AAAAAA

   
Results: 1-7 |
Results: 7
Design and synthesis of a series of (2R)-N-4-hydroxy-2-(3-hydroxybenzyl)-N-1-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]butanediamide derivatives as potent, selective, and orally bioavailable aggrecanase inhibitors
Authors: Yao, WQ Wasserman, ZR Chao, M Reddy, G Shi, E Liu, RQ Covington, MB Arner, EC Pratta, MA Tortorella, M Magolda, RL Newton, R Qian, MX Ribadeneira, MD Christ, D Wexler, RR Decicco, CP
Citation: Wq. Yao et al., Design and synthesis of a series of (2R)-N-4-hydroxy-2-(3-hydroxybenzyl)-N-1-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]butanediamide derivatives as potent, selective, and orally bioavailable aggrecanase inhibitors, J MED CHEM, 44(21), 2001, pp. 3347-3350
Discovery of macrocyclic hydroxamic acids containing biphenylmethyl derivatives at P1 ', a series of selective TNF-alpha converting enzyme inhibitorswith potent cellular activity in the inhibition of TNF-alpha release
Authors: Xue, CB He, XH Corbett, RL Roderick, J Wasserman, ZR Liu, RQ Jaffee, BD Covington, MB Qian, MX Trzaskos, JM Newton, RC Magolda, RL Wexler, RR Decicco, CP
Citation: Cb. Xue et al., Discovery of macrocyclic hydroxamic acids containing biphenylmethyl derivatives at P1 ', a series of selective TNF-alpha converting enzyme inhibitorswith potent cellular activity in the inhibition of TNF-alpha release, J MED CHEM, 44(21), 2001, pp. 3351-3354
Design, synthesis, and structure-activity relationships of macrocyclic hydroxamic acids that inhibit tumor necrosis factor alpha release in vitro andin vivo
Authors: Xue, CB Voss, ME Nelson, DJ Duan, JJW Cherney, RJ Jacobson, IC He, XH Roderick, J Chen, LH Corbett, RL Wang, L Meyer, DT Kennedy, K DeGrado, WF Hardman, KD Teleha, CA Jaffee, BD Liu, RQ Copeland, RA Covington, MB Christ, DD Trzaskos, JM Newton, RC Magolda, RL Wexler, RR Decicco, CP
Citation: Cb. Xue et al., Design, synthesis, and structure-activity relationships of macrocyclic hydroxamic acids that inhibit tumor necrosis factor alpha release in vitro andin vivo, J MED CHEM, 44(16), 2001, pp. 2636-2660
Inhibition of MAP kinase kinase (MEK) results in an anti-inflammatory response in vivo
Authors: Jaffee, BD Manos, EJ Collins, RJ Czerniak, PM Favata, MF Magolda, RL Scherle, PA Trzaskos, JM
Citation: Bd. Jaffee et al., Inhibition of MAP kinase kinase (MEK) results in an anti-inflammatory response in vivo, BIOC BIOP R, 268(2), 2000, pp. 647-651
Terphenyl cyclooxygenase-2 (COX-2) inhibitors: Optimization of the centralring and o-biphenyl analogs
Authors: Pinto, DJP Batt, DG Pitts, WJ Petraitis, JJ Orwat, MJ Wang, SG Jetter, JW Sherk, SR Houghton, GC Copeland, RA Covington, MB Trzaskos, JM Magolda, RL
Citation: Djp. Pinto et al., Terphenyl cyclooxygenase-2 (COX-2) inhibitors: Optimization of the centralring and o-biphenyl analogs, BIOORG MED, 9(7), 1999, pp. 919-924
Purification and cloning of aggrecanase-1: A member of the ADAMTS family of proteins
Authors: Tortorella, MD Burn, TC Pratta, MA Abbaszade, I Hollis, JM Liu, R Rosenfeld, SA Copeland, RA Decicco, CP Wynn, R Rockwell, A Yang, F Duke, JL Solomon, K George, H Bruckner, R Nagase, H Itoh, Y Ellis, DM Ross, H Wiswall, BH Murphy, K Hillman, MC Hollis, GF Newton, RC Magolda, RL Trzaskos, JM Arner, EC
Citation: Md. Tortorella et al., Purification and cloning of aggrecanase-1: A member of the ADAMTS family of proteins, SCIENCE, 284(5420), 1999, pp. 1664-1666
Cloning and characterization of ADAMTS11, an aggrecanase from the ADAMTS family
Authors: Abbaszade, I Liu, RQ Yang, F Rosenfeld, SA Ross, OH Link, JR Ellis, DM Tortorella, MD Pratta, MA Hollis, JM Wynn, R Duke, JL George, HJ Hillman, MC Murphy, K Wiswall, BH Copeland, RA Decicco, CP Bruckner, R Nagase, H Itoh, Y Newton, RC Magolda, RL Trzaskos, JM Hollis, GF Arner, EC Burn, TC
Citation: I. Abbaszade et al., Cloning and characterization of ADAMTS11, an aggrecanase from the ADAMTS family, J BIOL CHEM, 274(33), 1999, pp. 23443-23450
Risultati: 1-7 |