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Results: 1-25 | 26-26
Results: 1-25/26
PRECLINICAL PHARMACOKINETICS OF PACLITAXEL AND DOCETAXEL
Authors: SPARREBOOM A VANTELLINGEN O NOOIJEN WJ BEIJNEN JH
Citation: A. Sparreboom et al., PRECLINICAL PHARMACOKINETICS OF PACLITAXEL AND DOCETAXEL, Anti-cancer drugs, 9(1), 1998, pp. 1-17
IN-VITRO AND IN-VIVO BONE-MARROW TOXICITY ASSAYS IN THE CLINICAL DEVELOPMENT OF NEW DRUGS - CARZELESIN AS AN EXAMPLE
Authors: VANTELLINGEN O SCHAAF LJ PUNT CJA AWADA A VANDERVALK M HENRAR REC WAGENER DJT PICCART MJ NOOIJEN WJ BEIJNEN JH
Citation: O. Vantellingen et al., IN-VITRO AND IN-VIVO BONE-MARROW TOXICITY ASSAYS IN THE CLINICAL DEVELOPMENT OF NEW DRUGS - CARZELESIN AS AN EXAMPLE, Annals of oncology, 9, 1998, pp. 204-204
A CLINICAL PHARMACOKINETICS STUDY OF CARZELESIN GIVEN BY SHORT-TERM INTRAVENOUS-INFUSION IN A PHASE-I STUDY
Authors: VANTELLINGEN O PUNT CJA AWADA A WAGENER DJT PICCART MJ GROOT Y SCHAAF LJ HENRAR REC NOOIJEN WJ BEIJNEN JH
Citation: O. Vantellingen et al., A CLINICAL PHARMACOKINETICS STUDY OF CARZELESIN GIVEN BY SHORT-TERM INTRAVENOUS-INFUSION IN A PHASE-I STUDY, Cancer chemotherapy and pharmacology, 41(5), 1998, pp. 377-384
RANDOMIZED TRIAL OF HIGH-DOSE CHEMOTHERAPY AND HEMATOPOIETIC PROGENITOR-CELL SUPPORT IN OPERABLE BREAST-CANCER WITH EXTENSIVE AXILLARY LYMPH-NODE INVOLVEMENT
Authors: RODENHUIS S RICHEL DJ VANDERWALL E SCHORNAGEL JH BAARS JW KONING CCE PETERSE JL BORGER JH NOOIJEN WJ BAKX R DALESIO O RUTGERS E
Citation: S. Rodenhuis et al., RANDOMIZED TRIAL OF HIGH-DOSE CHEMOTHERAPY AND HEMATOPOIETIC PROGENITOR-CELL SUPPORT IN OPERABLE BREAST-CANCER WITH EXTENSIVE AXILLARY LYMPH-NODE INVOLVEMENT, Lancet, 352(9127), 1998, pp. 515-521
COMPARATIVE PHARMACOLOGY OF THE NOVEL CYCLOPROPYLPYRROLOINDOLE-PRODRUG CARZELESIN IN MICE, RATS, AND HUMANS
Authors: VANTELLINGEN O NOOIJEN WJ SCHAAF LJ VANDERVALK M VANASPEREN J HENRAR REC BEIJNEN JH
Citation: O. Vantellingen et al., COMPARATIVE PHARMACOLOGY OF THE NOVEL CYCLOPROPYLPYRROLOINDOLE-PRODRUG CARZELESIN IN MICE, RATS, AND HUMANS, Cancer research, 58(11), 1998, pp. 2410-2416
THE VASCULAR COMPARTMENT HAMPERS ACCURATE DETERMINATION OF TENIPOSIDEPENETRATION INTO BRAIN-TUMOR TISSUE
Authors: VANTELLINGEN O BOOGERD W NOOIJEN WJ BEIJNEN JH
Citation: O. Vantellingen et al., THE VASCULAR COMPARTMENT HAMPERS ACCURATE DETERMINATION OF TENIPOSIDEPENETRATION INTO BRAIN-TUMOR TISSUE, Cancer chemotherapy and pharmacology, 40(4), 1997, pp. 330-334
LIMITED ORAL BIOAVAILABILITY AND ACTIVE EPITHELIAL EXCRETION OF PACLITAXEL (TAXOL) CAUSED BY P-GLYCOPROTEIN IN THE INTESTINE
Authors: SPARREBOOM A VANASPEREN J MAYER U SCHINKEL AH SMIT JW MEIJER DKF BORST P NOOIJEN WJ BEIJNEN JH VANTELLINGEN O
Citation: A. Sparreboom et al., LIMITED ORAL BIOAVAILABILITY AND ACTIVE EPITHELIAL EXCRETION OF PACLITAXEL (TAXOL) CAUSED BY P-GLYCOPROTEIN IN THE INTESTINE, Proceedings of the National Academy of Sciences of the United Statesof America, 94(5), 1997, pp. 2031-2035
ENHANCED ORAL BIOAVAILABILITY OF PACLITAXEL IN MICE TREATED WITH THE P-GLYCOPROTEIN BLOCKER SDZ-PSC-833
Authors: VANASPEREN J VANTELLINGEN O SPARREBOOM A SCHINKEL AH BORST P NOOIJEN WJ BEIJNEN JH
Citation: J. Vanasperen et al., ENHANCED ORAL BIOAVAILABILITY OF PACLITAXEL IN MICE TREATED WITH THE P-GLYCOPROTEIN BLOCKER SDZ-PSC-833, British Journal of Cancer, 76(9), 1997, pp. 1181-1183
ALTERED PHARMACOKINETICS OF VINBLASTINE IN MDR1A P-GLYCOPROTEIN-DEFICIENT MICE
Authors: VANASPEREN J SCHINKEL AH BEIJNEN JH NOOIJEN WJ BORST P VANTELLINGEN O
Citation: J. Vanasperen et al., ALTERED PHARMACOKINETICS OF VINBLASTINE IN MDR1A P-GLYCOPROTEIN-DEFICIENT MICE, Journal of the National Cancer Institute, 88(14), 1996, pp. 994-999
DETERMINATION OF POLYOXYETHYLENEGLYCEROL TRIRICINOLEATE-35 (CREMOPHOREL) IN PLASMA BY PRECOLUMN DERIVATIZATION AND REVERSED-PHASE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY
Authors: SPARREBOOM A VANTELLINGEN O HUIZING MT NOOIJEN WJ BEIJNEN JH
Citation: A. Sparreboom et al., DETERMINATION OF POLYOXYETHYLENEGLYCEROL TRIRICINOLEATE-35 (CREMOPHOREL) IN PLASMA BY PRECOLUMN DERIVATIZATION AND REVERSED-PHASE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY, Journal of chromatography B. Biomedical applications, 681(2), 1996, pp. 355-362
TISSUE DISTRIBUTION, METABOLISM AND EXCRETION OF PACLITAXEL IN MICE
Authors: SPARREBOOM A VANTELLINGEN O NOOIJEN WJ BEIJNEN JH
Citation: A. Sparreboom et al., TISSUE DISTRIBUTION, METABOLISM AND EXCRETION OF PACLITAXEL IN MICE, Anti-cancer drugs, 7(1), 1996, pp. 78-86
FEASIBILITY OF MULTIPLE COURSES OF HIGH-DOSE CYCLOPHOSPHAMIDE, THIOTEPA, AND CARBOPLATIN FOR BREAST-CANCER OR GERM-CELL CANCER
Authors: RODENHUIS S WESTERMANN A HOLTKAMP MJ NOOIJEN WJ BAARS JW VANDERWALL E SLAPERCORTENBACH ICM SCHORNAGEL JH
Citation: S. Rodenhuis et al., FEASIBILITY OF MULTIPLE COURSES OF HIGH-DOSE CYCLOPHOSPHAMIDE, THIOTEPA, AND CARBOPLATIN FOR BREAST-CANCER OR GERM-CELL CANCER, Journal of clinical oncology, 14(5), 1996, pp. 1473-1483
UNCHANGED PHARMACOKINETICS OF ETOPOSIDE GIVEN BY INTRAARTERIAL HEPATIC INFUSION AS COMPARED WITH IV INFUSION
Authors: VANTELLINGEN O KUCK MT VLASVELD LT RODENHUIS S NOOIJEN WJ BEIJNEN JH
Citation: O. Vantellingen et al., UNCHANGED PHARMACOKINETICS OF ETOPOSIDE GIVEN BY INTRAARTERIAL HEPATIC INFUSION AS COMPARED WITH IV INFUSION, Cancer chemotherapy and pharmacology, 38(4), 1996, pp. 387-390
ISOLATION, PURIFICATION AND BIOLOGICAL-ACTIVITY OF MAJOR DOCETAXEL METABOLITES FROM HUMAN FECES
Authors: SPARREBOOM A VANTELLINGEN O SCHERRENBURG EJ BOESEN JJB HUIZING MT NOOIJEN WJ VERSLUIS C BEIJNEN JH
Citation: A. Sparreboom et al., ISOLATION, PURIFICATION AND BIOLOGICAL-ACTIVITY OF MAJOR DOCETAXEL METABOLITES FROM HUMAN FECES, Drug metabolism and disposition, 24(6), 1996, pp. 655-658
NONLINEAR PHARMACOKINETICS OF PACLITAXEL IN MICE RESULTS FROM THE PHARMACEUTICAL VEHICLE CREMOPHOR EL
Authors: SPARREBOOM A VANTELLINGEN O NOOIJEN WJ BEIJNEN JH
Citation: A. Sparreboom et al., NONLINEAR PHARMACOKINETICS OF PACLITAXEL IN MICE RESULTS FROM THE PHARMACEUTICAL VEHICLE CREMOPHOR EL, Cancer research, 56(9), 1996, pp. 2112-2115
DETERMINATION OF PACLITAXEL AND METABOLITES IN MOUSE PLASMA, TISSUES,URINE AND FECES BY SEMIAUTOMATED REVERSED-PHASE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY
Authors: SPARREBOOM A VANTELLINGEN O NOOIJEN WJ BEIJNEN JH
Citation: A. Sparreboom et al., DETERMINATION OF PACLITAXEL AND METABOLITES IN MOUSE PLASMA, TISSUES,URINE AND FECES BY SEMIAUTOMATED REVERSED-PHASE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY, Journal of chromatography B. Biomedical applications, 664(2), 1995, pp. 383-391
MULTIPLE COURSES OF HIGH-DOSE ALKYLATING THERAPY WITH AUTOLOGOUS STEM-CELL SUPPORT
Authors: RODENHUIS S VANDERWALL E SCHORNAGEL JH HOLTKAMP M NOOIJEN WJ BAARS JW
Citation: S. Rodenhuis et al., MULTIPLE COURSES OF HIGH-DOSE ALKYLATING THERAPY WITH AUTOLOGOUS STEM-CELL SUPPORT, European journal of cancer, 31A, 1995, pp. 12-12
ISOLATION, PURIFICATION, AND BIOLOGICAL-ACTIVITY OF MONOHYDROXYLATED AND DIHYDROXYLATED PACLITAXEL METABOLITES FROM HUMAN FECES
Authors: SPARREBOOM A HUIZING MT BOESENWILLEM JJB NOOIJEN WJ VANTELLINGEN O BEIJNEN JH
Citation: A. Sparreboom et al., ISOLATION, PURIFICATION, AND BIOLOGICAL-ACTIVITY OF MONOHYDROXYLATED AND DIHYDROXYLATED PACLITAXEL METABOLITES FROM HUMAN FECES, Cancer chemotherapy and pharmacology, 36(4), 1995, pp. 299-304
HIGH-DOSE CARBOPLATIN, THIOTEPA AND CYCLOPHOSPHAMIDE (CTC) WITH PERIPHERAL-BLOOD STEM-CELL SUPPORT IN THE ADJUVANT THERAPY OF HIGH-RISK BREAST-CANCER - A PRACTICAL APPROACH
Authors: VANDERWALL E NOOIJEN WJ BAARS JW HOLTKAMP MJ SCHORNAGEL JH RICHEL DJ RUTGERS EJT SLAPERCORTENBACH ICM VANDERSCHOOT CE RODENHUIS S
Citation: E. Vanderwall et al., HIGH-DOSE CARBOPLATIN, THIOTEPA AND CYCLOPHOSPHAMIDE (CTC) WITH PERIPHERAL-BLOOD STEM-CELL SUPPORT IN THE ADJUVANT THERAPY OF HIGH-RISK BREAST-CANCER - A PRACTICAL APPROACH, British Journal of Cancer, 71(4), 1995, pp. 857-862
FULLY AUTOMATED HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC METHOD FOR THE DETERMINATION OF CARZELESIN (U-80,244) AND METABOLITES (U-76,073 ANDU-76,074) IN HUMAN PLASMA
Authors: VANTELLINGEN O PELS EM HENRAR REC SCHAAF LJ PADBURY GE BEIJNEN JH NOOIJEN WJ
Citation: O. Vantellingen et al., FULLY AUTOMATED HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC METHOD FOR THE DETERMINATION OF CARZELESIN (U-80,244) AND METABOLITES (U-76,073 ANDU-76,074) IN HUMAN PLASMA, Journal of chromatography B. Biomedical applications, 652(1), 1994, pp. 51-58
BONE-MARROW RECONSTITUTION AFTER HIGH-DOSE CHEMOTHERAPY AND AUTOLOGOUS PERIPHERAL-BLOOD PROGENITOR-CELL TRANSPLANTATION - EFFECT OF GRAFT SIZE
Authors: VANDERWALL E RICHEL DJ HOLTKAMP MJ SLAPERCORTENBACH ICM VANDERSCHOOT CE DALESIO O NOOIJEN WJ SCHORNAGEL JH RODENHUIS S
Citation: E. Vanderwall et al., BONE-MARROW RECONSTITUTION AFTER HIGH-DOSE CHEMOTHERAPY AND AUTOLOGOUS PERIPHERAL-BLOOD PROGENITOR-CELL TRANSPLANTATION - EFFECT OF GRAFT SIZE, Annals of oncology, 5(9), 1994, pp. 795-802
THE PHARMACOKINETICS OF REDUCED FOLATES AFTER INTRAPERITONEAL AND INTRAVENOUS ADMINISTRATION OF RACEMIC [6S,R]-FOLINIC ACID
Authors: SIPS JHM VANTELLINGEN O NOOIJEN WJ RODENHUIS S HUININK WWT BEIJNEN JH
Citation: Jhm. Sips et al., THE PHARMACOKINETICS OF REDUCED FOLATES AFTER INTRAPERITONEAL AND INTRAVENOUS ADMINISTRATION OF RACEMIC [6S,R]-FOLINIC ACID, Cancer chemotherapy and pharmacology, 35(2), 1994, pp. 144-148
PLASMA PHARMACOKINETICS, TISSUE DISPOSITION, EXCRETION AND METABOLISMOF VINLEUCINOL IN MICE AS DETERMINED BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY
Authors: VANTELLINGEN O SONNEVELDT ALC BEIJNEN JH NOOIJEN WJ KETTENESVANDENBOSCH JJ VERSLUIS C BULT A
Citation: O. Vantellingen et al., PLASMA PHARMACOKINETICS, TISSUE DISPOSITION, EXCRETION AND METABOLISMOF VINLEUCINOL IN MICE AS DETERMINED BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY, Cancer chemotherapy and pharmacology, 33(5), 1994, pp. 425-434
TISSUE DISPOSITION, EXCRETION AND METABOLISM OF VINBLASTINE IN MICE AS DETERMINED BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY
Authors: VANTELLINGEN O BEIJNEN JH NOOIJEN WJ BULT A
Citation: O. Vantellingen et al., TISSUE DISPOSITION, EXCRETION AND METABOLISM OF VINBLASTINE IN MICE AS DETERMINED BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY, Cancer chemotherapy and pharmacology, 32(4), 1993, pp. 286-292
PLASMA PHARMACOKINETICS, TISSUE DISPOSITION, EXCRETION AND METABOLISMOF VINORELBINE IN MICE AS DETERMINED BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY
Authors: VANTELLINGEN O KUIJPERS AV BEIJNEN JH NOOIJEN WJ BULT A
Citation: O. Vantellingen et al., PLASMA PHARMACOKINETICS, TISSUE DISPOSITION, EXCRETION AND METABOLISMOF VINORELBINE IN MICE AS DETERMINED BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY, Investigational new drugs, 11(2-3), 1993, pp. 141-150
Risultati: 1-25 | 26-26