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Results: 1-10 |
Results: 10
O[2,3-C]PYRIDIN-5-YL-ETHYL)THIO]-4-PYRIMIDINAMINE, PNU-142721, A NEW BROAD-SPECTRUM HIV-1 NONNUCLEOSIDE REVERSE-TRANSCRIPTASE INHIBITOR
Authors: WISHKA DG GRABER DR KOPTA LA OLMSTED RA FRIIS JM HOSLEY JD ADAMS WJ SEEST EP CASTLE TM DOLAK LA KEISER BJ YAGI Y JEGANATHAN A SCHLACHTER ST MURPHY MJ CLEEK GJ NUGENT RA POPPE SM SWANEY SM HAN FS WATT W WHITE WL POEL TJ THOMAS RC VOORMAN RL STEFANSKI KJ STEHLE RG TARPLEY WG MORRIS J
Citation: Dg. Wishka et al., O[2,3-C]PYRIDIN-5-YL-ETHYL)THIO]-4-PYRIMIDINAMINE, PNU-142721, A NEW BROAD-SPECTRUM HIV-1 NONNUCLEOSIDE REVERSE-TRANSCRIPTASE INHIBITOR, Journal of medicinal chemistry, 41(9), 1998, pp. 1357-1360
PYRIMIDINE THIOETHERS - A NOVEL CLASS OF HIV-1 REVERSE-TRANSCRIPTASE INHIBITORS WITH ACTIVITY AGAINST BHAP-RESISTANT HIV
Authors: NUGENT RA SCHLACHTER ST MURPHY MJ CLEEK GJ POEL TJ WISHKA DG GRABER DR YAGI Y KEISER BJ OLMSTED RA KOPTA LA SWANEY SM POPPE SM MORRIS J TARPLEY WG THOMAS RC
Citation: Ra. Nugent et al., PYRIMIDINE THIOETHERS - A NOVEL CLASS OF HIV-1 REVERSE-TRANSCRIPTASE INHIBITORS WITH ACTIVITY AGAINST BHAP-RESISTANT HIV, Journal of medicinal chemistry, 41(20), 1998, pp. 3793-3803
(ALKYLAMINO)PIPERIDINE BIS(HETEROARYL)PIPERIZINE ANALOGS ARE POTENT, BROAD-SPECTRUM NONNUCLEOSIDE REVERSE-TRANSCRIPTASE INHIBITORS OF DRUG-RESISTANT ISOLATES OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 (HIV-1) AND SELECT FOR DRUG-RESISTANT VARIANTS OF HIV-1(IIIB) WITH REDUCED REPLICATION PHENOTYPES
Authors: OLMSTED RA SLADE DE KOPTA LA POPPE SM POEL TJ NEWPORT SW RANK KB BILES C MORGE RA DUEWEKE TJ YAGI Y ROMERO DL THOMAS RC SHARMA SK TARPLEY WG
Citation: Ra. Olmsted et al., (ALKYLAMINO)PIPERIDINE BIS(HETEROARYL)PIPERIZINE ANALOGS ARE POTENT, BROAD-SPECTRUM NONNUCLEOSIDE REVERSE-TRANSCRIPTASE INHIBITORS OF DRUG-RESISTANT ISOLATES OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 (HIV-1) AND SELECT FOR DRUG-RESISTANT VARIANTS OF HIV-1(IIIB) WITH REDUCED REPLICATION PHENOTYPES, Journal of virology, 70(6), 1996, pp. 3698-3705
SYNTHESIS AND BIOACTIVITY OF NOVEL BIS (HETEROARYL)PIPERAZINE (BHAP) REVERSE-TRANSCRIPTASE INHIBITORS - STRUCTURE-ACTIVITY-RELATIONSHIPS AND INCREASED METABOLIC STABILITY OF NOVEL SUBSTITUTED PYRIDINE ANALOGS
Authors: GENIN MJ POEL TJ YAGI Y BILES C ALTHAUS I KEISER BJ KOPTA LA FRIIS JM REUSSER F ADAMS WJ OLMSTED RA VOORMAN RL THOMAS RC ROMERO DL
Citation: Mj. Genin et al., SYNTHESIS AND BIOACTIVITY OF NOVEL BIS (HETEROARYL)PIPERAZINE (BHAP) REVERSE-TRANSCRIPTASE INHIBITORS - STRUCTURE-ACTIVITY-RELATIONSHIPS AND INCREASED METABOLIC STABILITY OF NOVEL SUBSTITUTED PYRIDINE ANALOGS, Journal of medicinal chemistry, 39(26), 1996, pp. 5267-5275
TARGETING DELAVIRDINE ATEVIRDINE RESISTANT HIV-1 - IDENTIFICATION OF (ALKYLAMINO)PIPERIDINE-CONTAINING BIS(HETEROARYL)PIPERAZINES AS BROAD-SPECTRUM HIV-1 REVERSE-TRANSCRIPTASE INHIBITORS/
Authors: ROMERO DL OLMSTED RA POEL TJ MORGE RA BILES C KEISER BJ KOPTA LA FRIIS JM HOSLEY JD STEFANSKI KJ WISHKA DG EVANS DB MORRIS J STEHLE RG SHARMA SK YAGI Y VOORMAN RL ADAMS WJ TARPLEY WG THOMAS RC
Citation: Dl. Romero et al., TARGETING DELAVIRDINE ATEVIRDINE RESISTANT HIV-1 - IDENTIFICATION OF (ALKYLAMINO)PIPERIDINE-CONTAINING BIS(HETEROARYL)PIPERAZINES AS BROAD-SPECTRUM HIV-1 REVERSE-TRANSCRIPTASE INHIBITORS/, Journal of medicinal chemistry, 39(19), 1996, pp. 3769-3789
A DRUG-RESISTANCE MUTATION IN THE INHIBITOR BINDING POCKET OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 REVERSE-TRANSCRIPTASE IMPAIRS DNA-SYNTHESIS AND RNA DEGRADATION
Authors: FAN NS RANK KB SLADE DE POPPE SM EVANS DB KOPTA LA OLMSTED RA THOMAS RC TARPLEY WG SHARMA SK
Citation: Ns. Fan et al., A DRUG-RESISTANCE MUTATION IN THE INHIBITOR BINDING POCKET OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 REVERSE-TRANSCRIPTASE IMPAIRS DNA-SYNTHESIS AND RNA DEGRADATION, Biochemistry, 35(30), 1996, pp. 9737-9745
A DRUG-RESISTANCE MUTATION (G190E) IN THE INHIBITOR BINDING POCKET IMPAIRS BOTH RNA-DEPENDENT DNA-POLYMERASE AND RIBONUCLEASE-H ACTIVITIES OF HIV-1 REVERSE-TRANSCRIPTASE
Authors: SHARMA SK FAN N RANK KB KOPTA LA OLMSTED RA POPPE SM SLADE DE THOMAS RC TARPLEY WG
Citation: Sk. Sharma et al., A DRUG-RESISTANCE MUTATION (G190E) IN THE INHIBITOR BINDING POCKET IMPAIRS BOTH RNA-DEPENDENT DNA-POLYMERASE AND RIBONUCLEASE-H ACTIVITIES OF HIV-1 REVERSE-TRANSCRIPTASE, Journal of acquired immune deficiency syndromes and human retrovirology, 10, 1995, pp. 2-2
NUCLEOTIDE-SEQUENCE ANALYSIS OF PUMA LENTIVIRUS (PLV-14) - GENOMIC ORGANIZATION AND RELATIONSHIP TO OTHER LENTIVIRUSES
Authors: LANGLEY RJ HIRSCH VM OBRIEN SJ ADGERJOHNSON D GOEKEN RM OLMSTED RA
Citation: Rj. Langley et al., NUCLEOTIDE-SEQUENCE ANALYSIS OF PUMA LENTIVIRUS (PLV-14) - GENOMIC ORGANIZATION AND RELATIONSHIP TO OTHER LENTIVIRUSES, Virology, 202(2), 1994, pp. 853-864
NEUROLOGICAL ABNORMALITIES ASSOCIATED WITH FELINE IMMUNODEFICIENCY VIRUS-INFECTION
Authors: PHILLIPS TR PROSPEROGARCIA O PUAOI DL LERNER DL FOX HS OLMSTED RA BLOOM FE HENRIKSEN SJ ELDER JH
Citation: Tr. Phillips et al., NEUROLOGICAL ABNORMALITIES ASSOCIATED WITH FELINE IMMUNODEFICIENCY VIRUS-INFECTION, Journal of General Virology, 75, 1994, pp. 979-987
DEVELOPMENT OF A NOVEL SUBUNIT VACCINE THAT PROTECTS COTTON RATS AGAINST BOTH HUMAN RESPIRATORY SYNCYTIAL VIRUS AND HUMAN PARAINFLUENZA VIRUS TYPE-3
Authors: HOMA FL BRIDEAU RJ LEHMAN DJ THOMSEN DR OLMSTED RA WATHEN MW
Citation: Fl. Homa et al., DEVELOPMENT OF A NOVEL SUBUNIT VACCINE THAT PROTECTS COTTON RATS AGAINST BOTH HUMAN RESPIRATORY SYNCYTIAL VIRUS AND HUMAN PARAINFLUENZA VIRUS TYPE-3, Journal of General Virology, 74, 1993, pp. 1995-1999
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