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Results: 1-25/119
Authors:
ROGAKOU EP
NIEVESNIERA W
BOON C
POMMIER Y
BONNER WM
Citation: Ep. Rogakou et al., HISTONE H2AX SERINE-139 PHOSPHORYLATION IS INDUCED BY THE INTRODUCTION OF THE INITIAL BREAKS INTO DNA AS A RESULT OF THE APOPTOTIC ENDONUCLEASE, Molecular biology of the cell, 9, 1998, pp. 629-629
Authors:
ZHANG JZ
NEAMATI N
POMMIER Y
NAIR V
Citation: Jz. Zhang et al., INHIBITION OF HIV INTEGRASE BY NOVEL NUCLEOTIDES BEARING TRICYCLIC BASES, Bioorganic & medicinal chemistry letters, 8(14), 1998, pp. 1887-1890
Authors:
TAKEBAYASHI Y
GOLDWASSER F
POMMIER Y
Citation: Y. Takebayashi et al., PROTEIN-LINKED DNA BREAKS INDUCED BY ECTEINASCIDIN-743 IN HUMAN COLON-CARCINOMA CELLS, Annals of oncology, 9, 1998, pp. 531-531
Authors:
POMMIER Y
Citation: Y. Pommier, DIVERSITY OF DNA TOPOISOMERASE-I AND INHIBITORS, Biochimie, 80(3), 1998, pp. 255-270
Authors:
POURQUIER P
JENSEN AD
GONG SS
POMMIER Y
ROGLER CE
Citation: P. Pourquier et al., TOPOISOMERASE-I ACTIVITIES OF LINEARIZATION, CIRCULARIZATION AND RELAXATION OF DUCK HEPATITIS-B VIRUS-DNA PROVIDE MECHANISMS FOR REGULATIONOF VIRAL REPLICATION, Hepatology, 28(4), 1998, pp. 2274-2274
Authors:
POMMIER Y
POURQUIER P
FAN Y
STRUMBERG D
Citation: Y. Pommier et al., MECHANISM OF ACTION OF EUKARYOTIC DNA TOPOISOMERASE-I AND DRUGS TARGETED TO THE ENZYME, Biochimica et biophysica acta, N. Gene structure and expression, 1400(1-3), 1998, pp. 83-106
Authors:
LUBKOWSKI J
YANG F
ALEXANDRATOS J
WLODAWER A
ZHAO H
BURKE TR
NEAMATI N
POMMIER Y
MERKEL G
SKALKA AM
Citation: J. Lubkowski et al., STRUCTURE OF THE CATALYTIC DOMAIN OF AVIAN-SARCOMA VIRUS INTEGRASE WITH A BOUND HIV-1 INTEGRASE-TARGETED INHIBITOR, Proceedings of the National Academy of Sciences of the United Statesof America, 95(9), 1998, pp. 4831-4836
Authors:
DRAKE RR
NEAMATI N
HONG HX
PILON AA
SUNTHANKAR P
HUME SD
MILNE GWA
POMMIER Y
Citation: Rr. Drake et al., IDENTIFICATION OF A NUCLEOTIDE-BINDING SITE IN HTV-1 INTEGRASE, Proceedings of the National Academy of Sciences of the United Statesof America, 95(8), 1998, pp. 4170-4175
Authors:
NEAMATI N
MAZUMDER A
SUNDER S
OWEN JM
TANDON M
LOWN JW
POMMIER Y
Citation: N. Neamati et al., HIGHLY POTENT SYNTHETIC POLYAMIDES, BISDISTAMYCINS, AND LEXITROPSINS AS INHIBITORS OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 INTEGRASE, Molecular pharmacology, 54(2), 1998, pp. 280-290
Authors:
KOHLHAGEN G
PAULL KD
CUSHMAN M
NAGAFUJI P
POMMIER Y
Citation: G. Kohlhagen et al., PROTEIN-LINKED DNA STRAND BREAKS INDUCED BY NSC-314622, A NOVEL NONCAMPTOTHECIN TOPOISOMERASE-I POISON, Molecular pharmacology, 54(1), 1998, pp. 50-58
Authors:
NEAMATI N
HONG HX
OWEN JM
SUNDER S
WINSLOW HE
CHRISTENSEN JL
ZHAO H
BURKE TR
MILNE GWA
POMMIER Y
Citation: N. Neamati et al., SALICYLHYDRAZINE-CONTAINING INHIBITORS OF HIV-1 INTEGRASE - IMPLICATION FOR A SELECTIVE CHELATION IN THE INTEGRASE ACTIVE-SITE, Journal of medicinal chemistry, 41(17), 1998, pp. 3202-3209
Authors:
FAN Y
WEINSTEIN JN
KOHN KW
SHI LM
POMMIER Y
Citation: Y. Fan et al., MOLECULAR MODELING STUDIES OF THE DNA-TOPOISOMERASE-I TERNARY CLEAVABLE COMPLEX WITH CAMPTOTHECIN, Journal of medicinal chemistry, 41(13), 1998, pp. 2216-2226
Authors:
POURQUIER P
BJORNSTI MA
POMMIER Y
Citation: P. Pourquier et al., INDUCTION OF TOPOISOMERASE-I CLEAVAGE COMPLEXES BY THE VINYL-CHLORIDEADDUCT 1,N-6-ETHENOADENINE, The Journal of biological chemistry, 273(42), 1998, pp. 27245-27249
Authors:
SHIMIZU T
CAO CX
SHAO RG
POMMIER Y
Citation: T. Shimizu et al., LAMIN-B PHOSPHORYLATION BY PROTEIN-KINASE-C-ALPHA AND PROTEOLYSIS DURING APOPTOSIS IN HUMAN LEUKEMIA HL60 CELLS, The Journal of biological chemistry, 273(15), 1998, pp. 8669-8674
Authors:
YOSHIDA A
POURQUIER P
POMMIER Y
Citation: A. Yoshida et al., PURIFICATION AND CHARACTERIZATION OF A MG2-DEPENDENT ENDONUCLEASE (AN34) FROM ETOPOSIDE-TREATED HUMAN LEUKEMIA HL-60 CELLS UNDERGOING APOPTOSIS(), Cancer research, 58(12), 1998, pp. 2576-2582
Authors:
PARKER BW
KAUR G
NIEVESNEIRA W
TAIMI M
KOHLHAGEN G
SHIMIZU T
LOSIEWICZ MD
POMMIER Y
SAUSVILLE EA
SENDEROWICZ AM
Citation: Bw. Parker et al., EARLY INDUCTION OF APOPTOSIS IN HEMATOPOIETIC-CELL LINES AFTER EXPOSURE TO FLAVOPIRIDOL, Blood, 91(2), 1998, pp. 458-465
Authors:
CHOURPA I
RIOU JF
MILLOT JM
POMMIER Y
MANFAIT M
Citation: I. Chourpa et al., MODULATION IN KINETICS OF LACTONE RING HYDROLYSIS OF CAMPTOTHECINS UPON INTERACTION WITH TOPOISOMERASE-I CLEAVAGE SITES ON DNA, Biochemistry, 37(20), 1998, pp. 7284-7291
Authors:
POMMIER Y
KOHLHAGEN G
WU CX
SIMMONS DT
Citation: Y. Pommier et al., MAMMALIAN DNA TOPOISOMERASE-I ACTIVITY AND POISONING BY CAMPTOTHECIN ARE INHIBITED BY SIMIAN-VIRUS-40 LARGE T-ANTIGEN, Biochemistry, 37(11), 1998, pp. 3818-3823
Authors:
NABIEV I
FLEURY F
KUDELINA I
POMMIER Y
CHARTON F
RIOU JF
ALIX AJP
MANFAIT M
Citation: I. Nabiev et al., SPECTROSCOPIC AND BIOCHEMICAL-CHARACTERIZATION OF SELF-AGGREGATES FORMED BY ANTITUMOR DRUGS OF THE CAMPTOTHECIN FAMILY - THEIR POSSIBLE ROLE IN THE UNIQUE MODE OF DRUG-ACTION, Biochemical pharmacology, 55(8), 1998, pp. 1163-1174
Authors:
NEAMATI N
SUNDER S
POMMIER Y
Citation: N. Neamati et al., DESIGN AND DISCOVERY OF HIV-1 INTEGRASE INHIBITORS, Drug discovery today, 2(11), 1997, pp. 487-498
Authors:
GUPTA M
FAN SJ
ZHAN QM
KOHN KW
OCONNOR PM
POMMIER Y
Citation: M. Gupta et al., INACTIVATION OF P53 INCREASES THE CYTOTOXICITY OF CAMPTOTHECIN IN HUMAN COLON HCT116 AND BREAST MCF-7 CANCER-CELLS, Clinical cancer research, 3(9), 1997, pp. 1653-1660
Authors:
BAGULEY BC
LETEURTRE F
RIOU JF
FINLAY GJ
POMMIER Y
Citation: Bc. Baguley et al., A CARBAMATE ANALOG OF AMSACRINE WITH ACTIVITY AGAINST NON-CYCLING CELLS STIMULATES TOPOISOMERASE-II CLEAVAGE AT DNA SITES DISTINCT FROM THOSE OF AMSACRINE, European journal of cancer, 33(2), 1997, pp. 272-279
Authors:
POMMIER Y
PILON AA
BAJAJ K
MAZUMDER A
NEAMATI N
Citation: Y. Pommier et al., HIV-1 INTEGRASE AS A TARGET FOR ANTIVIRAL DRUGS, Antiviral chemistry & chemotherapy, 8(6), 1997, pp. 463-483
Authors:
NEAMATI N
MAZUMDER A
SUNDER S
OWEN JM
SCHULTZ RJ
POMMIER Y
Citation: N. Neamati et al., 2-MERCAPTOBENZENESULPHONAMIDES AS NOVEL INHIBITORS OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-1 INTEGRASE AND REPLICATION, Antiviral chemistry & chemotherapy, 8(6), 1997, pp. 485-495
Authors:
SHIMIZU T
POMMIER Y
Citation: T. Shimizu et Y. Pommier, CAMPTOTHECIN-INDUCED APOPTOSIS IN P53-NULL HUMAN LEUKEMIA HL60 CELLS AND THEIR ISOLATED-NUCLEI - EFFECTS OF THE PROTEASE INHIBITORS Z-VAD-FMK AND DICHLOROISOCOUMARIN SUGGEST AN INVOLVEMENT OF BOTH CASPASES ANDSERINE PROTEASES, Leukemia, 11(8), 1997, pp. 1238-1244