Authors:
Clifford, SC
Cockman, ME
Smallwood, AC
Mole, DR
Woodward, ER
Maxwell, PH
Ratcliffe, PJ
Maher, ER
Citation: Sc. Clifford et al., Contrasting effects on HIF-1 alpha regulation by disease-causing pVHL mutations correlate with patterns of tumourigenesis in von Hippel-Lindau disease, HUM MOL GEN, 10(10), 2001, pp. 1029-1038
Authors:
Epstein, ACR
Gleadle, JM
McNeill, LA
Hewitson, KS
O'Rourke, J
Mole, DR
Mukherji, M
Metzen, E
Wilson, MI
Dhanda, A
Tian, YM
Masson, N
Hamilton, DL
Jaakkola, P
Barstead, R
Hodgkin, J
Maxwell, PH
Pugh, CW
Schofield, CJ
Ratcliffe, PJ
Citation: Acr. Epstein et al., C-elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation, CELL, 107(1), 2001, pp. 43-54
Authors:
Jaakkola, P
Mole, DR
Tian, YM
Wilson, MI
Gielbert, J
Gaskell, SJ
von Kriegsheim, A
Hebestreit, HF
Mukherji, M
Schofield, CJ
Maxwell, PH
Pugh, CW
Ratcliffe, PJ
Citation: P. Jaakkola et al., Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O-2-regulated prolyl hydroxylation, SCIENCE, 292(5516), 2001, pp. 468-472
Authors:
Cockman, ME
Masson, N
Mole, DR
Jaakkola, P
Chang, GW
Clifford, SC
Maher, ER
Pugh, CW
Ratcliffe, PJ
Maxwell, PH
Citation: Me. Cockman et al., Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein, J BIOL CHEM, 275(33), 2000, pp. 25733-25741