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Results: 1-19 |
Results: 19
THE PRECLINICAL PHARMACOLOGICAL PROFILE OF THE POTENT AND SELECTIVE LEUKOTRIENE B-4 ANTAGONIST CP-195543
Authors: SHOWELL HJ CONKLYN MJ ALPERT R HINGORANI GP WRIGHT KF SMITH MA STAM E SALTER ED SCAMPOLI DN MELTZER S REITER LA KOCH K PISCOPIO AD CORTINA SR LOPEZANAYA A PETTIPHER ER MILICI AJ GRIFFITHS RJ
Citation: Hj. Showell et al., THE PRECLINICAL PHARMACOLOGICAL PROFILE OF THE POTENT AND SELECTIVE LEUKOTRIENE B-4 ANTAGONIST CP-195543, The Journal of pharmacology and experimental therapeutics, 285(3), 1998, pp. 946-954
STRIKING EFFECT OF HYDROXAMIC ACID SUBSTITUTION ON THE PHOSPHODIESTERASE TYPE-4 (PDE4) AND TNF-ALPHA INHIBITORY ACTIVITY OF 2 SERIES OF ROLIPRAM ANALOGS - IMPLICATIONS FOR A NEW ACTIVE-SITE MODEL OF PDE4
Authors: KLEINMAN EF CAMPBELL E GIORDANO LA COHAN VL JENKINSON TH CHENG JB SHIRLEY JT PETTIPHER ER SALTER ED HIBBS TA DICAPUA FM BORDNER J
Citation: Ef. Kleinman et al., STRIKING EFFECT OF HYDROXAMIC ACID SUBSTITUTION ON THE PHOSPHODIESTERASE TYPE-4 (PDE4) AND TNF-ALPHA INHIBITORY ACTIVITY OF 2 SERIES OF ROLIPRAM ANALOGS - IMPLICATIONS FOR A NEW ACTIVE-SITE MODEL OF PDE4, Journal of medicinal chemistry, 41(3), 1998, pp. 266-270
THE INHIBITORY EFFECT OF ROLIPRAM ON TNF-ALPHA PRODUCTION IN MOUSE-BLOOD EX-VIVO IS DEPENDENT UPON THE RELEASE OF CORTICOSTERONE AND ADRENALINE
Authors: PETTIPHER ER ESKRA JD LABASI JM
Citation: Er. Pettipher et al., THE INHIBITORY EFFECT OF ROLIPRAM ON TNF-ALPHA PRODUCTION IN MOUSE-BLOOD EX-VIVO IS DEPENDENT UPON THE RELEASE OF CORTICOSTERONE AND ADRENALINE, Cytokine, 9(8), 1997, pp. 582-586
ANALGESIC ACTIVITY OF 2-AMINO-4-METHYLPYRIDINE, A NOVEL NO SYNTHASE INHIBITOR
Authors: PETTIPHER ER HIBBS TA SMITH MA GRIFFITHS RJ
Citation: Er. Pettipher et al., ANALGESIC ACTIVITY OF 2-AMINO-4-METHYLPYRIDINE, A NOVEL NO SYNTHASE INHIBITOR, Inflammation research, 46, 1997, pp. 135-136
BIARYLCARBOXAMIDE INHIBITORS OF PHOSPHODIESTERASE-IV AND TUMOR-NECROSIS-FACTOR-ALPHA
Authors: CHAMBERS RJ MARFAT A CHENG JB COHAN VL DAMON DB DUPLANTIER AJ HIBBS TA JENKINSON TH JOHNSON KL KRAUS KG PETTIPHER ER SALTER ED SHIRLEY JT UMLAND JP
Citation: Rj. Chambers et al., BIARYLCARBOXAMIDE INHIBITORS OF PHOSPHODIESTERASE-IV AND TUMOR-NECROSIS-FACTOR-ALPHA, Bioorganic & medicinal chemistry letters, 7(6), 1997, pp. 739-744
THE PHOSPHODIESTERASE TYPE-4 (PDE4) INHIBITOR CP-80,633 ELEVATES PLASMA CYCLIC-AMP LEVELS AND DECREASES TUMOR-NECROSIS-FACTOR-ALPHA (TNF-ALPHA) PRODUCTION IN MICE - EFFECT OF ADRENALECTOMY
Authors: CHENG JB WATSON JW PAZOLES CJ ESKRA JD GRIFFITHS RJ COHAN VL TURNER CR SHOWELL HJ PETTIPHER ER
Citation: Jb. Cheng et al., THE PHOSPHODIESTERASE TYPE-4 (PDE4) INHIBITOR CP-80,633 ELEVATES PLASMA CYCLIC-AMP LEVELS AND DECREASES TUMOR-NECROSIS-FACTOR-ALPHA (TNF-ALPHA) PRODUCTION IN MICE - EFFECT OF ADRENALECTOMY, The Journal of pharmacology and experimental therapeutics, 280(2), 1997, pp. 621-626
EFFECT OF THE INDUCIBLE NITRIC-OXIDE SYNTHASE INHIBITORS AMINOGUANIDINE AND L-N-6-(1-IMINOETHYL)LYSINE ON ZYMOSAN-INDUCED PLASMA EXTRAVASATION IN RAT SKIN
Authors: RIDGER VC PETTIPHER ER BRYANT CE BRAIN SD
Citation: Vc. Ridger et al., EFFECT OF THE INDUCIBLE NITRIC-OXIDE SYNTHASE INHIBITORS AMINOGUANIDINE AND L-N-6-(1-IMINOETHYL)LYSINE ON ZYMOSAN-INDUCED PLASMA EXTRAVASATION IN RAT SKIN, The Journal of immunology, 159(1), 1997, pp. 383-390
RESIDENT JOINT TISSUES, RATHER THAN INFILTRATING NEUTROPHILS AND MONOCYTES, ARE THE PREDOMINANT SOURCES OF TNF-ALPHA IN ZYMOSAN-INDUCED ARTHRITIS
Authors: PETTIPHER ER SALTER ED
Citation: Er. Pettipher et Ed. Salter, RESIDENT JOINT TISSUES, RATHER THAN INFILTRATING NEUTROPHILS AND MONOCYTES, ARE THE PREDOMINANT SOURCES OF TNF-ALPHA IN ZYMOSAN-INDUCED ARTHRITIS, Cytokine, 8(2), 1996, pp. 130-133
INHIBITION OF LEUKOTRIENE B-4-RECEPTOR INTERACTION SUPPRESSES EOSINOPHIL INFILTRATION AND DISEASE PATHOLOGY IN A MURINE MODEL OF EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS
Authors: GLADUE RP CARROLL LA MILICI AJ SCAMPOLI DN STUKENBROK HA PETTIPHER ER SALTER ED CONTILLO L SHOWELL HJ
Citation: Rp. Gladue et al., INHIBITION OF LEUKOTRIENE B-4-RECEPTOR INTERACTION SUPPRESSES EOSINOPHIL INFILTRATION AND DISEASE PATHOLOGY IN A MURINE MODEL OF EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS, The Journal of experimental medicine, 183(4), 1996, pp. 1893-1898
2-AMINO-4-METHYLPYRIDINE AS A POTENT INHIBITOR OF INDUCIBLE NO SYNTHASE ACTIVITY IN-VITRO AND IN-VIVO
Authors: FARACI WS NAGEL AA VERDRIES KA VINCENT LA XU H NICHOLS LE LABASI JM SALTER ED PETTIPHER ER
Citation: Ws. Faraci et al., 2-AMINO-4-METHYLPYRIDINE AS A POTENT INHIBITOR OF INDUCIBLE NO SYNTHASE ACTIVITY IN-VITRO AND IN-VIVO, British Journal of Pharmacology, 119(6), 1996, pp. 1101-1108
REGULATION OF TUMOR-NECROSIS-FACTOR PRODUCTION BY ADRENAL HORMONES IN-VIVO - INSIGHTS INTO THE ANTIINFLAMMATORY ACTIVITY OF ROLIPRAM
Authors: PETTIPHER ER LABASI JM SALTER ED STAM EJ CHENG JB GRIFFITHS RJ
Citation: Er. Pettipher et al., REGULATION OF TUMOR-NECROSIS-FACTOR PRODUCTION BY ADRENAL HORMONES IN-VIVO - INSIGHTS INTO THE ANTIINFLAMMATORY ACTIVITY OF ROLIPRAM, British Journal of Pharmacology, 117(7), 1996, pp. 1530-1534
IN-VITRO PHARMACOLOGY OF THE NOVEL TYPE-IV PHOSPHODIESTERASE (PDE(IV)) INHIBITOR, CP-80,633
Authors: COHAN VL SHOWELL HJ PETTIPHER ER FISHER DA PAZOLES CJ WATSON JW TURNER CR CHENG JB
Citation: Vl. Cohan et al., IN-VITRO PHARMACOLOGY OF THE NOVEL TYPE-IV PHOSPHODIESTERASE (PDE(IV)) INHIBITOR, CP-80,633, Journal of allergy and clinical immunology, 95(1), 1995, pp. 350-350
CP-80,633 ELEVATES PLASMA CAMP LEVELS AND DECREASES TNF PRODUCTION INMICE - EFFECT OF ADRENALECTOMY
Authors: CHENG JB WATSON JW SHOWELL HJ COHAN VL TURNER CR PETTIPHER ER
Citation: Jb. Cheng et al., CP-80,633 ELEVATES PLASMA CAMP LEVELS AND DECREASES TNF PRODUCTION INMICE - EFFECT OF ADRENALECTOMY, Journal of allergy and clinical immunology, 95(1), 1995, pp. 351-351
LEUKOTRIENE B-4 PLAYS A CRITICAL ROLE IN THE PROGRESSION OF COLLAGEN-INDUCED ARTHRITIS
Authors: GRIFFITHS RJ PETTIPHER ER KOCH K FARRELL CA BRESLOW R CONKLYN MJ SMITH MA HACKMAN BC WIMBERLY DJ MILICI AJ SCAMPOLI DN CHENG JB PILLAR JS PAZOLES CJ DOHERTY NS MELVIN LS REITER LA BIGGARS MS FALKNER FC MITCHELL DY LISTON TE SHOWELL HJ
Citation: Rj. Griffiths et al., LEUKOTRIENE B-4 PLAYS A CRITICAL ROLE IN THE PROGRESSION OF COLLAGEN-INDUCED ARTHRITIS, Proceedings of the National Academy of Sciences of the United Statesof America, 92(2), 1995, pp. 517-521
THE IN-VITRO AND IN-VIVO PHARMACOLOGICAL ACTIVITY OF THE POTENT AND SELECTIVE LEUKOTRIENE B-4 RECEPTOR ANTAGONIST CP-105696
Authors: SHOWELL HJ PETTIPHER ER CHENG JB BRESLOW R CONKLYN MJ FARRELL CA HINGORANI GP SALTER ED HACKMAN BC WIMBERLY DJ DOHERTY NS MELVIN LS REITER LA BIGGERS MS KOCH K
Citation: Hj. Showell et al., THE IN-VITRO AND IN-VIVO PHARMACOLOGICAL ACTIVITY OF THE POTENT AND SELECTIVE LEUKOTRIENE B-4 RECEPTOR ANTAGONIST CP-105696, The Journal of pharmacology and experimental therapeutics, 273(1), 1995, pp. 176-184
CYCLOOXYGENASE INHIBITORS ENHANCE TUMOR-NECROSIS-FACTOR PRODUCTION AND MORTALITY IN MURINE ENDOTOXIC-SHOCK
Authors: PETTIPHER ER WIMBERLY DJ
Citation: Er. Pettipher et Dj. Wimberly, CYCLOOXYGENASE INHIBITORS ENHANCE TUMOR-NECROSIS-FACTOR PRODUCTION AND MORTALITY IN MURINE ENDOTOXIC-SHOCK, Cytokine, 6(5), 1994, pp. 500-503
4-PHENYLBENZYL)-4-HYDROXYCHROMAN-7-YL]CYCLOPENTANE CARBOXYLIC-ACID, AHIGHLY POTENT, SELECTIVE LEUKOTRIENE B-4 ANTAGONIST WITH ORAL ACTIVITY IN THE MURINE COLLAGEN-INDUCED ARTHRITIS MODEL())
Authors: KOCH K MELVIN LS REITER LA BIGGERS MS SHOWELL HJ GRIFFITHS RJ PETTIPHER ER CHENG JB MILICI AJ BRESLOW R CONKLYN MJ SMITH MA HACKMAN BC DOHERTY NS SALTER E FARRELL CA SCHULTE G
Citation: K. Koch et al., 4-PHENYLBENZYL)-4-HYDROXYCHROMAN-7-YL]CYCLOPENTANE CARBOXYLIC-ACID, AHIGHLY POTENT, SELECTIVE LEUKOTRIENE B-4 ANTAGONIST WITH ORAL ACTIVITY IN THE MURINE COLLAGEN-INDUCED ARTHRITIS MODEL()), Journal of medicinal chemistry, 37(20), 1994, pp. 3197-3199
EFFECT OF IN-VIVO DESENSITIZATION TO LEUKOTRIENE B-4 ON EOSINOPHIL INFILTRATION IN RESPONSE TO C5A IN GUINEA-PIG SKIN
Authors: PETTIPHER ER SALTER ED SHOWELL HJ
Citation: Er. Pettipher et al., EFFECT OF IN-VIVO DESENSITIZATION TO LEUKOTRIENE B-4 ON EOSINOPHIL INFILTRATION IN RESPONSE TO C5A IN GUINEA-PIG SKIN, British Journal of Pharmacology, 113(1), 1994, pp. 117-120
SPECIFIC-INHIBITION OF LEUKOTRIENE B(4) (LTB4)-INDUCED NEUTROPHIL EMIGRATION BY 20-HYDROXY LTB(4) - IMPLICATIONS FOR THE REGULATION OF INFLAMMATORY RESPONSES
Authors: PETTIPHER ER SALTER ED BRESLOW R RAYCROFT L SHOWELL HJ
Citation: Er. Pettipher et al., SPECIFIC-INHIBITION OF LEUKOTRIENE B(4) (LTB4)-INDUCED NEUTROPHIL EMIGRATION BY 20-HYDROXY LTB(4) - IMPLICATIONS FOR THE REGULATION OF INFLAMMATORY RESPONSES, British Journal of Pharmacology, 110(1), 1993, pp. 423-427
Risultati: 1-19 |