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Results: 1-20 |
Results: 20
BIOLOGIC ACTIVITY OF LIPOPHILIC 1-B-D-ARABINOFURANOSYLCYTOSINE (ARA-C) DERIVATIVES - CELL-SPECIFIC CYTOTOXICITY AND STRUCTURE-ACTIVITY RELATIONSHIP (SAR)
Authors: VOORN DA KUIPER CM NOORDHUIS P SMID K SANDVOLD ML MYHREN F HENDRIKS HR PETERS GJ
Citation: Da. Voorn et al., BIOLOGIC ACTIVITY OF LIPOPHILIC 1-B-D-ARABINOFURANOSYLCYTOSINE (ARA-C) DERIVATIVES - CELL-SPECIFIC CYTOTOXICITY AND STRUCTURE-ACTIVITY RELATIONSHIP (SAR), Annals of oncology, 9, 1998, pp. 119-119
INVESTIGATIONS OF MODULATION OF 5-FLUOROURACIL (FU) PHARMACOKINETICS BY 5-ETHYL-2'-DEOXYURIDINE (EUDR) IN TUMOR-BEARING MICE AND RATS
Authors: MCSHEEHY P KRALOVANSKY J JENEY A PANDI E KATONA C NOORDHUIS P PETERS G RODRIGUES L GRIFFITHS J
Citation: P. Mcsheehy et al., INVESTIGATIONS OF MODULATION OF 5-FLUOROURACIL (FU) PHARMACOKINETICS BY 5-ETHYL-2'-DEOXYURIDINE (EUDR) IN TUMOR-BEARING MICE AND RATS, Annals of oncology, 9, 1998, pp. 581-581
EXPRESSION OF MESSENGER-RNA ENCODING FOR THE REDUCED FOLATE CARRIER AND FOLATE METABOLIZING ENZYMES IN CHILDHOOD LEUKEMIA-CELLS AS MEASUREDWITH A COMPETITIVE TEMPLATE RT-PCR METHOD
Authors: ROTS MG NOORDHUIS P WILLEY JC VANZANTWIJK CH DEMUTH JP VEERMAN AJP PIETERS R PETERS GJ JANSEN G
Citation: Mg. Rots et al., EXPRESSION OF MESSENGER-RNA ENCODING FOR THE REDUCED FOLATE CARRIER AND FOLATE METABOLIZING ENZYMES IN CHILDHOOD LEUKEMIA-CELLS AS MEASUREDWITH A COMPETITIVE TEMPLATE RT-PCR METHOD, Annals of oncology, 9, 1998, pp. 620-620
MODULATION OF RESISTANCE TO ARA-C BY BRYOSTATIN IN FRESH BLAST CELLS FROM PATIENTS WITH AML
Authors: ELGIE AW SARGENT JM ALTON P PETERS GJ NOORDHUIS P WILLIAMSON CJ TAYLOR CG
Citation: Aw. Elgie et al., MODULATION OF RESISTANCE TO ARA-C BY BRYOSTATIN IN FRESH BLAST CELLS FROM PATIENTS WITH AML, Leukemia research, 22(4), 1998, pp. 373-378
A STRUCTURALLY ALTERED HUMAN REDUCED FOLATE CARRIER WITH INCREASED FOLIC-ACID TRANSPORT MEDIATES A NOVEL MECHANISM OF ANTIFOLATE RESISTANCE
Authors: JANSEN G MAURITZ R DRORI S SPRECHER H KATHMANN I BUNNI M PRIEST DG NOORDHUIS P SCHORNAGEL JH PINEDO HM PETERS GJ ASSARAF YG
Citation: G. Jansen et al., A STRUCTURALLY ALTERED HUMAN REDUCED FOLATE CARRIER WITH INCREASED FOLIC-ACID TRANSPORT MEDIATES A NOVEL MECHANISM OF ANTIFOLATE RESISTANCE, The Journal of biological chemistry, 273(46), 1998, pp. 30189-30198
MODULATION OF 5-FLUOROURACIL IN MICE USING URIDINE DIPHOSPHOGLUCOSE
Authors: CODACCIPISANELLI G KRALOVANSZKY J VANDERWILT CL NOORDHUIS P COLOFIORE JR MARTIN DS FRANCHI F PETERS GJ
Citation: G. Codaccipisanelli et al., MODULATION OF 5-FLUOROURACIL IN MICE USING URIDINE DIPHOSPHOGLUCOSE, Clinical cancer research, 3(2), 1997, pp. 309-315
A PHASE-I STUDY WITH S-1, AN ORAL 5-FU FORMULATION, IN PATIENTS WITH SOLID TUMORS
Authors: VANGROENINGEN CJ SCHORNAGEL JH PETERS GJ NOORDHUIS P VANKUILENBURG ABP SHIRASAKA T SHIMAMURA Y DEVRIES MJ HANAUSKE AR
Citation: Cj. Vangroeningen et al., A PHASE-I STUDY WITH S-1, AN ORAL 5-FU FORMULATION, IN PATIENTS WITH SOLID TUMORS, European journal of cancer, 33, 1997, pp. 1104-1104
BIOCHEMICAL-MECHANISMS OF INTERFERON MODULATION OF 5-FLUOROURACIL ACTIVITY IN COLON-CANCER CELLS
Authors: VANDERWILT CL SMID K AHERNE GW NOORDHUIS P PETERS GJ
Citation: Cl. Vanderwilt et al., BIOCHEMICAL-MECHANISMS OF INTERFERON MODULATION OF 5-FLUOROURACIL ACTIVITY IN COLON-CANCER CELLS, European journal of cancer, 33(3), 1997, pp. 471-478
THERAPEUTIC EFFICACY OF FLUOROPYRIMIDINES DEPENDS ON THE DURATION OF THYMIDYLATE SYNTHASE INHIBITION IN THE MURINE COLON 26-B CARCINOMA TUMOR-MODEL
Authors: VANLAAR JAM VANDERWILT CL RUSTUM YM NOORDHUIS P SMID K PINEDO HM PETERS GJ
Citation: Jam. Vanlaar et al., THERAPEUTIC EFFICACY OF FLUOROPYRIMIDINES DEPENDS ON THE DURATION OF THYMIDYLATE SYNTHASE INHIBITION IN THE MURINE COLON 26-B CARCINOMA TUMOR-MODEL, Clinical cancer research, 2(8), 1996, pp. 1327-1333
ANTITUMOR-ACTIVITY OF PROLONGED AS COMPARED WITH BOLUS ADMINISTRATIONOF 2',2'-DIFLUORODEOXYCYTIDINE IN-VIVO AGAINST MURINE COLON TUMORS
Authors: VEERMAN G VANHAPEREN VWTR VERMORKEN JB NOORDHUIS P BRAAKHUIS BJM PINEDO HM PETERS GJ
Citation: G. Veerman et al., ANTITUMOR-ACTIVITY OF PROLONGED AS COMPARED WITH BOLUS ADMINISTRATIONOF 2',2'-DIFLUORODEOXYCYTIDINE IN-VIVO AGAINST MURINE COLON TUMORS, Cancer chemotherapy and pharmacology, 38(4), 1996, pp. 335-342
MODULATION OF METABOLISM AND CYTOTOXICITY OF CYTOSINE-ARABINOSIDE WITH N-(PHOSPHON)-ACETYL-L-ASPARTATE IN HUMAN LEUKEMIC BLAST CELLS AND CELL-LINES
Authors: NOORDHUIS P KAZEMIER KM KASPERS GJL PETERS GJ
Citation: P. Noordhuis et al., MODULATION OF METABOLISM AND CYTOTOXICITY OF CYTOSINE-ARABINOSIDE WITH N-(PHOSPHON)-ACETYL-L-ASPARTATE IN HUMAN LEUKEMIC BLAST CELLS AND CELL-LINES, Leukemia research, 20(2), 1996, pp. 127-134
INTERMITTENT CONTINUOUS-INFUSION OF 5-FLUOROURACIL AND LOW-DOSE ORAL LEUCOVORIN IN PATIENTS WITH GASTROINTESTINAL CANCER - RELATIONSHIP BETWEEN PLASMA-CONCENTRATIONS AND CLINICAL-PARAMETERS
Authors: POORTER RL PETERS GJ BAKKER PJM TAAT CW BIERMANSVANLEEUWE DMJ CODACCIPISANELLI G NOORDHUIS P OOSTING J VEENHOF CHN
Citation: Rl. Poorter et al., INTERMITTENT CONTINUOUS-INFUSION OF 5-FLUOROURACIL AND LOW-DOSE ORAL LEUCOVORIN IN PATIENTS WITH GASTROINTESTINAL CANCER - RELATIONSHIP BETWEEN PLASMA-CONCENTRATIONS AND CLINICAL-PARAMETERS, European journal of cancer, 31A(9), 1995, pp. 1465-1470
ANTITUMOR-ACTIVITY, TOXICITY AND INHIBITION OF THYMIDYLATE SYNTHASE OF PROLONGED ADMINISTRATION OF 5-FLUOROURACIL IN MICE
Authors: CODACCIPISANELLI G VANDERWILT CL PINEDO HM FRANCHI F NOORDHUIS P BRAAKHUIS BJM VANLAAR JAM PETERS GJ
Citation: G. Codaccipisanelli et al., ANTITUMOR-ACTIVITY, TOXICITY AND INHIBITION OF THYMIDYLATE SYNTHASE OF PROLONGED ADMINISTRATION OF 5-FLUOROURACIL IN MICE, European journal of cancer, 31A(9), 1995, pp. 1517-1525
CIRCADIAN VARIATION OF DIHYDROPYRIMIDINE DEHYDROGENASE (DPD), URIDINEPHOSPHORYLASE (UP), BETA-ALANINE (BETA-ALA) AND 5-FLUOROURACIL, (5-FU) DURING CONTINOUS INFUSION (CI) FLUOROPYRIMIDINES (FP)
Authors: VANKUILENBURG ABP POORTER RL PETERS GJ VANLENTHE H STROOMER AEM VANGENNIP AH SMID K NOORDHUIS P BAKKER PJM VEENHOF CHN
Citation: Abp. Vankuilenburg et al., CIRCADIAN VARIATION OF DIHYDROPYRIMIDINE DEHYDROGENASE (DPD), URIDINEPHOSPHORYLASE (UP), BETA-ALANINE (BETA-ALA) AND 5-FLUOROURACIL, (5-FU) DURING CONTINOUS INFUSION (CI) FLUOROPYRIMIDINES (FP), European journal of cancer, 31A, 1995, pp. 954-954
QUANTIFICATION OF 5-FLUOROURACIL INCORPORATION INTO RNA OF HUMAN AND MURINE TUMORS AS MEASURED WITH A SENSITIVE GAS-CHROMATOGRAPHY MASS-SPECTROMETRY ASSAY
Authors: PETERS GJ NOORDHUIS P KOMISSAROV A HOLWERDA U KOK RM VANLAAR JAM VANDERWILT CL VANGROENINGEA CJ PINEDO HM
Citation: Gj. Peters et al., QUANTIFICATION OF 5-FLUOROURACIL INCORPORATION INTO RNA OF HUMAN AND MURINE TUMORS AS MEASURED WITH A SENSITIVE GAS-CHROMATOGRAPHY MASS-SPECTROMETRY ASSAY, Analytical biochemistry, 231(1), 1995, pp. 157-163
SCHEDULE DEPENDENCE OF SENSITIVITY TO 2',2'-DIFLUORODEOXYCYTIDINE (GEMCITABINE) IN RELATION TO ACCUMULATION AND RETENTION OF ITS TRIPHOSPHATE IN SOLID TUMOR-CELL LINES AND SOLID TUMORS
Authors: VANHAPEREN VWTR VEERMAN G BOVEN E NOORDHUIS P VERMORKEN JB PETERS GJ
Citation: Vwtr. Vanhaperen et al., SCHEDULE DEPENDENCE OF SENSITIVITY TO 2',2'-DIFLUORODEOXYCYTIDINE (GEMCITABINE) IN RELATION TO ACCUMULATION AND RETENTION OF ITS TRIPHOSPHATE IN SOLID TUMOR-CELL LINES AND SOLID TUMORS, Biochemical pharmacology, 48(7), 1994, pp. 1327-1339
TRANSFORMATION OF MOUSE FIBROBLASTS WITH THE ONCOGENES H-RAS OR TRK IS ASSOCIATED WITH PRONOUNCED CHANGES IN DRUG SENSITIVITY AND METABOLISM
Authors: PETERS GJ WETS M KEEPERS YPAM OSKAM R VANARKOTTE J NOORDHUIS P SMID K PINEDO HM
Citation: Gj. Peters et al., TRANSFORMATION OF MOUSE FIBROBLASTS WITH THE ONCOGENES H-RAS OR TRK IS ASSOCIATED WITH PRONOUNCED CHANGES IN DRUG SENSITIVITY AND METABOLISM, International journal of cancer, 54(3), 1993, pp. 450-455
IN-VITRO ANTITUMOR-ACTIVITY OF CIS-5-FLUORO-5,6-DIHYDRO-6-ALKOXY-URACIL AND TRANS-5-FLUORO-5,6-DIHYDRO-6-ALKOXY-URACIL - EFFECTS ON THYMIDYLATE SYNTHESIS
Authors: VANDERWILT CL VISSER GWM BRAAKHUIS BJM WEDZINGA R NOORDHUIS P SMID K PETERS GJ
Citation: Cl. Vanderwilt et al., IN-VITRO ANTITUMOR-ACTIVITY OF CIS-5-FLUORO-5,6-DIHYDRO-6-ALKOXY-URACIL AND TRANS-5-FLUORO-5,6-DIHYDRO-6-ALKOXY-URACIL - EFFECTS ON THYMIDYLATE SYNTHESIS, British Journal of Cancer, 68(4), 1993, pp. 702-707
IMPORTANCE OF PHARMACODYNAMICS IN THE IN-VITRO ANTIPROLIFERATIVE ACTIVITY OF THE ANTIFOLATES METHOTREXATE AND 10-ETHYL-10-DEAZAAMINOPTERIN AGAINST HUMAN HEAD AND NECK SQUAMOUS-CELL CARCINOMA
Authors: BRAAKHUIS BJM JANSEN G NOORDHUIS P KEGEL A PETERS GJ
Citation: Bjm. Braakhuis et al., IMPORTANCE OF PHARMACODYNAMICS IN THE IN-VITRO ANTIPROLIFERATIVE ACTIVITY OF THE ANTIFOLATES METHOTREXATE AND 10-ETHYL-10-DEAZAAMINOPTERIN AGAINST HUMAN HEAD AND NECK SQUAMOUS-CELL CARCINOMA, Biochemical pharmacology, 46(12), 1993, pp. 2155-2161
DETERMINATION OF THE ANTIMETABOLITE GEMCITABINE (2',2'-DIFLUORO-2'-DEOXYCYTIDINE) AND OF 2',2'-DIFLUORO-2'-DEOXYURIDINE BY F-19 NUCLEAR-MAGNETIC-RESONANCE SPECTROSCOPY
Authors: EDZES HT PETERS GJ NOORDHUIS P VERMORKEN JB
Citation: Ht. Edzes et al., DETERMINATION OF THE ANTIMETABOLITE GEMCITABINE (2',2'-DIFLUORO-2'-DEOXYCYTIDINE) AND OF 2',2'-DIFLUORO-2'-DEOXYURIDINE BY F-19 NUCLEAR-MAGNETIC-RESONANCE SPECTROSCOPY, Analytical biochemistry, 214(1), 1993, pp. 25-30
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