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Results: 1-25 | 26-42
Results: 1-25/42
High-performance liquid chromatography with chemiluminescence detection ofpenbutolol and its hydroxylated metabolite in rat plasma
Authors: Funato, K Imai, T Nakashima, K Otagiri, M
Citation: K. Funato et al., High-performance liquid chromatography with chemiluminescence detection ofpenbutolol and its hydroxylated metabolite in rat plasma, J CHROMAT B, 757(2), 2001, pp. 229-235
Stability of a cisplatin-chondroitin sulfate A complex in plasma and kidney in terms of protein binding
Authors: Zhang, JS Ma, SF Suenaga, A Otagiri, M
Citation: Js. Zhang et al., Stability of a cisplatin-chondroitin sulfate A complex in plasma and kidney in terms of protein binding, BIOL PHAR B, 24(8), 2001, pp. 970-972
Purification and characterization of L-2,3-butanediol dehydrogenase of Brevibacterium saccharolyticum C-1012 expressed in Escherichia coli
Authors: Takusagawa, Y Otagiri, M Ui, S Ohtsuki, T Mimura, A Ohkuma, M Kudo, T
Citation: Y. Takusagawa et al., Purification and characterization of L-2,3-butanediol dehydrogenase of Brevibacterium saccharolyticum C-1012 expressed in Escherichia coli, BIOS BIOT B, 65(8), 2001, pp. 1876-1878
Crystallization and preliminary X-ray studies of meso-2,3-butanediol dehydrogenase from Klebsiella pneumoniae IAM1063
Authors: Otagiri, M Kurisu, G Swaminathan, S Ui, S Yoneda, S Ohkuma, M Kudo, T Kusunoki, M
Citation: M. Otagiri et al., Crystallization and preliminary X-ray studies of meso-2,3-butanediol dehydrogenase from Klebsiella pneumoniae IAM1063, ACT CRYST D, 57, 2001, pp. 857-859
Effect of oxidative stress on the structure and function of human serum albumin
Authors: Anraku, M Yamasaki, K Maruyama, T Kragh-Hansen, U Otagiri, M
Citation: M. Anraku et al., Effect of oxidative stress on the structure and function of human serum albumin, PHARM RES, 18(5), 2001, pp. 632-639
Interaction mechanism between indoxyl sulfate, a typical uremic toxin bound to site II, and ligands bound to site I of human serum albumin
Authors: Sakai, T Yamasaki, K Sako, T Kragh-Hansen, U Suenaga, A Otagiri, M
Citation: T. Sakai et al., Interaction mechanism between indoxyl sulfate, a typical uremic toxin bound to site II, and ligands bound to site I of human serum albumin, PHARM RES, 18(4), 2001, pp. 520-524
Conformational stability and warfarin-binding properties of human serum albumin studied by recombinant mutants
Authors: Watanabe, H Kragh-Hansen, U Tanase, S Nakajou, K Mitarai, M Iwao, Y Maruyama, T Otagiri, M
Citation: H. Watanabe et al., Conformational stability and warfarin-binding properties of human serum albumin studied by recombinant mutants, BIOCHEM J, 357, 2001, pp. 269-274
Flunitrazepam, a 7-nitro-1,4-benzodiazepine that is unable to bind to the indole-benzodiazepine site of human serum albumin
Authors: Chuang, VTG Otagiri, M
Citation: Vtg. Chuang et M. Otagiri, Flunitrazepam, a 7-nitro-1,4-benzodiazepine that is unable to bind to the indole-benzodiazepine site of human serum albumin, BBA-PROT ST, 1546(2), 2001, pp. 337-345
Strain-, sex- and species-related differences of acetohexamide reductase and 20 beta-hydroxysteroid dehydrogenase activities in liver microsomes of experimental animals
Authors: Imamura, Y Uchida, A Takada, H Otagiri, M Tsuchiya, K
Citation: Y. Imamura et al., Strain-, sex- and species-related differences of acetohexamide reductase and 20 beta-hydroxysteroid dehydrogenase activities in liver microsomes of experimental animals, YAKUGAKU ZA, 121(1), 2001, pp. 85-91
Crystal structure of meso-2,3-butanediol dehydrogenase in a complex with NAD(+) and inhibitor mercaptoethanol at 1.7 angstrom resolution for understanding of chiral substrate recognition mechanisms
Authors: Otagiri, M Kurisu, G Ui, S Takusagawa, Y Ohkuma, M Kudo, T Kusunoki, M
Citation: M. Otagiri et al., Crystal structure of meso-2,3-butanediol dehydrogenase in a complex with NAD(+) and inhibitor mercaptoethanol at 1.7 angstrom resolution for understanding of chiral substrate recognition mechanisms, J BIOCHEM, 129(2), 2001, pp. 205-208
FK506 (tacrolimus) increases rat alpha(1)-acid glycoprotein expression in liver and primary cultured hepatocytes
Authors: Shimoishi, K Kai, H Kabu, K Komori, T Maruyama, T Otagiri, M
Citation: K. Shimoishi et al., FK506 (tacrolimus) increases rat alpha(1)-acid glycoprotein expression in liver and primary cultured hepatocytes, EUR J PHARM, 420(2-3), 2001, pp. 91-95
Up-regulation by clarithromycin of alpha(1)-acid glycoprotein expression in liver and primary cultured hepatocytes
Authors: Komori, T Kai, H Shimoishi, K Kabu, K Nonaka, A Maruyama, T Tamura, K Otagiri, M
Citation: T. Komori et al., Up-regulation by clarithromycin of alpha(1)-acid glycoprotein expression in liver and primary cultured hepatocytes, BIOCH PHARM, 62(10), 2001, pp. 1391-1397
Determination of reduced, protein-unbound, and total concentrations of N-acetyl-L-cysteine and L-cysteine in rat plasma by postcolumn ligand substitution high-performance liquid chromatography
Authors: Harada, D Naito, S Kawauchi, Y Ishikawa, K Koshitani, O Hiraoka, I Otagiri, M
Citation: D. Harada et al., Determination of reduced, protein-unbound, and total concentrations of N-acetyl-L-cysteine and L-cysteine in rat plasma by postcolumn ligand substitution high-performance liquid chromatography, ANALYT BIOC, 290(2), 2001, pp. 251-259
Biological properties of low molecular fragmented gelatine and its evaluation as a rapid absorptive additive in human volunteers
Authors: Imai, T Kimura, S Otagiri, M
Citation: T. Imai et al., Biological properties of low molecular fragmented gelatine and its evaluation as a rapid absorptive additive in human volunteers, STP PHARM S, 10(4), 2000, pp. 321-326
A strategy for the immediate-release of indomethacin from a sustained-release preparation using a chitosan hydrolysate
Authors: Imai, T Shiraishi, S Otagiri, M
Citation: T. Imai et al., A strategy for the immediate-release of indomethacin from a sustained-release preparation using a chitosan hydrolysate, STP PHARM S, 10(1), 2000, pp. 57-62
Characterization of a binding site of UCN-01, a novel anticancer drug on alpha(1)-acid glycoprotein
Authors: Kurata, N Matsushita, S Nishi, K Watanabe, H Kobayashi, S Suenaga, A Otagiri, M
Citation: N. Kurata et al., Characterization of a binding site of UCN-01, a novel anticancer drug on alpha(1)-acid glycoprotein, BIOL PHAR B, 23(7), 2000, pp. 893-895
Catalytic properties for naphthoquinones and partial primary structure of rabbit heart acetohexamide reductase
Authors: Imamura, Y Koga, T Uriu, Y Otagiri, M Satoh, K Hara, A
Citation: Y. Imamura et al., Catalytic properties for naphthoquinones and partial primary structure of rabbit heart acetohexamide reductase, BIOL PHAR B, 23(2), 2000, pp. 155-158
Effects of a cisplatin-chondroitin sulfate A complex in reducing the nephrotoxicity of cisplatin
Authors: Zhang, JS Imai, T Otagiri, M
Citation: Js. Zhang et al., Effects of a cisplatin-chondroitin sulfate A complex in reducing the nephrotoxicity of cisplatin, ARCH TOXIC, 74(6), 2000, pp. 300-307
Role of Arg-410 and Tyr-411 in human serum albumin for ligand binding and esterase-like activity
Authors: Watanabe, H Tanase, S Nakajou, K Maruyama, T Kragh-Hansen, U Otagiri, M
Citation: H. Watanabe et al., Role of Arg-410 and Tyr-411 in human serum albumin for ligand binding and esterase-like activity, BIOCHEM J, 349, 2000, pp. 813-819
Comparison of the pharmaceutical properties of sustained-release gel beadsprepared by alginate having different molecular size with commercial sustained-release tablet
Authors: Imai, T Kawasaki, C Nishiyama, T Otagiri, M
Citation: T. Imai et al., Comparison of the pharmaceutical properties of sustained-release gel beadsprepared by alginate having different molecular size with commercial sustained-release tablet, PHARMAZIE, 55(3), 2000, pp. 218-222
Decreased bilirubin-binding capacity in uremic serum caused by an accumulation of furan dicarboxylic acid
Authors: Tsutsumi, Y Maruyama, T Takadate, A Shimada, H Otagiri, M
Citation: Y. Tsutsumi et al., Decreased bilirubin-binding capacity in uremic serum caused by an accumulation of furan dicarboxylic acid, NEPHRON, 85(1), 2000, pp. 60-64
Further studies on 20 beta-hydroxysteroid dehydrogenase with carbonyl reductase-like activity present in liver microsomes of male rats
Authors: Takada, H Uchida, A Kamizono, R Otagiri, M Imamura, Y
Citation: H. Takada et al., Further studies on 20 beta-hydroxysteroid dehydrogenase with carbonyl reductase-like activity present in liver microsomes of male rats, LIFE SCI, 67(17), 2000, pp. 2075-2082
Inhibitory effects of flavonoids on rabbit heart carbonyl reductase
Authors: Imamura, Y Migita, T Uriu, Y Otagiri, M Okawara, T
Citation: Y. Imamura et al., Inhibitory effects of flavonoids on rabbit heart carbonyl reductase, J BIOCHEM, 127(4), 2000, pp. 653-658
Inclusion complex of 3,9-bis(N,N-dimethylcarbamoyloxy)-5H-benzofuro[3,2-c]quinoline-6-one (KCA-098) with heptakis(2,6-di-O-methyl)-beta-cyclodextrin:Interaction and dissolution properties
Authors: Yamada, T Imai, T Ouchi, K Otagiri, M Hirayama, F Uekama, K
Citation: T. Yamada et al., Inclusion complex of 3,9-bis(N,N-dimethylcarbamoyloxy)-5H-benzofuro[3,2-c]quinoline-6-one (KCA-098) with heptakis(2,6-di-O-methyl)-beta-cyclodextrin:Interaction and dissolution properties, CHEM PHARM, 48(9), 2000, pp. 1264-1269
Stereoselective serum protein binding of ketoprofen in liver diseases
Authors: Sakai, T Maruyama, T Sako, T Ahmed, S Zuidema, X Fujiyama, S Otagiri, M
Citation: T. Sakai et al., Stereoselective serum protein binding of ketoprofen in liver diseases, ENANTIOMER, 4(5), 1999, pp. 477-482
Risultati: 1-25 | 26-42