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Results: 1-25 | 26-35
Results: 1-25/35
Phase I trial of ISIS 5132, an antisense oligonucleotide inhibitor of c-raf-1, administered by 24-hour weekly infusion to patients with advanced cancer
Authors: Rudin, CM Holmlund, J Fleming, GF Mani, S Stadler, WM Schumm, P Monia, BP Johnston, JF Geary, R Yu, RZ Kwoh, TJ Dorr, FA Ratain, MJ
Citation: Cm. Rudin et al., Phase I trial of ISIS 5132, an antisense oligonucleotide inhibitor of c-raf-1, administered by 24-hour weekly infusion to patients with advanced cancer, CLIN CANC R, 7(5), 2001, pp. 1214-1220
Discovery and analysis of antisense oligonucleotide activity in cell culture
Authors: Baker, BF Condon, TP Koller, E McKay, RA Siwkowski, AM Vickers, TA Monia, BP
Citation: Bf. Baker et al., Discovery and analysis of antisense oligonucleotide activity in cell culture, METHODS, 23(2), 2001, pp. 191-198
In vitro and in vivo inhibition of interleukin (IL)-5 - Mediated eosinopoiesis by murine IL-5R alpha antisense oligonucleotide
Authors: Lach-Trifilieff, E McKay, RA Monia, BP Karras, JG Walker, C
Citation: E. Lach-trifilieff et al., In vitro and in vivo inhibition of interleukin (IL)-5 - Mediated eosinopoiesis by murine IL-5R alpha antisense oligonucleotide, AM J RESP C, 24(2), 2001, pp. 116-122
Inhibition of telomerase by 2 '-O-(2-methoxyethyl) RNA oligomers: effect of length, phosphorothioate substitution and time inside cells
Authors: Elayadi, AN Demieville, A Wancewicz, EV Monia, BP Corey, DR
Citation: An. Elayadi et al., Inhibition of telomerase by 2 '-O-(2-methoxyethyl) RNA oligomers: effect of length, phosphorothioate substitution and time inside cells, NUCL ACID R, 29(8), 2001, pp. 1683-1689
Inhibition of c-Jun N-terminal kinase 1, but not c-Jun N-terminal kinase 2, suppresses apoptosis induced by ischemia/reoxygenation in rat cardiac myocytes
Authors: Hreniuk, D Garay, M Gaarde, W Monia, BP Mckay, RA Cioffi, CL
Citation: D. Hreniuk et al., Inhibition of c-Jun N-terminal kinase 1, but not c-Jun N-terminal kinase 2, suppresses apoptosis induced by ischemia/reoxygenation in rat cardiac myocytes, MOLEC PHARM, 59(4), 2001, pp. 867-874
Antitumor activity of antisense clusterin oligonucleotides is improved in vitro and in vivo by incorporation of 2 '-O-(2-methoxy)ethyl chemistry
Authors: Zellweger, T Miyake, H Cooper, S Chi, K Conklin, BS Monia, BP Gleave, ME
Citation: T. Zellweger et al., Antitumor activity of antisense clusterin oligonucleotides is improved in vitro and in vivo by incorporation of 2 '-O-(2-methoxy)ethyl chemistry, J PHARM EXP, 298(3), 2001, pp. 934-940
Relaxin positively regulates matrix metalloproteinase expression in human lower uterine segment fibroblasts using a tyrosine kinase signaling pathway
Authors: Palejwala, S Stein, DE Weiss, G Monia, BP Tortoriello, D Goldsmith, LT
Citation: S. Palejwala et al., Relaxin positively regulates matrix metalloproteinase expression in human lower uterine segment fibroblasts using a tyrosine kinase signaling pathway, ENDOCRINOL, 142(8), 2001, pp. 3405-3413
Inhibition of focal adhesion kinase expression or activity disrupts epidermal growth factor-stimulated signaling promoting the migration of invasive human carcinoma cells
Authors: Hauck, CR Sieg, DJ Hsia, DA Loftus, JC Gaarde, WA Monia, BP Schlaepfer, DD
Citation: Cr. Hauck et al., Inhibition of focal adhesion kinase expression or activity disrupts epidermal growth factor-stimulated signaling promoting the migration of invasive human carcinoma cells, CANCER RES, 61(19), 2001, pp. 7079-7090
In vivo suppression of Bcl-X-L expression facilitates chemotherapy-inducedleukaemia cell death in a SCID/NOD-Hu model
Authors: Fennell, DA Corbo, MV Dean, NM Monia, BP Cotter, FE
Citation: Da. Fennell et al., In vivo suppression of Bcl-X-L expression facilitates chemotherapy-inducedleukaemia cell death in a SCID/NOD-Hu model, BR J HAEM, 112(3), 2001, pp. 706-713
A role for antisense technology in the discovery of highly specific and versatile signal transduction inhibitors
Authors: Monia, BP Koller, E Gaarde, WA
Citation: Bp. Monia et al., A role for antisense technology in the discovery of highly specific and versatile signal transduction inhibitors, ANTISENSE DRUG TECHNOLOGY: PRINCIPLES, STRATEGIES, AND APPLICATIONS, 2001, pp. 83-105
Pharmacology of 2 '-O-(2-methoxy)ethyl-modified antisense oligonucleotides
Authors: Dean, NM Butler, M Monia, BP Manoharan, M
Citation: Nm. Dean et al., Pharmacology of 2 '-O-(2-methoxy)ethyl-modified antisense oligonucleotides, ANTISENSE DRUG TECHNOLOGY: PRINCIPLES, STRATEGIES, AND APPLICATIONS, 2001, pp. 319-338
Elucidating cell signaling mechanisms using antisense technology
Authors: Koller, E Gaarde, WA Monia, BP
Citation: E. Koller et al., Elucidating cell signaling mechanisms using antisense technology, TRENDS PHAR, 21(4), 2000, pp. 142-148
Antisense inhibition of membrane-bound human interleukin-5 receptor-alpha chain does not affect soluble receptor expression and induces apoptosis in TF-1 cells
Authors: Karras, JG McKay, RA Lu, T Dean, NM Monia, BP
Citation: Jg. Karras et al., Antisense inhibition of membrane-bound human interleukin-5 receptor-alpha chain does not affect soluble receptor expression and induces apoptosis in TF-1 cells, ANTISENSE N, 10(5), 2000, pp. 347-357
Role of Ras isoforms in the stimulated proliferation of human renal fibroblasts in primary culture
Authors: Sharpe, CC Dockrell, MEC Noor, MI Monia, BP Hendry, BM
Citation: Cc. Sharpe et al., Role of Ras isoforms in the stimulated proliferation of human renal fibroblasts in primary culture, J AM S NEPH, 11(9), 2000, pp. 1600-1606
Antisense approaches for the treatment of cancer
Authors: Monia, BP Holmlund, J Dorr, FA
Citation: Bp. Monia et al., Antisense approaches for the treatment of cancer, CANCER INV, 18(7), 2000, pp. 635-650
Evaluation of biological role of c-Jun N-terminal kinase using an antisense approach
Authors: Cioffi, CL Monia, BP
Citation: Cl. Cioffi et Bp. Monia, Evaluation of biological role of c-Jun N-terminal kinase using an antisense approach, METH ENZYM, 314, 2000, pp. 363-378
Inhibition of C-raf expression by antisense oligonucleotides extends heartallograft survival in rats
Authors: Stepkowski, SM Qu, XM Wang, ME Tian, L Chen, WH Wancewicz, EV Johnston, JF Bennett, CF Monia, BP
Citation: Sm. Stepkowski et al., Inhibition of C-raf expression by antisense oligonucleotides extends heartallograft survival in rats, TRANSPLANT, 70(4), 2000, pp. 656-661
Deletion of individual exons and induction of soluble murine interleukin-5receptor-alpha chain expression through antisense oligonucleotide-mediatedredirection of pre-mRNA splicing
Authors: Karras, JG McKay, RA Dean, NM Monia, BP
Citation: Jg. Karras et al., Deletion of individual exons and induction of soluble murine interleukin-5receptor-alpha chain expression through antisense oligonucleotide-mediatedredirection of pre-mRNA splicing, MOLEC PHARM, 58(2), 2000, pp. 380-387
Inhibition of antigen-induced eosinophilia and late phase airway hyperresponsiveness by an IL-5 antisense oligonucleotide in mouse models of asthma
Authors: Karras, JG McGraw, K McKay, RA Cooper, SR Lerner, D Lu, T Walker, C Dean, NM Monia, BP
Citation: Jg. Karras et al., Inhibition of antigen-induced eosinophilia and late phase airway hyperresponsiveness by an IL-5 antisense oligonucleotide in mouse models of asthma, J IMMUNOL, 164(10), 2000, pp. 5409-5415
Inhibition of progression to androgen-independence by combined adjuvant treatment with antisense bcl-xL and antisense Bcl-2 oligonucleotides plus taxol after castration in the Shionogi tumor model
Authors: Miyake, H Monia, BP Gleave, ME
Citation: H. Miyake et al., Inhibition of progression to androgen-independence by combined adjuvant treatment with antisense bcl-xL and antisense Bcl-2 oligonucleotides plus taxol after castration in the Shionogi tumor model, INT J CANC, 86(6), 2000, pp. 855-862
STAT3 regulates the growth and immunoglobulin production of BCL1 B cell lymphoma through control of cell cycle progression
Authors: Karras, JG McKay, RA Lu, T Pych, J Frank, DA Rothstein, TL Monia, BP
Citation: Jg. Karras et al., STAT3 regulates the growth and immunoglobulin production of BCL1 B cell lymphoma through control of cell cycle progression, CELL IMMUN, 202(2), 2000, pp. 124-135
Inhibition of hypoxia/reoxygenation-induced apoptosis by an antisense oligonucleotide targeted to JNK1 in human kidney cells
Authors: Garay, M Gaarde, W Monia, BP Nero, P Cioffi, CL
Citation: M. Garay et al., Inhibition of hypoxia/reoxygenation-induced apoptosis by an antisense oligonucleotide targeted to JNK1 in human kidney cells, BIOCH PHARM, 59(9), 2000, pp. 1033-1043
Inhibition of cell growth by antisense oligonucleotides targeting the growth-related protein kinase c-raf
Authors: Fabbro, D Monia, BP Altmann, KH Geiger, T
Citation: D. Fabbro et al., Inhibition of cell growth by antisense oligonucleotides targeting the growth-related protein kinase c-raf, METH MOL M, 35, 2000, pp. 167-188
Antisense raf oligodeoxyribonucleotide is a radiosensitizer in vivo
Authors: Gokhale, PC McRae, D Monia, BP Bagg, A Rahman, A Dritschilo, A Kasid, U
Citation: Pc. Gokhale et al., Antisense raf oligodeoxyribonucleotide is a radiosensitizer in vivo, ANTISENSE N, 9(2), 1999, pp. 191-201
Anti-tumor activity of C-raf antisense (vol 2, pg 668, 1996)
Authors: Monia, BP
Citation: Bp. Monia, Anti-tumor activity of C-raf antisense (vol 2, pg 668, 1996), NAT MED, 5(2), 1999, pp. 127-127
Risultati: 1-25 | 26-35