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Results: 1-14 |
Results: 14
Stereochemistry control in the Lewis acid mediated lactonization reaction of gamma,delta-epoxy-beta-silyloxy esters
Authors: Nacro, K Gorrichon, L Escudier, JM Baltas, M
Citation: K. Nacro et al., Stereochemistry control in the Lewis acid mediated lactonization reaction of gamma,delta-epoxy-beta-silyloxy esters, EUR J ORG C, (22), 2001, pp. 4247-4258
Discovery of small-molecule inhibitors of bcl-2 through structure-based computer screening
Authors: Enyedy, IJ Ling, Y Nacro, K Tomita, Y Wu, XH Cao, YY Guo, RB Li, BH Zhu, XF Huang, Y Long, YQ Roller, PP Yang, DJ Wang, SM
Citation: Ij. Enyedy et al., Discovery of small-molecule inhibitors of bcl-2 through structure-based computer screening, J MED CHEM, 44(25), 2001, pp. 4313-4324
An optimized protein kinase C activating diacylglycerol combining high binding affinity (K-i) with reduced lipophilicity (log P)
Authors: Nacro, K Sigano, DM Yan, SQ Nicklaus, MC Pearce, LL Lewin, NE Garfield, SH Blumberg, PM Marquez, VE
Citation: K. Nacro et al., An optimized protein kinase C activating diacylglycerol combining high binding affinity (K-i) with reduced lipophilicity (log P), J MED CHEM, 44(12), 2001, pp. 1892-1904
Role of hydrophobic residues in the C1b domain of protein kinase C delta on ligand and phospholipid interactions
Authors: Wang, QMJ Fang, TW Nacro, K Marquez, VE Wang, SM Blumberg, PM
Citation: Qmj. Wang et al., Role of hydrophobic residues in the C1b domain of protein kinase C delta on ligand and phospholipid interactions, J BIOL CHEM, 276(22), 2001, pp. 19580-19587
Diacylglycerols with lipophilically equivalent branched acyl chains display high affinity for protein kinase C (PK-C). A direct measure of the effectof constraining the glycerol backbone in DAG lactones
Authors: Nacro, K Bienfait, B Lewin, NE Blumberg, PM Marquez, VE
Citation: K. Nacro et al., Diacylglycerols with lipophilically equivalent branched acyl chains display high affinity for protein kinase C (PK-C). A direct measure of the effectof constraining the glycerol backbone in DAG lactones, BIOORG MED, 10(7), 2000, pp. 653-655
Diacylglycerols with lipophilically equivalent branched acyl chains display high affinity for protein kinase C (PK-C). A direct measure of the effectof constraining the glycerol backbone in DAG lactones (vol 10, pg 653, 2000)
Authors: Nacro, K Bienfait, B Lewin, NE Blumberg, PM Marquez, VE
Citation: K. Nacro et al., Diacylglycerols with lipophilically equivalent branched acyl chains display high affinity for protein kinase C (PK-C). A direct measure of the effectof constraining the glycerol backbone in DAG lactones (vol 10, pg 653, 2000), BIOORG MED, 10(12), 2000, pp. 1401-1401
Conformationally constrained analogues of diacylglycerol (DAG). 16. How much structural complexity is necessary for recognition and high binding affinity to protein kinase C?
Authors: Nacro, K Bienfait, B Lee, J Han, KC Kang, JH Benzaria, S Lewin, NE Bhattacharyya, DK Blumberg, PM Marquez, VE
Citation: K. Nacro et al., Conformationally constrained analogues of diacylglycerol (DAG). 16. How much structural complexity is necessary for recognition and high binding affinity to protein kinase C?, J MED CHEM, 43(5), 2000, pp. 921-944
Conformationally constrained analogues of diacylglycerol (DAG). 17. Contrast between sn-1 and sn-2 DAG lactones in binding to protein kinase C
Authors: Tamamura, H Bienfait, B Nacro, K Lewin, NE Blumberg, PM Marquez, VE
Citation: H. Tamamura et al., Conformationally constrained analogues of diacylglycerol (DAG). 17. Contrast between sn-1 and sn-2 DAG lactones in binding to protein kinase C, J MED CHEM, 43(17), 2000, pp. 3209-3217
The transition from a pharmacophore-guided approach to a receptor-guided approach in the design of potent protein kinase C ligands
Authors: Marquez, VE Nacro, K Benzaria, S Lee, J Sharma, R Teng, K Milne, GWA Bienfait, B Wang, SM Lewin, NE Blumberg, PM
Citation: Ve. Marquez et al., The transition from a pharmacophore-guided approach to a receptor-guided approach in the design of potent protein kinase C ligands, PHARM THERA, 82(2-3), 1999, pp. 251-261
Attempt to rationalize the diastereoselectivity in the addition of ester enolate to optically active alpha,beta-epoxyaldehydes
Authors: Nacro, K Baltas, M Gorrichon, L
Citation: K. Nacro et al., Attempt to rationalize the diastereoselectivity in the addition of ester enolate to optically active alpha,beta-epoxyaldehydes, TETRAHEDRON, 55(49), 1999, pp. 14013-14030
Lactonisation and lactone ether formation of nerol geraniol compounds. Useof C-13 to identify the cyclisation process
Authors: Nacro, K Baltas, M Zedde, C Gorrichon, L Jaud, J
Citation: K. Nacro et al., Lactonisation and lactone ether formation of nerol geraniol compounds. Useof C-13 to identify the cyclisation process, TETRAHEDRON, 55(16), 1999, pp. 5129-5138
beta 2-chimaerin is a novel target for diacylglycerol: Binding properties and changes in subcellular localization mediated by ligand binding to its C1 domain
Authors: Caloca, MJ Garcia-Bermejo, ML Blumberg, PM Lewin, NE Kremmer, E Mischak, H Wang, SM Nacro, K Bienfait, B Marquez, VE Kazanietz, MG
Citation: Mj. Caloca et al., beta 2-chimaerin is a novel target for diacylglycerol: Binding properties and changes in subcellular localization mediated by ligand binding to its C1 domain, P NAS US, 96(21), 1999, pp. 11854-11859
Differential localization of protein kinase C delta by phorbol esters and related compounds using a fusion protein with green fluorescent protein
Authors: Wang, QMJ Bhattacharyya, D Garfield, S Nacro, K Marquez, VE Blumberg, PM
Citation: Qmj. Wang et al., Differential localization of protein kinase C delta by phorbol esters and related compounds using a fusion protein with green fluorescent protein, J BIOL CHEM, 274(52), 1999, pp. 37233-37239
Conformationally constrained analogues of diacylglycerol (DAG). 15. The indispensable role of the sn-1 and sn-2 carbonyls in the binding of DAG-lactones to protein kinase C (PK-C)
Authors: Benzaria, S Bienfait, B Nacro, K Wang, SM Lewin, NE Beheshti, M Blumberg, PM Marquez, VE
Citation: S. Benzaria et al., Conformationally constrained analogues of diacylglycerol (DAG). 15. The indispensable role of the sn-1 and sn-2 carbonyls in the binding of DAG-lactones to protein kinase C (PK-C), BIOORG MED, 8(23), 1998, pp. 3403-3408
Risultati: 1-14 |