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Results:
1-12
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Results: 12
Authors:
Bateman, KP
Castonguay, G
Xu, LJ
Rowland, S
Nicoll-Griffith, DA
Kelly, N
Chan, CC
Citation: Kp. Bateman et al., Reduction of animal usage by serial bleeding of mice for pharmacokinetic studies: application of robotic sample preparation and fast liquid chromatography-mass spectrometry, J CHROMAT B, 754(1), 2001, pp. 245-251
Authors:
Chauret, N
Yergey, JA
Brideau, C
Friesen, RW
Mancini, J
Riendeau, D
Silva, J
Styhler, A
Trimble, LA
Nicoll-Griffith, DA
Citation: N. Chauret et al., In vitro metabolism considerations, including activity testing of metabolites, in the discovery and selection of the COX-2 inhibitor etoricoxib (MK-0663), BIOORG MED, 11(8), 2001, pp. 1059-1062
Authors:
Chauret, N
Dobbs, B
Lackman, RL
Bateman, K
Nicoll-Griffith, DA
Stresser, DM
Ackermann, JM
Turner, SD
Miller, VP
Crespi, CL
Citation: N. Chauret et al., The use of 3-[2-(N,N-diethyl-N-methylammonium)ethyl]-7-methoxy-4-methylcoumarin (AMMC) as a specific CYP2D6 probe in human liver microsomes, DRUG META D, 29(9), 2001, pp. 1196-1200
In vitro metabolism of the Cox-2 inhibitor DFU, including a novel glutathione adduct rearomatization
Authors:
Yergey, JA
Trimble, LA
Silva, J
Chauret, N
Li, C
Therien, M
Grimm, E
Nicoll-Griffith, DA
Citation: Ja. Yergey et al., In vitro metabolism of the Cox-2 inhibitor DFU, including a novel glutathione adduct rearomatization, DRUG META D, 29(5), 2001, pp. 638-644
Authors:
Li, C
Chauret, N
Trimble, LA
Nicoll-Griffith, DA
Silva, JM
Macdonald, D
Perrier, H
Yergey, JA
Parton, T
Alexander, RP
Warrellow, GJ
Citation: C. Li et al., Investigation of the in vitro metabolism profile of a phosphodiesterase-IVinhibitor, CDP-840: Leading to structural optimization, DRUG META D, 29(3), 2001, pp. 232-241
Authors:
Nicoll-Griffith, DA
Silva, JM
Chauret, N
Day, S
Leblanc, Y
Roy, P
Yergey, JA
Dixit, R
Patrick, D
Citation: Da. Nicoll-griffith et al., Application of rat hepatocyte culture to predict in vivo metabolic auto-induction: Studies with DFP, a cyclooxygenase-2 inhibitor, DRUG META D, 29(2), 2001, pp. 159-165
Authors:
Hult, M
Nobel, CSI
Abrahmsen, L
Nicoll-Griffith, DA
Jornvall, H
Oppermann, UCT
Citation: M. Hult et al., Novel enzymological profiles of human 11 beta-hydroxysteroid dehydrogenasetype 1, CHEM-BIO IN, 130(1-3), 2001, pp. 805-814
Authors:
Nicoll-Griffith, DA
Yergey, JA
Trimble, LA
Silva, JM
Li, C
Chauret, N
Gauthier, JY
Grimm, E
Leger, S
Roy, P
Therien, M
Wang, ZY
Prasit, P
Zamboni, R
Young, RN
Brideau, C
Chan, CC
Mancini, J
Riendeau, D
Citation: Da. Nicoll-griffith et al., Synthesis, characterization, and activity of metabolites derived from the cyclooxygenase-2 inhibitor rofecoxib (MK-0966, Vioxx (TM)), BIOORG MED, 10(23), 2000, pp. 2683-2686
Authors:
Nicoll-Griffith, DA
Falgueyret, JP
Silva, JM
Morin, PE
Trimble, L
Chan, CC
Clas, S
Leger, S
Wang, ZY
Yergey, JA
Riendeau, D
Citation: Da. Nicoll-griffith et al., Oxidative bioactivation of the lactol prodrug of a lactone cyclooxygenase-2 inhibitor, DRUG META D, 27(3), 1999, pp. 403-409
Authors:
Day, SH
Nicoll-Griffith, DA
Silva, JM
Citation: Sh. Day et al., Cryopreservation of rat and human liver slices by rapid freezing, CRYOBIOLOGY, 38(2), 1999, pp. 154-159
Authors:
Silva, JM
Day, SH
Nicoll-Griffith, DA
Citation: Jm. Silva et al., Induction of cytochrome-P450 in cryopreserved rat and human hepatocytes, CHEM-BIO IN, 121(1), 1999, pp. 49-63
Authors:
Chauret, N
Tremblay, N
Lackman, RL
Gauthier, JY
Silva, JM
Marois, J
Yergey, JA
Nicoll-Griffith, DA
Citation: N. Chauret et al., Description of a 96-well plate assay to measure cytochrome P4503A inhibition in human liver microsomes using a selective fluorescent probe, ANALYT BIOC, 276(2), 1999, pp. 215-226
Risultati:
1-12
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