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GSTZ1d: a new allele of glutathione transferase zeta and maleylacetoacetate isomerase
Authors: Blackburn, AC Coggan, M Tzeng, HF Lantum, H Polekhina, G Parker, MW Anders, MW Board, PG
Citation: Ac. Blackburn et al., GSTZ1d: a new allele of glutathione transferase zeta and maleylacetoacetate isomerase, PHARMACOGEN, 11(8), 2001, pp. 671-678
Human glutathione transferase T2-2 discloses some evolutionary strategies for optimization of substrate binding to the active site of glutathione transferases
Authors: Caccuri, AM Antonini, G Board, PG Flanagan, J Parker, MW Paolesse, R Turella, P Federici, G Lo Bello, M Ricci, G
Citation: Am. Caccuri et al., Human glutathione transferase T2-2 discloses some evolutionary strategies for optimization of substrate binding to the active site of glutathione transferases, J BIOL CHEM, 276(8), 2001, pp. 5427-5431
Human glutathione transferase T2-2 discloses some evolutionary strategies for optimization of the catalytic activity of glutathione transferases
Authors: Caccuri, AM Antonini, G Board, PG Flanagan, J Parker, MW Paolesse, R Turella, P Chelvanayagam, G Ricci, G
Citation: Am. Caccuri et al., Human glutathione transferase T2-2 discloses some evolutionary strategies for optimization of the catalytic activity of glutathione transferases, J BIOL CHEM, 276(8), 2001, pp. 5432-5437
Human glutathione transferase P1-1 and nitric oxide carriers - New role for an old enzyme
Authors: Lo Bello, M Nuccetelli, M Caccuri, AM Stella, L Parker, MW Rossjohn, J McKinstry, WJ Mozzi, AF Federici, G Polizio, F Pedersen, JZ Ricci, G
Citation: M. Lo Bello et al., Human glutathione transferase P1-1 and nitric oxide carriers - New role for an old enzyme, J BIOL CHEM, 276(45), 2001, pp. 42138-42145
Arresting pore formation of a cholesterol-dependent cytolysin by disulfidetrapping synchronizes the insertion of the transmembrane ss-sheet from a prepore intermediate
Authors: Hotze, EM Wilson-Kubalek, EM Rossjohnn, J Parker, MW Johnson, AE Tweten, RK
Citation: Em. Hotze et al., Arresting pore formation of a cholesterol-dependent cytolysin by disulfidetrapping synchronizes the insertion of the transmembrane ss-sheet from a prepore intermediate, J BIOL CHEM, 276(11), 2001, pp. 8261-8268
Dichloromethane mediated in vivo selection and functional characterizationof rat glutathione S-transferase theta 1-1 variants
Authors: Gisi, D Maillard, J Flanagan, JU Rossjohn, J Chelvanayagam, G Board, PG Parker, MW Leisinger, T Vuilleumier, S
Citation: D. Gisi et al., Dichloromethane mediated in vivo selection and functional characterizationof rat glutathione S-transferase theta 1-1 variants, EUR J BIOCH, 268(14), 2001, pp. 4001-4010
Evolution of functional diversity as observed through structural studies of glutathione transferases
Authors: Parker, MW McKinstry, WJ Oakley, AJ Polekhina, G Rossjohn, J Chelvanayagam, G Board, PG Di Ilio, C Caccuri, AM Ricci, G Lo Bello, M
Citation: Mw. Parker et al., Evolution of functional diversity as observed through structural studies of glutathione transferases, CHEM-BIO IN, 133(1-3), 2001, pp. 8-12
Limited proteolysis as a powerful tool for probing flexible oligopeptide portions among different classes of glutathione transferases
Authors: Nuccetelli, M Evangelisti, C Capo, C Petruzzelli, R Parker, MW Board, P Caccuri, AM Federici, G Ricci, G Lo Bello, M
Citation: M. Nuccetelli et al., Limited proteolysis as a powerful tool for probing flexible oligopeptide portions among different classes of glutathione transferases, CHEM-BIO IN, 133(1-3), 2001, pp. 43-48
Evolutionary strategy for optimization of GSH binding and catalysis in Alpha, Pi, Mu and Theta glutathione transferases
Authors: Caccuri, AM Antonini, G Board, PG Flanagan, J Parker, MW Paolesse, R Turella, P Federici, G Lo Bello, M Ricci, G
Citation: Am. Caccuri et al., Evolutionary strategy for optimization of GSH binding and catalysis in Alpha, Pi, Mu and Theta glutathione transferases, CHEM-BIO IN, 133(1-3), 2001, pp. 163-166
Site-directed mutagenesis of Histidine 106 and Lysine 107 residues in the Proteus mirabilis glutathione transferase B1-1
Authors: Allocati, N Masulli, M Casalone, E Polekhina, G Rossjohn, J Parker, MW
Citation: N. Allocati et al., Site-directed mutagenesis of Histidine 106 and Lysine 107 residues in the Proteus mirabilis glutathione transferase B1-1, CHEM-BIO IN, 133(1-3), 2001, pp. 182-184
Exit of products from the active site of human glutathione transferase P1-1 is promoted by valine 10
Authors: Micaloni, C Mazzetti, AP Nuccetelli, M Rossjohn, J McKinstry, WJ Antonini, G Caccuri, AM Oakley, AJ Federici, G Ricci, G Parker, MW Lo Bello, M
Citation: C. Micaloni et al., Exit of products from the active site of human glutathione transferase P1-1 is promoted by valine 10, CHEM-BIO IN, 133(1-3), 2001, pp. 192-195
Fly fishing for GSTs: a unified nomenclature for mammalian and insect glutathione transferases
Authors: Chelvanayagam, G Parker, MW Board, PG
Citation: G. Chelvanayagam et al., Fly fishing for GSTs: a unified nomenclature for mammalian and insect glutathione transferases, CHEM-BIO IN, 133(1-3), 2001, pp. 256-260
Crystal structure of maleylacetoacetate isomerase/glutathione transferase zeta reveals the molecular basis for its remarkable catalytic promiscuity
Authors: Polekhina, G Board, PG Blackburn, AC Parker, MW
Citation: G. Polekhina et al., Crystal structure of maleylacetoacetate isomerase/glutathione transferase zeta reveals the molecular basis for its remarkable catalytic promiscuity, BIOCHEM, 40(6), 2001, pp. 1567-1576
Cleaved antitrypsin polymers at atomic resolution
Authors: Dunstone, MA Dai, WW Whisstock, JC Rossjohn, J Pike, RN Feil, SC Le Bonniec, BF Parker, MW Bottomley, SP
Citation: Ma. Dunstone et al., Cleaved antitrypsin polymers at atomic resolution, PROTEIN SCI, 9(2), 2000, pp. 417-420
Ab initio calculations on hidden modulators of theta class glutathione transferase activity
Authors: Flanagan, JU King, W Parker, MW Board, PG Chelvanayagam, G
Citation: Ju. Flanagan et al., Ab initio calculations on hidden modulators of theta class glutathione transferase activity, PROTEINS, 39(3), 2000, pp. 235-243
Evaluation of the role of two conserved active-site residues in Beta classglutathione S-transferases
Authors: Allocati, N Casalone, E Masulli, M Polekhina, G Rossjohn, J Parker, MW Di Ilio, C
Citation: N. Allocati et al., Evaluation of the role of two conserved active-site residues in Beta classglutathione S-transferases, BIOCHEM J, 351, 2000, pp. 341-346
Kinetic properties of missense mutations in patients with glutathione synthetase deficiency
Authors: Njalsson, R Carlsson, K Olin, B Carlsson, B Whitbread, L Polekhina, G Parker, MW Norgren, S Mannervik, B Board, PG Larsson, A
Citation: R. Njalsson et al., Kinetic properties of missense mutations in patients with glutathione synthetase deficiency, BIOCHEM J, 349, 2000, pp. 275-279
Structures of thermolabile mutants of human glutathione transferase P1-1
Authors: Rossjohn, J McKinstry, WJ Oakley, AJ Parker, MW Stenberg, G Mannervik, B Dragani, B Cocco, R Aceto, A
Citation: J. Rossjohn et al., Structures of thermolabile mutants of human glutathione transferase P1-1, J MOL BIOL, 302(2), 2000, pp. 295-302
Structure of the activation domain of the GM-CSF/IL3/IL-5 receptor common beta-chain bound to an antagonist
Authors: Rossjohn, J McKinstry, WJ Woodcock, JM McClure, BJ Hercus, TR Parker, MW Lopez, AF Bagley, CJ
Citation: J. Rossjohn et al., Structure of the activation domain of the GM-CSF/IL3/IL-5 receptor common beta-chain bound to an antagonist, BLOOD, 95(8), 2000, pp. 2491-2498
Valine 10 may act as a driver for product release from the active site of human glutathione transferase P1-1
Authors: Micaloni, C Mazzetti, AP Nuccetelli, M Rossjohn, J McKinstry, WJ Antonini, G Caccuri, AM Oakley, AJ Federici, G Ricci, G Parker, MW Lo Bello, M
Citation: C. Micaloni et al., Valine 10 may act as a driver for product release from the active site of human glutathione transferase P1-1, BIOCHEM, 39(51), 2000, pp. 15961-15970
Crystal structure of the N-terminal, growth factor-like domain of Alzheimer amyloid precursor protein
Authors: Rossjohn, J Cappai, R Feil, SC Henry, A McKinstry, WJ Galatis, D Hesse, L Multhaup, G Beyreuther, K Masters, CL Parker, MW
Citation: J. Rossjohn et al., Crystal structure of the N-terminal, growth factor-like domain of Alzheimer amyloid precursor protein, NAT ST BIOL, 6(4), 1999, pp. 327-331
Mutagenic analysis of conserved arginine residues in and around the novel sulfate binding pocket of the human Theta class glutathione transferase T2-2
Authors: Flanagan, JU Rossjohn, J Parker, MW Board, PG Chelvanayagam, G
Citation: Ju. Flanagan et al., Mutagenic analysis of conserved arginine residues in and around the novel sulfate binding pocket of the human Theta class glutathione transferase T2-2, PROTEIN SCI, 8(10), 1999, pp. 2205-2212
Proton release on binding of glutathione to Alpha, Mu and Delta class glutathione transferases
Authors: Caccuri, AM Antonini, G Board, PG Parker, MW Nicotra, M Lo Bello, M Federici, G Ricci, G
Citation: Am. Caccuri et al., Proton release on binding of glutathione to Alpha, Mu and Delta class glutathione transferases, BIOCHEM J, 344, 1999, pp. 419-425
Molecular basis of glutathione synthetase deficiency and a rare gene permutation event
Authors: Polekhina, G Board, PG Gali, RR Rossjohn, J Parker, MW
Citation: G. Polekhina et al., Molecular basis of glutathione synthetase deficiency and a rare gene permutation event, EMBO J, 18(12), 1999, pp. 3204-3213
The mechanism of membrane insertion for a cholesterol-dependent cytolysin:A novel paradigm for pore-forming toxins
Authors: Shatursky, O Heuck, AP Shepard, LA Rossjohn, J Parker, MW Johnson, AE Tweten, RK
Citation: O. Shatursky et al., The mechanism of membrane insertion for a cholesterol-dependent cytolysin:A novel paradigm for pore-forming toxins, CELL, 99(3), 1999, pp. 293-299
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