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Results: 1-25/27
Authors:
Ruhl, R
Thiel, R
Lacker, TS
Strohschein, S
Albert, K
Nau, H
Citation: R. Ruhl et al., Synthesis, high-performance liquid chromatography-nuclear magnetic resonance characterization and pharmacokinetics in mice of CD271 glucuronide, J CHROMAT B, 757(1), 2001, pp. 101-109
Authors:
Tzimas, G
Nau, H
Citation: G. Tzimas et H. Nau, The role of metabolism and toxicokinetics in retinoid teratogenesis, CUR PHARM D, 7(9), 2001, pp. 803-831
Authors:
Lampen, A
Gottlicher, M
Nau, H
Citation: A. Lampen et al., Prediction of embryotoxic effects of valproic acid-derivatives with molecular in vitro methods, ALTEX-AL TI, 18(2), 2001, pp. 123-126
Authors:
Tzimas, G
Nau, H
Citation: G. Tzimas et H. Nau, Vitamin A teratogenicity and risk assessment in the macaque retinoid model, REPROD TOX, 15(4), 2001, pp. 445-446
Authors:
Ruhl, R
Sass, JO
Nau, H
Klug, S
Citation: R. Ruhl et al., Effects of all-trans-retinoic acid and all-trans-retinoyl glucuronide in two in vitro systems of distinct biological complexity, ARCH TOXIC, 75(8), 2001, pp. 497-504
Authors:
Nau, H
Citation: H. Nau, Teratogenicity of isotretinoin revisited: Species variation and the role of all-trans-retinoic acid, J AM ACAD D, 45(5), 2001, pp. S183-S187
Authors:
Lampen, A
Meyer, S
Nau, H
Citation: A. Lampen et al., Phytanic acid and docosahexaenoic acid increase the metabolism of all-trans-retinoic acid and CYP26 gene expression in intestinal cells, BBA-GENE ST, 1521(1-3), 2001, pp. 97-106
Authors:
Lampen, A
Meyer, S
Nau, H
Citation: A. Lampen et al., Effects of receptor-selective retinoids on CYP26 gene expression and metabolism of all-trans-retinoic acid in intestinal cells, DRUG META D, 29(5), 2001, pp. 742-747
Authors:
Elmazar, MMA
Ruhl, R
Nau, H
Citation: Mma. Elmazar et al., Synergistic teratogenic effects induced by retinoids in mice by coadministration of a RAR alpha- or RAR gamma-selective agonist with a RXR-selective agonist, TOX APPL PH, 170(1), 2001, pp. 2-9
Authors:
Werling, U
Siehler, S
Litfin, M
Nau, H
Gottlicher, M
Citation: U. Werling et al., Induction of differentiation in F9 cells and activation of peroxisome proliferator-activated receptor delta by valproic acid and its teratogenic derivatives, MOLEC PHARM, 59(5), 2001, pp. 1269-1276
Authors:
Murphy, KJ
Fox, GB
Foley, AG
Gallagher, HC
O'Connell, A
Griffin, AM
Nau, H
Regan, CM
Citation: Kj. Murphy et al., Pentyl-4-yn-valproic acid enhances both spatial and avoidance learning, and attenuates age-related NCAM-mediated neuroplastic decline within the rat medial temporal lobe, J NEUROCHEM, 78(4), 2001, pp. 704-714
Authors:
Lampen, A
Carlberg, C
Nau, H
Citation: A. Lampen et al., Peroxisome proliferator-activated receptor delta is a specific sensor for teratogenic valproic acid derivatives, EUR J PHARM, 431(1), 2001, pp. 25-33
Authors:
Hamscher, G
Sczesny, S
Abu-Qare, A
Hoper, H
Nau, H
Citation: G. Hamscher et al., Substances with pharmacological effects including hormonally active substances in the environment: Identification of tetracyclines in soil fertilizedwith animal slurry., DEUT TIER W, 107(8), 2000, pp. 332-334
Authors:
Kratke, R
Ruhl, R
Kirschbaum, F
Nau, H
Citation: R. Kratke et al., All-trans-retinoic acid and all-trans-retinoyl-beta-D-glucuronide alter the development of axolotl embryos (Ambystoma mexicanum) in vitro, ARCH TOXIC, 74(3), 2000, pp. 173-180
Authors:
Arafa, HMM
Elmazar, MMA
Hamada, FMA
Reichert, U
Shroot, B
Nau, H
Citation: Hmm. Arafa et al., Selective agonists of retinoic acid receptors: comparative toxicokinetics and embryonic exposure, ARCH TOXIC, 73(10-11), 2000, pp. 547-556
Authors:
Chen, WC
Sass, JO
Seltmann, H
Nau, H
Orfanos, CE
Zouboulis, CC
Citation: Wc. Chen et al., Biological effects and metabolism of 9-cis-retinoic acid and its metabolite 9,13-di-cis-retinoic acid in HaCaT keratinocytes in vitro: comparison with all-trans-retinoic acid, ARCH DERM R, 292(12), 2000, pp. 612-620
Authors:
Nilsson, CB
Hoegberg, P
Trossvik, C
Azais-Braesco, V
Blaner, WS
Fex, G
Harrison, EH
Nau, H
Schmidt, CK
van Bennekum, AM
Hakansson, H
Citation: Cb. Nilsson et al., 2,3,7,8-tetrachlorodibenzo-p-dioxin increases serum and kidney retinoic acid levels and kidney retinol esterification in the rat, TOX APPL PH, 169(2), 2000, pp. 121-131
Authors:
Lampen, A
Meyer, S
Arnhold, T
Nau, H
Citation: A. Lampen et al., Metabolism of vitamin A and its active metabolite all-trans retinoic acid in small intestinal enterocytes, J PHARM EXP, 295(3), 2000, pp. 979-985
Authors:
Didierjean, L
Sass, JO
Carraux, P
Grand, D
Sorg, O
Plum, C
Nau, H
Saurat, JH
Citation: L. Didierjean et al., Topical 9-cis-retinaldehyde for delivery of 9-cis-retinoic acid in mouse skin, EXP DERMATO, 8(3), 1999, pp. 199-203
Authors:
Spiegelstein, O
Bialer, M
Radatz, M
Nau, H
Yagen, B
Citation: O. Spiegelstein et al., Enantioselective synthesis and teratogenicity of propylisopropyl acetamide, a CNS-active chiral amide analogue of valproic acid, CHIRALITY, 11(8), 1999, pp. 645-650
Authors:
Dolk, HM
Nau, H
Hummler, H
Barlow, SM
Citation: Hm. Dolk et al., Dietary vitamin A and teratogenic risk: European Teratology Society discussion paper, EUR J OB GY, 83(1), 1999, pp. 31-36
Authors:
Sass, JO
Tzimas, G
Elmazar, MMA
Nau, H
Citation: Jo. Sass et al., Metabolism of retinaldehyde isomers in pregnant rats: 13-cis- and all-trans-retinaldehyde, but not 9-cis-retinaldehyde, yield very similar patterns of retinoid metabolites, DRUG META D, 27(3), 1999, pp. 317-321
Authors:
Lampen, A
Siehler, S
Ellerbeck, U
Gottlicher, M
Nau, H
Citation: A. Lampen et al., New molecular bioassays for the estimation of the teratogenic potency of valproic acid derivatives in vitro: Activation of the peroxisomal proliferator-activated receptor (PPAR delta), TOX APPL PH, 160(3), 1999, pp. 238-249
Authors:
Konig, SA
Elger, CE
Vasella, F
Schmidt, D
Bergmann, A
Boenigk, HE
Despland, PA
Genton, P
Kramer, G
Loscher, W
Mayer, T
Nau, H
Schneble, H
Siemes, H
Stefan, H
Wolf, P
Citation: Sa. Konig et al., Blood laboratory tests and clinical monitoring recommended for early detection of valproate associated liver failure, MONATS KIND, 147(8), 1999, pp. 718-723
Authors:
Zouboulis, CC
Seltmann, H
Sass, JO
Ruhl, R
Plum, C
Hettmannsperger, U
Blume-Peytavi, U
Nau, H
Orfanos, CE
Citation: Cc. Zouboulis et al., Retinoid signaling by all-trans retinoic acid and all-trans retinoyl-beta-D-glucuronide is attenuated by simultaneous exposure of human keratinocytesto retinol, J INVES DER, 112(2), 1999, pp. 157-164