Authors:
Mulder, H
Lu, DH
Finley, J
An, J
Cohen, J
Antinozzi, PA
McGarry, JD
Newgard, CB
Citation: H. Mulder et al., Overexpression of a modified human malonyl-CoA decarboxylase blocks the glucose-induced increase in malonyl-CoA level but has no impact on insulin secretion in INS-1-derived (832/13) beta-cells, J BIOL CHEM, 276(9), 2001, pp. 6479-6484
Citation: J. An et al., Overexpression of the P46 (T1) translocase component of the glucose-6-phosphatase complex in hepatocytes impairs glycogen accumulation via hydrolysisof glucose 1-phosphate, J BIOL CHEM, 276(14), 2001, pp. 10722-10729
Citation: Gx. Chen et al., Expression of the transcription factor STAT-1 alpha in insulinoma cells protects against cytotoxic effects of multiple cytokines, J BIOL CHEM, 276(1), 2001, pp. 766-772
Authors:
Buettner, R
Newgard, CB
Rhodes, CJ
O'Doherty, RM
Citation: R. Buettner et al., Correction of diet-induced hyperglycemia, hyperinsulinemia, and skeletal muscle insulin resistance by moderate hyperleptinemia, AM J P-ENDO, 278(3), 2000, pp. E563-E569
Authors:
O'Doherty, RM
Jensen, PB
Anderson, P
Jones, JG
Berman, HK
Kearney, D
Newgard, CB
Citation: Rm. O'Doherty et al., Activation of direct and indirect pathways of glycogen synthesis by hepatic overexpression of protein targeting to glycogen, J CLIN INV, 105(4), 2000, pp. 479-488
Authors:
Bandyopadhyay, G
Sajan, MP
Kanoh, Y
Standaert, ML
Burke, TR
Quon, MJ
Reed, BC
Dikic, I
Noel, LE
Newgard, CB
Farese, R
Citation: G. Bandyopadhyay et al., Glucose activates mitogen-activated protein kinase (extracellular signal-regulated kinase) through proline-rich tyrosine kinase-2 and the glut1 glucose transporter, J BIOL CHEM, 275(52), 2000, pp. 40817-40826
Authors:
Lerin, C
Montell, E
Berman, HK
Newgard, CB
Gomez-Foix, AM
Citation: C. Lerin et al., Overexpression of protein targeting to glycogen in cultured human muscle cells stimulates glycogen synthesis independent of glycogen and glucose 6-phosphate levels, J BIOL CHEM, 275(51), 2000, pp. 39991-39995
Authors:
Roduit, R
Morin, J
Masse, F
Segall, L
Roche, E
Newgard, CB
Assimacopoulos-Jeannet, F
Prentki, M
Citation: R. Roduit et al., Glucose down-regulates the expression of the peroxisome proliferator-activated receptor-alpha gene in the pancreatic beta-cell, J BIOL CHEM, 275(46), 2000, pp. 35799-35806
Authors:
Gasa, R
Jensen, PB
Berman, HK
Brady, MJ
DePaoli-Roach, AA
Newgard, CB
Citation: R. Gasa et al., Distinctive regulatory and metabolic properties of glycogen-targeting subunits of protein phosphatase-1 (PTG, G(L), G(M)/R-G1) expressed in hepatocytes, J BIOL CHEM, 275(34), 2000, pp. 26396-26403
Authors:
Chen, GX
Hohmeier, HE
Gasa, R
Tran, VV
Newgard, CB
Citation: Gx. Chen et al., Selection of insulinoma cell lines with resistance to interleukin-1 beta- and gamma-interferon-induced cytotoxicity, DIABETES, 49(4), 2000, pp. 562-570
Authors:
Hohmeier, HE
Mulder, H
Chen, GX
Henkel-Rieger, R
Prentki, M
Newgard, CB
Citation: He. Hohmeier et al., Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and -independent glucose-stimulated insulin secretion, DIABETES, 49(3), 2000, pp. 424-430
Authors:
Newgard, CB
Brady, MJ
O'Doherty, RM
Saltiel, AR
Citation: Cb. Newgard et al., Organizing glucose disposal - Emerging roles of the glycogen targeting subunits of protein phosphatase-1, DIABETES, 49(12), 2000, pp. 1967-1977
Authors:
Jimenez-Chillaron, JC
Newgard, CB
Gomez-Foix, AM
Citation: Jc. Jimenez-chillaron et al., Increased glucose disposal induced by adenovirus-mediated transfer of glucokinase to skeletal muscle in vivo, FASEB J, 13(15), 1999, pp. 2153-2160
Authors:
O'Doherty, RM
Anderson, PR
Zhao, AZ
Bornfeldt, KE
Newgard, CB
Citation: Rm. O'Doherty et al., Sparing effect of leptin on liver glycogen stores in rats during the fed-to-fasted transition, AM J P-ENDO, 40(3), 1999, pp. E544-E550
Authors:
Seoane, J
Barbera, A
Telemaque-Potts, S
Newgard, CB
Guinovart, JJ
Citation: J. Seoane et al., Glucokinase overexpression restores glucose utilization and storage in cultured hepatocytes from male Zucker diabetic fatty rats, J BIOL CHEM, 274(45), 1999, pp. 31833-31838
Authors:
Aiston, S
Trinh, KY
Lange, AJ
Newgard, CB
Agius, L
Citation: S. Aiston et al., Glucose-6-phosphatase overexpression lowers glucose 6-phosphate and inhibits glycogen synthesis and glycolysis in hepatocytes without affecting glucokinase translocation - Evidence against feedback inhibition of glucokinase, J BIOL CHEM, 274(35), 1999, pp. 24559-24566
Authors:
Seijffers, R
Ben-David, O
Cohen, Y
Karasik, A
Berezin, M
Newgard, CB
Ferber, S
Citation: R. Seijffers et al., Increase in PDX-1 levels suppresses insulin gene expression in RIN 1046-38cells, ENDOCRINOL, 140(7), 1999, pp. 3311-3317
Authors:
Wang, MY
Shimabukuro, M
Lee, Y
Trinh, KY
Chen, JL
Newgard, CB
Unger, RH
Citation: My. Wang et al., Adenovirus-mediated overexpression of uncoupling protein-2 in pancreatic islets of Zucker diabetic rats increases oxidative activity and improves beta-cell function, DIABETES, 48(5), 1999, pp. 1020-1025
Authors:
Gasa, R
Trinh, KY
Yu, K
Wilkie, TM
Newgard, CB
Citation: R. Gasa et al., Overexpression of G(11 alpha) and isoforms of phospholipase C in islet beta-cells reveals a lack of correlation between inositol phosphate accumulation and insulin secretion, DIABETES, 48(5), 1999, pp. 1035-1044
Authors:
O'Doherty, RM
Lehman, DL
Telemaque-Potts, S
Newgard, CB
Citation: Rm. O'Doherty et al., Metabolic impact of glucokinase overexpression in liver - Lowering of blood glucose in fed rats is accompanied by hyperlipidemia, DIABETES, 48(10), 1999, pp. 2022-2027