Authors:
Fevig, JM
Pinto, DJ
Han, Q
Quan, ML
Pruitt, JR
Jacobson, IC
Galemmo, RA
Wang, SA
Orwat, MJ
Bostrom, LL
Knabb, RM
Wong, PC
Lam, PYS
Wexler, RR
Citation: Jm. Fevig et al., Synthesis and SAR of benzamidine factor Xa inhibitors containing a vicinally-substituted heterocyclic core, BIOORG MED, 11(5), 2001, pp. 641-645
Authors:
Pinto, DJP
Orwat, MJ
Wang, SG
Fevig, JM
Quan, ML
Amparo, E
Cacciola, J
Rossi, KA
Alexander, RS
Smallwood, AM
Luettgen, JM
Liang, L
Aungst, BJ
Wright, MR
Knabb, RM
Wong, PC
Wexler, RR
Lam, PYS
Citation: Djp. Pinto et al., Discovery of 1-[3-(aminomethyl)phenyl]-N-[3-fluoro-2 '- (methylsulfonyl)-[1,1 '-biphenyl]-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide (DPC423), a highly potent, selective, and orally bioavailable inhibitor of blood coagulation factor Xa, J MED CHEM, 44(4), 2001, pp. 566-578
Authors:
Pinto, DJP
Batt, DG
Pitts, WJ
Petraitis, JJ
Orwat, MJ
Wang, SG
Jetter, JW
Sherk, SR
Houghton, GC
Copeland, RA
Covington, MB
Trzaskos, JM
Magolda, RL
Citation: Djp. Pinto et al., Terphenyl cyclooxygenase-2 (COX-2) inhibitors: Optimization of the centralring and o-biphenyl analogs, BIOORG MED, 9(7), 1999, pp. 919-924
Authors:
Olson, RE
Sielecki, TM
Wityak, J
Pinto, DJ
Batt, DG
Frietze, WE
Liu, J
Tobin, AE
Orwat, MJ
Di Meo, SV
Houghton, GC
Lalka, GK
Mousa, SA
Racanelli, AL
Hausner, EA
Kapil, RP
Rabel, HR
Thoolen, MJ
Reilly, TM
Anderson, PS
Wexler, RR
Citation: Re. Olson et al., Orally active isoxazoline glycoprotein IIb/IIIa antagonists with extended duration of action, J MED CHEM, 42(7), 1999, pp. 1178-1192