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Results: 1-12 |
Results: 12
Thrombin receptor (PAR-1) antagonists. Solid-phase synthesis of indole-based peptide mimetics by anchoring to a secondary amide
Authors: Zhang, HC McComsey, DF White, KB Addo, MF Andrade-Gordon, P Derian, CK Oksenberg, D Maryanoff, BE
Citation: Hc. Zhang et al., Thrombin receptor (PAR-1) antagonists. Solid-phase synthesis of indole-based peptide mimetics by anchoring to a secondary amide, BIOORG MED, 11(16), 2001, pp. 2105-2109
Administration of a potent antagonist of protease-activated receptor-1 (PAR-1) attenuates vascular restenosis following balloon angioplasty in rats
Authors: Andrade-Gordon, P Derian, CK Maryanoff, BE Zhang, HC Addo, MF Cheung, WM Damiano, BP D'Andrea, MR Darrow, AL De Garavilla, L Eckardt, AJ Giardino, EC Haertlein, BJ McComsey, DF
Citation: P. Andrade-gordon et al., Administration of a potent antagonist of protease-activated receptor-1 (PAR-1) attenuates vascular restenosis following balloon angioplasty in rats, J PHARM EXP, 298(1), 2001, pp. 34-42
Discovery and optimization of a novel series of thrombin receptor (PAR-1) antagonists: Potent, selective peptide mimetics based on indole and indazole templates
Authors: Zhang, HC Derian, CK Andrade-Gordon, P Hoekstra, WJ McComsey, DF White, KB Poulter, BL Addo, MF Cheung, WM Damiano, BP Oksenberg, D Reynolds, EE Pandey, A Scarborough, RM Maryanoff, BE
Citation: Hc. Zhang et al., Discovery and optimization of a novel series of thrombin receptor (PAR-1) antagonists: Potent, selective peptide mimetics based on indole and indazole templates, J MED CHEM, 44(7), 2001, pp. 1021-1024
Protease-activated receptor-2 (PAR-2): Structure-function study of receptor activation by diverse peptides related to tethered-ligand epitopes
Authors: Maryanoff, BE Santulli, RJ McComsey, DF Hoekstra, WJ Hoey, K Smith, CE Addo, M Darrow, AL Andrade-Gordon, P
Citation: Be. Maryanoff et al., Protease-activated receptor-2 (PAR-2): Structure-function study of receptor activation by diverse peptides related to tethered-ligand epitopes, ARCH BIOCH, 386(2), 2001, pp. 195-204
3-aza-Cope rearrangement of quaternary N-allyl enammonium salts. Stereospecific 1,3 allyl migration from nitrogen to carbon on a tricyclic template
Authors: McComsey, DF Maryanoff, BE
Citation: Df. Mccomsey et Be. Maryanoff, 3-aza-Cope rearrangement of quaternary N-allyl enammonium salts. Stereospecific 1,3 allyl migration from nitrogen to carbon on a tricyclic template, J ORG CHEM, 65(16), 2000, pp. 4938-4943
Thrombin receptor-activating peptides (TRAPs): Investigation of bioactive conformations via structure-activity, spectroscopic, and computational studies
Authors: Ceruso, MA McComsey, DF Leo, GC Andrade-Gordon, P Addo, MF Scarborough, RM Oksenberg, D Maryanoff, BE
Citation: Ma. Ceruso et al., Thrombin receptor-activating peptides (TRAPs): Investigation of bioactive conformations via structure-activity, spectroscopic, and computational studies, BIO MED CH, 7(11), 1999, pp. 2353-2371
Macrocyclic hexapeptide analogues of the thrombin receptor (PAR-1) activation motif SFLLRN
Authors: McComsey, DF Hecker, LR Andrade-Gordon, P Addo, MF Maryanoff, BE
Citation: Df. Mccomsey et al., Macrocyclic hexapeptide analogues of the thrombin receptor (PAR-1) activation motif SFLLRN, BIOORG MED, 9(2), 1999, pp. 255-260
Potential anxiolytic agents. 3. Novel A-ring modified pyrido[1,2-a]benzimidazoles.
Authors: Maryanoff, BE Nortey, SO McNally, JJ Sanfilippo, PJ McComsey, DF Dubinsky, B Shank, RP Reitz, AB
Citation: Be. Maryanoff et al., Potential anxiolytic agents. 3. Novel A-ring modified pyrido[1,2-a]benzimidazoles., BIOORG MED, 9(11), 1999, pp. 1547-1552
Heterocycle-peptide hybrid compounds. Aminotriazole-containing agonists ofthe thrombin receptor (PAR-1)
Authors: McComsey, DF Hawkins, MJ Andrade-Gordon, P Addo, MF Oksenberg, D Maryanoff, BE
Citation: Df. Mccomsey et al., Heterocycle-peptide hybrid compounds. Aminotriazole-containing agonists ofthe thrombin receptor (PAR-1), BIOORG MED, 9(10), 1999, pp. 1423-1428
Macrocyclic hexapeptide analogues of the thrombin receptor (PAR-1) activation motif SFLLRN (vol 9, pg 255, 1999)
Authors: McComsey, DF Hecker, LR Andrade-Gordon, P Addo, MF Maryanoff, BE
Citation: Df. Mccomsey et al., Macrocyclic hexapeptide analogues of the thrombin receptor (PAR-1) activation motif SFLLRN (vol 9, pg 255, 1999), BIOORG MED, 9(10), 1999, pp. 1475-1475
Design, synthesis, and biological characterization of a peptide-mimetic antagonist for a tethered-ligand receptor
Authors: Andrade-Gordon, P Mayanoff, BE Derian, CK Zhang, HC Addo, MF Darrow, AL Eckardt, AJ Hoekstra, WJ McComsey, DF Oksenberg, D Reynolds, EE Santulli, RJ Scarborough, RM Smith, CE White, KB
Citation: P. Andrade-gordon et al., Design, synthesis, and biological characterization of a peptide-mimetic antagonist for a tethered-ligand receptor, P NAS US, 96(22), 1999, pp. 12257-12262
Potent, orally active GPIIb/IIIa antagonists containing a nipecotic acid subunit. Structure-activity studies leading to the discovery of RWJ-53308
Authors: Hoekstra, WJ Maryanoff, BE Damiano, BP Andrade-Gordon, P Cohen, JH Costanzo, MJ Haertlein, BJ Hecker, LR Hulshizer, BL Kauffman, JA Keane, P McComsey, DF Mitchell, JA Scott, L Shah, RD Yabut, SC
Citation: Wj. Hoekstra et al., Potent, orally active GPIIb/IIIa antagonists containing a nipecotic acid subunit. Structure-activity studies leading to the discovery of RWJ-53308, J MED CHEM, 42(25), 1999, pp. 5254-5265
Risultati: 1-12 |