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Results: 1-25 | 26-27
Results: 1-25/27
Protein synthesis - The perks of balancing glucose
Authors: Sonenberg, N Newgard, CB
Citation: N. Sonenberg et Cb. Newgard, Protein synthesis - The perks of balancing glucose, SCIENCE, 293(5531), 2001, pp. 818-819
Control of hepatic gluconeogenesis through the transcriptional coactivatorPGC-1
Authors: Yoon, JC Puigserver, P Chen, GX Donovan, J Wu, ZD Rhee, J Adelmant, G Stafford, J Kahn, CR Granner, DK Newgard, CB Spiegelman, BM
Citation: Jc. Yoon et al., Control of hepatic gluconeogenesis through the transcriptional coactivatorPGC-1, NATURE, 413(6852), 2001, pp. 131-138
Overexpression of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase in mouse liver lowers blood glucose by suppressing hepatic glucose production
Authors: Wu, CD Okar, DA Newgard, CB Lange, A
Citation: Cd. Wu et al., Overexpression of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase in mouse liver lowers blood glucose by suppressing hepatic glucose production, J CLIN INV, 107(1), 2001, pp. 91-98
Overexpression of a modified human malonyl-CoA decarboxylase blocks the glucose-induced increase in malonyl-CoA level but has no impact on insulin secretion in INS-1-derived (832/13) beta-cells
Authors: Mulder, H Lu, DH Finley, J An, J Cohen, J Antinozzi, PA McGarry, JD Newgard, CB
Citation: H. Mulder et al., Overexpression of a modified human malonyl-CoA decarboxylase blocks the glucose-induced increase in malonyl-CoA level but has no impact on insulin secretion in INS-1-derived (832/13) beta-cells, J BIOL CHEM, 276(9), 2001, pp. 6479-6484
Overexpression of the P46 (T1) translocase component of the glucose-6-phosphatase complex in hepatocytes impairs glycogen accumulation via hydrolysisof glucose 1-phosphate
Authors: An, J Li, YZ van de Werve, G Newgard, CB
Citation: J. An et al., Overexpression of the P46 (T1) translocase component of the glucose-6-phosphatase complex in hepatocytes impairs glycogen accumulation via hydrolysisof glucose 1-phosphate, J BIOL CHEM, 276(14), 2001, pp. 10722-10729
Expression of the transcription factor STAT-1 alpha in insulinoma cells protects against cytotoxic effects of multiple cytokines
Authors: Chen, GX Hohmeier, HE Newgard, CB
Citation: Gx. Chen et al., Expression of the transcription factor STAT-1 alpha in insulinoma cells protects against cytotoxic effects of multiple cytokines, J BIOL CHEM, 276(1), 2001, pp. 766-772
Correction of diet-induced hyperglycemia, hyperinsulinemia, and skeletal muscle insulin resistance by moderate hyperleptinemia
Authors: Buettner, R Newgard, CB Rhodes, CJ O'Doherty, RM
Citation: R. Buettner et al., Correction of diet-induced hyperglycemia, hyperinsulinemia, and skeletal muscle insulin resistance by moderate hyperleptinemia, AM J P-ENDO, 278(3), 2000, pp. E563-E569
Activation of direct and indirect pathways of glycogen synthesis by hepatic overexpression of protein targeting to glycogen
Authors: O'Doherty, RM Jensen, PB Anderson, P Jones, JG Berman, HK Kearney, D Newgard, CB
Citation: Rm. O'Doherty et al., Activation of direct and indirect pathways of glycogen synthesis by hepatic overexpression of protein targeting to glycogen, J CLIN INV, 105(4), 2000, pp. 479-488
Glucose activates mitogen-activated protein kinase (extracellular signal-regulated kinase) through proline-rich tyrosine kinase-2 and the glut1 glucose transporter
Authors: Bandyopadhyay, G Sajan, MP Kanoh, Y Standaert, ML Burke, TR Quon, MJ Reed, BC Dikic, I Noel, LE Newgard, CB Farese, R
Citation: G. Bandyopadhyay et al., Glucose activates mitogen-activated protein kinase (extracellular signal-regulated kinase) through proline-rich tyrosine kinase-2 and the glut1 glucose transporter, J BIOL CHEM, 275(52), 2000, pp. 40817-40826
Overexpression of protein targeting to glycogen in cultured human muscle cells stimulates glycogen synthesis independent of glycogen and glucose 6-phosphate levels
Authors: Lerin, C Montell, E Berman, HK Newgard, CB Gomez-Foix, AM
Citation: C. Lerin et al., Overexpression of protein targeting to glycogen in cultured human muscle cells stimulates glycogen synthesis independent of glycogen and glucose 6-phosphate levels, J BIOL CHEM, 275(51), 2000, pp. 39991-39995
Glucose down-regulates the expression of the peroxisome proliferator-activated receptor-alpha gene in the pancreatic beta-cell
Authors: Roduit, R Morin, J Masse, F Segall, L Roche, E Newgard, CB Assimacopoulos-Jeannet, F Prentki, M
Citation: R. Roduit et al., Glucose down-regulates the expression of the peroxisome proliferator-activated receptor-alpha gene in the pancreatic beta-cell, J BIOL CHEM, 275(46), 2000, pp. 35799-35806
Distinctive regulatory and metabolic properties of glycogen-targeting subunits of protein phosphatase-1 (PTG, G(L), G(M)/R-G1) expressed in hepatocytes
Authors: Gasa, R Jensen, PB Berman, HK Brady, MJ DePaoli-Roach, AA Newgard, CB
Citation: R. Gasa et al., Distinctive regulatory and metabolic properties of glycogen-targeting subunits of protein phosphatase-1 (PTG, G(L), G(M)/R-G1) expressed in hepatocytes, J BIOL CHEM, 275(34), 2000, pp. 26396-26403
Selection of insulinoma cell lines with resistance to interleukin-1 beta- and gamma-interferon-induced cytotoxicity
Authors: Chen, GX Hohmeier, HE Gasa, R Tran, VV Newgard, CB
Citation: Gx. Chen et al., Selection of insulinoma cell lines with resistance to interleukin-1 beta- and gamma-interferon-induced cytotoxicity, DIABETES, 49(4), 2000, pp. 562-570
Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion
Authors: Hohmeier, HE Mulder, H Chen, GX Henkel-Rieger, R Prentki, M Newgard, CB
Citation: He. Hohmeier et al., Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion, DIABETES, 49(3), 2000, pp. 424-430
Organizing glucose disposal - Emerging roles of the glycogen targeting subunits of protein phosphatase-1
Authors: Newgard, CB Brady, MJ O'Doherty, RM Saltiel, AR
Citation: Cb. Newgard et al., Organizing glucose disposal - Emerging roles of the glycogen targeting subunits of protein phosphatase-1, DIABETES, 49(12), 2000, pp. 1967-1977
Increased glucose disposal induced by adenovirus-mediated transfer of glucokinase to skeletal muscle in vivo
Authors: Jimenez-Chillaron, JC Newgard, CB Gomez-Foix, AM
Citation: Jc. Jimenez-chillaron et al., Increased glucose disposal induced by adenovirus-mediated transfer of glucokinase to skeletal muscle in vivo, FASEB J, 13(15), 1999, pp. 2153-2160
Metabolic engineering with recombinant adenoviruses
Authors: Antinozzi, PA Berman, HK O'Doherty, RM Newgard, CB
Citation: Pa. Antinozzi et al., Metabolic engineering with recombinant adenoviruses, ANN R NUTR, 19, 1999, pp. 511-544
Sparing effect of leptin on liver glycogen stores in rats during the fed-to-fasted transition
Authors: O'Doherty, RM Anderson, PR Zhao, AZ Bornfeldt, KE Newgard, CB
Citation: Rm. O'Doherty et al., Sparing effect of leptin on liver glycogen stores in rats during the fed-to-fasted transition, AM J P-ENDO, 40(3), 1999, pp. E544-E550
Reversing adipocyte differentiation: Implications for treatment of obesity
Authors: Zhou, YT Wang, ZW Higa, M Newgard, CB Unger, RH
Citation: Yt. Zhou et al., Reversing adipocyte differentiation: Implications for treatment of obesity, P NAS US, 96(5), 1999, pp. 2391-2395
Glucokinase overexpression restores glucose utilization and storage in cultured hepatocytes from male Zucker diabetic fatty rats
Authors: Seoane, J Barbera, A Telemaque-Potts, S Newgard, CB Guinovart, JJ
Citation: J. Seoane et al., Glucokinase overexpression restores glucose utilization and storage in cultured hepatocytes from male Zucker diabetic fatty rats, J BIOL CHEM, 274(45), 1999, pp. 31833-31838
Glucose-6-phosphatase overexpression lowers glucose 6-phosphate and inhibits glycogen synthesis and glycolysis in hepatocytes without affecting glucokinase translocation - Evidence against feedback inhibition of glucokinase
Authors: Aiston, S Trinh, KY Lange, AJ Newgard, CB Agius, L
Citation: S. Aiston et al., Glucose-6-phosphatase overexpression lowers glucose 6-phosphate and inhibits glycogen synthesis and glycolysis in hepatocytes without affecting glucokinase translocation - Evidence against feedback inhibition of glucokinase, J BIOL CHEM, 274(35), 1999, pp. 24559-24566
Increase in PDX-1 levels suppresses insulin gene expression in RIN 1046-38cells
Authors: Seijffers, R Ben-David, O Cohen, Y Karasik, A Berezin, M Newgard, CB Ferber, S
Citation: R. Seijffers et al., Increase in PDX-1 levels suppresses insulin gene expression in RIN 1046-38cells, ENDOCRINOL, 140(7), 1999, pp. 3311-3317
Adenovirus-mediated overexpression of uncoupling protein-2 in pancreatic islets of Zucker diabetic rats increases oxidative activity and improves beta-cell function
Authors: Wang, MY Shimabukuro, M Lee, Y Trinh, KY Chen, JL Newgard, CB Unger, RH
Citation: My. Wang et al., Adenovirus-mediated overexpression of uncoupling protein-2 in pancreatic islets of Zucker diabetic rats increases oxidative activity and improves beta-cell function, DIABETES, 48(5), 1999, pp. 1020-1025
Overexpression of G(11 alpha) and isoforms of phospholipase C in islet beta-cells reveals a lack of correlation between inositol phosphate accumulation and insulin secretion
Authors: Gasa, R Trinh, KY Yu, K Wilkie, TM Newgard, CB
Citation: R. Gasa et al., Overexpression of G(11 alpha) and isoforms of phospholipase C in islet beta-cells reveals a lack of correlation between inositol phosphate accumulation and insulin secretion, DIABETES, 48(5), 1999, pp. 1035-1044
Metabolic impact of glucokinase overexpression in liver - Lowering of blood glucose in fed rats is accompanied by hyperlipidemia
Authors: O'Doherty, RM Lehman, DL Telemaque-Potts, S Newgard, CB
Citation: Rm. O'Doherty et al., Metabolic impact of glucokinase overexpression in liver - Lowering of blood glucose in fed rats is accompanied by hyperlipidemia, DIABETES, 48(10), 1999, pp. 2022-2027
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