Authors:
Medhurst, AD
Zeng, BY
Charles, KJ
Gray, J
Reavill, C
Hunter, AJ
Shale, JA
Jenner, P
Citation: Ad. Medhurst et al., Up-regulation of secretoneurin immunoreactivity and secretogranin II mRNA in rat striatum following 6-hydroxydopamine lesioning and chronic L-dopa treatment, NEUROSCIENC, 105(2), 2001, pp. 353-364
Authors:
Medhurst, AD
Lezoualc'h, F
Fischmeister, R
Middlemiss, DN
Sanger, GJ
Citation: Ad. Medhurst et al., Quantitative mRNA analysis of five C-terminal splice variants of the human5-HT4 receptor in the central nervous system by TaqMan real time RT-PCR, MOL BRAIN R, 90(2), 2001, pp. 125-134
Authors:
Medhurst, AD
Rennie, G
Chapman, CG
Meadows, H
Duckworth, MD
Kelsell, RE
Gloger, II
Pangalos, MN
Citation: Ad. Medhurst et al., Distribution analysis of human two pore domain potassium channels in tissues of the central nervous system and periphery, MOL BRAIN R, 86(1-2), 2001, pp. 101-114
Authors:
Green, PJ
Warre, R
Hayes, PD
McNaughton, NCL
Medhurst, AD
Pangalos, M
Duckworth, DM
Randall, AD
Citation: Pj. Green et al., Kinetic modification of the alpha(1I) subunit-mediated T-type Ca2+ channelby a human neuronal Ca2+ channel gamma subunit, J PHYSL LON, 533(2), 2001, pp. 467-478
Authors:
Chambers, D
Medhurst, AD
Walsh, FS
Price, J
Mason, I
Citation: D. Chambers et al., Differential display of genes expressed at the midbrain-hindbrain junctionidentifies sprouty2: An FGF8-inducible member of a family of intracellularFGF antagonists, MOL CELL NE, 15(1), 2000, pp. 22-35
Authors:
Farmer, MK
Robbins, MJ
Medhurst, AD
Campbell, DA
Ellington, K
Duckworth, M
Brown, AM
Middlemiss, DN
Price, GW
Pangalos, MN
Citation: Mk. Farmer et al., Cloning and characterization of human NTT5 and v7-3: Two orphan transporters of the Na+/Cl--dependent neurotransmitter transporter gene family, GENOMICS, 70(2), 2000, pp. 241-252
Authors:
Robbins, MJ
Michalovich, D
Hill, J
Calver, AR
Medhurst, AD
Gloger, I
Sims, M
Middlemiss, DN
Pangalos, MN
Citation: Mj. Robbins et al., Molecular cloning and characterization of two novel retinoic acid-inducible orphan G-protein-coupled receptors (GPRC5B and GPRC5C), GENOMICS, 67(1), 2000, pp. 8-18
Authors:
Newton, RA
Bingham, S
Davey, PD
Medhurst, AD
Piercy, V
Raval, P
Parsons, AA
Sanger, GJ
Case, CP
Lawson, SN
Citation: Ra. Newton et al., Identification of differentially expressed genes in dorsal root ganglia following partial sciatic nerve injury, NEUROSCIENC, 95(4), 2000, pp. 1111-1120
Authors:
Calver, AR
Medhurst, AD
Robbins, MJ
Charles, KJ
Evans, ML
Harrison, DC
Stammers, M
Hughes, SA
Hervieu, G
Couve, A
Moss, SJ
Middlemiss, DN
Pangalos, MN
Citation: Ar. Calver et al., The expression of GABA(B1) and GABA(B2) receptor subunits in the CNS differs from that in peripheral tissues, NEUROSCIENC, 100(1), 2000, pp. 155-170
Authors:
Hayes, P
Meadows, HJ
Gunthorpe, MJ
Harries, MH
Duckworth, DM
Cairns, W
Harrison, DC
Clarke, CE
Ellington, K
Prinjha, RK
Barton, AJL
Medhurst, AD
Smith, GD
Topp, S
Murdock, P
Sanger, GJ
Terrett, J
Jenkins, O
Benham, CD
Randall, AD
Gloger, IS
Davis, JB
Citation: P. Hayes et al., Cloning and functional expression of a human orthologue of rat vanilloid receptor-1, PAIN, 88(2), 2000, pp. 205-215
Authors:
Harrison, DC
Medhurst, AD
Bond, BC
Campbell, CA
Davis, RP
Philpott, KL
Citation: Dc. Harrison et al., The use of quantitative RT-PCR to measure mRNA expression in a rat model of focal ischemia - caspase-3 as a case study, MOL BRAIN R, 75(1), 2000, pp. 143-149
Authors:
Medhurst, AD
Harrison, DC
Read, SJ
Campbell, CA
Robbins, MJ
Pangalos, MN
Citation: Ad. Medhurst et al., The use of TaqMan RT-PCR assays for semiquantitative analysis of gene expression in CNS tissues and disease models, J NEUROSC M, 98(1), 2000, pp. 9-20
Authors:
Meadows, HJ
Benham, CD
Cairns, W
Gloger, I
Jennings, C
Medhurst, AD
Murdock, P
Chapman, CG
Citation: Hj. Meadows et al., Cloning, localisation and functional expression of the human orthologue ofthe TREK-1 potassium channel, PFLUG ARCH, 439(6), 2000, pp. 714-722
Authors:
Sarau, HM
Griswold, DE
Bush, B
Potts, W
Sandhu, P
Lundberg, D
Foley, JJ
Schmidt, DB
Webb, EF
Martin, LD
Legos, JJ
Whitmore, RG
Barone, FC
Medhurst, AD
Luttmann, MA
Giardina, GAM
Hay, DWP
Citation: Hm. Sarau et al., Nonpeptide tachykinin receptor antagonists. II. Ppharmacological and pharmacokinetic profile of SB-222200, a central nervous system penetrant, potentand selective NK-3 receptor antagonist, J PHARM EXP, 295(1), 2000, pp. 373-381
Authors:
Reavill, C
Taylor, SG
Wood, MD
Ashmeade, T
Austin, NE
Avenell, KY
Boyfield, I
Branch, CL
Cilia, J
Coldwell, MC
Hadley, MS
Hunter, AJ
Jeffrey, P
Jewitt, F
Johnson, CN
Jones, DNC
Medhurst, AD
Middlemiss, DN
Nash, DJ
Riley, GJ
Routledge, C
Stemp, G
Thewlis, KM
Trail, B
Vong, AKK
Hagan, JJ
Citation: C. Reavill et al., Pharmacological actions of a novel, high-affinity, and selective human dopamine D-3 receptor antagonist, SB-277011-A, J PHARM EXP, 294(3), 2000, pp. 1154-1165
Authors:
Hagan, JJ
Price, GW
Jeffrey, P
Deeks, NJ
Stean, T
Piper, D
Smith, MI
Upton, N
Medhurst, AD
Middlemiss, DN
Riley, GJ
Lovell, PJ
Bromidge, SM
Thomas, DR
Citation: Jj. Hagan et al., Characterization of SB-269970-A, a selective 5-HT7 receptor antagonist, BR J PHARM, 130(3), 2000, pp. 539-548
Authors:
Giardina, GAM
Raveglia, LF
Grugni, M
Sarau, HM
Farina, C
Medhurst, AD
Graziani, D
Schmidt, DB
Rigolio, R
Luttmann, M
Cavagnera, S
Foley, JJ
Vecchietti, V
Hay, DWP
Citation: Gam. Giardina et al., Discovery of a novel class of selective non-peptide antagonists for the human neurokinin-3 receptor. 2. Identification of (S)-N-(1-phenylpropyl)-3-hydroxy-2-phenylquinoline-4-carboxamide (SB 223412), J MED CHEM, 42(6), 1999, pp. 1053-1065
Authors:
Medhurst, AD
Hirst, WD
Jerman, JC
Meakin, J
Roberts, JC
Testa, T
Smart, D
Citation: Ad. Medhurst et al., Molecular and pharmacological characterization of a functional tachykinin NK3 receptor cloned from the rabbit iris sphincter muscle, BR J PHARM, 128(3), 1999, pp. 627-636