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Results: 1-9 |
Results: 9
A cholesterol-lowering drug reduces beta-amyloid pathology in a transgenicmouse model of Alzheimer's disease
Authors: Refolo, LM Pappolla, MA LaFrancois, J Malester, B Schmidt, SD Thomas-Bryant, T Tint, GS Wang, R Mercken, M Petanceska, SS Duff, KE
Citation: Lm. Refolo et al., A cholesterol-lowering drug reduces beta-amyloid pathology in a transgenicmouse model of Alzheimer's disease, NEUROBIOL D, 8(5), 2001, pp. 890-899
The functional gamma-secretase inhibitor prevents production of amyloid beta 1-34 in human and murine cell lines
Authors: Vandermeeren, M Geraerts, M Pype, S Dillen, L Van Hove, C Mercken, M
Citation: M. Vandermeeren et al., The functional gamma-secretase inhibitor prevents production of amyloid beta 1-34 in human and murine cell lines, NEUROSCI L, 315(3), 2001, pp. 145-148
Nonfibrillar diffuse amyloid deposition due to a gamma(42)-secretase site mutation points to an essential role for N-truncated A beta(42) in Alzheimer's disease
Authors: Kumar-Singh, S De Jonghe, C Cruts, M Kleinert, R Wang, R Mercken, M De Strooper, B Vanderstichele, H Lofgren, A Vanderhoeven, I Backhovens, H Vanmechelen, E Kroisel, PM Van Broeckhoven, C
Citation: S. Kumar-singh et al., Nonfibrillar diffuse amyloid deposition due to a gamma(42)-secretase site mutation points to an essential role for N-truncated A beta(42) in Alzheimer's disease, HUM MOL GEN, 9(18), 2000, pp. 2589-2598
A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease
Authors: Janus, C Pearson, J McLaurin, J Mathews, PM Jiang, Y Schmidt, SD Chishti, MA Horne, P Heslin, D French, J Mount, HTJ Nixon, RA Mercken, M Bergeron, C Fraser, PE St George-Hyslop, P Westaway, D
Citation: C. Janus et al., A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease, NATURE, 408(6815), 2000, pp. 979-982
Glycogen synthase kinase-3 beta phosphorylates protein tau and rescues theaxonopathy in the central nervous system of human four-repeat tau transgenic mice
Authors: Spittaels, K Van den Haute, C Van Dorpe, J Geerts, H Mercken, M Bruynseels, K Lasrado, R Vandezande, K Laenen, I Boon, T Van Lint, J Vandenheede, J Moechars, D Loos, R Van Leuven, F
Citation: K. Spittaels et al., Glycogen synthase kinase-3 beta phosphorylates protein tau and rescues theaxonopathy in the central nervous system of human four-repeat tau transgenic mice, J BIOL CHEM, 275(52), 2000, pp. 41340-41349
Prominent cerebral amyloid angiopathy in transgenic mice overexpressing the London mutant of human APP in neurons
Authors: Van Dorpe, J Smeijers, L Dewachter, I Nuyens, D Spittaels, K Van den Haute, C Mercken, M Moechars, D Laenen, I Kuiperi, C Bruynseels, K Tesseur, I Loos, R Vanderstichele, H Checler, F Sciot, R Van Leuven, F
Citation: J. Van Dorpe et al., Prominent cerebral amyloid angiopathy in transgenic mice overexpressing the London mutant of human APP in neurons, AM J PATH, 157(4), 2000, pp. 1283-1298
Impaired proteolytic processing of Presenilin-1 in chromosome 14-linked familial Alzheimer's disease patient lymphocytes
Authors: Takahashi, H Mercken, M Honda, T Saito, Y Murayama, M Song, SC Takashima, A
Citation: H. Takahashi et al., Impaired proteolytic processing of Presenilin-1 in chromosome 14-linked familial Alzheimer's disease patient lymphocytes, NEUROSCI L, 260(2), 1999, pp. 121-124
Dual roles of proteasome in the metabolism of presenilin 1
Authors: Honda, T Yasutake, K Nihonmatsu, N Mercken, M Takahashi, H Murayama, O Murayama, M Sato, K Omori, A Tsubuki, S Saido, TC Takashima, A
Citation: T. Honda et al., Dual roles of proteasome in the metabolism of presenilin 1, J NEUROCHEM, 72(1), 1999, pp. 255-261
Prominent axonopathy in the brain and spinal cord of transgenic mice overexpressing four-repeat human tau protein
Authors: Spittaels, K Van den Haute, C Van Dorpe, J Bruynseels, K Vandezande, K Laenen, I Geerts, H Mercken, M Sciot, R Van Lommel, A Loos, R Van Leuven, F
Citation: K. Spittaels et al., Prominent axonopathy in the brain and spinal cord of transgenic mice overexpressing four-repeat human tau protein, AM J PATH, 155(6), 1999, pp. 2153-2165
Risultati: 1-9 |