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Results: 1-17 |
Results: 17
ORIGIN OF THE ANTICANCER ACTIVITY OF TOPOISOMERASE INHIBITORS
Authors: LIU LF DESAI SD SIM SP PILCH DS LI TK LAVOIE EJ SANDERS M DARPA P WANG H WU JX LIU A YU C
Citation: Lf. Liu et al., ORIGIN OF THE ANTICANCER ACTIVITY OF TOPOISOMERASE INHIBITORS, Annals of oncology, 9, 1998, pp. 40-40
DNA MINOR-GROOVE BINDING-DIRECTED POISONING OF HUMAN DNA TOPOISOMERASE-I BY TERBENZIMIDAZOLES
Authors: XU ZT LI TK KIM JS LAVOIE EJ BRESLAUER KJ LIU LF PILCH DS
Citation: Zt. Xu et al., DNA MINOR-GROOVE BINDING-DIRECTED POISONING OF HUMAN DNA TOPOISOMERASE-I BY TERBENZIMIDAZOLES, Biochemistry, 37(10), 1998, pp. 3558-3566
MODULATION OF NUCLEIC-ACID STRUCTURE BY LIGAND-BINDING - INDUCTION OFA DNA-CENTER-DOT-RNA-CENTER-DOT-DNA HYBRID TRIPLEX BY DAPI INTERCALATION
Authors: XU ZT PILCH DS SRINIVASAN AR OLSON WK GEACINTOV NE BRESLAUER KJ
Citation: Zt. Xu et al., MODULATION OF NUCLEIC-ACID STRUCTURE BY LIGAND-BINDING - INDUCTION OFA DNA-CENTER-DOT-RNA-CENTER-DOT-DNA HYBRID TRIPLEX BY DAPI INTERCALATION, Bioorganic & medicinal chemistry, 5(6), 1997, pp. 1137-1147
A TERBENZIMIDAZOLE THAT PREFERENTIALLY BINDS AND CONFORMATIONALLY ALTERS STRUCTURALLY DISTINCT DNA DUPLEX DOMAINS - A POTENTIAL MECHANISM FOR TOPOISOMERASE-I POISONING
Authors: PILCH DS XU ZT SUN Q LAVOIE EJ LIU LF BRESLAUER KJ
Citation: Ds. Pilch et al., A TERBENZIMIDAZOLE THAT PREFERENTIALLY BINDS AND CONFORMATIONALLY ALTERS STRUCTURALLY DISTINCT DNA DUPLEX DOMAINS - A POTENTIAL MECHANISM FOR TOPOISOMERASE-I POISONING, Proceedings of the National Academy of Sciences of the United Statesof America, 94(25), 1997, pp. 13565-13570
DIFFERENTIAL POISONING OF TOPOISOMERASES BY MENOGARIL AND NOGALAMYCINDICTATED BY THE MINOR GROOVE-BINDING NOGALOSE SUGAR
Authors: SIM SP GATTO B YU C LIU AA LI TK PILCH DS LAVOIE EJ LIU LF
Citation: Sp. Sim et al., DIFFERENTIAL POISONING OF TOPOISOMERASES BY MENOGARIL AND NOGALAMYCINDICTATED BY THE MINOR GROOVE-BINDING NOGALOSE SUGAR, Biochemistry, 36(43), 1997, pp. 13285-13291
MINOR GROOVE-DIRECTED AND INTERCALATIVE LIGAND-DNA INTERACTIONS IN THE POISONING OF HUMAN DNA TOPOISOMERASE-I BY PROTOBERBERINE ANALOGS
Authors: PILCH DS YU C MAKHEY D LAVOIE EJ SRINIVASAN AR OLSON WK SAUERS RR BRESLAUER KJ GEACINTOV NE LIU LF
Citation: Ds. Pilch et al., MINOR GROOVE-DIRECTED AND INTERCALATIVE LIGAND-DNA INTERACTIONS IN THE POISONING OF HUMAN DNA TOPOISOMERASE-I BY PROTOBERBERINE ANALOGS, Biochemistry, 36(41), 1997, pp. 12542-12553
BINDING OF A HAIRPIN POLYAMIDE IN THE MINOR-GROOVE OF DNA - SEQUENCE-SPECIFIC ENTHALPIC DISCRIMINATION
Authors: PILCH DS POKLAR N GELFAND CA LAW SM BRESLAUER KJ BAIRD EE DERVAN PB
Citation: Ds. Pilch et al., BINDING OF A HAIRPIN POLYAMIDE IN THE MINOR-GROOVE OF DNA - SEQUENCE-SPECIFIC ENTHALPIC DISCRIMINATION, Proceedings of the National Academy of Sciences of the United Statesof America, 93(16), 1996, pp. 8306-8311
INFLUENCE OF CISPLATIN INTRASTRAND CROSS-LINKING ON THE CONFORMATION,THERMAL-STABILITY, AND ENERGETICS OF A 20-MER DNA DUPLEX
Authors: POKLAR N PILCH DS LIPPARD SJ REDDING EA DUNHAM SU BRESLAUER KJ
Citation: N. Poklar et al., INFLUENCE OF CISPLATIN INTRASTRAND CROSS-LINKING ON THE CONFORMATION,THERMAL-STABILITY, AND ENERGETICS OF A 20-MER DNA DUPLEX, Proceedings of the National Academy of Sciences of the United Statesof America, 93(15), 1996, pp. 7606-7611
BIOPHYSICAL CHARACTERIZATION OF A CYTOTOXIC, TOPOISOMERASE I-POISONING TERBENZIMIDAZOLE AND ITS INTERACTIONS WITH A NATURAL DNA DUPLEX
Authors: PILCH DS XU ZT SUN Q LAVOIE EJ LIU LF GEACINTOV NE BRESLAUER KJ
Citation: Ds. Pilch et al., BIOPHYSICAL CHARACTERIZATION OF A CYTOTOXIC, TOPOISOMERASE I-POISONING TERBENZIMIDAZOLE AND ITS INTERACTIONS WITH A NATURAL DNA DUPLEX, Biophysical journal, 70(2), 1996, pp. 206-206
THERMODYNAMIC CHARACTERIZATION OF A DNA DUPLEX THAT CONTAINS A SINGLECIS-[PT(NH3)(2)(D(GPG)-N7(1),-N7(2))] INTRASTRAND CROSS-LINK
Authors: POKLAR N PILCH DS REDDING EA LIPPARD SJ BRESLAUER KJ
Citation: N. Poklar et al., THERMODYNAMIC CHARACTERIZATION OF A DNA DUPLEX THAT CONTAINS A SINGLECIS-[PT(NH3)(2)(D(GPG)-N7(1),-N7(2))] INTRASTRAND CROSS-LINK, Biophysical journal, 70(2), 1996, pp. 375-375
NUCLEIC-ACID HYBRIDIZATION - TRIPLEX STABILITY AND ENERGETICS
Authors: PLUM GE PILCH DS SINGLETON SF BRESLAUER KJ
Citation: Ge. Plum et al., NUCLEIC-ACID HYBRIDIZATION - TRIPLEX STABILITY AND ENERGETICS, Annual review of biophysics and biomolecular structure, 24, 1995, pp. 319-350
THE THERMODYNAMICS OF DNA STRUCTURES THAT CONTAIN LESIONS OR GUANINE TETRADS
Authors: PILCH DS PLUM GE BRESLAUER KJ
Citation: Ds. Pilch et al., THE THERMODYNAMICS OF DNA STRUCTURES THAT CONTAIN LESIONS OR GUANINE TETRADS, Current opinion in structural biology, 5(3), 1995, pp. 334-342
BERENIL BINDING TO HIGHER ORDERED NUCLEIC-ACID STRUCTURES - COMPLEXATION WITH A DNA AND RNA TRIPLE-HELIX
Authors: PILCH DS KIROLOS MA BRESLAUER KJ
Citation: Ds. Pilch et al., BERENIL BINDING TO HIGHER ORDERED NUCLEIC-ACID STRUCTURES - COMPLEXATION WITH A DNA AND RNA TRIPLE-HELIX, Biochemistry, 34(49), 1995, pp. 16107-16124
BERENIL [1,3-BIS(4'-AMIDINOPHENYL)TRIAZENE] BINDING TO DNA DUPLEXES AND TO A RNA DUPLEX - EVIDENCE FOR BOTH INTERCALATIVE AND MINOR-GROOVE BINDING-PROPERTIES
Authors: PILCH DS KIROLOS MA LIU XY PLUM GE BRESLAUER KJ
Citation: Ds. Pilch et al., BERENIL [1,3-BIS(4'-AMIDINOPHENYL)TRIAZENE] BINDING TO DNA DUPLEXES AND TO A RNA DUPLEX - EVIDENCE FOR BOTH INTERCALATIVE AND MINOR-GROOVE BINDING-PROPERTIES, Biochemistry, 34(31), 1995, pp. 9962-9976
LIGAND-INDUCED FORMATION OF NUCLEIC-ACID TRIPLE HELICES
Authors: PILCH DS BRESLAUER KJ
Citation: Ds. Pilch et Kj. Breslauer, LIGAND-INDUCED FORMATION OF NUCLEIC-ACID TRIPLE HELICES, Proceedings of the National Academy of Sciences of the United Statesof America, 91(20), 1994, pp. 9332-9336
CHARACTERIZATION OF A TRIPLE HELIX-SPECIFIC LIGAND - BEPI 3'-AMINO)PROPYLAMINO]-BENZO[E]PYRIDO[4,3-B]INDOLE) INTERCALATES INTO BOTH DOUBLE-HELICAL AND TRIPLE-HELICAL DNA
Authors: PILCH DS WARING MJ SUN JS ROUGEE M NGUYEN CH BISAGNI E GARESTIER T HELENE C
Citation: Ds. Pilch et al., CHARACTERIZATION OF A TRIPLE HELIX-SPECIFIC LIGAND - BEPI 3'-AMINO)PROPYLAMINO]-BENZO[E]PYRIDO[4,3-B]INDOLE) INTERCALATES INTO BOTH DOUBLE-HELICAL AND TRIPLE-HELICAL DNA, Journal of Molecular Biology, 232(3), 1993, pp. 926-946
SELF-ASSOCIATION AND DNA-BINDING PROPERTIES OF 2 TRIPLE HELIX-SPECIFIC LIGANDS - COMPARISON OF A BENZO[E]PYRIDOINDOLE AND A BENZO[G]PYRIDOINDOLE
Authors: PILCH DS MARTIN MT NGUYEN CH SUN JS BISAGNI E GARESTIER T HELENE C
Citation: Ds. Pilch et al., SELF-ASSOCIATION AND DNA-BINDING PROPERTIES OF 2 TRIPLE HELIX-SPECIFIC LIGANDS - COMPARISON OF A BENZO[E]PYRIDOINDOLE AND A BENZO[G]PYRIDOINDOLE, Journal of the American Chemical Society, 115(22), 1993, pp. 9942-9951
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