Authors:
Farese, AM
Casey, DB
Vigneulle, RM
Siegel, NR
Finn, RF
Klover, JA
Smith, WG
McKearn, JP
MacVittie, TJ
Citation: Am. Farese et al., A single dose of pegylated leridistim significantly improves neutrophil recovery in sublethally irradiated rhesus macaques, STEM CELLS, 19(6), 2001, pp. 514-521
Authors:
Farese, AM
Casey, DB
Smith, WG
Vigneulle, RM
McKearn, JP
MacVittie, TJ
Citation: Am. Farese et al., Leridistim, a chimeric dual G-CSF and IL-3 receptor agonist, enhances multilineage hematopoietic recovery in a nonhuman primate model of radiation-induced myelosuppression: Effect of schedule, dose, and route of administration, STEM CELLS, 19(6), 2001, pp. 522-533
Authors:
Farese, AM
Smith, WG
Giri, JG
Siegel, N
McKearn, JP
MacVittie, TJ
Citation: Am. Farese et al., Promegapoietin-1a, an engineered chimeric IL-3 and Mpl-L receptor agonist,stimulates hematopoietic recovery in conventional and abbreviated schedules following radiation-induced myelosuppression in nonhuman primates, STEM CELLS, 19(4), 2001, pp. 329-338
Authors:
McCubrey, JA
Blalock, WL
Saleh, O
Pearce, M
Burrows, C
Steelman, LS
Lee, JT
Franklin, RA
Oberhaus, SM
Moye, PW
Doshi, PD
McKearn, JP
Citation: Ja. Mccubrey et al., Enhanced ability of daniplestim and myelopoietin-1 to suppress apoptosis in human hematopoietic cells, LEUKEMIA, 15(8), 2001, pp. 1203-1216
Authors:
Fleming, WH
Mulcahy, JM
McKearn, JP
Streeter, PR
Citation: Wh. Fleming et al., Progenipoietin-1: A multifunctional agonist of the granulocyte colony-stimulating factor receptor and fetal liver tyrosine kinase-3 is a potent mobilizer of hematopoietic stem cells, EXP HEMATOL, 29(8), 2001, pp. 943-951
Authors:
Doshi, PD
Giri, JG
Abegg, AL
Favara, JP
Huynh, MS
Kahn, LE
Minnerly, JC
Pegg, LE
Villani-Price, D
Siegel, NR
Staten, NR
Thomas, JW
McKearn, JP
Smith, WG
Citation: Pd. Doshi et al., Promegapoietin, a family of chimeric growth factors, supports megakaryocyte development through activation of IL-3 and c-Mpl ligand signaling pathways, EXP HEMATOL, 29(10), 2001, pp. 1177-1184
Authors:
Streeter, PR
Minster, NI
Kahn, LE
Hood, WF
Vickery, LE
Thurman, TL
Monahan, JB
Welply, JK
McKearn, JP
Woulfe, SL
Citation: Pr. Streeter et al., Progenipoietins: Biological characterization of a family of dual agonists of fetal liver tyrosine kinase-3 and the granulocyte colony-stimulating factor receptor, EXP HEMATOL, 29(1), 2001, pp. 41-50
Authors:
Hood, WF
Feng, YQG
Schilling, RJ
Gokarn, Y
Jarvis, C
Remsen, EE
Shieh, JJJ
Joy, W
Klein, BK
Polazzi, JO
Welply, JK
McKearn, JP
Monahan, JB
Citation: Wf. Hood et al., Modulation of the binding affinity of myelopoietins for the interleukin-3 receptor by the granulocyte colony-stimulating factor receptor agonist, BIOCHEM, 40(45), 2001, pp. 13598-13606
Authors:
Klein, BK
Shieh, JJ
Grabbe, E
Li, X
Welply, JK
McKearn, JP
Citation: Bk. Klein et al., Receptor binding kinetics of human IL-3 variants with altered proliferative activity, BIOC BIOP R, 288(5), 2001, pp. 1244-1249
Authors:
Scheding, S
Meister, B
Buhring, HJ
Baum, CM
McKearn, JP
Bock, T
Kanz, T
Brugger, W
Citation: S. Scheding et al., Effective ex vivo generation of granulopoietic postprogenitor cells from mobilized peripheral blood CD34(+) cells, EXP HEMATOL, 28(4), 2000, pp. 460-470
Authors:
MacVittie, TJ
Farese, AM
Smith, WG
Baum, CM
Burton, E
McKearn, JP
Citation: Tj. Macvittie et al., Myelopoietin, an engineered chimeric IL-3 and G-CSF receptor agonist, stimulates multilineage hematopoietic recovery in a nonhuman primate model of radiation-induced myelosuppression, BLOOD, 95(3), 2000, pp. 837-845
Authors:
Klein, BK
Olins, PO
Bauer, SC
Caparon, MH
Easton, AM
Braford, SR
Abrams, MA
Klover, JA
Paik, K
Thomas, JW
Hood, WF
Shieh, JJ
Polazzi, JO
Donnelly, AM
Zeng, DL
Welply, JK
McKearn, JP
Citation: Bk. Klein et al., Use of combinatorial mutagenesis to select for multiply substituted human interleukin-3 variants with improved pharmacologic properties, EXP HEMATOL, 27(12), 1999, pp. 1746-1756
Authors:
MacVittie, TJ
Farese, AM
Davis, TA
Lind, LB
McKearn, JP
Citation: Tj. Macvittie et al., Myelopoietin, a chimeric agonist of human interleukin 3 and granulocyte colony-stimulating factor receptors, mobilizes CD34(+) cells that rapidly engraft lethally x-irradiated nonhuman primates, EXP HEMATOL, 27(10), 1999, pp. 1557-1568
Authors:
McWherter, CA
Feng, YQ
Zurfluh, LL
Klein, BK
Baganoff, MP
Polazzi, JO
Hood, WF
Paik, K
Abegg, AL
Grabbe, ES
Shieh, JJ
Donnelly, AM
McKearn, JP
Citation: Ca. Mcwherter et al., Circular permutation of the granulocyte colony-stimulating factor receptoragonist domain of myelopoietin, BIOCHEM, 38(14), 1999, pp. 4564-4571