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Results: 1-25 |
Results: 25
MOLECULAR THERAPY FOR CANCER
Authors: DEISSEROTH A GUO D WANG T FUJII T FU SQ COTE R SAVINOV S LIU F LOEWE R PIZZORNO G AUSTIN D CRYSTAL R CHUNG I
Citation: A. Deisseroth et al., MOLECULAR THERAPY FOR CANCER, The cancer journal from Scientific American, 4, 1998, pp. 5-7
PHASE-I CLINICAL AND PHARMACOLOGICAL STUDIES OF BENZYLACYCLOURIDINE, A URIDINE PHOSPHORYLASE INHIBITOR
Authors: PIZZORNO G YEE L BURTNESS BA MARSH JC DARNOWSKI JW CHU MYW CHU SH CHU E LEFFERT JJ HANDSCHUMACHER RE CALABRESI P
Citation: G. Pizzorno et al., PHASE-I CLINICAL AND PHARMACOLOGICAL STUDIES OF BENZYLACYCLOURIDINE, A URIDINE PHOSPHORYLASE INHIBITOR, Clinical cancer research, 4(5), 1998, pp. 1165-1175
PHASE-I CLINICAL AND PHARMACOLOGICAL STUDIES OF BENZYLACYCLOURIDINE, A URIDINE PHOSPHORYLASE INHIBITOR
Authors: PIZZORNO G YEE L BURTNESS BA MARSH JC DARNOWSKI JW CHU MYW CHU SH CHU E LEFFERT JJ HANDSCHUMACHER RE CALABRESI P
Citation: G. Pizzorno et al., PHASE-I CLINICAL AND PHARMACOLOGICAL STUDIES OF BENZYLACYCLOURIDINE, A URIDINE PHOSPHORYLASE INHIBITOR, Clinical cancer research, 4(5), 1998, pp. 1165-1175
SERUM-FREE (SF) CONDITIONS PRESERVES RECONSTITUTING CAPABILITY OF HEMATOPOIETIC-CELLS (HC) AND RESULTS IN 1 MILLION FOLD REDUCTION OF BREAST-CANCER CELLS (BCC) WHICH CONTAMINATE HC WHEN USED WITH CYTOSINE DEAMINASE(CD) ADENOVIRAL VECTOR (AV) AND 5-FLUOROCYTOSINE (5FC)
Authors: WON JH GARCIASANCHEZ F NANAKORN T KRAUSE D COOPERBERG M LIN D BROWN R LIANG JC WANG RY BURTNESS B ZELTERMAN D PIZZORNO G CRYSTAL R DEISSEROTH A
Citation: Jh. Won et al., SERUM-FREE (SF) CONDITIONS PRESERVES RECONSTITUTING CAPABILITY OF HEMATOPOIETIC-CELLS (HC) AND RESULTS IN 1 MILLION FOLD REDUCTION OF BREAST-CANCER CELLS (BCC) WHICH CONTAMINATE HC WHEN USED WITH CYTOSINE DEAMINASE(CD) ADENOVIRAL VECTOR (AV) AND 5-FLUOROCYTOSINE (5FC), Experimental hematology, 26(8), 1998, pp. 62-62
DISCRETE ROLES OF HEPATOCYTES AND NONPARENCHYMAL CELLS IN URIDINE CATABOLISM AS A COMPONENT OF ITS HOMEOSTASIS
Authors: LIU MP BEIGELMAN L LEVY E HANDSCHUMACHER RE PIZZORNO G
Citation: Mp. Liu et al., DISCRETE ROLES OF HEPATOCYTES AND NONPARENCHYMAL CELLS IN URIDINE CATABOLISM AS A COMPONENT OF ITS HOMEOSTASIS, American journal of physiology: Gastrointestinal and liver physiology, 37(6), 1998, pp. 1018-1023
CYTOSINE DEAMINASE ADENOVIRAL VECTOR AND 5-FLUOROCYTOSINE SELECTIVELYREDUCE BREAST-CANCER CELLS 1 MILLION-FOLD WHEN THEY CONTAMINATE HEMATOPOIETIC-CELLS - A POTENTIAL PURGING METHOD FOR AUTOLOGOUS TRANSPLANTATION
Authors: GARCIASANCHEZ F PIZZORNO G FU SQ NANAKORN T KRAUSE DS LIANG J ADAMS E LEFFERT JJ YIN LH COOPERBERG MR HANANIA E WANG WL WON JH PENG XY COTE R BROWN R BURTNESS B GILES R CRYSTAL R DEISSEROTH AB
Citation: F. Garciasanchez et al., CYTOSINE DEAMINASE ADENOVIRAL VECTOR AND 5-FLUOROCYTOSINE SELECTIVELYREDUCE BREAST-CANCER CELLS 1 MILLION-FOLD WHEN THEY CONTAMINATE HEMATOPOIETIC-CELLS - A POTENTIAL PURGING METHOD FOR AUTOLOGOUS TRANSPLANTATION, Blood, 92(2), 1998, pp. 672-682
THE USE OF CHEMOTHERAPY RESISTANCE IN CANCER-TREATMENT
Authors: DEISSEROTH AB PIZZORNO G
Citation: Ab. Deisseroth et G. Pizzorno, THE USE OF CHEMOTHERAPY RESISTANCE IN CANCER-TREATMENT, The cancer journal from Scientific American, 3(2), 1997, pp. 60-69
F-19 NMR MONITORING OF IN-VIVO TUMOR METABOLISM AFTER BIOCHEMICAL MODULATION OF 5-FLUOROURACIL BY THE URIDINE PHOSPHORYLASE INHIBITOR 5-BENZYLACYCLOURIDINE
Authors: HOLLAND SK BERGMAN AM ZHAO YM ADAMS ER PIZZORNO G
Citation: Sk. Holland et al., F-19 NMR MONITORING OF IN-VIVO TUMOR METABOLISM AFTER BIOCHEMICAL MODULATION OF 5-FLUOROURACIL BY THE URIDINE PHOSPHORYLASE INHIBITOR 5-BENZYLACYCLOURIDINE, Magnetic resonance in medicine, 38(6), 1997, pp. 907-916
PHARMACOKINETIC AND PHASE-I TRIAL OF INTRAPERITONEAL CARBOPLATIN AND CYCLOSPORINE IN REFRACTORY OVARIAN-CANCER PATIENTS
Authors: CHAMBERS SK CHAMBERS JT DAVIS CA KOHORN EI SCHWARTZ PE LORBER MI HANDSCHUMACHER RE PIZZORNO G
Citation: Sk. Chambers et al., PHARMACOKINETIC AND PHASE-I TRIAL OF INTRAPERITONEAL CARBOPLATIN AND CYCLOSPORINE IN REFRACTORY OVARIAN-CANCER PATIENTS, Journal of clinical oncology, 15(5), 1997, pp. 1945-1952
DOSE-ESCALATION AND PHARMACODYNAMIC STUDY OF TOPOTECAN IN COMBINATIONWITH CYCLOPHOSPHAMIDE IN PATIENTS WITH REFRACTORY CANCER
Authors: MURREN JR ANDERSON S FEDELE J PIZZORNO G BELLIVEAU D ZELTERMAN D BURTNESS BA TOCINO I FLYNN SD BEIDLER D CHENG YC
Citation: Jr. Murren et al., DOSE-ESCALATION AND PHARMACODYNAMIC STUDY OF TOPOTECAN IN COMBINATIONWITH CYCLOPHOSPHAMIDE IN PATIENTS WITH REFRACTORY CANCER, Journal of clinical oncology, 15(1), 1997, pp. 148-157
STEM-CELL FACTOR MAINTAINS LONG-TERM ENGRAFTMENT POTENTIAL OF RECONSTITUTING HEMATOPOIETIC STEM-CELLS FOLLOWING INCUBATION FOR 4 DAYS IN SERUM-FREE IN-VITRO CULTURE SYSTEM
Authors: GARCIASANCHEZ F PIZZORNO G KRAUSE D LIANG J ADAMS E LEFFERT JJ FU SQ YIN LH HANNIA E COTE R GILES R CRYSTAL R BROWN R DEISSEROTH A
Citation: F. Garciasanchez et al., STEM-CELL FACTOR MAINTAINS LONG-TERM ENGRAFTMENT POTENTIAL OF RECONSTITUTING HEMATOPOIETIC STEM-CELLS FOLLOWING INCUBATION FOR 4 DAYS IN SERUM-FREE IN-VITRO CULTURE SYSTEM, Blood, 90(10), 1997, pp. 4603-4603
CYTOSINE DEAMINASE ADENOVIRAL VECTOR SYSTEM REDUCES LEVELS OF CONTAMINATING BREAST-CANCER CELLS ADMIXED WITH A 1000-FOLD EXCESS OF HEMATOPOIETIC-CELLS BY UP TO 500,000-FOLD FOLLOWING EXPOSURE TO 5-FLUOROCYTOSINE, WHICH IS CONVERTED TO 5-FLUOROURACIL BY THIS SYSTEM SELECTIVELY INTHE BREAST-CANCER CELLS
Authors: NANAKORN T GARCIASANCHEZ F FU SQ PIZZORNO G YIN LH KRAUSE DS ADAMS E LEFFERT JJ COTE R CRYSTAL R BROWN R DEISSEROTH A
Citation: T. Nanakorn et al., CYTOSINE DEAMINASE ADENOVIRAL VECTOR SYSTEM REDUCES LEVELS OF CONTAMINATING BREAST-CANCER CELLS ADMIXED WITH A 1000-FOLD EXCESS OF HEMATOPOIETIC-CELLS BY UP TO 500,000-FOLD FOLLOWING EXPOSURE TO 5-FLUOROCYTOSINE, WHICH IS CONVERTED TO 5-FLUOROURACIL BY THIS SYSTEM SELECTIVELY INTHE BREAST-CANCER CELLS, Blood, 90(10), 1997, pp. 2470-2470
USE OF A SAFETY RECOMBINANT ADENOVIRUS VECTOR FOR SELECTIVE BONE-MARROW PURGING CARRYING THE CHEMOSENSITIZATION GENE CYTOSINE DEAMINASE
Authors: GARCIASANCHEZ F PIZZORNO G ADAMS E HANANIA E GILES R CRYSTAL R DEISSEROTH AB
Citation: F. Garciasanchez et al., USE OF A SAFETY RECOMBINANT ADENOVIRUS VECTOR FOR SELECTIVE BONE-MARROW PURGING CARRYING THE CHEMOSENSITIZATION GENE CYTOSINE DEAMINASE, Experimental hematology, 24(9), 1996, pp. 619-619
RECEPTOR-DEPENDENT UPTAKE OF THE CYTOSINE DEAMINASE ADENOVIRAL VECTORINTO BREAST-CANCER BUT NOT HEMATOPOIETIC-CELLS FOR SENSITIZATION TO 5FLUOROCYTOSINE INDUCED CYTOXICITY
Authors: SANCHEZ FG PIZZORNO G CRYSTAL R DEISSEROTH AB
Citation: Fg. Sanchez et al., RECEPTOR-DEPENDENT UPTAKE OF THE CYTOSINE DEAMINASE ADENOVIRAL VECTORINTO BREAST-CANCER BUT NOT HEMATOPOIETIC-CELLS FOR SENSITIZATION TO 5FLUOROCYTOSINE INDUCED CYTOXICITY, Blood, 88(10), 1996, pp. 1918-1918
BIOCHEMICAL MODULATION OF 5-FLUOROURACIL WITH BREQUINAR - RESULTS OF A PHASE-I STUDY
Authors: BUZAID AC PIZZORNO G MARSH JC RAVIKUMAR TS MURREN JR TODD M STRAIR RK POO WJ HAIT WN
Citation: Ac. Buzaid et al., BIOCHEMICAL MODULATION OF 5-FLUOROURACIL WITH BREQUINAR - RESULTS OF A PHASE-I STUDY, Cancer chemotherapy and pharmacology, 36(5), 1995, pp. 373-378
TOXOPLASMA-GONDII TACHYZOITES POSSESS AN UNUSUAL PLASMA-MEMBRANE ADENOSINE TRANSPORTER
Authors: SCHWAB JC AFIFI MA PIZZORNO G HANDSCHUMACHER RE JOINER KA
Citation: Jc. Schwab et al., TOXOPLASMA-GONDII TACHYZOITES POSSESS AN UNUSUAL PLASMA-MEMBRANE ADENOSINE TRANSPORTER, Molecular and biochemical parasitology, 70(1-2), 1995, pp. 59-69
MULTIFACTORIAL RESISTANCE TO 5,10-DIDEAZATETRAHYDROFOLIC ACID IN CELL-LINES DERIVED FROM HUMAN LYMPHOBLASTIC-LEUKEMIA CCRF-CEM
Authors: PIZZORNO G MOROSON BA CASHMORE AR RUSSELLO O MAYER JR GALIVAN J BUNNI MA PRIEST DG BEARDSLEY GP
Citation: G. Pizzorno et al., MULTIFACTORIAL RESISTANCE TO 5,10-DIDEAZATETRAHYDROFOLIC ACID IN CELL-LINES DERIVED FROM HUMAN LYMPHOBLASTIC-LEUKEMIA CCRF-CEM, Cancer research, 55(3), 1995, pp. 566-573
5-FLUORO-2-PYRIMIDINONE, A LIVER ALDEHYDE OXIDASE-ACTIVATED PRODRUG OF 5-FLUOROURACIL
Authors: GUO X LERNERTUNG M CHEN HX CHANG CN ZHU JL CHANG CP PIZZORNO G LIN TS CHENG YC
Citation: X. Guo et al., 5-FLUORO-2-PYRIMIDINONE, A LIVER ALDEHYDE OXIDASE-ACTIVATED PRODRUG OF 5-FLUOROURACIL, Biochemical pharmacology, 49(8), 1995, pp. 1111-1116
ABERRANT CELL-CYCLE INHIBITION PATTERN IN HUMAN COLON-CARCINOMA CELL-LINES AFTER EXPOSURE TO 5-FLUOROURACIL
Authors: PIZZORNO G SUN Z HANDSCHUMACHER RE
Citation: G. Pizzorno et al., ABERRANT CELL-CYCLE INHIBITION PATTERN IN HUMAN COLON-CARCINOMA CELL-LINES AFTER EXPOSURE TO 5-FLUOROURACIL, Biochemical pharmacology, 49(4), 1995, pp. 553-557
EFFECT OF CLINICALLY MODELED REGIMENS ON THE GROWTH-RESPONSE AND DEVELOPMENT OF RESISTANCE IN HUMAN COLON-CARCINOMA CELL-LINES
Authors: PIZZORNO G HANDSCHUMACHER RE
Citation: G. Pizzorno et Re. Handschumacher, EFFECT OF CLINICALLY MODELED REGIMENS ON THE GROWTH-RESPONSE AND DEVELOPMENT OF RESISTANCE IN HUMAN COLON-CARCINOMA CELL-LINES, Biochemical pharmacology, 49(4), 1995, pp. 559-565
PERCUTANEOUS HEPATIC VEIN ISOLATION AND HIGH-DOSE HEPATIC ARTERIAL INFUSION CHEMOTHERAPY FOR UNRESECTABLE LIVER-TUMORS
Authors: RAVIKUMAR TS PIZZORNO G BODDEN W MARSH J STRAIR R POLLACK J HENDLER R HANNA J DANDREA E
Citation: Ts. Ravikumar et al., PERCUTANEOUS HEPATIC VEIN ISOLATION AND HIGH-DOSE HEPATIC ARTERIAL INFUSION CHEMOTHERAPY FOR UNRESECTABLE LIVER-TUMORS, Journal of clinical oncology, 12(12), 1994, pp. 2723-2736
TOPOTECAN AND CYCLOPHOSPHAMIDE - A PHASE-I STUDY
Authors: BAKAS MH SCHULTZ M ANDERSON S ENNEVER P BURTNESS B PIZZORNO G MURREN J
Citation: Mh. Bakas et al., TOPOTECAN AND CYCLOPHOSPHAMIDE - A PHASE-I STUDY, Clinical research, 42(2), 1994, pp. 10000128-10000128
ENHANCEMENT OF ANTINEOPLASTIC ACTIVITY OF 5-FLUOROURACIL IN MICE BEARING COLON-38 TUMOR BY (6R)5,10-DIDEAZATETRAHYDROFOLIC ACID
Authors: PIZZORNO G DAVIS SJ HARTIGAN DJ RUSSELLO O
Citation: G. Pizzorno et al., ENHANCEMENT OF ANTINEOPLASTIC ACTIVITY OF 5-FLUOROURACIL IN MICE BEARING COLON-38 TUMOR BY (6R)5,10-DIDEAZATETRAHYDROFOLIC ACID, Biochemical pharmacology, 47(11), 1994, pp. 1981-1988
EVIDENCE FOR A RELATIONSHIP BETWEEN INTRACELLULAR GTB LEVELS AND THE INDUCTION OF HL-60 LEUKEMIA-CELL DIFFERENTIATION BY 5,10-DIDEAZATETRAHYDROFOLIC ACID (DDATHF)
Authors: SOKOLOSKI JA PIZZORNO G BEARDSLEY GP SARTORELLI AC
Citation: Ja. Sokoloski et al., EVIDENCE FOR A RELATIONSHIP BETWEEN INTRACELLULAR GTB LEVELS AND THE INDUCTION OF HL-60 LEUKEMIA-CELL DIFFERENTIATION BY 5,10-DIDEAZATETRAHYDROFOLIC ACID (DDATHF), Oncology research, 5(8), 1993, pp. 293-299
BREQUINAR POTENTIATES 5-FLUOROURACIL ANTITUMOR-ACTIVITY IN A MURINE MODEL COLON-38 TUMOR BY TISSUE-SPECIFIC MODULATION OF URIDINE NUCLEOTIDE POOLS
Authors: PIZZORNO G WIEGAND RA LENTZ SK HANDSCHUMACHER RE
Citation: G. Pizzorno et al., BREQUINAR POTENTIATES 5-FLUOROURACIL ANTITUMOR-ACTIVITY IN A MURINE MODEL COLON-38 TUMOR BY TISSUE-SPECIFIC MODULATION OF URIDINE NUCLEOTIDE POOLS, Cancer research, 52(7), 1992, pp. 1660-1665
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