoxide, DRUG META D, 28(2), 2000, pp. 209-217
Biomimetic Fe(II)-mediated degradation of arteflene (Ro-42-1611). The first EPR spin-trapping evidence for the previously postulated secondary carbon-centered cyclohexyl radical.
Authors: O'Neill, PM Bishop, LPD Searle, NL Maggs, JL Storr, RC Ward, SA Park, BK Mabbs, F
Citation: Pm. O'Neill et al., Biomimetic Fe(II)-mediated degradation of arteflene (Ro-42-1611). The first EPR spin-trapping evidence for the previously postulated secondary carbon-centered cyclohexyl radical., J ORG CHEM, 65(5), 2000, pp. 1578-1582
Methapyrilene hepatotoxicity is associated with increased hepatic glutathione, the formation of glucuronide conjugates, and enterohepatic recirculation
Authors: Ratra, GS Powell, CJ Park, BK Maggs, JL Cottrell, S
Citation: Gs. Ratra et al., Methapyrilene hepatotoxicity is associated with increased hepatic glutathione, the formation of glucuronide conjugates, and enterohepatic recirculation, CHEM-BIO IN, 129(3), 2000, pp. 279-295
Obstacles to the prediction of estrogenicity from chemical structure: Assay-mediated metabolic transformation and the apparent promiscuous nature of the estrogen receptor
Authors: Elsby, R Ashby, J Sumpter, JP Brooks, AN Pennie, WD Maggs, JL Lefevre, PA Odum, J Beresford, N Paton, D Park, BK
Citation: R. Elsby et al., Obstacles to the prediction of estrogenicity from chemical structure: Assay-mediated metabolic transformation and the apparent promiscuous nature of the estrogen receptor, BIOCH PHARM, 60(10), 2000, pp. 1519-1530
Adolescents' subjective age: An indicator of perceived maturity
Authors: Galambos, NL Kolaric, GC Sears, HA Maggs, JL
Citation: Nl. Galambos et al., Adolescents' subjective age: An indicator of perceived maturity, J RES ADOLE, 9(3), 1999, pp. 309-337
Glucuronylation of alpha-hydroxytamoxifen: a deactivation pathway in humans?
Authors: Boocock, DJ Maggs, JL Brown, K White, INH Park, BK
Citation: Dj. Boocock et al., Glucuronylation of alpha-hydroxytamoxifen: a deactivation pathway in humans?, BR J CL PH, 47(5), 1999, pp. 578-579
A possible role for metabolism in modulating the oestrogenic activity of xenoestrogens measured by the rodent uterotrophic assay
Authors: Elsby, R Maggs, JL Ashby, J Park, BK
Citation: R. Elsby et al., A possible role for metabolism in modulating the oestrogenic activity of xenoestrogens measured by the rodent uterotrophic assay, BR J CL PH, 47(5), 1999, pp. 589-589
On peer influences to get drunk: A panel study of young adolescents
Authors: Schulenberg, J Maggs, JL Dielman, TE Leech, SL Kloska, DD Shope, JT Laetz, VB
Citation: J. Schulenberg et al., On peer influences to get drunk: A panel study of young adolescents, MERRILL-PAL, 45(1), 1999, pp. 108-142
alpha-hydroxytamoxifen, a genotoxic metabolite of tamoxifen in the rat: identification and quantification in vivo and in vitro
Authors: Boocock, DJ Maggs, JL White, INH Park, BK
Citation: Dj. Boocock et al., alpha-hydroxytamoxifen, a genotoxic metabolite of tamoxifen in the rat: identification and quantification in vivo and in vitro, CARCINOGENE, 20(1), 1999, pp. 153-160
Metabolism of the antimalarial endoperoxide Ro 42-1611 (arteflene) in the rat: Evidence for endoperoxide bioactivation
Authors: Bishop, LPD Maggs, JL O'Neill, PM Park, BK
Citation: Lpd. Bishop et al., Metabolism of the antimalarial endoperoxide Ro 42-1611 (arteflene) in the rat: Evidence for endoperoxide bioactivation, J PHARM EXP, 289(1), 1999, pp. 511-520
Novel, potent, semisynthetic antimalarial carba analogues of the first-generation 1,2,4-trioxane artemether
Authors: O'Neill, PM Searle, NL Kan, KW Storr, RC Maggs, JL Ward, SA Raynes, K Park, BK
Citation: Pm. O'Neill et al., Novel, potent, semisynthetic antimalarial carba analogues of the first-generation 1,2,4-trioxane artemether, J MED CHEM, 42(26), 1999, pp. 5487-5493
Metabolism-dependent neutrophil cytotoxicity of amodiaquine: A comparison with pyronaridine and related antimalarial drugs
Authors: Naisbitt, DJ Williams, DP O'Neill, PM Maggs, JL Willock, DJ Pirmohamed, M Park, BK
Citation: Dj. Naisbitt et al., Metabolism-dependent neutrophil cytotoxicity of amodiaquine: A comparison with pyronaridine and related antimalarial drugs, CHEM RES T, 11(12), 1998, pp. 1586-1595
Safety assessment of peroxide antimalarials: clinical and chemical perspectives
Authors: Park, BK O'Neill, PM Maggs, JL Pirmohamed, M
Citation: Bk. Park et al., Safety assessment of peroxide antimalarials: clinical and chemical perspectives, BR J CL PH, 46(6), 1998, pp. 521-529
Risultati: 1-22 |