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Results: 1-7 |
Results: 7
HIGHLY REGIOSELECTIVE NITRATION REACTIONS PROVIDE A VERSATILE METHOD OF FUNCTIONALIZING BENZOCYCLOHEPTAPYRIDINE TRICYCLIC RING-SYSTEMS - APPLICATION TOWARD PREPARATION OF NANOMOLAR INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE
Authors: NJOROGE FG VIBULBHAN B PINTO P CHAN TM OSTERMAN R REMISZEWSKI S DELROSARIO J DOLL R GIRIJAVALLABHAN V GANGULY AK
Citation: Fg. Njoroge et al., HIGHLY REGIOSELECTIVE NITRATION REACTIONS PROVIDE A VERSATILE METHOD OF FUNCTIONALIZING BENZOCYCLOHEPTAPYRIDINE TRICYCLIC RING-SYSTEMS - APPLICATION TOWARD PREPARATION OF NANOMOLAR INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE, Journal of organic chemistry, 63(3), 1998, pp. 445-451
-PIPERIDINYL]-2-OXO-ETHYL]-1-PIPERIDINECARBOXAMIDE (SCH-66336) - A VERY POTENT FARNESYL-PROTEIN TRANSFERASE INHIBITOR AS A NOVEL ANTITUMOR AGENT())
Authors: NJOROGE FG TAVERAS AG KELLY J REMISZEWSKI S MALLAMS AK WOLIN R AFONSO A COOPER AB RANE DF LIU YT WONG J VIBULBHAN B PINTO P DESKUS J ALVAREZ CS DELROSARIO J CONNOLLY M WANG J DESAI J ROSSMAN RR BISHOP WR PATTON R WANG L KIRSCHMEIER P BRYANT MS NOMEIR AA LIN CC LIU M MCPHAIL AT DOLL RJ GIRIJAVALLABHAN VM GANGULY AK
Citation: Fg. Njoroge et al., -PIPERIDINYL]-2-OXO-ETHYL]-1-PIPERIDINECARBOXAMIDE (SCH-66336) - A VERY POTENT FARNESYL-PROTEIN TRANSFERASE INHIBITOR AS A NOVEL ANTITUMOR AGENT()), Journal of medicinal chemistry, 41(24), 1998, pp. 4890-4902
POTENT, SELECTIVE, AND ORALLY BIOAVAILABLE TRICYCLIC PYRIDYL ACETAMIDE N-OXIDE INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE WITH ENHANCED IN-VIVO ANTITUMOR-ACTIVITY
Authors: NJOROGE FG VIBULBHAN B PINTO P BISHOP WR BRYANT MS NOMEIR AA LIN CC LIU M DOLL RJ GIRIJAVALLABHAN V GANGULY AK
Citation: Fg. Njoroge et al., POTENT, SELECTIVE, AND ORALLY BIOAVAILABLE TRICYCLIC PYRIDYL ACETAMIDE N-OXIDE INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE WITH ENHANCED IN-VIVO ANTITUMOR-ACTIVITY, Journal of medicinal chemistry, 41(10), 1998, pp. 1561-1567
ANTITUMOR-ACTIVITY OF SCH-66336, AN ORALLY BIOAVAILABLE TRICYCLIC INHIBITOR OF FARNESYL-PROTEIN TRANSFERASE, IN HUMAN TUMOR XENOGRAFT MODELS AND WAP-RAS TRANSGENIC MICE
Authors: LIU M BRYANT MS CHEN JP LEE SN YAREMKO B LIPARI P MALKOWSKI M FERRARI E NIELSEN L PRIOLI N DELL J SINHA D SYED J KORFMACHER WA NOMEIR AA LIN CC WANG L TAVERAS AG DOLL RJ NJOROGE FG MALLAMS AK REMISZEWSKI S CATINO JJ GIRIJAVALLABHAN VM KIRSCHMEIER P BISHOP WR
Citation: M. Liu et al., ANTITUMOR-ACTIVITY OF SCH-66336, AN ORALLY BIOAVAILABLE TRICYCLIC INHIBITOR OF FARNESYL-PROTEIN TRANSFERASE, IN HUMAN TUMOR XENOGRAFT MODELS AND WAP-RAS TRANSGENIC MICE, Cancer research, 58(21), 1998, pp. 4947-4956
STRUCTURE-ACTIVITY RELATIONSHIP OF 3-SUBSTITUTED ,6]CYCLOHEPTA[1,2-B]PYRIDIN-11-YLIDENE)-PIPERIDINE INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE - DESIGN AND SYNTHESIS OF IN-VIVO ACTIVE ANTITUMOR COMPOUNDS
Authors: NJOROGE FG VIBULBHAN B RANE DF BISHOP WR PETRIN J PATTON R BRYANT MS CHEN KJ NOMEIR AA LIN CC LIU M KING I CHEN JP LEE SN YAREMKO B DELL J LIPARI P MALKOWSKI M LI ZJ CATINO J DOLL RJ GIRIJAVALLABHAN V GANGULY AK
Citation: Fg. Njoroge et al., STRUCTURE-ACTIVITY RELATIONSHIP OF 3-SUBSTITUTED ,6]CYCLOHEPTA[1,2-B]PYRIDIN-11-YLIDENE)-PIPERIDINE INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE - DESIGN AND SYNTHESIS OF IN-VIVO ACTIVE ANTITUMOR COMPOUNDS, Journal of medicinal chemistry, 40(26), 1997, pp. 4290-4301
NOVEL TRICYCLIC AMINOACETYL AND SULFONAMIDE INHIBITORS OF RAS FARNESYL-PROTEIN TRANSFERASE
Authors: NJOROGE FG VIBULBHAN B ALVAREZ CS BISHOP WR PETRIN J DOLL RJ GIRIJAVALLABHAN V GANGULY AK
Citation: Fg. Njoroge et al., NOVEL TRICYCLIC AMINOACETYL AND SULFONAMIDE INHIBITORS OF RAS FARNESYL-PROTEIN TRANSFERASE, Bioorganic & medicinal chemistry letters, 6(24), 1996, pp. 2977-2982
STRUCTURAL INTERACTION OF NATURAL AND SYNTHETIC INHIBITORS WITH THE VENOM METALLOPROTEINASE, ATROLYSIN-C (FORM-D)
Authors: ZHANG DC BOTOS I GOMISRUTH FX DOLL R BLOOD C NJOROGE FG FOX JW BODE W MEYER EF
Citation: Dc. Zhang et al., STRUCTURAL INTERACTION OF NATURAL AND SYNTHETIC INHIBITORS WITH THE VENOM METALLOPROTEINASE, ATROLYSIN-C (FORM-D), Proceedings of the National Academy of Sciences of the United Statesof America, 91(18), 1994, pp. 8447-8451
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