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Results: 1-25 | 26-30
Results: 1-25/30
Prospects for prevention and treatment of cancer with selective PPAR gammamodulators (SPARMs)
Authors: Sporn, MB Suh, N Mangelsdorf, DJ
Citation: Mb. Sporn et al., Prospects for prevention and treatment of cancer with selective PPAR gammamodulators (SPARMs), TRENDS MO M, 7(9), 2001, pp. 395-400
Nuclear receptors and lipid physiology: Opening the X-files
Authors: Chawla, A Repa, JJ Evans, RM Mangelsdorf, DJ
Citation: A. Chawla et al., Nuclear receptors and lipid physiology: Opening the X-files, SCIENCE, 294(5548), 2001, pp. 1866-1870
Reduction of atherosclerosis in apolipoprotein E knockout mice by activation of the retinoid X receptor
Authors: Claudel, T Leibowitz, MD Fievet, C Tailleux, A Wagner, B Repa, JJ Torpier, G Lobaccaro, JM Paterniti, JR Mangelsdorf, DJ Heyman, RA Auwerx, J
Citation: T. Claudel et al., Reduction of atherosclerosis in apolipoprotein E knockout mice by activation of the retinoid X receptor, P NAS US, 98(5), 2001, pp. 2610-2615
LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes
Authors: Laffitte, BA Repa, JJ Joseph, SB Wilpiltz, DC Kast, HR Mangelsdorf, DJ Tontonoz, P
Citation: Ba. Laffitte et al., LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes, P NAS US, 98(2), 2001, pp. 507-512
Regulation of lipoprotein lipase by the oxysterol receptors, LXR alpha andLXR beta
Authors: Zhang, Y Repa, JJ Gauthier, K Mangelsdorf, DJ
Citation: Y. Zhang et al., Regulation of lipoprotein lipase by the oxysterol receptors, LXR alpha andLXR beta, J BIOL CHEM, 276(46), 2001, pp. 43018-43024
Orphan nuclear receptors as eLiXiRs and FiXeRs of sterol metabolism
Authors: Lu, TT Repa, JJ Mangelsdorf, DJ
Citation: Tt. Lu et al., Orphan nuclear receptors as eLiXiRs and FiXeRs of sterol metabolism, J BIOL CHEM, 276(41), 2001, pp. 37735-37738
Human bile salt export pump promoter is transactivated by the farnesoid X receptor/bile acid receptor
Authors: Ananthanarayanan, M Balasubramanian, N Makishima, M Mangelsdorf, DJ Suchy, FJ
Citation: M. Ananthanarayanan et al., Human bile salt export pump promoter is transactivated by the farnesoid X receptor/bile acid receptor, J BIOL CHEM, 276(31), 2001, pp. 28857-28865
The orphan nuclear receptor, shp, mediates bile acid-induced inhibition ofthe rat bile acid transporter, ntcp
Authors: Denson, LA Sturm, E Echevarria, W Zimmerman, TL Makishima, M Mangelsdorf, DJ Karpen, SJ
Citation: La. Denson et al., The orphan nuclear receptor, shp, mediates bile acid-induced inhibition ofthe rat bile acid transporter, ntcp, GASTROENTY, 121(1), 2001, pp. 140-147
Regulation of lipid metabolism by the orphan nuclear receptors
Authors: Lobaccaro, JMA Repa, JJ Lu, TT Caira, F Henry-Berger, J Volle, DH Mangelsdorf, DJ
Citation: Jma. Lobaccaro et al., Regulation of lipid metabolism by the orphan nuclear receptors, ANN ENDOCR, 62(4), 2001, pp. 239-247
Engineering orthogonal ligand-receptor pairs from "near drugs"
Authors: Doyle, DF Braasch, DA Jackson, LK Weiss, HE Boehm, MF Mangelsdorf, DJ Corey, DR
Citation: Df. Doyle et al., Engineering orthogonal ligand-receptor pairs from "near drugs", J AM CHEM S, 123(46), 2001, pp. 11367-11371
Modifying ligand specificity of gene regulatory proteins
Authors: Doyle, DF Mangelsdorf, DJ Corey, DR
Citation: Df. Doyle et al., Modifying ligand specificity of gene regulatory proteins, CURR OP C B, 4(1), 2000, pp. 60-63
Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors
Authors: Lu, TT Makishima, M Repa, JJ Schoonjans, K Kerr, TA Auwerx, J Mangelsdorf, DJ
Citation: Tt. Lu et al., Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors, MOL CELL, 6(3), 2000, pp. 507-515
The role of orphan nuclear receptors in the regulation of cholesterol homeostasis
Authors: Repa, JJ Mangelsdorf, DJ
Citation: Jj. Repa et Dj. Mangelsdorf, The role of orphan nuclear receptors in the regulation of cholesterol homeostasis, ANN R C DEV, 16, 2000, pp. 459-481
Transcriptional activation of the Drosophila ecdysone receptor by insect and plant ecdysteroids
Authors: Baker, KD Warren, JT Thummel, CS Gilbert, LI Mangelsdorf, DJ
Citation: Kd. Baker et al., Transcriptional activation of the Drosophila ecdysone receptor by insect and plant ecdysteroids, INSEC BIO M, 30(11), 2000, pp. 1037-1043
Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXR alpha and LXR beta
Authors: Repa, JJ Liang, GS Ou, JF Bashmakov, Y Lobaccaro, JMA Shimomura, I Shan, B Brown, MS Goldstein, JL Mangelsdorf, DJ
Citation: Jj. Repa et al., Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXR alpha and LXR beta, GENE DEV, 14(22), 2000, pp. 2819-2830
Role of LXRs in control of lipogenesis
Authors: Schultz, JR Tu, H Luk, A Repa, JJ Medina, JC Li, LP Schwendner, S Wang, S Thoolen, M Mangelsdorf, DJ Lustig, KD Shan, B
Citation: Jr. Schultz et al., Role of LXRs in control of lipogenesis, GENE DEV, 14(22), 2000, pp. 2831-2838
A synthetic triterpenoid, 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO), is a ligand for the peroxisome proliferator-activated receptor gamma
Authors: Wang, YP Porter, WW Suh, NJ Honda, T Gribble, GW Leesnitzer, LM Plunket, KD Mangelsdorf, DJ Blanchard, SG Willson, TM Sporn, MB
Citation: Yp. Wang et al., A synthetic triterpenoid, 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO), is a ligand for the peroxisome proliferator-activated receptor gamma, MOL ENDOCR, 14(10), 2000, pp. 1550-1556
Hepatocyte-specific mutation establishes retinoid X receptor alpha as a heterodimeric integrator of multiple physiological processes in the liver
Authors: Wan, YJY An, DS Cai, Y Repa, JJ Chen, THP Flores, M Postic, C Magnuson, MA Chen, J Chien, KR French, S Mangelsdorf, DJ Sucov, HM
Citation: Yjy. Wan et al., Hepatocyte-specific mutation establishes retinoid X receptor alpha as a heterodimeric integrator of multiple physiological processes in the liver, MOL CELL B, 20(12), 2000, pp. 4436-4444
Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers
Authors: Repa, JJ Turley, SD Lobaccaro, JMA Medina, J Li, L Lustig, K Shan, B Heyman, RA Dietschy, JM Mangelsdorf, DJ
Citation: Jj. Repa et al., Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers, SCIENCE, 289(5484), 2000, pp. 1524-1529
Oxysterols induce differentiation in human keratinocytes and increase Ap-1-dependent involucrin transcription
Authors: Hanley, K Ng, DC He, SS Lau, P Min, K Elias, PM Bikle, DD Mangelsdorf, DJ Williams, ML Feingold, KR
Citation: K. Hanley et al., Oxysterols induce differentiation in human keratinocytes and increase Ap-1-dependent involucrin transcription, J INVES DER, 114(3), 2000, pp. 545-553
Stress pathway activation induces phosphorylation of retinoid X receptor
Authors: Lee, HY Suh, YA Robinson, MJ Clifford, JL Hong, WK Woodgett, JR Cobb, MH Mangelsdorf, DJ Kurie, JM
Citation: Hy. Lee et al., Stress pathway activation induces phosphorylation of retinoid X receptor, J BIOL CHEM, 275(41), 2000, pp. 32193-32199
Human white/murine ABC8 mRNA levels are highly induced in lipid-loaded macrophages - A transcriptional role for specific oxysterols
Authors: Venkateswaran, A Repa, JJ Lobaccaro, JMA Bronson, A Mangelsdorf, DJ Edwards, PA
Citation: A. Venkateswaran et al., Human white/murine ABC8 mRNA levels are highly induced in lipid-loaded macrophages - A transcriptional role for specific oxysterols, J BIOL CHEM, 275(19), 2000, pp. 14700-14707
Interleukin-1 beta suppresses retinoid transactivation of two hepatic transporter genes involved in bile formation
Authors: Denson, LA Auld, KL Schiek, DS McClure, MH Mangelsdorf, DJ Karpen, SJ
Citation: La. Denson et al., Interleukin-1 beta suppresses retinoid transactivation of two hepatic transporter genes involved in bile formation, J BIOL CHEM, 275(12), 2000, pp. 8835-8843
Nuclear receptor regulation of cholesterol and bile acid metabolism
Authors: Repa, JJ Mangelsdorf, DJ
Citation: Jj. Repa et Dj. Mangelsdorf, Nuclear receptor regulation of cholesterol and bile acid metabolism, CURR OPIN B, 10(6), 1999, pp. 557-563
All-trans-retinoic acid inhibits Jun N-terminal kinase by increasing dual-specificity phosphatase activity
Authors: Lee, HY Sueoka, N Hong, WK Mangelsdorf, DJ Claret, FX Kurie, JM
Citation: Hy. Lee et al., All-trans-retinoic acid inhibits Jun N-terminal kinase by increasing dual-specificity phosphatase activity, MOL CELL B, 19(3), 1999, pp. 1973-1980
Risultati: 1-25 | 26-30