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Results: 1-6 |
Results: 6
6-Substituted-4-(3-bromophenylamino)quinazolines as putative irreversible inhibitors of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor (HER-2) tyrosine kinases with enhanced antitumor activity
Authors: Tsou, HR Mamuya, N Johnson, BD Reich, MF Gruber, BC Ye, F Nilakantan, R Shen, R Discafani, C DeBlanc, R Davis, R Koehn, FE Greenberger, LM Wang, YF Wissner, A
Citation: Hr. Tsou et al., 6-Substituted-4-(3-bromophenylamino)quinazolines as putative irreversible inhibitors of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor (HER-2) tyrosine kinases with enhanced antitumor activity, J MED CHEM, 44(17), 2001, pp. 2719-2734
Molecular modeling of the aldose reductase-inhibitor complex based on the X-ray crystal structure and studies with single-site-directed mutants
Authors: Singh, SB Malamas, MS Hohman, TC Nilakantan, R Carper, DA Kitchen, D
Citation: Sb. Singh et al., Molecular modeling of the aldose reductase-inhibitor complex based on the X-ray crystal structure and studies with single-site-directed mutants, J MED CHEM, 43(6), 2000, pp. 1062-1070
4-Anilino-6,7-dialkoxyquinolime-3-carbonitrile inhibitors of epidermal growth factor receptor kinase and their bioisosteric relationship to the 4-anilino-6,7-dialkoxyquinazoline inhibitors
Authors: Wissner, A Berger, DM Boschelli, DH Floyd, MB Greenberger, LM Gruber, BC Johnson, BD Mamuya, N Nilakantan, R Reich, MF Shen, R Tsou, HR Upeslacis, E Wang, YF Wu, BQ Ye, F Zhang, N
Citation: A. Wissner et al., 4-Anilino-6,7-dialkoxyquinolime-3-carbonitrile inhibitors of epidermal growth factor receptor kinase and their bioisosteric relationship to the 4-anilino-6,7-dialkoxyquinazoline inhibitors, J MED CHEM, 43(17), 2000, pp. 3244-3256
Structure-based design of a novel, potent, and selective inhibitor for MMP-13 utilizing NMR spectroscopy and computer-aided molecular design
Authors: Chen, JM Nelson, FC Levin, JI Mobilio, D Moy, FJ Nilakantan, R Zask, A Powers, R
Citation: Jm. Chen et al., Structure-based design of a novel, potent, and selective inhibitor for MMP-13 utilizing NMR spectroscopy and computer-aided molecular design, J AM CHEM S, 122(40), 2000, pp. 9648-9654
Inhibition of influenza A virus replication by compounds interfering with the fusogenic function of the viral hemagglutinin
Authors: Plotch, SJ O'Hara, B Morin, J Palant, O LaRocque, J Bloom, JD Lang, SA DiGrandi, MJ Bradley, M Nilakantan, R Gluzman, Y
Citation: Sj. Plotch et al., Inhibition of influenza A virus replication by compounds interfering with the fusogenic function of the viral hemagglutinin, J VIROLOGY, 73(1), 1999, pp. 140-151
Irreversible inhibition of epidermal growth factor receptor tyrosine kinase with in vivo activity by N-[4-[(3-bromophenyl)amino]-6-quinazolinyl]-2-butynamide (CL-387,785)
Authors: Discafani, CM Carroll, ML Floyd, MB Hollander, IJ Husain, Z Johnson, BD Kitchen, D May, MK Malo, MS Minnick, AA Nilakantan, R Shen, R Wang, YF Wissner, A Greenberger, LM
Citation: Cm. Discafani et al., Irreversible inhibition of epidermal growth factor receptor tyrosine kinase with in vivo activity by N-[4-[(3-bromophenyl)amino]-6-quinazolinyl]-2-butynamide (CL-387,785), BIOCH PHARM, 57(8), 1999, pp. 917-925
Risultati: 1-6 |