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Metal binding and radical generation of proteins in human neurological diseases and aging
Authors: Multhaup, G Masters, CL
Citation: G. Multhaup et Cl. Masters, Metal binding and radical generation of proteins in human neurological diseases and aging, METAL IONS, 36, 1999, pp. 365-387
Surgical treatment and risk of sporadic Creutzfeldt-Jakob disease: a case-control study
Authors: Collins, S Law, MG Fletcher, A Boyd, A Kaldor, J Masters, CL
Citation: S. Collins et al., Surgical treatment and risk of sporadic Creutzfeldt-Jakob disease: a case-control study, LANCET, 353(9154), 1999, pp. 693-697
Mitochondrial respiratory chain activity in the human brain as a function of age
Authors: Ojaimi, J Masters, CL Opeskin, K McKelvie, P Byrne, E
Citation: J. Ojaimi et al., Mitochondrial respiratory chain activity in the human brain as a function of age, MECH AGE D, 111(1), 1999, pp. 39-47
Prion biology and diseases
Authors: Masters, CL
Citation: Cl. Masters, Prion biology and diseases, NATURE, 402(6762), 1999, pp. 581-582
Mechanism of the cleavage specificity of Alzheimer's disease gamma-secretase identified by phenylalanine-scanning mutagenesis of the transmembrane domain of the amyloid precursor protein
Authors: Lichtenthaler, SF Wang, R Grimm, H Uljon, SN Masters, CL Beyreuther, K
Citation: Sf. Lichtenthaler et al., Mechanism of the cleavage specificity of Alzheimer's disease gamma-secretase identified by phenylalanine-scanning mutagenesis of the transmembrane domain of the amyloid precursor protein, P NAS US, 96(6), 1999, pp. 3053-3058
The hydrophobic core sequence modulates the neurotoxic and secondary structure properties of the prion peptide 106-126
Authors: Jobling, MF Stewart, LR White, AR McLean, C Friedhuber, A Maher, F Beyreuther, K Masters, CL Barrow, CJ Collins, SJ Cappai, R
Citation: Mf. Jobling et al., The hydrophobic core sequence modulates the neurotoxic and secondary structure properties of the prion peptide 106-126, J NEUROCHEM, 73(4), 1999, pp. 1557-1565
Alzheimer's disease: Correlation of the suppression of beta-amyloid peptide secretion from cultured cells with inhibition of the chymotrypsin-like activity of the proteasome
Authors: Christie, G Markwell, RE Gray, CW Smith, L Godfrey, F Mansfield, F Wadsworth, H King, R McLaughlin, M Cooper, DG Ward, RV Howlett, DR Hartmann, T Lichtenthaler, SF Beyreuther, K Underwood, J Gribble, SK Cappai, R Masters, CL Tamaoka, A Gardner, RL Rivett, AJ Karran, EH Allsop, D
Citation: G. Christie et al., Alzheimer's disease: Correlation of the suppression of beta-amyloid peptide secretion from cultured cells with inhibition of the chymotrypsin-like activity of the proteasome, J NEUROCHEM, 73(1), 1999, pp. 195-204
Intracellular accumulation of detergent-soluble amyloidogenic A beta fragment of Alzheimer's disease precursor protein in the hippocampus of aged transgenic mice
Authors: Li, QX Maynard, C Cappai, R McLean, CA Cherny, RA Lynch, T Culvenor, JG Trevaskis, J Tanner, JE Bailey, KA Czech, C Bush, AI Beyreuther, K Masters, CL
Citation: Qx. Li et al., Intracellular accumulation of detergent-soluble amyloidogenic A beta fragment of Alzheimer's disease precursor protein in the hippocampus of aged transgenic mice, J NEUROCHEM, 72(6), 1999, pp. 2479-2487
Exacerbation of copper toxicity in primary neuronal cultures depleted of cellular glutathione
Authors: White, AR Bush, AI Beyreuther, K Masters, CL Cappai, R
Citation: Ar. White et al., Exacerbation of copper toxicity in primary neuronal cultures depleted of cellular glutathione, J NEUROCHEM, 72(5), 1999, pp. 2092-2098
Proteolytic fragments of Alzheimer's disease-associated presenilin 1 are present in synaptic organelles and growth cone membranes of rat brain
Authors: Beher, D Elle, C Underwood, J Davis, JB Ward, R Karran, E Masters, CL Beyreuther, K Multhaup, G
Citation: D. Beher et al., Proteolytic fragments of Alzheimer's disease-associated presenilin 1 are present in synaptic organelles and growth cone membranes of rat brain, J NEUROCHEM, 72(4), 1999, pp. 1564-1573
Proteolytic processing of the Alzheimer's disease amyloid precursor protein within its cytoplasmic domain by caspase-like proteases
Authors: Weidemann, A Paliga, K Durrwang, U Reinhard, FBM Schuckert, O Evin, G Masters, CL
Citation: A. Weidemann et al., Proteolytic processing of the Alzheimer's disease amyloid precursor protein within its cytoplasmic domain by caspase-like proteases, J BIOL CHEM, 274(9), 1999, pp. 5823-5829
Cu(II) potentiation of Alzheimer A beta neurotoxicity - Correlation with cell-free hydrogen peroxide production and metal reduction
Authors: Huang, XD Cuajungco, MP Atwood, CS Hartshorn, MA Tyndall, JDA Hanson, GR Stokes, KC Leopold, M Multhaup, G Goldstein, LE Scarpa, RC Saunders, AJ Lim, J Moir, RD Glabe, C Bowden, EF Masters, CL Fairlie, DP Tanzi, RE Bush, AI
Citation: Xd. Huang et al., Cu(II) potentiation of Alzheimer A beta neurotoxicity - Correlation with cell-free hydrogen peroxide production and metal reduction, J BIOL CHEM, 274(52), 1999, pp. 37111-37116
Aqueous dissolution of Alzheimer's disease A beta amyloid deposits by biometal depletion
Authors: Cherny, RA Legg, JT McLean, CA Fairlie, DP Huang, XD Atwood, CS Beyreuther, K Tanzi, RE Masters, CL Bush, AI
Citation: Ra. Cherny et al., Aqueous dissolution of Alzheimer's disease A beta amyloid deposits by biometal depletion, J BIOL CHEM, 274(33), 1999, pp. 23223-23228
A novel substrate for analyzing Alzheimer's disease gamma-secretase
Authors: Lichtenthaler, SF Multhaup, G Masters, CL Beyreuther, K
Citation: Sf. Lichtenthaler et al., A novel substrate for analyzing Alzheimer's disease gamma-secretase, FEBS LETTER, 453(3), 1999, pp. 288-292
Recombinant human amyloid precursor-like protein 2 (APLP2) expressed in the yeast Pichia pastoris can stimulate neurite outgrowth
Authors: Cappai, R Mok, SS Galatis, D Tucker, DF Henry, A Beyreuther, K Small, DH Masters, CL
Citation: R. Cappai et al., Recombinant human amyloid precursor-like protein 2 (APLP2) expressed in the yeast Pichia pastoris can stimulate neurite outgrowth, FEBS LETTER, 442(1), 1999, pp. 95-98
The amyloid beta-protein precursor of Alzheimer's disease is degraded extracellularly by a Kunitz protease inhibitor domain-sensitive trypsin-like serine protease in cultures of chick sympathetic neurons
Authors: Caswell, MD San Mok, S Henry, A Cappai, R Klug, G Beyreuther, K Masters, CL Small, DH
Citation: Md. Caswell et al., The amyloid beta-protein precursor of Alzheimer's disease is degraded extracellularly by a Kunitz protease inhibitor domain-sensitive trypsin-like serine protease in cultures of chick sympathetic neurons, EUR J BIOCH, 266(2), 1999, pp. 509-516
Copper levels are increased in the cerebral cortex and liver of APP and APLP2 knockout mice
Authors: White, AR Reyes, R Mercer, JFB Camakaris, J Zheng, H Bush, AI Multhaup, G Beyreuther, K Masters, CL Cappai, R
Citation: Ar. White et al., Copper levels are increased in the cerebral cortex and liver of APP and APLP2 knockout mice, BRAIN RES, 842(2), 1999, pp. 439-444
Familial prion disease mutation alters the secondary structure of recombinant mouse prion protein: Implications for the mechanism of prion formation
Authors: Cappai, R Stewart, L Jobling, MF Thyer, JM White, AR Beyreuther, K Collins, SJ Masters, CL Barrow, CJ
Citation: R. Cappai et al., Familial prion disease mutation alters the secondary structure of recombinant mouse prion protein: Implications for the mechanism of prion formation, BIOCHEM, 38(11), 1999, pp. 3280-3284
Neurobiology of primary dementia
Authors: Masters, CL
Citation: Cl. Masters, Neurobiology of primary dementia, AUST NZ J P, 33(2), 1999, pp. 297-298
Prion protein-deficient neurons reveal lower glutathione reductase activity and increased susceptibility to hydrogen peroxide toxicity
Authors: White, AR Collins, SJ Maher, F Jobling, MF Stewart, LR Thyer, JM Beyreuther, K Masters, CL Cappai, R
Citation: Ar. White et al., Prion protein-deficient neurons reveal lower glutathione reductase activity and increased susceptibility to hydrogen peroxide toxicity, AM J PATH, 155(5), 1999, pp. 1723-1730
Non-A beta component of Alzheimer's disease amyloid (NAC) revisited - NAC and alpha-synuclein are not associated with A beta amyloid
Authors: Culvenor, JG McLean, CA Cutt, S Campbell, BCV Maher, F Jakala, P Hartmann, T Beyreuther, K Masters, CL Li, QX
Citation: Jg. Culvenor et al., Non-A beta component of Alzheimer's disease amyloid (NAC) revisited - NAC and alpha-synuclein are not associated with A beta amyloid, AM J PATH, 155(4), 1999, pp. 1173-1181
Cleavage of the Alzheimer's disease amyloid precursor protein during apoptosis by activated caspases
Authors: Weidemann, A Paliga, K Durrwang, U Reinhard, FBM Evin, G Masters, CL Beyreuther, K
Citation: A. Weidemann et al., Cleavage of the Alzheimer's disease amyloid precursor protein during apoptosis by activated caspases, ALZHEIMER'S DISEASE AND RELATED DISORDERS, 1999, pp. 391-396
Characterization of gamma-secretase candidates from human brain using a new Western blot assay
Authors: Evin, G Reed, G Tanner, JE Li, QX Culvenor, JG Fuller, SJ Wadsworth, H Allsop, D Ward, RV Karran, EH Gray, CW Hartmann, T Lichtenthaler, SF Weidemann, A Beyreuther, K Masters, CL
Citation: G. Evin et al., Characterization of gamma-secretase candidates from human brain using a new Western blot assay, ALZHEIMER'S DISEASE AND RELATED DISORDERS, 1999, pp. 411-417
Oxidative stress in Alzheimer's disease
Authors: Multhaup, G Masters, CL Beyreuther, K
Citation: G. Multhaup et al., Oxidative stress in Alzheimer's disease, ALZHEIM REP, 1(3), 1998, pp. 147-154
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