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Results: 1-25 | 26-50 | 51-57
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Strategies for improved antigen delivery into dendritic cells
Authors: Rea, D Johnson, ME Havenga, MJE Melief, CJM Offringa, R
Citation: D. Rea et al., Strategies for improved antigen delivery into dendritic cells, TRENDS MO M, 7(3), 2001, pp. 91-94
Antigen loading of MHC class I molecules in the endocytic tract
Authors: Kleijmeer, MJ Escola, JN UytdeHaag, FGCM Jakobson, E Griffith, JM Osterhaus, ADME Stoorvogel, W Melief, CJM Rabouille, C Geuze, HJ
Citation: Mj. Kleijmeer et al., Antigen loading of MHC class I molecules in the endocytic tract, TRAFFIC, 2(2), 2001, pp. 124-137
Human T-cell responses to HLA-A-restricted high binding affinity peptides of human papillomavirus type 18 proteins E6 and E7
Authors: Rudolf, MP Man, S Melief, CJM Sette, A Kast, WM
Citation: Mp. Rudolf et al., Human T-cell responses to HLA-A-restricted high binding affinity peptides of human papillomavirus type 18 proteins E6 and E7, CLIN CANC R, 7(3), 2001, pp. 788S-795S
T-cell immunity against tumors, a delicate balancing act involving dendritic cells
Authors: Melief, CJM
Citation: Cjm. Melief, T-cell immunity against tumors, a delicate balancing act involving dendritic cells, PATH BIOL, 49(6), 2001, pp. 498-499
T cell infiltration and MHC I and II expression in the presence of tumor antigens: An immunohistochemical study in patients with serous epithelial ovarian cancer
Authors: Nijman, HW van Diest, PJ Poort-Keesom, RJJ von Mensdorff-Pouilly, S Verstraeten, RA Kummer, A Meijer, CJLM Melief, CJM Hilgers, J Kenemans, P
Citation: Hw. Nijman et al., T cell infiltration and MHC I and II expression in the presence of tumor antigens: An immunohistochemical study in patients with serous epithelial ovarian cancer, EUR J OB GY, 94(1), 2001, pp. 114-120
Pre-clinical safety and efficacy of TA-CIN, a recombinant HPV16 L2E6E7 fusion protein vaccine, in homologous and heterologous prime-boost regimens
Authors: van der Burg, SH Kwappenberg, KMC O'Neill, T Brandt, RMP Melief, CJM Hickling, JK Offringa, R
Citation: Sh. Van Der Burg et al., Pre-clinical safety and efficacy of TA-CIN, a recombinant HPV16 L2E6E7 fusion protein vaccine, in homologous and heterologous prime-boost regimens, VACCINE, 19(27), 2001, pp. 3652-3660
Blockade of the granzyme B/perforin pathway through overexpression of the serine protease inhibitor PI-9/SPI-6 constitutes a mechanism for immune escape by tumors
Authors: Medema, JP de Jong, J Peltenburg, LTC Verdegaal, EME Gorter, A Bres, SA Franken, KLMC Hahne, M Albar, JP Melief, CJM Offringa, R
Citation: Jp. Medema et al., Blockade of the granzyme B/perforin pathway through overexpression of the serine protease inhibitor PI-9/SPI-6 constitutes a mechanism for immune escape by tumors, P NAS US, 98(20), 2001, pp. 11515-11520
Longevity of antigen presentation and activation status of APC are decisive factors in the balance between CTL immunity versus tolerance
Authors: den Boer, AT Diehl, L van Mierlo, GJD van der Voort, EIH Fransen, MF Krimpenfort, P Melief, CJM Offringa, R Toes, REM
Citation: At. Den Boer et al., Longevity of antigen presentation and activation status of APC are decisive factors in the balance between CTL immunity versus tolerance, J IMMUNOL, 167(5), 2001, pp. 2522-2528
Rejection of intraocular tumors by CD4(+) T cells without induction of phthisis
Authors: Schurmans, LRHM Diehl, L den Boer, AT Sutmuller, RPM Boonman, ZFHM Medema, JP van der Voort, EIH Laman, J Melief, CJM Jager, MJ Toes, REM
Citation: Lrhm. Schurmans et al., Rejection of intraocular tumors by CD4(+) T cells without induction of phthisis, J IMMUNOL, 167(10), 2001, pp. 5832-5837
Highly efficient transduction of human monocyte-derived dendritic cells with subgroup B fiber-modified adenovirus vectors enhances transgene-encoded antigen presentation to cytotoxic T cells
Authors: Rea, D Havenga, MJE van den Assem, M Sutmuller, RPM Lemckert, A Hoeben, RC Bout, A Melief, CJM Offringa, R
Citation: D. Rea et al., Highly efficient transduction of human monocyte-derived dendritic cells with subgroup B fiber-modified adenovirus vectors enhances transgene-encoded antigen presentation to cytotoxic T cells, J IMMUNOL, 166(8), 2001, pp. 5236-5244
Rapid peptide turnover and inefficient presentation of exogenous antigen critically limit the activation of self-reactive CTL by dendritic cells
Authors: Ludewig, B McCoy, K Pericin, M Ochsenbein, AF Dumrese, T Odermatt, B Toes, REM Melief, CJM Hengartner, H Zinkernagel, RM
Citation: B. Ludewig et al., Rapid peptide turnover and inefficient presentation of exogenous antigen critically limit the activation of self-reactive CTL by dendritic cells, J IMMUNOL, 166(6), 2001, pp. 3678-3687
A measles virus glycoprotein-derived human CTL epitope is abundantly presented via the proteasomal-dependent MHC class I processing pathway
Authors: Herberts, CA Stittelaar, KJ van der Heeft, E van Ganns-van den Brink, J Poelen, MCM Roholl, PJM van Alphen, LJW Melief, CJM de Jong, APJM van Els, CACM
Citation: Ca. Herberts et al., A measles virus glycoprotein-derived human CTL epitope is abundantly presented via the proteasomal-dependent MHC class I processing pathway, J GEN VIROL, 82, 2001, pp. 2131-2142
Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses
Authors: Sutmuller, RPM van Dulvenvoorde, LM van Elsas, A Schumacher, TNM Wildenberg, ME Allison, JP Toes, REM Offringa, R Melief, CJM
Citation: Rpm. Sutmuller et al., Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses, J EXP MED, 194(6), 2001, pp. 823-832
Expression of the serpin serine protease inhibitor 6 protects dendritic cells from cytotoxic T lymphocyte-induced apoptosis: Differential modulation by T helper type 1 and type 2 cells
Authors: Medema, JP Schuurhuis, DH Rea, D van Tongeren, J de Jong, J Bres, SA Laban, S Toes, REM Toebes, M Schumacher, TNM Bladergroen, BA Ossendorp, F Kummer, JA Melief, CJM Offringa, R
Citation: Jp. Medema et al., Expression of the serpin serine protease inhibitor 6 protects dendritic cells from cytotoxic T lymphocyte-induced apoptosis: Differential modulation by T helper type 1 and type 2 cells, J EXP MED, 194(5), 2001, pp. 657-667
Elucidating the autoimmune and antitumor effector mechanisms of a treatment based on cytotoxic T lymphocyte antigen-4 blockade in combination with a B16 melanoma vaccine: Comparison of prophylaxis and therapy
Authors: van Elsas, A Sutmuller, RPM Hurwitz, AA Ziskin, J Villasenor, J Medema, JP Overwijk, W Restifo, NP Melief, CJM Offringa, R Allison, JP
Citation: A. Van Elsas et al., Elucidating the autoimmune and antitumor effector mechanisms of a treatment based on cytotoxic T lymphocyte antigen-4 blockade in combination with a B16 melanoma vaccine: Comparison of prophylaxis and therapy, J EXP MED, 194(4), 2001, pp. 481-489
Efficient identification of novel HLA-A0201-presented cytotoxic T lymphocyte epitopes in the widely expressed tumor antigen PRAME by proteasome-mediated digestion analysis
Authors: Kessler, JH Beekman, NJ Bres-Vloemans, SA Verdijk, P van Veelen, PA Kloosterman-Joosten, AM Vissers, DCJ ten Bosch, GJA Kester, MGD Sijts, A Drijfhout, JW Ossendorp, F Offringa, R Melief, CJM
Citation: Jh. Kessler et al., Efficient identification of novel HLA-A0201-presented cytotoxic T lymphocyte epitopes in the widely expressed tumor antigen PRAME by proteasome-mediated digestion analysis, J EXP MED, 193(1), 2001, pp. 73-88
Reorganization of multivesicular bodies regulates MHC class II antigen presentation by dendritic cells
Authors: Kleijmeer, M Ramm, G Schuurhuis, D Griffith, J Rescigno, M Ricciardi-Castagnoli, P Rudensky, AY Ossendorp, F Melief, CJM Stoorvogel, W Geuze, HJ
Citation: M. Kleijmeer et al., Reorganization of multivesicular bodies regulates MHC class II antigen presentation by dendritic cells, J CELL BIOL, 155(1), 2001, pp. 53-63
Natural T-HELPER immunity against human papillomavirus type 16 (HPV16) E7-derived peptide epitopes in patients with HPV16-positive cervical lesions: Identification of 3 human leukocyte antigen class II-restricted epitopes
Authors: van der Burg, SH Ressing, ME Kwappenberg, KMC de Jong, A Straathof, K de Jong, J Geluk, A van Meugaarden, KE Franken, KLMC Ottenhoff, THM Fleuren, GJ Kenter, G Melief, CJM Offringa, R
Citation: Sh. Van Der Burg et al., Natural T-HELPER immunity against human papillomavirus type 16 (HPV16) E7-derived peptide epitopes in patients with HPV16-positive cervical lesions: Identification of 3 human leukocyte antigen class II-restricted epitopes, INT J CANC, 91(5), 2001, pp. 612-618
Identification of three non-VNTR MUC1-derived HLA-A0201-restricted T-cellepitopes that induce protective anti-tumor immunity in HLA-A2/K-b-transgenic mice
Authors: Heukamp, LC van der Burg, SH Drijfhout, JW Melief, CJM Taylor-Papadimitriou, J Offringa, R
Citation: Lc. Heukamp et al., Identification of three non-VNTR MUC1-derived HLA-A0201-restricted T-cellepitopes that induce protective anti-tumor immunity in HLA-A2/K-b-transgenic mice, INT J CANC, 91(3), 2001, pp. 385-392
Long lasting p53-specific T cell memory responses in the absence of anti-p53 antibodies in patients with resected primary colorectal cancer
Authors: van der Burg, SH de Cock, K Menon, AG Franken, KLMC Palmen, M Redeker, A Drijfhout, JW Kuppen, PJK van de Velde, CJH Erdile, L Tollenaar, RAEM Melief, CJM Offringa, R
Citation: Sh. Van Der Burg et al., Long lasting p53-specific T cell memory responses in the absence of anti-p53 antibodies in patients with resected primary colorectal cancer, EUR J IMMUN, 31(1), 2001, pp. 146-155
Detection of T helper responses, but not of human papillomavirus-specific cytotoxic T lymphocyte responses, after peptide vaccination of patients with cervical carcinoma
Authors: Ressing, ME van Driel, WJ Brandt, RMP Kenter, GG de Jong, JH Bauknecht, T Fleuren, GJ Hoogerhout, P Offringa, R Sette, A Celis, E Grey, H Trimbos, BJ Kast, WM Melief, CJM
Citation: Me. Ressing et al., Detection of T helper responses, but not of human papillomavirus-specific cytotoxic T lymphocyte responses, after peptide vaccination of patients with cervical carcinoma, J IMMUNOTH, 23(2), 2000, pp. 255-266
BCR-ABL directed immunotherapy: A virtual reality?
Authors: Leeksma, OC Kessler, JH Huijbers, IJG Ten Bosch, GJA Melief, CJM
Citation: Oc. Leeksma et al., BCR-ABL directed immunotherapy: A virtual reality?, LEUK LYMPH, 38(1-2), 2000, pp. 175-181
Design and evaluation of antigen-specific vaccination strategies against cancer
Authors: Offringa, R van der Burg, SH Ossendorp, F Toes, REM Melief, CJM
Citation: R. Offringa et al., Design and evaluation of antigen-specific vaccination strategies against cancer, CURR OP IM, 12(5), 2000, pp. 576-582
The role of CD40 in peripheral T cell tolerance and immunity
Authors: Diehl, L Den Boer, AT van der Voort, EIH Melief, CJM Offringa, R Toes, REM
Citation: L. Diehl et al., The role of CD40 in peripheral T cell tolerance and immunity, J MOL MED-J, 78(7), 2000, pp. 363-371
Importance of CD4(+) T helper cell responses in tumor immunity
Authors: Ossendorp, F Toes, REM Offringa, R van der Burg, SH Melief, CJM
Citation: F. Ossendorp et al., Importance of CD4(+) T helper cell responses in tumor immunity, IMMUNOL LET, 74(1), 2000, pp. 75-79
Risultati: 1-25 | 26-50 | 51-57